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ES2143558T3 - Agentes policiclicos antiparasitarios, procedimiento y cepa para su preparacion y su uso. - Google Patents

Agentes policiclicos antiparasitarios, procedimiento y cepa para su preparacion y su uso.

Info

Publication number
ES2143558T3
ES2143558T3 ES94932063T ES94932063T ES2143558T3 ES 2143558 T3 ES2143558 T3 ES 2143558T3 ES 94932063 T ES94932063 T ES 94932063T ES 94932063 T ES94932063 T ES 94932063T ES 2143558 T3 ES2143558 T3 ES 2143558T3
Authority
ES
Spain
Prior art keywords
strain
polyclic
antiparasitic
agents
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94932063T
Other languages
English (en)
Inventor
Anne W Dombrowski
Richard G Endris
Gregory L Helms
Otto D Hensens
John G Ondeyka
Dan A Ostlind
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2143558T3 publication Critical patent/ES2143558T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

SE PRESENTAN NUEVOS COMPUESTOS QUE TIENEN LAS FORMULAS (I-III) QUE SE DERIVAN DE LA FERMENTACION DE UNA CEPA DEL "NODULISPORIUM SP". LOS COMPUESTOS SON AGENTES ECTOPARASITICIDAS, ANTIPARASITARIOS E INSECTICIDAS ALTAMENTE POTENTES.
ES94932063T 1993-11-01 1994-10-27 Agentes policiclicos antiparasitarios, procedimiento y cepa para su preparacion y su uso. Expired - Lifetime ES2143558T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/146,638 US5399582A (en) 1993-11-01 1993-11-01 Antiparasitic agents

Publications (1)

Publication Number Publication Date
ES2143558T3 true ES2143558T3 (es) 2000-05-16

Family

ID=22518283

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94932063T Expired - Lifetime ES2143558T3 (es) 1993-11-01 1994-10-27 Agentes policiclicos antiparasitarios, procedimiento y cepa para su preparacion y su uso.

Country Status (24)

Country Link
US (2) US5399582A (es)
EP (1) EP0726902B1 (es)
JP (1) JP3557212B2 (es)
KR (1) KR100333017B1 (es)
CN (2) CN1046943C (es)
AT (1) ATE188476T1 (es)
AU (1) AU688405B2 (es)
CA (1) CA2174645C (es)
CZ (1) CZ286032B6 (es)
DE (1) DE69422526T2 (es)
DK (1) DK0726902T3 (es)
ES (1) ES2143558T3 (es)
FI (2) FI110871B (es)
GR (1) GR3032493T3 (es)
HU (1) HU221276B1 (es)
NO (1) NO315942B1 (es)
NZ (1) NZ275339A (es)
PL (1) PL178879B1 (es)
PT (1) PT726902E (es)
RU (1) RU2139874C1 (es)
SI (1) SI0726902T1 (es)
SK (1) SK281510B6 (es)
WO (1) WO1995012599A1 (es)
ZA (1) ZA948542B (es)

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US5962499A (en) * 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5834260A (en) * 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
JP3502103B2 (ja) * 1996-09-19 2004-03-02 メルク エンド カンパニー インコーポレーテッド ノジュリスポリン酸誘導体
WO1999018796A2 (en) * 1997-10-09 1999-04-22 Rhone-Poulenc Agro Pesticidal combination
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US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
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CA2945453C (en) 2008-11-14 2021-03-02 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds
RU2011124948A (ru) 2008-11-19 2012-12-27 Мериал Лимитед Композиции, включающие 1-арилпиразол сам по себе или в комбинации с формамидином, для лечения паразитарных инфекций
EA019126B1 (ru) 2008-12-04 2014-01-30 Мериал Лимитед Димерные производные авермектина и милбемицина
ES2545738T3 (es) 2009-07-30 2015-09-15 Merial, Inc. Compuestos insecticidas a base de 4-amino-tieno[2,3-d]-pirimidina y procedimientos para su uso
AU2010325827B2 (en) 2009-12-04 2015-11-05 Basf Se Pesticidal bis-organosulfur compounds
BR112012014933B1 (pt) 2009-12-17 2020-10-27 Merial, Inc. composições que compreendem compostos lactonas macrocíclicas e spirodioxepinoindóis
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US20120295931A1 (en) 2010-02-05 2012-11-22 Lutz Juergen Spiroindoline compounds for use as anthelminthics
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
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KR20140094026A (ko) 2011-11-28 2014-07-29 이 아이 듀폰 디 네모아 앤드 캄파니 N-(4-퀴놀리닐메틸) 설폰아미드 유도체 및 구충제로서의 이의 용도
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US5399582A (en) * 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents

Also Published As

Publication number Publication date
HUT74959A (en) 1997-03-28
HU221276B1 (en) 2002-09-28
PL314190A1 (en) 1996-09-02
AU688405B2 (en) 1998-03-12
ZA948542B (en) 1995-06-27
CN1082543C (zh) 2002-04-10
CN1046943C (zh) 1999-12-01
KR960705828A (ko) 1996-11-08
PL178879B1 (pl) 2000-06-30
EP0726902B1 (en) 2000-01-05
DE69422526T2 (de) 2000-07-27
FI110871B (fi) 2003-04-15
KR100333017B1 (ko) 2002-09-27
FI961839L (fi) 1996-04-30
WO1995012599A1 (en) 1995-05-11
DK0726902T3 (da) 2000-05-01
SI0726902T1 (en) 2000-04-30
CZ124996A3 (en) 1996-10-16
US5399582A (en) 1995-03-21
NO315942B1 (no) 2003-11-17
FI20012318L (fi) 2001-11-27
CZ286032B6 (cs) 1999-12-15
NZ275339A (en) 1997-11-24
GR3032493T3 (en) 2000-05-31
NO961748D0 (no) 1996-04-30
US5614546A (en) 1997-03-25
ATE188476T1 (de) 2000-01-15
CA2174645C (en) 2004-09-07
CA2174645A1 (en) 1995-05-11
CN1137796A (zh) 1996-12-11
AU8092994A (en) 1995-05-23
PT726902E (pt) 2000-06-30
NO961748L (no) 1996-07-01
CN1236012A (zh) 1999-11-24
HU9601138D0 (en) 1996-06-28
DE69422526D1 (de) 2000-02-10
RU2139874C1 (ru) 1999-10-20
FI961839A0 (fi) 1996-04-30
JPH09505567A (ja) 1997-06-03
SK281510B6 (sk) 2001-04-09
EP0726902A1 (en) 1996-08-21
SK53996A3 (en) 1997-03-05
FI112503B (fi) 2003-12-15
JP3557212B2 (ja) 2004-08-25

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