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FI56375C - Saosom mellanprodukt anvaendbar beta-hydroxy-beta-3,4,5-trialkoxyfenetylmetylsulfon eller sulfoxid foer framstaellning av antibakteriska 2,4-diamino-5-bensylpyrimidiner - Google Patents

Saosom mellanprodukt anvaendbar beta-hydroxy-beta-3,4,5-trialkoxyfenetylmetylsulfon eller sulfoxid foer framstaellning av antibakteriska 2,4-diamino-5-bensylpyrimidiner Download PDF

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Publication number
FI56375C
FI56375C FI1338/70A FI133870A FI56375C FI 56375 C FI56375 C FI 56375C FI 1338/70 A FI1338/70 A FI 1338/70A FI 133870 A FI133870 A FI 133870A FI 56375 C FI56375 C FI 56375C
Authority
FI
Finland
Prior art keywords
beta
diamino
hydroxy
sulfoxide
reaction
Prior art date
Application number
FI1338/70A
Other languages
English (en)
Finnish (fi)
Other versions
FI56375B (fi
Inventor
Ronald Morton Cresswell
John William Mentha
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of FI56375B publication Critical patent/FI56375B/fi
Publication of FI56375C publication Critical patent/FI56375C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI1338/70A 1969-05-16 1970-05-13 Saosom mellanprodukt anvaendbar beta-hydroxy-beta-3,4,5-trialkoxyfenetylmetylsulfon eller sulfoxid foer framstaellning av antibakteriska 2,4-diamino-5-bensylpyrimidiner FI56375C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2517169 1969-05-16
GB2517169 1969-05-16

Publications (2)

Publication Number Publication Date
FI56375B FI56375B (fi) 1979-09-28
FI56375C true FI56375C (fi) 1980-01-10

Family

ID=10223379

Family Applications (1)

Application Number Title Priority Date Filing Date
FI1338/70A FI56375C (fi) 1969-05-16 1970-05-13 Saosom mellanprodukt anvaendbar beta-hydroxy-beta-3,4,5-trialkoxyfenetylmetylsulfon eller sulfoxid foer framstaellning av antibakteriska 2,4-diamino-5-bensylpyrimidiner

Country Status (14)

Country Link
JP (1) JPS505184B1 (sv)
AT (1) AT308082B (sv)
BR (1) BR6915082D0 (sv)
CA (1) CA994812A (sv)
CH (1) CH544071A (sv)
DE (1) DE2023977C2 (sv)
ES (3) ES379700A1 (sv)
FI (1) FI56375C (sv)
FR (1) FR2070070A1 (sv)
IL (1) IL34433A (sv)
IT (1) IT1021507B (sv)
NL (2) NL173395C (sv)
PL (1) PL92440B1 (sv)
SE (2) SE400777B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1469521A (en) * 1973-01-05 1977-04-06 Wellcome Found Antimicrobial preparations
US4687861A (en) * 1984-11-28 1987-08-18 Ciba-Geigy Corporation Microbicidal compositions
ES2548022T3 (es) * 2004-03-05 2015-10-13 F. Hoffmann-La Roche Ag Diaminopirimidinas como antagonistas de P2X3 y P2X2/3

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049544A (en) * 1962-08-14 Method for the preparation of
DE1103931B (de) 1957-02-21 1961-04-06 Wellcome Found Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten
DE1303727B (de) 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (sv) * 1960-09-02
DE1620729A1 (de) 1965-07-08 1970-08-20 Wellcome Found Verfahren zur Herstellung von substituierten Benzylpyrimidinen
GB1261455A (en) 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles

Also Published As

Publication number Publication date
SE400777B (sv) 1978-04-10
NL7007108A (sv) 1970-11-18
NL8004796A (nl) 1980-11-28
CH544071A (de) 1973-11-15
IT1021507B (it) 1978-02-20
BR6915082D0 (pt) 1973-03-08
IL34433A0 (en) 1970-07-19
ES379700A1 (es) 1973-01-16
ES406726A1 (es) 1975-10-01
FR2070070B1 (sv) 1974-10-11
FR2070070A1 (en) 1971-09-10
DE2023977C2 (de) 1984-03-15
NL173395B (nl) 1983-08-16
SE398878B (sv) 1978-01-23
FI56375B (fi) 1979-09-28
AT308082B (de) 1973-06-25
CA994812A (en) 1976-08-10
PL92440B1 (en) 1977-04-30
DE2023977A1 (de) 1971-02-18
JPS505184B1 (sv) 1975-02-28
NL173395C (nl) 1984-01-16
IL34433A (en) 1971-10-20
ES406725A1 (es) 1975-10-01

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