FI111642B - Menetelmä 10b-H-steroidien valmistamiseksi - Google Patents

Menetelmä 10b-H-steroidien valmistamiseksi Download PDF

Info

Publication number: FI111642B
Authority: FI; Finland
Prior art keywords: group; hydrogen atom; formula; atom; alkyl
Prior art date: 1990-06-01

Application number

FI925445A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI925445L (fi

FI925445A0 (fi

Inventor

Rudolf Wiechert

Eckhard Ottow

Arwed Cleve

Guenter Neef

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-01

Filing date

1992-11-30

Publication date

2003-08-29

1992-11-30 Application filed by Schering Ag filed Critical Schering Ag

1992-11-30 Publication of FI925445L publication Critical patent/FI925445L/fi

1992-11-30 Publication of FI925445A0 publication Critical patent/FI925445A0/fi

2003-08-29 Application granted granted Critical

2003-08-29 Publication of FI111642B publication Critical patent/FI111642B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)

FI925445A 1990-06-01 1992-11-30 Menetelmä 10b-H-steroidien valmistamiseksi FI111642B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE4018167A DE4018167A1 (de)	1990-06-01	1990-06-01	Verfahren zur herstellung von 10(beta)-h-steroiden
DE4018167		1990-06-01
PCT/EP1991/001018 WO1991018918A1 (de)	1990-06-01	1991-06-03	VERFAHREN ZUR HERSTELLUNG VON 10β-H-STEROIDEN
EP9101018		1991-06-03

Publications (3)

Publication Number	Publication Date
FI925445L FI925445L (fi)	1992-11-30
FI925445A0 FI925445A0 (fi)	1992-11-30
FI111642B true FI111642B (fi)	2003-08-29

Family

ID=6407912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI925445A FI111642B (fi)	1990-06-01	1992-11-30	Menetelmä 10b-H-steroidien valmistamiseksi

Country Status (12)

Country	Link
US (1)	US5405979A (hu)
EP (1)	EP0532562B1 (hu)
JP (1)	JP2999258B2 (hu)
AT (1)	ATE114317T1 (hu)
CA (1)	CA2084313C (hu)
DE (2)	DE4018167A1 (hu)
DK (1)	DK0532562T3 (hu)
ES (1)	ES2065039T3 (hu)
FI (1)	FI111642B (hu)
HU (1)	HU218484B (hu)
NO (1)	NO304115B1 (hu)
WO (1)	WO1991018918A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4042007A1 (de) *	1990-12-22	1992-06-25	Schering Ag	6,7-modifizierte-11(beta)-aryl-4-estrene
DE19610667C2 (de) *	1996-03-08	1998-04-09	Schering Ag	(Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
DE102011004899A1 (de)	2011-03-01	2012-09-06	Bayer Pharma Aktiengesellschaft	17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
AU2016377702B2 (en)	2015-12-23	2021-03-11	Oric Pharmaceuticals, Inc.	Inhibitors of glucocorticoid receptor
JP6995757B2 (ja)	2015-12-23	2022-01-17	オリックファーマシューティカルズ，インク．	グルココルチコイド受容体の阻害剤
US11110103B2 (en)	2015-12-23	2021-09-07	Oric Pharmaceuticals, Inc.	Inhibitors of glucocorticoid receptor
KR102237916B1 (ko)	2016-10-07	2021-04-09	오릭 파마슈티칼스, 인크.	글루코코르티코이드 수용체의 억제제
CA3095042A1 (en) *	2018-04-11	2019-10-17	Oric Pharmaceuticals, Inc.	Solid forms and formulations comprising a glucocorticoid receptor antagonist and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3014120A1 (de) *	1980-04-12	1981-10-29	Hoechst Ag, 6000 Frankfurt	Verfahren zur synthese von oestron bzw. oestronderivaten
AU572589B2 (en) *	1983-12-14	1988-05-12	Upjohn Company, The	11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
IE60780B1 (en) *	1987-01-23	1994-08-10	Akzo Nv	New 11-aryl steroid derivatives

1990
- 1990-06-01 DE DE4018167A patent/DE4018167A1/de not_active Withdrawn
1991
- 1991-06-03 JP JP3509553A patent/JP2999258B2/ja not_active Expired - Fee Related
- 1991-06-03 WO PCT/EP1991/001018 patent/WO1991018918A1/de active IP Right Grant
- 1991-06-03 ES ES91910189T patent/ES2065039T3/es not_active Expired - Lifetime
- 1991-06-03 DE DE59103592T patent/DE59103592D1/de not_active Expired - Fee Related
- 1991-06-03 DK DK91910189.9T patent/DK0532562T3/da active
- 1991-06-03 HU HU9203775A patent/HU218484B/hu not_active IP Right Cessation
- 1991-06-03 AT AT91910189T patent/ATE114317T1/de not_active IP Right Cessation
- 1991-06-03 US US07/952,739 patent/US5405979A/en not_active Expired - Lifetime
- 1991-06-03 EP EP91910189A patent/EP0532562B1/de not_active Expired - Lifetime
- 1991-06-03 CA CA002084313A patent/CA2084313C/en not_active Expired - Fee Related
1992
- 1992-11-30 FI FI925445A patent/FI111642B/fi active
- 1992-11-30 NO NO924617A patent/NO304115B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2065039T3 (es)	1995-02-01
NO924617L (no)	1992-11-30
HUT62596A (en)	1993-05-28
CA2084313C (en)	2002-12-10
EP0532562B1 (de)	1994-11-23
US5405979A (en)	1995-04-11
WO1991018918A1 (de)	1991-12-12
FI925445L (fi)	1992-11-30
EP0532562A1 (de)	1993-03-24
HU9203775D0 (en)	1993-03-29
DE59103592D1 (de)	1995-01-12
JPH05507271A (ja)	1993-10-21
JP2999258B2 (ja)	2000-01-17
CA2084313A1 (en)	1991-12-02
NO924617D0 (no)	1992-11-30
DK0532562T3 (da)	1995-05-15
DE4018167A1 (de)	1991-12-05
HU218484B (hu)	2000-09-28
NO304115B1 (no)	1998-10-26
ATE114317T1 (de)	1994-12-15
FI925445A0 (fi)	1992-11-30

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