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FI925445L - Foerfarande foer framstaellning av 10b-h-steroider - Google Patents

Foerfarande foer framstaellning av 10b-h-steroider Download PDF

Info

Publication number
FI925445L
FI925445L FI925445A FI925445A FI925445L FI 925445 L FI925445 L FI 925445L FI 925445 A FI925445 A FI 925445A FI 925445 A FI925445 A FI 925445A FI 925445 L FI925445 L FI 925445L
Authority
FI
Finland
Prior art keywords
steroider
foerfarande foer
foer framstaellning
framstaellning
foerfarande
Prior art date
Application number
FI925445A
Other languages
English (en)
Other versions
FI111642B (fi
FI925445A0 (fi
Inventor
Eckhard Ottow
Guenter Neef
Arwed Cleve
Rudolf Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI925445L publication Critical patent/FI925445L/fi
Publication of FI925445A0 publication Critical patent/FI925445A0/fi
Application granted granted Critical
Publication of FI111642B publication Critical patent/FI111642B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/008Ketals at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J33/00Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FI925445A 1990-06-01 1992-11-30 Menetelmä 10b-H-steroidien valmistamiseksi FI111642B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4018167A DE4018167A1 (de) 1990-06-01 1990-06-01 Verfahren zur herstellung von 10(beta)-h-steroiden
DE4018167 1990-06-01
PCT/EP1991/001018 WO1991018918A1 (de) 1990-06-01 1991-06-03 VERFAHREN ZUR HERSTELLUNG VON 10β-H-STEROIDEN
EP9101018 1991-06-03

Publications (3)

Publication Number Publication Date
FI925445L true FI925445L (fi) 1992-11-30
FI925445A0 FI925445A0 (fi) 1992-11-30
FI111642B FI111642B (fi) 2003-08-29

Family

ID=6407912

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925445A FI111642B (fi) 1990-06-01 1992-11-30 Menetelmä 10b-H-steroidien valmistamiseksi

Country Status (12)

Country Link
US (1) US5405979A (fi)
EP (1) EP0532562B1 (fi)
JP (1) JP2999258B2 (fi)
AT (1) ATE114317T1 (fi)
CA (1) CA2084313C (fi)
DE (2) DE4018167A1 (fi)
DK (1) DK0532562T3 (fi)
ES (1) ES2065039T3 (fi)
FI (1) FI111642B (fi)
HU (1) HU218484B (fi)
NO (1) NO304115B1 (fi)
WO (1) WO1991018918A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4042007A1 (de) * 1990-12-22 1992-06-25 Schering Ag 6,7-modifizierte-11(beta)-aryl-4-estrene
DE19610667C2 (de) * 1996-03-08 1998-04-09 Schering Ag (Z)-11ß-[4-(Dimethylamino)phenyl]17ß-hydroxy-17alpha-(3-hydroxy-1-propenyl)estr-4-en-3-on als kristallines Ansolvat
DE102011004899A1 (de) 2011-03-01 2012-09-06 Bayer Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
AU2016377702B2 (en) 2015-12-23 2021-03-11 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6995757B2 (ja) 2015-12-23 2022-01-17 オリック ファーマシューティカルズ,インク. グルココルチコイド受容体の阻害剤
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
KR102237916B1 (ko) 2016-10-07 2021-04-09 오릭 파마슈티칼스, 인크. 글루코코르티코이드 수용체의 억제제
CA3095042A1 (en) * 2018-04-11 2019-10-17 Oric Pharmaceuticals, Inc. Solid forms and formulations comprising a glucocorticoid receptor antagonist and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3014120A1 (de) * 1980-04-12 1981-10-29 Hoechst Ag, 6000 Frankfurt Verfahren zur synthese von oestron bzw. oestronderivaten
AU572589B2 (en) * 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives

Also Published As

Publication number Publication date
ES2065039T3 (es) 1995-02-01
NO924617L (no) 1992-11-30
HUT62596A (en) 1993-05-28
CA2084313C (en) 2002-12-10
EP0532562B1 (de) 1994-11-23
US5405979A (en) 1995-04-11
WO1991018918A1 (de) 1991-12-12
FI111642B (fi) 2003-08-29
EP0532562A1 (de) 1993-03-24
HU9203775D0 (en) 1993-03-29
DE59103592D1 (de) 1995-01-12
JPH05507271A (ja) 1993-10-21
JP2999258B2 (ja) 2000-01-17
CA2084313A1 (en) 1991-12-02
NO924617D0 (no) 1992-11-30
DK0532562T3 (da) 1995-05-15
DE4018167A1 (de) 1991-12-05
HU218484B (hu) 2000-09-28
NO304115B1 (no) 1998-10-26
ATE114317T1 (de) 1994-12-15
FI925445A0 (fi) 1992-11-30

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