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ES2667011T3 - Monoacilgliceroles sn-2 y malabsorción lipídica - Google Patents

Monoacilgliceroles sn-2 y malabsorción lipídica Download PDF

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Publication number
ES2667011T3
ES2667011T3 ES10168420.7T ES10168420T ES2667011T3 ES 2667011 T3 ES2667011 T3 ES 2667011T3 ES 10168420 T ES10168420 T ES 10168420T ES 2667011 T3 ES2667011 T3 ES 2667011T3
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ES
Spain
Prior art keywords
monoacylglycerols
positions
lipid malabsorption
protective
malabsorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10168420.7T
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English (en)
Inventor
Bruce Bistrian
Frédéric DESTAILLATS
Cristina Cruz-Hernandez
Fabiola Dionisi
Isabelle Masserey-Elmelegy
Manuel Oliveira
Julie Céline Moulin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nestec SA
Beth Israel Deaconess Medical Center Inc
Original Assignee
Nestec SA
Beth Israel Deaconess Medical Center Inc
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Filing date
Publication date
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Application granted granted Critical
Publication of ES2667011T3 publication Critical patent/ES2667011T3/es
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
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  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
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  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)

Abstract

Composición que comprende un derivado monoacilglicerol sn-2, en la que las posiciones sn-1 y sn-3 se encuentran bloqueadas por grupos protectores, en la que el grupo acilo es un ácido graso que presenta propiedades antiinflamatorias y en la que el grupo protector es la vainillina, que establece puentes entre los grupos hidroxilo en las posiciones sn-1 y sn-3.

Description

imagen1
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Claims (1)

  1. imagen1
ES10168420.7T 2010-07-05 2010-07-05 Monoacilgliceroles sn-2 y malabsorción lipídica Active ES2667011T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10168420.7A EP2409695B1 (en) 2010-07-05 2010-07-05 Sn-2-monoacylglycerols and lipid malabsorption

Publications (1)

Publication Number Publication Date
ES2667011T3 true ES2667011T3 (es) 2018-05-09

Family

ID=42669828

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10168420.7T Active ES2667011T3 (es) 2010-07-05 2010-07-05 Monoacilgliceroles sn-2 y malabsorción lipídica
ES11729629T Active ES2769296T3 (es) 2010-07-05 2011-07-05 Monoacilgliceroles sn-2 y malabsorción de lípidos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES11729629T Active ES2769296T3 (es) 2010-07-05 2011-07-05 Monoacilgliceroles sn-2 y malabsorción de lípidos

Country Status (8)

Country Link
US (5) US20130109753A1 (es)
EP (2) EP2409695B1 (es)
JP (1) JP6157349B2 (es)
CN (1) CN103002889B (es)
DK (2) DK2409695T3 (es)
ES (2) ES2667011T3 (es)
TR (1) TR201808471T4 (es)
WO (1) WO2012004234A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2498628B1 (en) * 2010-12-29 2014-04-30 Abbott Laboratories Products for decreasing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome in an infant, toddler, or child
EP2508180A1 (en) * 2011-04-04 2012-10-10 Nestec S.A. Sn-1(3) Monoacylglycerides and lipid absorption
JP6456302B2 (ja) 2013-02-11 2019-01-23 フィリップス ライティング ホールディング ビー ヴィ フェノキシ置換ペリレン−３，４，９，１０−テトラカルボン酸ジイミド有機赤色放出体及びそれを用いた発光デバイス
JP6081024B2 (ja) * 2013-08-19 2017-02-15 エンジーケム ライフサイエンシーズ コーポレーションＥｎｚｙｃｈｅｍ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ モノアセチルジアシルグリセロール化合物を有効成分として含有する関節リウマチの予防または治療用組成物
ES2902679T3 (es) * 2013-08-19 2022-03-29 Enzychem Lifesciences Corp Composición que contiene compuesto de monoacetildiacilglicerol como principio activo para prevenir o tratar el asma
AU2014315877B2 (en) * 2013-09-03 2017-03-23 Enzychem Lifesciences Corporation Composition containing monoacetyldiacylglycerol compound as active ingredient for preventing or treating atopic dermatitis
US20160263072A1 (en) * 2013-10-28 2016-09-15 Nestec S.A. Monoacylglycerols and fat-soluble nutrients for use in the treatment of malabsorption having a non-mechanical basis
AU2014343901A1 (en) * 2013-10-28 2016-03-17 Nestec S.A. Monoacylglycerols and fat-soluble nutrients for use in the treatment of maldigestion
AU2015340903A1 (en) * 2014-10-27 2017-04-06 Société des Produits Nestlé S.A. Nutritional compositions comprising sn-1 (3) monoacylglycerols for use in the treatment of malabsorption or maldigestion in infants or young children
WO2017003992A1 (en) 2015-07-02 2017-01-05 Stepan Company Method for preparing 2-monoacylglycerides

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59190948A (ja) * 1983-04-14 1984-10-29 ルセル―ユクラフ 新規なトリグリセリド、その製造法、食餌療法及び治療法への使用並びにそれを含む組成物
JPS6387988A (ja) * 1986-10-01 1988-04-19 Nisshin Oil Mills Ltd:The 消化吸収性の良い油脂
JPH04316539A (ja) * 1991-05-23 1992-11-06 Roussel Uclaf 新規なトリグリセリド、その製造法、食餌療法及び治療法への使用並びにそれを含む組成物
EP1090636A1 (en) * 1999-09-13 2001-04-11 Société des Produits Nestlé S.A. High lipid diet
FR2833606B1 (fr) * 2001-12-19 2004-02-13 Inst Francais Du Petrole Compositions de carburants diesel contenant des carbonates d'acetals de glycerol
GB0311081D0 (en) * 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
JP2007502805A (ja) * 2003-08-18 2007-02-15 ビーティージー・インターナショナル・リミテッド 神経変性状態の処置
CA2551119C (en) * 2004-01-16 2013-02-12 Fuji Oil Company Limited Lipase inhibitor
JP2005225863A (ja) * 2004-01-16 2005-08-25 Fuji Oil Co Ltd リパーゼ阻害剤
GB0504362D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
EP1774973A1 (en) * 2005-10-12 2007-04-18 Nutricia N.V. Leucine rich composition
JP2009084230A (ja) * 2007-10-01 2009-04-23 Idemitsu Kosan Co Ltd 炎症抑制剤

Also Published As

Publication number Publication date
JP2013530999A (ja) 2013-08-01
DK2590644T3 (da) 2020-02-17
US9687462B2 (en) 2017-06-27
US20170296507A1 (en) 2017-10-19
EP2590644B1 (en) 2020-01-01
CN103002889A (zh) 2013-03-27
EP2409695A1 (en) 2012-01-25
US20140142169A1 (en) 2014-05-22
JP6157349B2 (ja) 2017-07-05
US10039742B2 (en) 2018-08-07
CN103002889B (zh) 2017-03-29
US20150224079A1 (en) 2015-08-13
TR201808471T4 (tr) 2018-07-23
US20170056362A1 (en) 2017-03-02
US9522132B2 (en) 2016-12-20
EP2590644A1 (en) 2013-05-15
US20130109753A1 (en) 2013-05-02
US9034917B2 (en) 2015-05-19
WO2012004234A1 (en) 2012-01-12
ES2769296T3 (es) 2020-06-25
EP2409695B1 (en) 2018-03-21
DK2409695T3 (en) 2018-05-28

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