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EP2694463B8 - Behandlung von tumoren im zentralnervensystem mit coenzym q10 - Google Patents

Behandlung von tumoren im zentralnervensystem mit coenzym q10 Download PDF

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Publication number
EP2694463B8
EP2694463B8 EP12767439.8A EP12767439A EP2694463B8 EP 2694463 B8 EP2694463 B8 EP 2694463B8 EP 12767439 A EP12767439 A EP 12767439A EP 2694463 B8 EP2694463 B8 EP 2694463B8
Authority
EP
European Patent Office
Prior art keywords
coenzyme
nervous system
central nervous
system tumors
treating central
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP12767439.8A
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English (en)
French (fr)
Other versions
EP2694463B1 (de
EP2694463A4 (de
EP2694463A1 (de
Inventor
Joaquin J. Jimenez
Niven Rajin Narain
Rangaprasad Sarangarajan
John Patrick Mccook
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BERG LLC
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BERG LLC
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Filing date
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Publication of EP2694463A1 publication Critical patent/EP2694463A1/de
Publication of EP2694463A4 publication Critical patent/EP2694463A4/de
Publication of EP2694463B1 publication Critical patent/EP2694463B1/de
Application granted granted Critical
Publication of EP2694463B8 publication Critical patent/EP2694463B8/de
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP12767439.8A 2011-04-04 2012-04-04 Behandlung von tumoren im zentralnervensystem mit coenzym q10 Active EP2694463B8 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161471659P 2011-04-04 2011-04-04
PCT/US2012/032178 WO2012138765A1 (en) 2011-04-04 2012-04-04 Methods of treating central nervous system tumors

Publications (4)

Publication Number Publication Date
EP2694463A1 EP2694463A1 (de) 2014-02-12
EP2694463A4 EP2694463A4 (de) 2014-10-29
EP2694463B1 EP2694463B1 (de) 2019-09-04
EP2694463B8 true EP2694463B8 (de) 2019-10-09

Family

ID=46969535

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12767439.8A Active EP2694463B8 (de) 2011-04-04 2012-04-04 Behandlung von tumoren im zentralnervensystem mit coenzym q10

Country Status (9)

Country Link
US (3) US20120269867A1 (de)
EP (1) EP2694463B8 (de)
JP (3) JP6092844B2 (de)
KR (1) KR101933732B1 (de)
CN (1) CN103608323B (de)
AU (2) AU2012240222B2 (de)
CA (1) CA2832324C (de)
ES (1) ES2762451T3 (de)
WO (1) WO2012138765A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX345044B (es) 2009-05-11 2017-01-16 Berg Llc Métodos para el diagnóstico de trastornos oncológicos usando cambiadores epimetabólicos, moléculas intracelulares multidimensionales o influenciadores ambientales.
EP2694463B8 (de) 2011-04-04 2019-10-09 Berg LLC Behandlung von tumoren im zentralnervensystem mit coenzym q10
EP2983654A4 (de) 2013-04-08 2016-11-30 Berg Llc Behandlung von krebs mit coenzym-q10-kombinationstherapien
CA2919432A1 (en) * 2013-07-30 2015-02-05 Benemilk Oy Feed for lactating ruminants
KR102370843B1 (ko) 2013-09-04 2022-03-04 버그 엘엘씨 코엔자임 q10의 연속주입에 의한 암치료 방법
CN104173835A (zh) * 2014-09-03 2014-12-03 四川金堂海纳生物医药技术研究所 一种治疗淋巴管瘤的内服药物及其制备方法
MX2021006835A (es) 2018-12-14 2021-07-02 Colgate Palmolive Co Composiciones para el cuidado personal basadas en emulsiones sin silicona y metodos para estas.
US11883514B2 (en) * 2019-11-01 2024-01-30 Colgate-Palmolive Company Stable low pH personal care compositions and methods for the same
US20210322339A1 (en) * 2019-11-20 2021-10-21 Berg Llc Combination therapy of coenzyme q10 and radiation for treatment of glioma

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JP2014510144A (ja) 2014-04-24
AU2012240222A8 (en) 2013-11-14
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CN103608323A (zh) 2014-02-26
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US20120269867A1 (en) 2012-10-25
CA2832324A1 (en) 2012-10-11
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US20170246125A1 (en) 2017-08-31
WO2012138765A1 (en) 2012-10-11
KR101933732B1 (ko) 2018-12-28
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