CA994812A - Intermediates in the preparation of benzylpyrimidines - Google Patents

Intermediates in the preparation of benzylpyrimidines

Info

Publication number: CA994812A
Authority: CA; Canada
Prior art keywords: benzylpyrimidines; intermediates; preparation
Prior art date: 1969-05-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA083,401A

Other languages

English (en)

Inventor

John W. Mentha

Ronald M. Cresswell

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wellcome Foundation Ltd

Original Assignee

Wellcome Foundation Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-05-16

Filing date

1970-05-19

Publication date

1976-08-10

1970-05-19 Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd

1976-08-10 Application granted granted Critical

1976-08-10 Publication of CA994812A publication Critical patent/CA994812A/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

CA083,401A 1969-05-16 1970-05-19 Intermediates in the preparation of benzylpyrimidines Expired CA994812A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2517169		1969-05-16

Publications (1)

Publication Number	Publication Date
CA994812A true CA994812A (en)	1976-08-10

Family

ID=10223379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA083,401A Expired CA994812A (en)	1969-05-16	1970-05-19	Intermediates in the preparation of benzylpyrimidines

Country Status (14)

Country	Link
JP (1)	JPS505184B1 (sv)
AT (1)	AT308082B (sv)
BR (1)	BR6915082D0 (sv)
CA (1)	CA994812A (sv)
CH (1)	CH544071A (sv)
DE (1)	DE2023977C2 (sv)
ES (3)	ES379700A1 (sv)
FI (1)	FI56375C (sv)
FR (1)	FR2070070A1 (sv)
IL (1)	IL34433A (sv)
IT (1)	IT1021507B (sv)
NL (2)	NL173395C (sv)
PL (1)	PL92440B1 (sv)
SE (2)	SE400777B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1469521A (en) *	1973-01-05	1977-04-06	Wellcome Found	Antimicrobial preparations
US4687861A (en) *	1984-11-28	1987-08-18	Ciba-Geigy Corporation	Microbicidal compositions
ES2548022T3 (es) *	2004-03-05	2015-10-13	F. Hoffmann-La Roche Ag	Diaminopirimidinas como antagonistas de P2X3 y P2X2/3

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3049544A (en) *		1962-08-14		Method for the preparation of
DE1103931B (de)	1957-02-21	1961-04-06	Wellcome Found	Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten
DE1303727B (de)	1959-09-03	1976-02-05	Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London	Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (sv) *	1960-09-02
DE1620729A1 (de)	1965-07-08	1970-08-20	Wellcome Found	Verfahren zur Herstellung von substituierten Benzylpyrimidinen
GB1261455A (en)	1969-03-06	1972-01-26	Burroughs Wellcome Co	Improvements in or relating to substituted acrylonitriles

1969
- 1969-12-12 BR BR215082/69A patent/BR6915082D0/pt unknown
1970
- 1970-03-05 PL PL1970177150A patent/PL92440B1/pl unknown
- 1970-03-06 AT AT100472A patent/AT308082B/de active
- 1970-05-01 IL IL34433A patent/IL34433A/xx unknown
- 1970-05-13 FI FI1338/70A patent/FI56375C/fi active
- 1970-05-14 ES ES379700A patent/ES379700A1/es not_active Expired
- 1970-05-15 IT IT50715/70A patent/IT1021507B/it active
- 1970-05-15 DE DE2023977A patent/DE2023977C2/de not_active Expired
- 1970-05-15 JP JP45041540A patent/JPS505184B1/ja active Pending
- 1970-05-15 CH CH732370A patent/CH544071A/de not_active IP Right Cessation
- 1970-05-15 NL NLAANVRAGE7007108,A patent/NL173395C/xx not_active IP Right Cessation
- 1970-05-15 SE SE7006713A patent/SE400777B/sv unknown
- 1970-05-15 FR FR7017799A patent/FR2070070A1/fr active Granted
- 1970-05-19 CA CA083,401A patent/CA994812A/en not_active Expired
1972
- 1972-09-15 ES ES406726A patent/ES406726A1/es not_active Expired
- 1972-09-15 ES ES406725A patent/ES406725A1/es not_active Expired
1973
- 1973-06-07 SE SE7308030A patent/SE398878B/sv unknown
1980
- 1980-08-25 NL NL8004796A patent/NL8004796A/nl not_active Application Discontinuation

Also Published As

Publication number	Publication date
SE400777B (sv)	1978-04-10
NL7007108A (sv)	1970-11-18
NL8004796A (nl)	1980-11-28
CH544071A (de)	1973-11-15
IT1021507B (it)	1978-02-20
BR6915082D0 (pt)	1973-03-08
IL34433A0 (en)	1970-07-19
ES379700A1 (es)	1973-01-16
FI56375C (fi)	1980-01-10
ES406726A1 (es)	1975-10-01
FR2070070B1 (sv)	1974-10-11
FR2070070A1 (en)	1971-09-10
DE2023977C2 (de)	1984-03-15
NL173395B (nl)	1983-08-16
SE398878B (sv)	1978-01-23
FI56375B (fi)	1979-09-28
AT308082B (de)	1973-06-25
PL92440B1 (en)	1977-04-30
DE2023977A1 (de)	1971-02-18
JPS505184B1 (sv)	1975-02-28
NL173395C (nl)	1984-01-16
IL34433A (en)	1971-10-20
ES406725A1 (es)	1975-10-01

Publication	Publication Date	Title
CA979460A (en)	1975-12-09	Phenoxy-hydroxypropylamines and their preparation
CA994812A (en)	1976-08-10	Intermediates in the preparation of benzylpyrimidines
CA946413A (en)	1974-04-30	Preparation of polyfluoroolifins
CA1000740A (en)	1976-11-30	Intermediates in the preparation of benzylpyrimidines
AU3548368A (en)	1970-10-01	Cosmetic preparation
CA892576A (en)	1972-02-08	Aminolignosulfonates and preparation thereof
CA971120A (en)	1975-07-15	Intermediates in brewing
CA813927A (en)	1969-05-27	Isocyanatophenols and the preparation of ureidophenols
CA944883A (en)	1974-04-02	Preparation of polyimidazopyrrolones
AU443085B2 (en)	1971-04-29	Preparation of 19-norsteroids
CA804058A (en)	1969-01-14	Preparation of hexachlorodibenzyl
CA806711A (en)	1969-02-18	Preparation of tetrahaloacetone
CA807669A (en)	1969-03-04	Preparation of zearalane
CA809224A (en)	1969-03-25	Preparation of aminohydrins
CA822157A (en)	1969-09-02	Preparation of 4a-lower-alkyl naphthalenones
CA811160A (en)	1969-04-22	Preparation of 6-chloropyrazinoylguanidines
CA824716A (en)	1969-10-07	Preparation of perfluoroalkylbenzenes
CA811198A (en)	1969-04-22	Preparation of polymethyladamantanes
CA825180A (en)	1969-10-14	Preparation of 5-hydrocarbyltetrazoles
CA812275A (en)	1969-05-06	Preparation of decatrienes
CA817916A (en)	1969-07-15	Preparation of bromomethylsilanes
CA818576A (en)	1969-07-22	Preparation of amine-ethers
CA818580A (en)	1969-07-22	Preparation of vinylmercaptans
CA810716A (en)	1969-04-15	Preparation of pentafluoroiodoethane
CA810184A (en)	1969-04-08	Preparation of decachlorobutane