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FI934680L - Arylmorfolin, framstaellning och anvaending - Google Patents

Arylmorfolin, framstaellning och anvaending Download PDF

Info

Publication number
FI934680L
FI934680L FI934680A FI934680A FI934680L FI 934680 L FI934680 L FI 934680L FI 934680 A FI934680 A FI 934680A FI 934680 A FI934680 A FI 934680A FI 934680 L FI934680 L FI 934680L
Authority
FI
Finland
Prior art keywords
arylmorfolin
anvaending
framstaellning och
framstaellning
och
Prior art date
Application number
FI934680A
Other languages
English (en)
Other versions
FI934680A7 (fi
FI934680A0 (fi
Inventor
Nariman Bomanshaw Mehta
Grady Evan Boswell
James Leroy Kelley
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI934680A7 publication Critical patent/FI934680A7/fi
Publication of FI934680L publication Critical patent/FI934680L/fi
Publication of FI934680A0 publication Critical patent/FI934680A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
FI934680A 1991-04-23 1992-04-22 Arylmorfolin, framstaellning och anvaending FI934680A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919108629A GB9108629D0 (en) 1991-04-23 1991-04-23 Heterocyclic pharmaceutical compounds,preparation and use
PCT/GB1992/000733 WO1992018489A1 (en) 1991-04-23 1992-04-22 Arylmorpholine, preparation and use

Publications (3)

Publication Number Publication Date
FI934680A7 FI934680A7 (fi) 1993-10-22
FI934680L true FI934680L (fi) 1993-10-22
FI934680A0 FI934680A0 (fi) 1993-10-22

Family

ID=10693740

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934680A FI934680A0 (fi) 1991-04-23 1992-04-22 Arylmorfolin, framstaellning och anvaending

Country Status (17)

Country Link
US (2) US5648347A (fi)
EP (1) EP0583271B1 (fi)
JP (1) JP3130040B2 (fi)
AT (1) ATE173252T1 (fi)
AU (1) AU668863B2 (fi)
CA (1) CA2108967C (fi)
DE (1) DE69227583T2 (fi)
DK (1) DK0583271T3 (fi)
ES (1) ES2124256T3 (fi)
FI (1) FI934680A0 (fi)
GB (1) GB9108629D0 (fi)
HU (1) HU219458B (fi)
IE (1) IE921260A1 (fi)
NZ (1) NZ242421A (fi)
PT (1) PT100415B (fi)
WO (1) WO1992018489A1 (fi)
ZA (1) ZA922910B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
US7098206B2 (en) * 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
HRP20051024A2 (hr) 1998-01-21 2006-04-30 Glaxo Group Limited Farmaceutski aktivni morfolinol
US6998400B2 (en) 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6855820B2 (en) * 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
FR2796069B3 (fr) * 1999-07-09 2001-08-24 Sanofi Synthelabo Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes
EA009589B1 (ru) * 2002-12-10 2008-02-28 Пфайзер Инк. Производные морфолина для применения в качестве агонистов допамина при лечении половой дисфункции
US7323462B2 (en) 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
GB0228787D0 (en) * 2002-12-10 2003-01-15 Pfizer Ltd Morpholine dopamine agonists
EP2571859B1 (en) 2010-05-21 2015-07-22 Research Triangle Institute 1-phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
WO2011146850A1 (en) * 2010-05-21 2011-11-24 Research Triangle Institute Phenylmorpholines and analogues thereof
CN105949142B (zh) * 2016-05-21 2018-03-27 南华大学 具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2997469A (en) * 1961-08-22 Preparation of substituted
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
GB1336732A (en) * 1970-10-28 1973-11-07 Istituto Gentili Spa Pisa Diethanolamine derivatives
IE50355B1 (en) * 1979-10-20 1986-04-02 Wyeth John & Brother Ltd Morpholine derivatives
FR2517305B1 (fr) * 1981-12-01 1985-10-25 Lafon Labor Nouveaux derives de 2-phenyl-morpholine et leur utilisation en therapeutique
FR2553410B1 (fr) * 1983-10-14 1986-05-16 Lafon Labor Nouveaux derives de 2-tolyl-morpholine utiles en therapeutique
FR2553411B1 (fr) * 1983-10-14 1986-08-01 Lafon Labor Derives de 2-halogenophenyl-morpholine, procede de preparation et utilisation en therapeutique
FR2553413B1 (fr) * 1983-10-17 1986-03-21 Lafon Labor Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) * 1984-07-05 1984-08-08 Wellcome Found Heterocyclic pharmaceutical compounds
US4803200A (en) * 1987-10-02 1989-02-07 A. H. Robins Company, Incorporated Substituted dialkanolamines, sulfur analogs and condensed 1,4-oxazine derivatives thereof in viral disease treatment
GB8924528D0 (en) * 1989-10-31 1989-12-20 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use

Also Published As

Publication number Publication date
JPH06506675A (ja) 1994-07-28
PT100415B (pt) 1999-08-31
FI934680A7 (fi) 1993-10-22
WO1992018489A1 (en) 1992-10-29
EP0583271A1 (en) 1994-02-23
HU219458B (hu) 2001-04-28
HUT70531A (en) 1995-10-30
AU668863B2 (en) 1996-05-23
EP0583271B1 (en) 1998-11-11
ES2124256T3 (es) 1999-02-01
US5760224A (en) 1998-06-02
PT100415A (pt) 1993-06-30
DE69227583D1 (de) 1998-12-17
ATE173252T1 (de) 1998-11-15
NZ242421A (en) 1994-10-26
JP3130040B2 (ja) 2001-01-31
FI934680A0 (fi) 1993-10-22
IE921260A1 (en) 1992-11-04
CA2108967C (en) 2002-10-08
AU1575392A (en) 1992-11-17
DE69227583T2 (de) 1999-04-01
DK0583271T3 (da) 1999-07-26
HU9303000D0 (en) 1994-01-28
ZA922910B (en) 1994-01-24
CA2108967A1 (en) 1992-10-24
GB9108629D0 (en) 1991-06-12
US5648347A (en) 1997-07-15

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Legal Events

Date Code Title Description
MA Patent expired