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ES8106909A1 - Un procedimiento para preparar fibras de colageno reconsti- tuido macromoleculares - Google Patents

Un procedimiento para preparar fibras de colageno reconsti- tuido macromoleculares

Info

Publication number
ES8106909A1
ES8106909A1 ES494963A ES494963A ES8106909A1 ES 8106909 A1 ES8106909 A1 ES 8106909A1 ES 494963 A ES494963 A ES 494963A ES 494963 A ES494963 A ES 494963A ES 8106909 A1 ES8106909 A1 ES 8106909A1
Authority
ES
Spain
Prior art keywords
collagen
biologically active
hours
frozen
article
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494963A
Other languages
English (en)
Other versions
ES494963A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seton Co
Original Assignee
Seton Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seton Co filed Critical Seton Co
Publication of ES8106909A1 publication Critical patent/ES8106909A1/es
Publication of ES494963A0 publication Critical patent/ES494963A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43Hormones, e.g. dexamethasone
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/08Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR FIBRAS DE COLAGENO RECONSTITUIDO MACROMOLECULAR. CONSISTE EN TRATAR COLAGENO INSOLUBLE NATURAL CON UNA SOLUCION ACUOSA DE SULFATO DE SODIO DE CONCENTRACION APROXIMADA A UNO MOLAR E HIDROXIDO DE SODIO DE CONCENTRACION APROXIMADA A DOS MOLAR. SE PROCEDE DE ESTA FORMA DURANTE CUARENTA Y OCHO HORAS PARA SAPONIFICAR LAS GRASAS SUSPENDIDAS EN EL COLAGENO NATURAL E HINCHAR LAS FIBRAS DE DICHO COLAGENO. LIBRE DE GRASA, SE TRATA CON SULFATO DE METAL ALCALINO DURANTE CUATRO HORAS; DE ESTA FORMA SE ESTABILIZAN LAS UNIONES ENTRE FIBRAS. SE DISUELVE EL COLAGENO EN SOLUCION DE ACIDO ASORBICO DE PH CUATRO, SE CONGELA DICHA SOLUCION A UNA VELOCIDAD DE REDUCCION DE LA TEMPERATURA DE -18G A -14GC POR HORA Y SE SECA DURANTE DOCE HORAS. DE APLICACION EN ALIMENTACION, COSMETICA Y FARMACIA.
ES494963A 1979-09-12 1980-09-11 Un procedimiento para preparar fibras de colageno reconsti- tuido macromoleculares Granted ES494963A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/074,738 US4279812A (en) 1979-09-12 1979-09-12 Process for preparing macromolecular biologically active collagen

Publications (2)

Publication Number Publication Date
ES8106909A1 true ES8106909A1 (es) 1981-09-01
ES494963A0 ES494963A0 (es) 1981-09-01

Family

ID=22121392

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494963A Granted ES494963A0 (es) 1979-09-12 1980-09-11 Un procedimiento para preparar fibras de colageno reconsti- tuido macromoleculares

Country Status (9)

Country Link
US (1) US4279812A (es)
JP (1) JPS5695195A (es)
CA (1) CA1147726A (es)
CH (1) CH647947A5 (es)
DE (1) DE3034273A1 (es)
ES (1) ES494963A0 (es)
FR (1) FR2464962A1 (es)
GB (2) GB2058084B (es)
IT (1) IT1128187B (es)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374121A (en) * 1979-09-12 1983-02-15 Seton Company Macromolecular biologically active collagen articles
US4412947A (en) * 1979-09-12 1983-11-01 Seton Company Collagen sponge
US4522753A (en) * 1980-07-17 1985-06-11 Massachusetts Institute Of Technology Method for preserving porosity in porous materials
US4440680A (en) * 1980-09-24 1984-04-03 Seton Company Macromolecular biologically active collagen articles
DE3124981A1 (de) * 1981-06-25 1983-01-13 Dr. Ruhland Nachfolger GmbH, 8425 Neustadt Wirkstoffhaltige kollageneinlage zum einfuehren in knochen oder weichteile und verfahren zu deren herstellung
US4432888A (en) * 1981-09-30 1984-02-21 Seton Company Surface active agents based on polypeptides
US4415628A (en) * 1981-10-26 1983-11-15 Seton Company Moisture vapor permeable sheet materials
US4590022A (en) * 1981-10-26 1986-05-20 Seton Company Method of forming a moisture permeable polymeric sheet material
US4424208A (en) 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4505855A (en) * 1982-09-30 1985-03-19 Massachusetts General Hospital Transparent non-fibrilized collagen material by ultracentrifugation
JPS59164723A (ja) * 1983-03-10 1984-09-17 Koken:Kk 再生コラーゲンフイブリルを含有する基質及びその製造方法
US4494994A (en) * 1983-03-28 1985-01-22 Seton Company Surface active agent compositions containing polypeptides and lignin sulfonic acid
US4861714A (en) * 1985-04-04 1989-08-29 Verax Corporation Weighted collagen microsponge for immobilizing bioactive material
DE3522626A1 (de) * 1985-06-25 1987-01-08 Merz & Co Gmbh & Co Loeslicher kollagen-schwamm
ES2054613T3 (es) * 1985-12-27 1994-08-16 Sumitomo Pharma Un metodo para preparar una formulacion de liberacion mantenida.
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
CA1257199A (en) * 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
US5110604A (en) * 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5024841A (en) * 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4948540A (en) * 1988-08-01 1990-08-14 Semex Medical, Inc. Method of preparing collagen dressing sheet material
DE3835237C1 (es) * 1988-10-15 1989-12-28 B. Braun Melsungen Ag, 3508 Melsungen, De
US4992220A (en) * 1989-06-23 1991-02-12 Neri Michael A Method for producing biodegradable packaging material
AT393956B (de) * 1989-10-20 1992-01-10 Loidl Rudolf Vorrichtung zum aufbewahren und zeitpunktgerechten einnehmen von medikamenten
US5425769A (en) * 1990-04-23 1995-06-20 Snyders, Jr.; Robert V. Composition of material for osseous repair
IT1255298B (it) * 1992-01-27 1995-10-26 Xenocollagene e derivati
GB9206508D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Biopolymer composites
US5660857A (en) * 1993-03-22 1997-08-26 Johnson & Johnson Medical Inc. Biopolymer composites
DE4414755C2 (de) * 1994-04-27 2000-11-16 Lohmann Therapie Syst Lts Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung
US7883693B2 (en) * 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
PT876165E (pt) * 1995-12-18 2006-10-31 Angiotech Biomaterials Corp Composicoes de polimeros reticulados e processos para a sua utilizacao
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
CA2251475C (en) * 1996-04-04 2006-09-05 Immuno Aktiengesellschaft Hemostatic sponge based on collagen
US6177609B1 (en) 1997-03-10 2001-01-23 Meadox Medicals, Inc. Self-aggregating protein compositions and use as sealants
US7241309B2 (en) 1999-04-15 2007-07-10 Scimed Life Systems, Inc. Self-aggregating protein compositions and use as sealants
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
US20040219214A1 (en) * 2002-12-30 2004-11-04 Angiotech International Ag Tissue reactive compounds and compositions and uses thereof
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
DE602004021022D1 (de) * 2003-10-28 2009-06-18 Medtronic Inc Verfahren zur herstellung von vernetzten materialien und bioprothetischen vorrichtungen
KR100974733B1 (ko) 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
WO2006028415A1 (en) * 2004-09-09 2006-03-16 Agency For Science, Technology And Research Process for isolating biomaterial from tissue and an isolated biomaterial extract prepared therefrom
WO2006034128A2 (en) 2004-09-17 2006-03-30 Angiotech Biomaterials Corporation Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
US20070224251A1 (en) * 2006-03-22 2007-09-27 Masao Tanihara Hemostatic material
EP2152743A2 (en) * 2007-05-23 2010-02-17 Allergan, Inc. Cross-linked collagen and uses thereof
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
KR101577471B1 (ko) 2007-11-16 2015-12-14 알러간, 인코포레이티드 자색반병의 치료를 위한 조성물 및 방법
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
WO2010115081A2 (en) * 2009-04-02 2010-10-07 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
CA2792729C (en) * 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8435541B2 (en) 2010-09-02 2013-05-07 Bath & Body Works Brand Management, Inc. Topical compositions for inhibiting matrix metalloproteases and providing antioxidative activities
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
KR102015676B1 (ko) 2011-06-03 2019-10-21 알러간, 인코포레이티드 항산화제를 포함하는 피부 충전제 조성물
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
NO2802624T3 (es) * 2012-01-09 2017-12-30
CN103505759B (zh) * 2013-07-04 2015-04-29 四川大学 一种用环氧季铵盐对胶原进行改性的方法
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2934447A (en) * 1957-10-22 1960-04-26 United Shoe Machinery Corp Collagen fiber masses and methods of making the same
US3034852A (en) * 1960-01-26 1962-05-15 Japan Leather Mfg Co Ltd Solubilization of insoluble collagen fibers and reconstitution thereof
US3157524A (en) * 1960-10-25 1964-11-17 Ethicon Inc Preparation of collagen sponge
GB1195061A (en) * 1966-05-27 1970-06-17 Fmc Corp Coated Structures and Methods of Forming Them.
JPS4615033B1 (es) * 1967-09-16 1971-04-22
US3514518A (en) * 1967-12-19 1970-05-26 Pierre Charier Vadrot Process for preparation of gelatinous material from animal collagen
US3742955A (en) * 1970-09-29 1973-07-03 Fmc Corp Fibrous collagen derived product having hemostatic and wound binding properties
GB1347582A (en) * 1972-02-02 1974-02-27 Interprinderea Flacara Rosie Collagenic medicinal dressing
DE2462222A1 (de) * 1974-02-02 1976-05-06 Trommsdorff Fa H Loesliches, natives human-kollagen, dessen nicht-helikale peptide teilweise oder vollstaendig abgetrennt sind
US3939831A (en) * 1974-03-04 1976-02-24 Intreprinderea Flacara Rosie Process for preparing medicinal dressings
JPS597684B2 (ja) * 1976-05-20 1984-02-20 明治製菓株式会社 コラ−ゲンを用いた眼用徐放性制御医薬剤
US4066083A (en) * 1976-06-03 1978-01-03 Pentapharm A.G. Sterile surgical collagen product
US4097234A (en) * 1976-12-10 1978-06-27 Nippi, Incorporated Method for preparing dispersion of collagen fiber

Also Published As

Publication number Publication date
GB2116978B (en) 1984-02-22
GB8302017D0 (en) 1983-02-23
GB2058084B (en) 1983-07-27
FR2464962B1 (es) 1983-07-22
CH647947A5 (fr) 1985-02-28
JPS5695195A (en) 1981-08-01
DE3034273A1 (de) 1981-04-02
CA1147726A (en) 1983-06-07
JPS642120B2 (es) 1989-01-13
GB2058084A (en) 1981-04-08
DE3034273C2 (es) 1990-03-22
IT1128187B (it) 1986-05-28
IT8049654A0 (it) 1980-09-11
ES494963A0 (es) 1981-09-01
GB2116978A (en) 1983-10-05
FR2464962A1 (fr) 1981-03-20
US4279812A (en) 1981-07-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203