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ZA923239B - Glycosphingolipids and the use thereof. - Google Patents

Glycosphingolipids and the use thereof.

Info

Publication number
ZA923239B
ZA923239B ZA923239A ZA923239A ZA923239B ZA 923239 B ZA923239 B ZA 923239B ZA 923239 A ZA923239 A ZA 923239A ZA 923239 A ZA923239 A ZA 923239A ZA 923239 B ZA923239 B ZA 923239B
Authority
ZA
South Africa
Prior art keywords
sphingoglycolipid
integer
glycosphingolipids
chem
isopropyl
Prior art date
Application number
ZA923239A
Other languages
English (en)
Inventor
Tatsuo Higal
Koji Akimoto
Yasuhiko Koezuka
Teruyuki Sakai
Masahiro Morita
Takenori Natori
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of ZA923239B publication Critical patent/ZA923239B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
ZA923239A 1991-08-29 1992-05-05 Glycosphingolipids and the use thereof. ZA923239B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3244384A JPH0559081A (ja) 1991-08-29 1991-08-29 新規スフインゴ糖脂質、その製造法および使用

Publications (1)

Publication Number Publication Date
ZA923239B true ZA923239B (en) 1993-05-05

Family

ID=17117885

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923239A ZA923239B (en) 1991-08-29 1992-05-05 Glycosphingolipids and the use thereof.

Country Status (19)

Country Link
EP (1) EP0609437B1 (xx)
JP (2) JPH0559081A (xx)
KR (1) KR100220793B1 (xx)
AT (1) ATE181922T1 (xx)
AU (1) AU665536B2 (xx)
CA (1) CA2116442C (xx)
DE (1) DE69229557T2 (xx)
DK (1) DK0609437T3 (xx)
ES (1) ES2134213T3 (xx)
FI (1) FI105189B (xx)
GR (1) GR3030723T3 (xx)
HK (1) HK1009967A1 (xx)
HU (1) HU223839B1 (xx)
NO (1) NO180338C (xx)
PT (1) PT100736B (xx)
SG (1) SG44031A1 (xx)
TW (1) TW197446B (xx)
WO (1) WO1993005055A1 (xx)
ZA (1) ZA923239B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (xx) * 1992-07-16 1995-11-01 Kirin Brewery
AU683026B2 (en) * 1992-10-22 1997-10-30 Kirin Pharma Kabushiki Kaisha Novel shingoglycolipid and use thereof
DE69416306T2 (de) * 1993-04-15 1999-06-17 Kirin Beer K.K., Tokio/Tokyo Sphingoglycolipid und verwendung davon
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
NZ519957A (en) * 2000-01-14 2003-08-29 Meiji Dairies Corp Antigen-specific IgE antibody production inhibitors
JP2002030093A (ja) * 2000-03-13 2002-01-29 Nof Corp グリコシルセラミドの精製方法
CA2459482C (en) * 2001-08-16 2010-09-28 Daiichi Suntory Pharma Co., Ltd. Novel glycolipid and medicine for autoimmune disease containing the same as active ingredient
KR20050062551A (ko) * 2002-09-20 2005-06-23 기린 비루 가부시키가이샤 α-글리코실세라미드를 유효 성분으로 하는 Ｃ형 간염 바이러스 억제제
JP4585172B2 (ja) * 2003-01-31 2010-11-24 森永乳業株式会社 骨形成促進剤
AU2004210784A1 (en) * 2003-02-14 2004-08-26 Asubio Pharma Co., Ltd. Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates
WO2006068041A1 (ja) * 2004-12-20 2006-06-29 Okayasu Shoten Co., Ltd. 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤
JP2007070311A (ja) * 2005-09-09 2007-03-22 Gunma Univ α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
WO2008047174A1 (en) * 2006-10-18 2008-04-24 Centre National De La Recherche Scientifique Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
WO2008101951A1 (en) 2007-02-21 2008-08-28 Vib Vzw Combination therapy using tnf and alfa-galactosyl ceramide
JP4995172B2 (ja) * 2008-10-10 2012-08-08 壽製薬株式会社 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬
PT2939683T (pt) 2009-02-16 2017-04-07 Cerenis Therapeutics Holding Sa Miméticos da apolipoproteína a-i
JP5095683B2 (ja) * 2009-07-06 2012-12-12 壽製薬株式会社 新規糖脂質誘導体及びこれを有効成分とする製剤
JP5025692B2 (ja) * 2009-07-06 2012-09-12 壽製薬株式会社 糖脂質誘導体の製造方法
JP2010254718A (ja) * 2010-08-13 2010-11-11 Morinaga Milk Ind Co Ltd 骨形成促進剤
NO2629776T3 (xx) 2010-10-18 2018-01-13
WO2012074116A1 (ja) 2010-12-02 2012-06-07 独立行政法人理化学研究所 アロNKT細胞を用いた免疫療法およびそのためのT細胞抗原受容体（TCR）遺伝子のα鎖領域が均一なVα-Jαに再構成されている細胞および該細胞由来NKT細胞のバンキング
EP2881400A4 (en) * 2012-08-03 2016-02-24 Riken HYDROXYLATED KRN7000 ANALOGON AND USE THEREOF
JP2015531384A (ja) 2012-10-03 2015-11-02 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル インバリアントｎｋｔ細胞アゴニストを用いたインフルエンザ後の細菌重複感染の予防的処置のための方法及び薬学的組成物
AU2013349706B2 (en) 2012-11-21 2019-08-22 Assistance Publique - Hopitaux De Paris Methods for determining the risk of acute graft versus host disease
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
KR102328367B1 (ko) * 2019-11-05 2021-11-18 한국해양과학기술원 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물
AU2021392472A1 (en) 2020-12-04 2023-07-06 Osaka University Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0609437B1 (en) 1999-07-07
SG44031A1 (en) 1997-11-14
FI940851A0 (fi) 1994-02-23
ATE181922T1 (de) 1999-07-15
KR100220793B1 (ko) 1999-10-01
AU1666492A (en) 1993-04-05
HK1009967A1 (en) 1999-09-17
FI105189B (fi) 2000-06-30
WO1993005055A1 (en) 1993-03-18
TW197446B (xx) 1993-01-01
JPH0559081A (ja) 1993-03-09
PT100736A (pt) 1993-09-30
FI940851A (fi) 1994-02-23
JP2774194B2 (ja) 1998-07-09
EP0609437A1 (en) 1994-08-10
CA2116442C (en) 2000-09-05
DE69229557T2 (de) 1999-11-25
ES2134213T3 (es) 1999-10-01
PT100736B (pt) 1999-04-30
HUT70435A (en) 1995-10-30
HU9400596D0 (en) 1994-05-30
NO180338C (no) 1997-04-02
EP0609437A4 (en) 1994-08-24
GR3030723T3 (en) 1999-11-30
AU665536B2 (en) 1996-01-11
CA2116442A1 (en) 1993-03-18
DE69229557D1 (de) 1999-08-12
NO940598L (xx) 1994-04-27
NO180338B (no) 1996-12-23
NO940598D0 (no) 1994-02-22
HU223839B1 (hu) 2005-02-28
DK0609437T3 (da) 2000-01-31

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