ES2514665T3 - Derivados de sulfuro de difenilo y medicamentos que contienen los mismos como principio activo - Google Patents

Derivados de sulfuro de difenilo y medicamentos que contienen los mismos como principio activo Download PDF

Info

Publication number: ES2514665T3
Authority: ES; Spain
Prior art keywords: group; carbon atoms; formula; amino; reference example
Prior art date: 2009-07-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

ES10796915.6T

Other languages

English (en)

Spanish (es)

Inventor

Yasushi Kohno

Kiyoshi Fujii

Momoko Taru

Keita Miyoshi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kyorin Pharmaceutical Co Ltd

Original Assignee

Kyorin Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-09

Filing date

2010-07-08

Publication date

2014-10-28

2010-07-08 Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd

2014-10-28 Application granted granted Critical

2014-10-28 Publication of ES2514665T3 publication Critical patent/ES2514665T3/es

Status Active legal-status Critical Current

2030-07-08 Anticipated expiration legal-status Critical

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pulmonology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Diabetes (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES10796915.6T 2009-07-09 2010-07-08 Derivados de sulfuro de difenilo y medicamentos que contienen los mismos como principio activo Active ES2514665T3 (es)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
JP2009162289		2009-07-09
JP2009162289		2009-07-09
JP2010112138		2010-05-14
JP2010112138		2010-05-14
PCT/JP2010/004453 WO2011004604A1 (fr)	2009-07-09	2010-07-08	Dérivés de sulfure de diphényle et médicaments les contenant comme principe actif

Publications (1)

Publication Number	Publication Date
ES2514665T3 true ES2514665T3 (es)	2014-10-28

Family

ID=43429031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES10796915.6T Active ES2514665T3 (es)	2009-07-09	2010-07-08	Derivados de sulfuro de difenilo y medicamentos que contienen los mismos como principio activo

Country Status (20)

Country	Link
US (1)	US8569270B2 (fr)
EP (1)	EP2452944B1 (fr)
JP (1)	JP5616342B2 (fr)
KR (1)	KR20120089234A (fr)
CN (1)	CN102471355B (fr)
AU (1)	AU2010269668B2 (fr)
BR (1)	BR112012000320A2 (fr)
CA (1)	CA2764126A1 (fr)
DK (1)	DK2452944T3 (fr)
ES (1)	ES2514665T3 (fr)
HK (1)	HK1171234A1 (fr)
HR (1)	HRP20141065T1 (fr)
MX (1)	MX2011013182A (fr)
NZ (1)	NZ596605A (fr)
PL (1)	PL2452944T3 (fr)
PT (1)	PT2452944E (fr)
SG (1)	SG176573A1 (fr)
SI (1)	SI2452944T1 (fr)
WO (1)	WO2011004604A1 (fr)
ZA (1)	ZA201108459B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI519539B (zh) *	2010-12-21	2016-02-01	Kyorin Seiyaku Kk	Diphenyl sulfide derivatives and pharmaceuticals as an active ingredient thereof
CN102863345A (zh) *	2011-07-06	2013-01-09	中国医学科学院药物研究所	胺基丙二醇类衍生物、其制备方法和其药物组合物与用途
WO2015194157A1 (fr) *	2014-06-16	2015-12-23	杏林製薬株式会社	Procédé de fabrication et intermédiaire de fabrication de dérivé diphénylsulfure
CN110357773A (zh) *	2019-07-08	2019-10-22	南通嘉禾化工有限公司	3-氯-4-羟基苯甲酸的合成
CN113754613B (zh) *	2021-09-27	2023-06-30	北京工商大学	一种4-烯醇的苯硫基环醚化方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003020313A1 (fr)	2001-09-04	2003-03-13	Ono Pharmaceutical Co., Ltd.	Medicaments contre les maladies respiratoires renfermant un agent de regulation du recepteur de la sphingosine-1-phosphate
EP1431275B1 (fr)	2001-09-27	2010-04-07	Kyorin Pharmaceutical Co., Ltd.	Derive d'ether de diaryle, son sel d'addition et son immunosuppresseur
CA2461212C (fr)	2001-09-27	2010-08-17	Kyorin Pharmaceutical Co., Ltd.	Derive de sulfure de diaryle, sels correspondant et agents immunosuppresseur utilisant ces derives
BR0314455A (pt)	2002-09-19	2005-07-26	Kyorin Seiyaku Kk	Derivados de aminoálcool, seus sais e agentes imunosupressores
CA2515574C (fr) *	2003-02-18	2012-03-13	Kyorin Pharmaceutical Co., Ltd.	Derives d'acide aminophosphonique, leurs sels d'addition et des modulateurs de recepteurs s1p
SA04250253B1 (ar)	2003-08-21	2009-11-10	استرازينيكا ايه بي	احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
WO2005044780A1 (fr)	2003-11-10	2005-05-19	Kyorin Pharmaceutical Co., Ltd.	Derive d'acide aminocarboxylique, son sel d'addition et agent de regulation du recepteur s1p
JP2005247691A (ja)	2004-03-01	2005-09-15	Toa Eiyo Ltd	Ｓ１ｐ３受容体拮抗薬
US7888527B2 (en)	2004-12-06	2011-02-15	University Of Virginia Patent Foundation	Aryl amide sphingosine 1-phosphate analogs
WO2007043568A1 (fr)	2005-10-12	2007-04-19	Toa Eiyo Ltd.	Antagoniste du récepteur de s1p3
US20090318389A1 (en) *	2006-08-04	2009-12-24	Praecis Pharmaceuticals Incorporated	Agonists of the sphingosine-1 phosphate receptor
MY152176A (en)	2006-08-08	2014-08-15	Kyorin Seiyaku Kk	Amino phosphate derivative and s1p receptor modulator having same as an active ingredient
JP2008239546A (ja) *	2007-03-27	2008-10-09	Kyorin Pharmaceut Co Ltd	アミノアルコール誘導体及びそれらを有効成分とする免疫抑制剤
JP2010013407A (ja) *	2008-07-04	2010-01-21	Kyorin Pharmaceut Co Ltd	アミノアルコール誘導体
JP2010077053A (ja) *	2008-09-25	2010-04-08	Kyorin Pharmaceut Co Ltd	フェノール誘導体及びそれらを有効成分とする医薬

2010
- 2010-07-08 NZ NZ596605A patent/NZ596605A/xx not_active IP Right Cessation
- 2010-07-08 MX MX2011013182A patent/MX2011013182A/es active IP Right Grant
- 2010-07-08 PL PL10796915T patent/PL2452944T3/pl unknown
- 2010-07-08 AU AU2010269668A patent/AU2010269668B2/en not_active Ceased
- 2010-07-08 JP JP2011521823A patent/JP5616342B2/ja not_active Expired - Fee Related
- 2010-07-08 SG SG2011085511A patent/SG176573A1/en unknown
- 2010-07-08 DK DK10796915.6T patent/DK2452944T3/da active
- 2010-07-08 SI SI201030811T patent/SI2452944T1/sl unknown
- 2010-07-08 CN CN201080030630.3A patent/CN102471355B/zh not_active Expired - Fee Related
- 2010-07-08 WO PCT/JP2010/004453 patent/WO2011004604A1/fr active Application Filing
- 2010-07-08 EP EP10796915.6A patent/EP2452944B1/fr active Active
- 2010-07-08 US US13/382,011 patent/US8569270B2/en active Active
- 2010-07-08 ES ES10796915.6T patent/ES2514665T3/es active Active
- 2010-07-08 BR BR112012000320A patent/BR112012000320A2/pt not_active IP Right Cessation
- 2010-07-08 PT PT107969156T patent/PT2452944E/pt unknown
- 2010-07-08 CA CA2764126A patent/CA2764126A1/fr not_active Abandoned
- 2010-07-08 KR KR1020127003551A patent/KR20120089234A/ko active IP Right Grant
2011
- 2011-11-17 ZA ZA2011/08459A patent/ZA201108459B/en unknown
2012
- 2012-11-21 HK HK12111884.2A patent/HK1171234A1/zh not_active IP Right Cessation
2014
- 2014-11-03 HR HRP20141065AT patent/HRP20141065T1/hr unknown

Also Published As

Publication number	Publication date
HK1171234A1 (zh)	2013-03-22
EP2452944B1 (fr)	2014-09-10
ZA201108459B (en)	2012-07-25
SG176573A1 (en)	2012-01-30
PT2452944E (pt)	2014-10-13
EP2452944A4 (fr)	2013-04-03
JP5616342B2 (ja)	2014-10-29
BR112012000320A2 (pt)	2016-03-22
PL2452944T3 (pl)	2015-03-31
DK2452944T3 (da)	2014-10-27
AU2010269668B2 (en)	2013-12-19
CA2764126A1 (fr)	2011-01-13
SI2452944T1 (sl)	2015-01-30
US20120101068A1 (en)	2012-04-26
WO2011004604A1 (fr)	2011-01-13
CN102471355A (zh)	2012-05-23
JPWO2011004604A1 (ja)	2012-12-20
MX2011013182A (es)	2012-01-31
NZ596605A (en)	2013-09-27
AU2010269668A1 (en)	2011-12-15
US8569270B2 (en)	2013-10-29
EP2452944A1 (fr)	2012-05-16
CN102471355B (zh)	2015-10-07
KR20120089234A (ko)	2012-08-09
HRP20141065T1 (hr)	2015-02-13

Publication	Publication Date	Title
ES2438265T3 (es)	2014-01-16	Derivado del éster del ácido aminofosfórico y modulador del receptor de S1P que lo contiene como principio activo
ES2514665T3 (es)	2014-10-28	Derivados de sulfuro de difenilo y medicamentos que contienen los mismos como principio activo
CN102985432B (zh)	2016-11-02	用于治疗心脏病的amp衍生物
AU2011346254B2 (en)	2016-08-04	Diphenyl sulfide derivative and pharmaceutical product which contains same as active ingredient
JP2011032226A (ja)	2011-02-17	ジフェニルスルフィド誘導体及びそれらを有効成分とする医薬
JP2010077053A (ja)	2010-04-08	フェノール誘導体及びそれらを有効成分とする医薬
JP2012131725A (ja)	2012-07-12	ジフェニルスルフィド誘導体及びそれらを有効成分とする医薬