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ES8101613A1 - Un procedimiento para la preparacion de fosfato de p-aletaminofenilo. - Google Patents

Un procedimiento para la preparacion de fosfato de p-aletaminofenilo.

Info

Publication number
ES8101613A1
ES8101613A1 ES486948A ES486948A ES8101613A1 ES 8101613 A1 ES8101613 A1 ES 8101613A1 ES 486948 A ES486948 A ES 486948A ES 486948 A ES486948 A ES 486948A ES 8101613 A1 ES8101613 A1 ES 8101613A1
Authority
ES
Spain
Prior art keywords
acetaminophenyl
antipyretics
analgesics
phosphate salts
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486948A
Other languages
English (en)
Other versions
ES486948A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BOTTU
Original Assignee
BOTTU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BOTTU filed Critical BOTTU
Publication of ES486948A0 publication Critical patent/ES486948A0/es
Publication of ES8101613A1 publication Critical patent/ES8101613A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE FOSFATO DE P-ACETAMINOFENILO. CONSTA DE LAS SIGUIENTES ETAPAS: 1) REDUCCION DE LA SAL DISODICA DEL ESTER FOSFORICO DEL P-NITROFENOL PARA OBTENER EL DERIVADO P-AMINO, SOBRE UN CATALIZADOR DE PALADIO EN CARBON. 2) ACETILACION DE LA FUNCION AMINA CON ANHIDRIDO ACETICO. 3) OPCIONALMENTE, REACCION DE FOSFATO DE P-ACETAMINOFENILO OBTENIDO EN LA ETAPA ANTERIOR CON UNA AMINA, TAL COMO GLICINA, LISINA O ADENOSINA. OBTENCION DE ANALGESICOS Y ANTIPIRETICOS.
ES486948A 1978-12-15 1979-12-14 Un procedimiento para la preparacion de fosfato de p-aletaminofenilo. Expired ES8101613A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7835429A FR2444043A1 (fr) 1978-12-15 1978-12-15 Nouveau derive du paracetamol, son procede de preparation et son utilisation en therapeutique

Publications (2)

Publication Number Publication Date
ES486948A0 ES486948A0 (es) 1980-12-16
ES8101613A1 true ES8101613A1 (es) 1980-12-16

Family

ID=9216203

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486948A Expired ES8101613A1 (es) 1978-12-15 1979-12-14 Un procedimiento para la preparacion de fosfato de p-aletaminofenilo.

Country Status (11)

Country Link
US (1) US4322410A (es)
JP (1) JPS5583792A (es)
BE (1) BE880615A (es)
CA (1) CA1131627A (es)
CH (1) CH642378A5 (es)
DE (1) DE2949669A1 (es)
ES (1) ES8101613A1 (es)
FR (1) FR2444043A1 (es)
GB (1) GB2037772B (es)
IT (1) IT1126572B (es)
NL (1) NL7908988A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4591582A (en) * 1984-04-17 1986-05-27 Research Corporation Organophosphorus compounds useful as anticonvulsant agents
IT1213182B (it) * 1984-06-25 1989-12-14 Simes Derivati di composti a struttura catecolamminica.
US4710566A (en) * 1984-12-27 1987-12-01 Yale University Purification of the messenger RNA cap-binding protein
GB2289535B (en) * 1994-05-13 1998-08-05 Cambridge Life Sciences Paracetamol phosphate for immunoassays
US5661138A (en) * 1996-10-03 1997-08-26 Clarion Pharmaceutical, Inc. (o-Acyl-p-N-acylamino-phenyl)-O-phosphoethanolamines
RU2010151952A (ru) 2008-05-20 2012-06-27 Ньюроджесэкс, Инк. (Us) Водорастворимые аналоги ацетаминофена
EP2291084A4 (en) 2008-05-20 2012-04-25 Neurogesx Inc CARBONATE PRODRUGS AND METHOD FOR THEIR USE
JP6029670B2 (ja) 2011-09-22 2016-11-24 アコーダ セラピューティクス、インク． アセトアミノフェンコンジュゲートおよびその組成物ならびにその使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE269205C (es) * 1911-08-02
US2023551A (en) * 1933-06-28 1935-12-10 Rosenzweig Salo Guaiacol compounds and the production thereof
US3032555A (en) * 1955-11-03 1962-05-01 Boots Pure Drug Co Ltd Dichloroacetanilide esters and the manufacture thereof
US3107262A (en) * 1962-01-25 1963-10-15 Leo K Rochen Alkyl acid phosphate salts

Also Published As

Publication number Publication date
US4322410A (en) 1982-03-30
DE2949669A1 (de) 1980-07-03
CA1131627A (en) 1982-09-14
IT1126572B (it) 1986-05-21
ES486948A0 (es) 1980-12-16
JPS5583792A (en) 1980-06-24
FR2444043A1 (fr) 1980-07-11
GB2037772B (en) 1983-05-11
NL7908988A (nl) 1980-06-17
FR2444043B1 (es) 1981-07-24
IT7928015A0 (it) 1979-12-07
CH642378A5 (fr) 1984-04-13
GB2037772A (en) 1980-07-16
BE880615A (fr) 1980-06-16

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