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FI105189B - Menetelmä uusien glykosfingolipidien valmistamiseksi - Google Patents

Menetelmä uusien glykosfingolipidien valmistamiseksi Download PDF

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Publication number
FI105189B
FI105189B FI940851A FI940851A FI105189B FI 105189 B FI105189 B FI 105189B FI 940851 A FI940851 A FI 940851A FI 940851 A FI940851 A FI 940851A FI 105189 B FI105189 B FI 105189B
Authority
FI
Finland
Prior art keywords
integer
compound
synthesis
formula
mhz
Prior art date
Application number
FI940851A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI940851A0 (fi
FI940851A (fi
Inventor
Teruyuki Sakai
Yasuhiko Koezuka
Tatsuo Higa
Koji Akimoto
Masahiro Morita
Takenori Natori
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of FI940851A0 publication Critical patent/FI940851A0/fi
Publication of FI940851A publication Critical patent/FI940851A/fi
Application granted granted Critical
Publication of FI105189B publication Critical patent/FI105189B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
FI940851A 1991-08-29 1994-02-23 Menetelmä uusien glykosfingolipidien valmistamiseksi FI105189B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP24438491 1991-08-29
JP3244384A JPH0559081A (ja) 1991-08-29 1991-08-29 新規スフインゴ糖脂質、その製造法および使用
JP9200561 1992-04-28
PCT/JP1992/000561 WO1993005055A1 (en) 1991-08-29 1992-04-28 Novel sphingoglycolipid and use thereof

Publications (3)

Publication Number Publication Date
FI940851A0 FI940851A0 (fi) 1994-02-23
FI940851A FI940851A (fi) 1994-02-23
FI105189B true FI105189B (fi) 2000-06-30

Family

ID=17117885

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940851A FI105189B (fi) 1991-08-29 1994-02-23 Menetelmä uusien glykosfingolipidien valmistamiseksi

Country Status (19)

Country Link
EP (1) EP0609437B1 (pt)
JP (2) JPH0559081A (pt)
KR (1) KR100220793B1 (pt)
AT (1) ATE181922T1 (pt)
AU (1) AU665536B2 (pt)
CA (1) CA2116442C (pt)
DE (1) DE69229557T2 (pt)
DK (1) DK0609437T3 (pt)
ES (1) ES2134213T3 (pt)
FI (1) FI105189B (pt)
GR (1) GR3030723T3 (pt)
HK (1) HK1009967A1 (pt)
HU (1) HU223839B1 (pt)
NO (1) NO180338C (pt)
PT (1) PT100736B (pt)
SG (1) SG44031A1 (pt)
TW (1) TW197446B (pt)
WO (1) WO1993005055A1 (pt)
ZA (1) ZA923239B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (pt) * 1992-07-16 1995-11-01 Kirin Brewery
AU683026B2 (en) * 1992-10-22 1997-10-30 Kirin Pharma Kabushiki Kaisha Novel shingoglycolipid and use thereof
DE69416306T2 (de) * 1993-04-15 1999-06-17 Kirin Beer K.K., Tokio/Tokyo Sphingoglycolipid und verwendung davon
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
NZ519957A (en) * 2000-01-14 2003-08-29 Meiji Dairies Corp Antigen-specific IgE antibody production inhibitors
JP2002030093A (ja) * 2000-03-13 2002-01-29 Nof Corp グリコシルセラミドの精製方法
CA2459482C (en) * 2001-08-16 2010-09-28 Daiichi Suntory Pharma Co., Ltd. Novel glycolipid and medicine for autoimmune disease containing the same as active ingredient
KR20050062551A (ko) * 2002-09-20 2005-06-23 기린 비루 가부시키가이샤 α-글리코실세라미드를 유효 성분으로 하는 C형 간염 바이러스 억제제
JP4585172B2 (ja) * 2003-01-31 2010-11-24 森永乳業株式会社 骨形成促進剤
AU2004210784A1 (en) * 2003-02-14 2004-08-26 Asubio Pharma Co., Ltd. Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates
WO2006068041A1 (ja) * 2004-12-20 2006-06-29 Okayasu Shoten Co., Ltd. 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤
JP2007070311A (ja) * 2005-09-09 2007-03-22 Gunma Univ α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
WO2008047174A1 (en) * 2006-10-18 2008-04-24 Centre National De La Recherche Scientifique Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
WO2008101951A1 (en) 2007-02-21 2008-08-28 Vib Vzw Combination therapy using tnf and alfa-galactosyl ceramide
JP4995172B2 (ja) * 2008-10-10 2012-08-08 壽製薬株式会社 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬
PT2939683T (pt) 2009-02-16 2017-04-07 Cerenis Therapeutics Holding Sa Miméticos da apolipoproteína a-i
JP5095683B2 (ja) * 2009-07-06 2012-12-12 壽製薬株式会社 新規糖脂質誘導体及びこれを有効成分とする製剤
JP5025692B2 (ja) * 2009-07-06 2012-09-12 壽製薬株式会社 糖脂質誘導体の製造方法
JP2010254718A (ja) * 2010-08-13 2010-11-11 Morinaga Milk Ind Co Ltd 骨形成促進剤
NO2629776T3 (pt) 2010-10-18 2018-01-13
WO2012074116A1 (ja) 2010-12-02 2012-06-07 独立行政法人理化学研究所 アロNKT細胞を用いた免疫療法およびそのためのT細胞抗原受容体(TCR)遺伝子のα鎖領域が均一なVα-Jαに再構成されている細胞および該細胞由来NKT細胞のバンキング
EP2881400A4 (en) * 2012-08-03 2016-02-24 Riken HYDROXYLATED KRN7000 ANALOGON AND USE THEREOF
JP2015531384A (ja) 2012-10-03 2015-11-02 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル インバリアントnkt細胞アゴニストを用いたインフルエンザ後の細菌重複感染の予防的処置のための方法及び薬学的組成物
AU2013349706B2 (en) 2012-11-21 2019-08-22 Assistance Publique - Hopitaux De Paris Methods for determining the risk of acute graft versus host disease
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
KR102328367B1 (ko) * 2019-11-05 2021-11-18 한국해양과학기술원 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물
AU2021392472A1 (en) 2020-12-04 2023-07-06 Osaka University Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0609437B1 (en) 1999-07-07
SG44031A1 (en) 1997-11-14
FI940851A0 (fi) 1994-02-23
ATE181922T1 (de) 1999-07-15
KR100220793B1 (ko) 1999-10-01
AU1666492A (en) 1993-04-05
HK1009967A1 (en) 1999-09-17
WO1993005055A1 (en) 1993-03-18
TW197446B (pt) 1993-01-01
JPH0559081A (ja) 1993-03-09
PT100736A (pt) 1993-09-30
FI940851A (fi) 1994-02-23
JP2774194B2 (ja) 1998-07-09
EP0609437A1 (en) 1994-08-10
CA2116442C (en) 2000-09-05
DE69229557T2 (de) 1999-11-25
ES2134213T3 (es) 1999-10-01
PT100736B (pt) 1999-04-30
HUT70435A (en) 1995-10-30
HU9400596D0 (en) 1994-05-30
NO180338C (no) 1997-04-02
EP0609437A4 (en) 1994-08-24
GR3030723T3 (en) 1999-11-30
AU665536B2 (en) 1996-01-11
CA2116442A1 (en) 1993-03-18
DE69229557D1 (de) 1999-08-12
NO940598L (pt) 1994-04-27
NO180338B (no) 1996-12-23
NO940598D0 (no) 1994-02-22
HU223839B1 (hu) 2005-02-28
DK0609437T3 (da) 2000-01-31
ZA923239B (en) 1993-05-05

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Owner name: KIRIN PHARMA KABUSHIKI KAISHA

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PC Transfer of assignment of patent

Owner name: KYOWA HAKKO KIRIN CO., LTD.

Free format text: KYOWA HAKKO KIRIN CO., LTD.

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