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ES2041802T3 - Sensores biologicos. - Google Patents

Sensores biologicos.

Info

Publication number
ES2041802T3
ES2041802T3 ES198888307641T ES88307641T ES2041802T3 ES 2041802 T3 ES2041802 T3 ES 2041802T3 ES 198888307641 T ES198888307641 T ES 198888307641T ES 88307641 T ES88307641 T ES 88307641T ES 2041802 T3 ES2041802 T3 ES 2041802T3
Authority
ES
Spain
Prior art keywords
point
light
layer
progress
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888307641T
Other languages
English (en)
Inventor
Martin Francis Finlan
Stephen Alexander Charles
James Christopher Irlam
John Edward Maurice Midgley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2041802(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719885A external-priority patent/GB8719885D0/en
Priority claimed from GB878720854A external-priority patent/GB8720854D0/en
Application filed by Amersham International PLC filed Critical Amersham International PLC
Application granted granted Critical
Publication of ES2041802T3 publication Critical patent/ES2041802T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SENSOR QUE UTILIZA EL PRINCIPIO DE RESONANCIA DE PLASMON SUPERFICIAL (SPR) PARA CONTROLAR EL PROGRESO DE LA REACCION ENTRE UNA MUESTRA (NO MOSTRADA) Y UNA CAPA SENSIBLE (20) (POR EJEMPLO, UNA CAPA ANTICUERPOS). LA CAPA (20) SE APLICA A LA SUPERFICIE POSTERIOR DE UNA PELICULA METALICA (19) FORMADA EN LA SUPERFICIE DE UN COMPONENTE TRANSMISOR OPTICO (28) EN FORMA DE UNA LENTE SEMICILINDRICA (11) Y UNA GUIA (16). LA LUZ COLIMADA DE UNA FUENTE (NO MOSTRADA) SE APLICA A TRAVES DE LA LENTE (2), LA CUAL ENFOCA EL HAZ INCIDENTE (1) A UN FOCO EN EL PUNTO (3) PARA FORMAR UN BARRIDO LUMINOSO EN ABANICO DE LA LUZ INCIDENTE EN EL PUNTO (3). LA LUZ SE REFLEJA INTERNAMENTE EN EL PUNTO 3 Y EMERGE DEL COMPONENTE (28) PARA INCIDIR EN UN SISTEMA DETECTOR (18) QUE POSTERIORMENTE SE EXPLORA ELECTRONICAMENTE. EL ANGULO DE INCIDENCIA DE LA LUZ EN EL PUNTO (3) ES TAL QUE ABARCA ESE ANGULO, LO QUE PROVOCA RESONANCIA DEL PLASMON SUPERFICIAL, JUNTO CON UNA SERIE DE ANGULOS DE FORMA QUE EL PROGRESO DEL ESTADO RESONANTE, AL DESARROLLARSE LA REACCION ENTRE LA MUESTRA Y LA CAPA SENSIBLE, PUEDE SER CONTROLADO.
ES198888307641T 1987-08-22 1988-08-18 Sensores biologicos. Expired - Lifetime ES2041802T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719885A GB8719885D0 (en) 1987-08-22 1987-08-22 Sensor arrangement
GB878720854A GB8720854D0 (en) 1987-09-04 1987-09-04 Biological sensors

Publications (1)

Publication Number Publication Date
ES2041802T3 true ES2041802T3 (es) 1993-12-01

Family

ID=26292635

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888307641T Expired - Lifetime ES2041802T3 (es) 1987-08-22 1988-08-18 Sensores biologicos.

Country Status (10)

Country Link
US (1) US4997278A (es)
EP (1) EP0305109B1 (es)
JP (1) JP2758904B2 (es)
KR (1) KR890004166A (es)
AT (1) ATE92186T1 (es)
AU (1) AU602423B2 (es)
CA (1) CA1321488C (es)
DE (1) DE3882620T2 (es)
ES (1) ES2041802T3 (es)
FI (1) FI94805C (es)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
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FI94805B (fi) 1995-07-14
JPH01138443A (ja) 1989-05-31
FI883868A0 (fi) 1988-08-19
KR890004166A (ko) 1989-04-20
EP0305109B1 (en) 1993-07-28
DE3882620D1 (de) 1993-09-02
ATE92186T1 (de) 1994-02-25
AU2110988A (en) 1989-02-23
AU602423B2 (en) 1990-10-11
JP2758904B2 (ja) 1998-05-28
DE3882620T2 (de) 1993-11-04
FI883868A (fi) 1989-02-23
CA1321488C (en) 1993-08-24
FI94805C (fi) 1995-10-25
US4997278A (en) 1991-03-05
EP0305109A1 (en) 1989-03-01

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