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ES2093636T3 - Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica. - Google Patents

Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica.

Info

Publication number
ES2093636T3
ES2093636T3 ES90312642T ES90312642T ES2093636T3 ES 2093636 T3 ES2093636 T3 ES 2093636T3 ES 90312642 T ES90312642 T ES 90312642T ES 90312642 T ES90312642 T ES 90312642T ES 2093636 T3 ES2093636 T3 ES 2093636T3
Authority
ES
Spain
Prior art keywords
compound
prostaglandina
ceto
improvement
brain function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90312642T
Other languages
English (en)
Inventor
Ryuji Ueno
Hiroyoshi Osama
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R Tech Ueno Ltd
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8543990A external-priority patent/JPH07116135B2/ja
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ES2093636T3 publication Critical patent/ES2093636T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL USO DE UN COMPUESTO DE 15-QUETO-PROSTAGLANDINA PARA LA FABRICACION DE UN MEDICAMENTO PARA MEJORAR LA ACCION ENCEFALICA.
ES90312642T 1989-11-22 1990-11-21 Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica. Expired - Lifetime ES2093636T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30383989 1989-11-22
JP761190 1990-01-17
JP8543990A JPH07116135B2 (ja) 1990-03-30 1990-03-30 ６，１５―ジケト―５―ハロプロスタグランジンｅ類

Publications (1)

Publication Number Publication Date
ES2093636T3 true ES2093636T3 (es) 1997-01-01

Family

ID=27277677

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90312642T Expired - Lifetime ES2093636T3 (es) 1989-11-22 1990-11-21 Uso de un compuesto de 15-ceto-prostaglandina para la mejora de la funcion encefalica.

Country Status (9)

Country Link
US (3) US5117042A (es)
EP (1) EP0435443B1 (es)
KR (2) KR0147057B1 (es)
AT (1) ATE141793T1 (es)
CA (1) CA2030345C (es)
DE (1) DE69028289T2 (es)
DK (1) DK0435443T3 (es)
ES (1) ES2093636T3 (es)
GR (1) GR3020902T3 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101781A (zh) * 1993-02-03 1995-04-19 帝人株式会社 治疗脑血栓的药物组合物
HU223345B1 (hu) 1995-12-20 2004-08-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
ES2182088T3 (es) * 1996-06-10 2003-03-01 Sucampo Ag Antagonista de la endotelina.
US6680339B2 (en) 1996-11-12 2004-01-20 Alcon Manufacturing, Ltd. 15-fluoro prostaglandins as ocular hypotensives
EP0938472B1 (en) 1996-11-12 2001-06-27 Alcon Laboratories, Inc. 15-fluoro prostaglandins as ocular hypotensives
KR20010023838A (ko) * 1997-09-09 2001-03-26 데이비드 엠 모이어 Ｆｐ 작동약으로 유용한 방향족 ｃ16-ｃ20-치환된테트라히드로 프로스타글란딘
NZ503735A (en) * 1997-09-09 2001-05-25 Procter & Gamble Aromatic C16-20-substituted tetrahydro prostaglandin F analogues useful as FP agonists
ATE401894T1 (de) * 1997-11-28 2008-08-15 Sucampo Ag Verwendung von 15-keto-prostaglandin-e verbindungen als endothelin antagonisten
IL145122A0 (en) 1999-03-05 2002-06-30 Procter & Gamble C16 unsaturated fp-selective prostaglandin analogs
CN1268623C (zh) * 1999-10-15 2006-08-09 苏坎波公司 组合物和使该组合物稳定的方法
KR100788226B1 (ko) * 2000-03-24 2007-12-26 수캄포 아게 15-케토-프로스타글란딘 또는 이의 유도체를 포함하는세포자연사 억제 조성물
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
TWI263505B (en) 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
CN101146541B (zh) * 2005-01-27 2012-04-11 苏坎波公司 用于治疗中枢神经系统疾病的方法和组合物
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
WO2010083597A1 (en) 2009-01-22 2010-07-29 Apotex Pharmachem Inc. Methods of making lubiprostone and intermediates thereof
EP2739278A4 (en) 2011-08-05 2015-03-18 Sucampo Ag PROCESS FOR TREATING SCHIZOPHRENIA
CN104140410B (zh) * 2013-05-09 2017-12-15 江苏豪森药业集团有限公司 鲁比前列酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153858A3 (en) * 1984-02-29 1985-12-11 The Upjohn Company The therapeutic use of prostaglandins
JPS62198616A (ja) * 1986-02-24 1987-09-02 Res Dev Corp Of Japan 脳血流量改善・脳細胞保護剤
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
EP0292177B1 (en) * 1987-05-15 1992-03-25 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Fervescence composition
DE3876050T2 (de) * 1987-09-18 1993-03-25 Ueno Seiyaku Oyo Kenkyujo Kk Okulare hypotensivagenzien.
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
JP2597649B2 (ja) * 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
ES2055051T3 (es) * 1988-05-23 1994-08-16 Ueno Seiyaku Oyo Kenkyujo Kk Un metodo para la fabricacion de un medicamento eficaz para aumentar la presion sanguinea.
US5106809A (en) * 1990-12-14 1992-04-21 Exxon Research And Engineering Company High activity, high yield tin modified platinum-iridium catalysts, and reforming process utilizing such catalysts

Also Published As

Publication number Publication date
KR0167745B1 (ko) 1999-01-15
EP0435443B1 (en) 1996-08-28
DE69028289D1 (de) 1996-10-02
ATE141793T1 (de) 1996-09-15
DK0435443T3 (da) 1996-09-16
US5117042A (en) 1992-05-26
GR3020902T3 (en) 1996-11-30
KR0147057B1 (ko) 1998-08-17
EP0435443A2 (en) 1991-07-03
DE69028289T2 (de) 1997-01-09
CA2030345A1 (en) 1991-05-23
CA2030345C (en) 1998-12-08
US5426115A (en) 1995-06-20
EP0435443A3 (en) 1993-01-27
US5290811A (en) 1994-03-01
KR910009269A (ko) 1991-06-28

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