ES557552A0 - Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas - Google Patents

Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Info

Publication number: ES557552A0
Authority: ES; Spain
Prior art keywords: onas; quinolin; imidazo; dihydro; procedure
Prior art date: 1985-04-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES557552A

Other languages

English (en)

Other versions

ES8802521A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1987-05-14

Publication date

1988-07-16

1987-05-14 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1988-07-16 Publication of ES8802521A1 publication Critical patent/ES8802521A1/es

1988-07-16 Publication of ES557552A0 publication Critical patent/ES557552A0/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ES557552A 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas Expired ES8802521A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US72686985A	1985-04-25	1985-04-25
US06/832,212 US4668686A (en)	1985-04-25	1986-02-26	Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (2)

Publication Number	Publication Date
ES8802521A1 ES8802521A1 (es)	1988-07-16
ES557552A0 true ES557552A0 (es)	1988-07-16

Family

ID=27111398

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES554336A Expired ES8708229A1 (es)	1985-04-25	1986-04-24	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.
ES557551A Expired ES8801829A1 (es)	1985-04-25	1987-05-14	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas
ES557552A Expired ES8802521A1 (es)	1985-04-25	1987-05-14	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES554336A Expired ES8708229A1 (es)	1985-04-25	1986-04-24	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.
ES557551A Expired ES8801829A1 (es)	1985-04-25	1987-05-14	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Country Status (32)

Country	Link
US (1)	US4668686A (es)
KR (1)	KR940000828B1 (es)
CN (1)	CN1016175B (es)
AT (1)	AT390257B (es)
AU (1)	AU592983B2 (es)
BE (1)	BE904671A (es)
CA (1)	CA1298836C (es)
CH (1)	CH675722A5 (es)
CY (1)	CY1641A (es)
DE (1)	DE3614132A1 (es)
DK (3)	DK164868C (es)
EG (1)	EG18104A (es)
ES (3)	ES8708229A1 (es)
FI (1)	FI83316C (es)
FR (1)	FR2581065B1 (es)
GB (1)	GB2174987B (es)
GR (1)	GR861086B (es)
HK (1)	HK64492A (es)
HU (1)	HU195813B (es)
IL (1)	IL78581A0 (es)
IT (1)	IT1215651B (es)
LU (1)	LU86406A1 (es)
MY (1)	MY102086A (es)
NL (1)	NL8601053A (es)
NO (1)	NO163406C (es)
NZ (1)	NZ215885A (es)
OA (1)	OA08242A (es)
PT (1)	PT82460B (es)
SE (1)	SE461468B (es)
SG (1)	SG29092G (es)
SU (3)	SU1450746A3 (es)
YU (1)	YU46054B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4775674A (en) *	1986-05-23	1988-10-04	Bristol-Myers Company	Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) *	1986-07-08	1987-10-20	Bristol-Myers Company	7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4803210A (en) *	1987-05-29	1989-02-07	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic oxazolones
US4743607A (en) *	1987-05-29	1988-05-10	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic imidazolones
US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) *	1990-11-10	1996-10-02	Daimler Benz Ag	Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5196428A (en) *	1992-04-03	1993-03-23	Bristol-Myers Squibb Company	Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5158958A (en) *	1992-04-03	1992-10-27	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5348960A (en) *	1992-04-03	1994-09-20	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5208237A (en) *	1992-04-03	1993-05-04	Bristol-Meyers Squibb Company	7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5552267A (en) *	1992-04-03	1996-09-03	The Trustees Of Columbia University In The City Of New York	Solution for prolonged organ preservation
AR045260A1 (es)	2003-08-12	2005-10-19	3M Innovative Properties Co	Compuestos que contienen imidazo-oxima sustituidos
RU2006105101A (ru)	2003-08-27	2007-10-10	3М Инновейтив Пропертиз Компани (US)	Арилокси и арилалкиленокси замещенные имидазохинолины
US20050054665A1 (en)	2003-09-05	2005-03-10	3M Innovative Properties Company	Treatment for CD5+ B cell lymphoma
BRPI0414856A (pt)	2003-10-03	2006-11-21	3M Innovative Properties Co	imidazoquinolinas alcóxi-substituìdas
US7544697B2 (en)	2003-10-03	2009-06-09	Coley Pharmaceutical Group, Inc.	Pyrazolopyridines and analogs thereof
JP2007511535A (ja) *	2003-11-14	2007-05-10	スリーエムイノベイティブプロパティズカンパニー	ヒドロキシルアミン置換イミダゾ環化合物
AU2004291101A1 (en)	2003-11-14	2005-06-02	3M Innovative Properties Company	Oxime substituted imidazo ring compounds
EP1687307B1 (en)	2003-11-25	2016-01-06	3M Innovative Properties Company	Substituted imidazo ring systems and methods
EP1701955A1 (en)	2003-12-29	2006-09-20	3M Innovative Properties Company	Arylalkenyl and arylalkynyl substituted imidazoquinolines
CA2551399A1 (en)	2003-12-30	2005-07-21	3M Innovative Properties Company	Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
US8697873B2 (en)	2004-03-24	2014-04-15	3M Innovative Properties Company	Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en)	2004-06-15	2011-09-13	3M Innovative Properties Company	Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en)	2004-06-18	2006-04-13	3M Innovative Properties Company	Aryl substituted imidazonaphthyridines
US8026366B2 (en)	2004-06-18	2011-09-27	3M Innovative Properties Company	Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7915281B2 (en)	2004-06-18	2011-03-29	3M Innovative Properties Company	Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
ES2392648T3 (es)	2004-12-30	2012-12-12	3M Innovative Properties Company	Compuestos quirales sustituidos que contienen un núcleo 1,2-imidazo-4,5-c condensado
CA2592904C (en)	2004-12-30	2015-04-07	3M Innovative Properties Company	Chiral fused [1,2]imidazo[4,5-c] ring compounds
US9248127B2 (en)	2005-02-04	2016-02-02	3M Innovative Properties Company	Aqueous gel formulations containing immune response modifiers
WO2006086634A2 (en)	2005-02-11	2006-08-17	Coley Pharmaceutical Group, Inc.	Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
AU2006232377A1 (en)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Pyrazolopyridine-1,4-diamines and analogs thereof
AU2006232375A1 (en)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7906506B2 (en)	2006-07-12	2011-03-15	3M Innovative Properties Company	Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US7598248B2 (en)	2006-08-02	2009-10-06	Cytokinetics, Inc.	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols, compositions thereof, and methods for their use
US8227603B2 (en)	2006-08-01	2012-07-24	Cytokinetics, Inc.	Modulating skeletal muscle
US8299248B2 (en)	2006-08-02	2012-10-30	Cytokinetics, Incorporated	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
US7851484B2 (en)	2007-03-30	2010-12-14	Cytokinetics, Inc.	Certain chemical entities, compositions, and methods
IN2014DN00200A (es)	2011-07-13	2015-06-05	Cytokinetics Inc
WO2024149378A1 (zh) *	2023-01-13	2024-07-18	上海超阳药业有限公司	喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

1986
- 1986-02-26 US US06/832,212 patent/US4668686A/en not_active Expired - Fee Related
- 1986-03-26 CA CA000505136A patent/CA1298836C/en not_active Expired - Fee Related
- 1986-04-18 NZ NZ215885A patent/NZ215885A/xx unknown
- 1986-04-21 AU AU56413/86A patent/AU592983B2/en not_active Ceased
- 1986-04-22 FI FI861684A patent/FI83316C/fi not_active IP Right Cessation
- 1986-04-22 IL IL78581A patent/IL78581A0/xx not_active IP Right Cessation
- 1986-04-23 EG EG237/86A patent/EG18104A/xx active
- 1986-04-23 CN CN86102747A patent/CN1016175B/zh not_active Expired
- 1986-04-24 CH CH1679/86A patent/CH675722A5/de not_active IP Right Cessation
- 1986-04-24 GB GB8610037A patent/GB2174987B/en not_active Expired
- 1986-04-24 NL NL8601053A patent/NL8601053A/xx not_active Application Discontinuation
- 1986-04-24 PT PT82460A patent/PT82460B/pt not_active IP Right Cessation
- 1986-04-24 IT IT8620206A patent/IT1215651B/it active
- 1986-04-24 GR GR861086A patent/GR861086B/el unknown
- 1986-04-24 DK DK190986A patent/DK164868C/da not_active IP Right Cessation
- 1986-04-24 FR FR868605966A patent/FR2581065B1/fr not_active Expired - Fee Related
- 1986-04-24 ES ES554336A patent/ES8708229A1/es not_active Expired
- 1986-04-24 SE SE8601907A patent/SE461468B/sv not_active IP Right Cessation
- 1986-04-24 LU LU86406A patent/LU86406A1/fr unknown
- 1986-04-24 NO NO861617A patent/NO163406C/no unknown
- 1986-04-24 BE BE0/216585A patent/BE904671A/fr not_active IP Right Cessation
- 1986-04-24 SU SU864027355A patent/SU1450746A3/ru active
- 1986-04-25 OA OA58845A patent/OA08242A/xx unknown
- 1986-04-25 DE DE19863614132 patent/DE3614132A1/de not_active Ceased
- 1986-04-25 AT AT0112186A patent/AT390257B/de not_active IP Right Cessation
- 1986-04-25 HU HU861723A patent/HU195813B/hu not_active IP Right Cessation
- 1986-04-25 KR KR1019860003204A patent/KR940000828B1/ko not_active Expired - Lifetime
1987
- 1987-02-27 SU SU874202071A patent/SU1470192A3/ru active
- 1987-05-14 ES ES557551A patent/ES8801829A1/es not_active Expired
- 1987-05-14 ES ES557552A patent/ES8802521A1/es not_active Expired
- 1987-06-23 YU YU116787A patent/YU46054B/sh unknown
- 1987-09-25 SU SU874203391A patent/SU1560056A3/ru active
- 1987-09-29 MY MYPI87002266A patent/MY102086A/en unknown
1991
- 1991-04-30 DK DK080291A patent/DK165248C/da not_active IP Right Cessation
- 1991-05-01 DK DK081091A patent/DK165249C/da not_active IP Right Cessation
1992
- 1992-03-10 SG SG290/92A patent/SG29092G/en unknown
- 1992-08-27 HK HK644/92A patent/HK64492A/xx unknown
- 1992-11-06 CY CY1641A patent/CY1641A/en unknown

Also Published As

Publication number	Publication date
NO861617L (no)	1986-10-27
GB2174987B (en)	1989-08-02
KR940000828B1 (ko)	1994-02-02
NO163406C (no)	1990-05-23
CN1016175B (zh)	1992-04-08
DK165249B (da)	1992-10-26
DK164868B (da)	1992-08-31
NZ215885A (en)	1989-04-26
DK165248C (da)	1993-03-22
DK81091A (da)	1991-05-01
HK64492A (en)	1992-09-04
LU86406A1 (fr)	1986-11-05
CN86102747A (zh)	1987-02-04
SU1470192A3 (ru)	1989-03-30
AU592983B2 (en)	1990-02-01
HU195813B (en)	1988-07-28
FR2581065A1 (fr)	1986-10-31
SU1560056A3 (ru)	1990-04-23
CH675722A5 (es)	1990-10-31
YU46054B (sh)	1992-12-21
DK164868C (da)	1993-01-11
DK190986D0 (da)	1986-04-24
AU5641386A (en)	1986-10-30
CA1298836C (en)	1992-04-14
IT8620206A0 (it)	1986-04-24
ES8802521A1 (es)	1988-07-16
OA08242A (en)	1987-10-30
SG29092G (en)	1992-05-15
GB8610037D0 (en)	1986-05-29
FI83316B (fi)	1991-03-15
IL78581A0 (en)	1986-08-31
DK80291D0 (da)	1991-04-30
DK165249C (da)	1993-03-22
ES8801829A1 (es)	1988-02-16
SE8601907D0 (sv)	1986-04-24
CY1641A (en)	1992-11-06
ATA112186A (de)	1989-09-15
ES8708229A1 (es)	1987-10-01
NL8601053A (nl)	1986-11-17
ES554336A0 (es)	1987-10-01
DE3614132A1 (de)	1986-11-27
FI83316C (fi)	1991-06-25
GR861086B (en)	1986-09-01
DK80291A (da)	1991-04-30
US4668686A (en)	1987-05-26
DK190986A (da)	1986-10-26
SU1450746A3 (ru)	1989-01-07
AT390257B (de)	1990-04-10
DK81091D0 (da)	1991-05-01
NO163406B (no)	1990-02-12
BE904671A (fr)	1986-10-24
SE461468B (sv)	1990-02-19
IT1215651B (it)	1990-02-22
FI861684L (fi)	1986-10-26
EG18104A (en)	1992-09-30
HUT42089A (en)	1987-06-29
FR2581065B1 (fr)	1990-02-02
FI861684A0 (fi)	1986-04-22
YU116787A (en)	1988-04-30
MY102086A (en)	1992-03-31
PT82460A (en)	1986-05-01
GB2174987A (en)	1986-11-19
PT82460B (pt)	1988-11-30
SE8601907L (sv)	1986-10-26
ES557551A0 (es)	1988-02-16
KR860008177A (ko)	1986-11-12
DK165248B (da)	1992-10-26

Publication	Publication Date	Title
ES557551A0 (es)	1988-02-16	Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas
ES551249A0 (es)	1987-11-01	Un procedimiento para la preparacion de peptidilaminodioles.
ES517193A0 (es)	1983-12-01	Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
ES555834A0 (es)	1988-02-16	Un procedimiento para la preparacion de nuevas piranopiridinas.
ES556550A0 (es)	1987-12-16	Un procedimiento para la preparacion de androsta -1-4-dien-3,17-dionas.
ES554405A0 (es)	1987-09-01	Un procedimiento para la preparacion de derivados de aza-indol.
ES553044A0 (es)	1987-05-01	Un procedimiento para la preparacion de nuevos derivados de fenoxialquilaminopirimidina.
ES556738A0 (es)	1988-04-01	Un procedimiento para la preparacion de nuevos piridazinaminas.
ES554983A0 (es)	1987-11-01	Un procedimiento para la preparacion de silileteres.
ES552189A0 (es)	1987-04-16	Un procedimiento para la preparacion de derivados de piridimilmidazolidiona.
ES555369A0 (es)	1987-11-16	Un procedimiento para la preparacion de un polialquenoilisocianato.
ES552032A0 (es)	1987-06-01	Un procedimiento para preparar derivados de 1,8-naftiridina
ES553283A0 (es)	1991-04-16	Un procedimiento para la preparacion de 2-amino-6-cloropurina.
ES557828A0 (es)	1990-02-16	Un procedimiento para preparar derivados de ciclopentil-eter.
ES555723A0 (es)	1987-09-16	Un procedimiento para la preparacion de tetrahidroimidazoquinazolinonas.
ES552241A0 (es)	1988-03-01	Un procedimiento para la preparacion de nuevos derivados de pirazolopiridinas.
ES545929A0 (es)	1986-02-01	Un procedimiento para preparar derivados de imidazo(1,2-a) quinoleinas
ES556208A0 (es)	1988-02-16	Un procedimiento para la preparacion de benzimidazoles.
ES555497A0 (es)	1988-02-16	Un procedimiento para la preparacion de (e)-3-metil-5(2,2,3-trimetilciclopent -3-evo-1-ilo) pent-4-eno-2-ol
ES553718A0 (es)	1988-11-16	Procedimiento para la obtencion de un esmalte en polvo, aplicable electrodomesticamente
ES556768A0 (es)	1987-12-16	Un procedimiento para la preparacion de aminoalquil secocantinas.
ES555670A0 (es)	1987-08-16	Un procedimiento para la preparacion de hexahidroarilquinolizinas sustituidas.
ES555109A0 (es)	1987-08-16	Un procedimiento para la preparacion de nuevos derivados de propanodiona.
ES556807A0 (es)	1988-04-16	Un procedimiento para la preparacion de nuevos 11-metileno-esteroides.
ES551041A0 (es)	1987-05-16	Un procedimiento para preparar (1,2,4-oxadiazol-3-il)-arilmetanonas

Legal Events

Date	Code	Title	Description
1997-06-16	FD1A	Patent lapsed	Effective date: 19970519