EP1978912A1

EP1978912A1 - Packaging for medical products and similar

Info

Publication number: EP1978912A1
Application number: EP06841238A
Authority: EP
Inventors: Nikolai Strub; Gottfried Von Bismarck; Gerhard Breu
Original assignee: Koerber AG; AvidiaMed GmbH
Current assignee: AvidiaMed GmbH
Priority date: 2005-12-21
Filing date: 2006-12-21
Publication date: 2008-10-15
Anticipated expiration: 2026-12-21
Also published as: EP1973511A1; JP2009520536A; DK1973511T3; DK1978912T3; JP5081835B2; ATE533458T1; AU2006332071A1; PL1978912T3; AU2006332069B2; US8020702B2; PT1973511E; EP1973511B1; PL1973511T3; JP2009520651A; PT1978912E; WO2007077034A1; US20080302811A1; EP1800645A1; CA2634518A1; EP1973511B9

Abstract

The invention relates to packaging (10) for pharmaceutical and/or medicinal products (11) and/or food supplements, comprising a substrate (14) which is equipped with one or several preassembled, closed product carriers (16) which contain one or several, individual products (11), for a defined period of time and is provided with instructions for application and/or the administration time for the patient. Each product carrier (16) contains, respectively, exclusive products (11) of a special active substance or a special active substance combination in a special dosage. The invention is characterised in that each product carrier (16) comprises an unrollable and single-tracked blister packaging and the product carriers (16), containing one or several individual products (11), are arranged on the substrate (14) which is unique to the patient. The invention also relates to a method and to a device for producing said type of packaging (10).

Description

PACKAGING FOR MEDICAL PRODUCTS AND THE SAME

The invention relates to a packaging for pharmaceutical and / or medical products and / or dietary supplements, comprising a substrate which is equipped with one or more prefabricated, sealed product carriers, each containing one or more isolated products, for a defined period of time and with references to Application or intake time is provided for the patient, each product carrier in each case exclusively products of a special

Active ingredient or a special drug combination in a special dosage contributes. Furthermore, the invention relates to a method and an apparatus for producing said packages.

For the primary packaging of pharmaceutical and / or medical products and / or dietary supplements (which are also referred to as products hereinafter), tablets, dragees, ampoules, vitamin preparations but also syringes or the like may be mentioned by way of example, different requirements are of importance. On the one hand, there are constant efforts to make it easier for the patient to take the medication or to use the products. The existing ones

Packaging supports the patient in addition to the simplified removal of the product from the packaging by appropriate removal aids in the dosage and the temporal intake of the drugs. These aspects are commonly known by the terms "convenience" or "senior friendliness" (SF). On the other hand, the aspect of child safety, known as "child resistance" (CR), is of increasing regulatory importance, which means that current packaging is protected against unauthorized removal, in particular by children. However, especially in the case of pharmaceutical and / or medical products, the reliability of compliance with the prescribed medicaments is of particular importance, which is to be supported by the so-called compliance packaging. It has been found that patients more reliably take the medication prescribed to them when one or more and / or different medicaments are arranged side by side or together within a package and the required application or administration times are indicated by calendars and times. For example, in addition to antibiotics, stomach protection preparations are to be taken at the same time. The arrangement or composition of the medication after

The day of the week and the time of day make it easier for the patient to take his prescribed medication reliably, which is of particular importance for chronically ill patients.

On the market packaging is known and available, which ensure a patient-specific compilation of one or more products. The products are either filled directly as raw material or after unpacking from a package in the appropriate patient-specific packaging, eg in compartments of packaging units. However, this requires, on the one hand, that the filling must be carried out under defined clean-room conditions and with pharmaceutical specialists, which leads to very high costs. On the other hand, the partial manual unpacking and repackaging is prone to error, costly and expensive due to the multitude of work steps and furthermore leads to a mechanical loading of the products. Moreover, the packaging of medicines from raw materials and the handling of raw materials after unpacking are subject to special legal conditions, the fulfillment of which means a considerable outlay. In the known packages produced according to the methods described above, several different products / tablets may be arranged in a receiving space, such as a bag, a tubular bag, a nest of a blister pack or the like. However, this is particularly disadvantageous because of the risk of cross-contamination. To avoid such cross-contamination, there are efforts to place the products individually on a packaging in a closed state. That means the Products are arranged individually in a compartment of a packaging unit or a nest of blister packaging and packaged in such a way to put together for the patient intended packaging.

From EP 0 852 208 A1, furthermore, a tablet container with the features of the preamble of claim 1 is known. This package has a substrate on which several isolated products are arranged in sealed product carriers, wherein the dosage of the same drug or the same combination of active ingredients for the treatment of Parkinson's disease gradually (1st day one tablet, 2nd day one tablet, 3rd day two Tablets, 4th day, three tablets etc.) increases. The products are prefabricated in flat blisters. Such blisters have several columns and several lines, for example as 2x5 blisters. This means that the products lie one after the other in sealed nests of the blister tray / blister magazine. Locked in this context means that each product within the nest is enclosed on all sides with respect to the environment, so that the products are protected against external influences (mechanical stress or other contaminants, in particular biological or chemical contamination). Product carriers separated from the blister tray / blister magazine may contain one or more isolated products. These product carriers are then assembled into a therapy-specific packaging. In addition to the just mentioned disadvantage of a purely therapy-specific compilation of the products, an automated production of such packaging is also possible only with undue effort, since e.g. the separation of individual product carriers from a flat and multicellular blister tray has to take place in different directions. In summary, the packaging described in said EP-font is composed exclusively therapy-specific and automatically only uneconomical to produce.

It is therefore an object of the present invention to provide a secure, cost-effective and patient-specific packaging. Furthermore, it is the task of

Invention to propose a corresponding method and an apparatus for producing the packaging. - A -

The object is achieved on the one hand by a package having the features mentioned above in that each product carrier is part of a rollable and single-web blister pack and the product carriers containing one or more individual products are placed on the substrate individually on the substrate. Thus, a patient-specific packaging is created in a particularly simple and cost-effective manner, since the packaging or the substrate can be assigned one or more different products in a freely selectable amount. In other words, the packaging allows for each patient to have their own intake time of day._ A key advantage is that the products, from the actual production to the opening / removal by the patient

Patients are protected, since the products themselves are in the closed product carriers during and after the assembly of the patient-specific packaging and are thus exposed to neither mechanical and / or other influences of the environment nor to fear cross-contamination. The problems with handling raw materials can therefore be circumvented with this packaging and a sterile

Assembling can be ensured in a simple way. But that also means that a wide variety of products can be brought together by different manufacturers from a third party. The fact that each product carrier is part of a roll-up and single-line blister strip packaging means that the packaging can be produced automatically with simple means, which offers a considerable economic advantage, even with individual packaging (no packaging must be the same to others) and the number of packages produced.

The substrate preferably carries or forms a blister composite, such that a plurality of sections of the product-specific blister strip packs, each with different products, are applied to the substrate by one or more manufacturers. The packaging according to the invention for the first time ever created a package that combines in a particularly simple manner packaged products from several manufacturers and presented in a patient-individual way.

Advantageously, exactly one product is arranged in each nest of each blister strip packaging or each section of blister strip packaging. This can be in addition to the Prevention of cross-contamination of the further abrasion of the products can be prevented. Each product is optimal and maximally protected.

In a preferred continuation of the invention, the packaging is produced fully automatically. As a result, a faultless assembly of the products is guaranteed to a packaging, so that incorrect medications are avoided. The automatic production also ensures the required cost-effectiveness of the packaging.

On the other hand, the object is achieved by a method for producing a packaging for pharmaceutical and / or medical products and / or

Supplements are solved by the following steps: Provision of a substrate, selection of patient-specific products for a defined period of time, separation of pre-assembled, sealed product carriers with the selected, patient-specific products of rollable and single-lane

Blister packs, each product carrier each carrying only one or more products of a specific drug or a specific drug combination in a specific dosage, and automatically positioning and fixing the separated product carriers on the substrate according to the patient-specific requirements. By this method, it is possible in a particularly simple way to produce patient-specific packaging economically, since the individual products can be separated without unpacking and repackaging in the desired amount of Blistergurtverpackung and assembled to form a Blisterverbundes. The fact that the products are always protected, ie from the production to the removal by the patient in the nest of

Blister belt packaging lie, the compilation of the products can be made to a patient-specific packaging by third parties who are not manufacturers of pharmaceutical products / drugs. This increases the flexibility in the production of the final packaging. By providing the products on roll-up blister straps, which are particularly easy to machine, a particularly simple combination of different products is guaranteed by different manufacturers to a device for the production of the packaging. Advantageously, the packaging is made automatically, which can reduce errors in the selection and compilation of the products.

The object is also achieved by a device which is characterized in that it is a transport element for feeding and discharging individual substrates forming blanks, Aufhahmeplätze for blister belts or the like, in which the products are arranged singly, each Aufhahmeplatz a release agent for separating the product carrier or the sections of the blister strip is assigned, as well as a placement head for transporting the product carrier or sections separated from the blister strip from a provision position to the dispensing position on the substrate.

Further advantageous features and further developments of the packaging and the device as well as further preferred method steps emerge from the

Subclaims and the description. The packaging, the device and the manufacturing method will be explained with reference to the accompanying drawings. In the drawing shows:

1 shows a schematic representation of a packaging with an exemplary patient-specific compilation of the medicaments,

2 shows an enlargement of the detail II in FIG. 1,

3 shows a schematic representation of a further packaging with a patient-specific compilation of the medicaments,

4 shows a schematic representation of a further packaging with a patient-specific compilation of the medicaments,

5 shows a schematic representation of a further packaging with a patient-specific composition of the medicaments, Fig. 6 is a schematic sectional view of the packages according to the figures 1 to 5, and

7 shows a schematic representation of a device for producing packaging according to FIGS. 1 to 5.

The packaging described below is used for patient-specific and individual care of patients with pharmaceutical and / or medical products and / or nutritional supplements. In particular, the packages are used to hold tablets, dragees or the like.

Each of the packaging 10 shown is provided or equipped with products 11 for a defined period of time, whereby the individual therapy can last for a very long time, in particular for chronically ill patients. In this case, the time period as in the embodiments shown may be e.g. be defined as weekly calendar 12. However, monthly or quarter graduations may also be provided on the packages 10. In addition to the period, the packaging 10 has instructions or information 13 about the actual application or administration times.

The package 10 comprises a substrate 14, which may be made of cardboard, plastic or other suitable materials. The substrate 14 may be flat, ie fan-free or, as in the exemplary embodiments, designed as a folding element 15, for example, to form a so-called wallet packaging. The above-mentioned weekly calendar 12 and the information 13 are on the preferably cut-existing substrate 14 e.g. applied by printing, embossing or the like. The substrate 14 may each have a perforation or other material weakening in columns and rows in order to simplify a section-wise separation of individual rows and / or columns.

On the substrate 14 prescription and / or pharmacy and / or freely available products 11 are arranged. These products 11 are protected on or within product carriers 16. The product carriers 16 are part of a prefabricated (not explicitly shown) type of packaging, in particular a blister (gurt) packaging. The prefabricated product carriers 16 are subdivided into sections 17 by separating them from the blister pack, each section 17 having exclusively products 11 of one type or, more particularly, of a specific active substance or a specific combination of active substances with a defined dose. In other words, each product type is associated with its own product carrier 16. The product carriers 16 and / or sections 17 have so-called nests 18 in a manner customary for blister packs, each of which is designed to receive a single product 11. In other words, each nest 18 is assigned only a single product 11. Preferably, each product 11 of the product carrier 16 is individually identified uniquely with a corresponding optical code. The nests 18 are covered by a film 26 or the like or closed so that they are completely shielded from the environment. The individual product carriers 16 or the corresponding sections 17 form a blister composite 19 with the substrate 14. Such a blister composite 19 can accordingly have a plurality of sections 17 separated from a blister strip, the sections 17 being identical or different (from different blister straps). Products 11 may contain from one or more manufacturers. The sections 17 are arranged in the form of a matrix with columns and rows according to administration, wherein a first section 17 one or more separately each housed in a nest 18 copies example of a drug A and a second section 17 one or more separately from each other in a nest 18 encased specimens example of a drug B has. The number of rows and the number of columns correspond to an x-time intake on one day and a revenue period of y days.

Depending on the need, requirement or recipe, the products 11 are individually selected and applied with their respective product carriers 16 on the substrate 14. In this case, the product carriers 16 or the sections 17 are firmly connected to the substrate 14, for example by heat bonding or the like. However, other common mounting options or means such as by clamping or the like are also possible. The substrate 14 itself can serve as a package 10. But the substrate 14 can also be arranged on or in an outer packaging. Preferably, the substrate 14 or individual parts of the substrate carrying the product carriers 16 with the products 11 are detachably arranged on the outer packaging, so that they can optionally be fed to a preferably electronic dispensing device. In other words, the package 10 can be combined with measures of the SF and CR described above.

The substrate 14 may have perforated or pre-punched areas through which the products 11 can be pressed out of the product carriers 16. As can be seen from FIG. 6, these regions can also be formed as an opening 20. The product carrier 16 or the sections 17 lie on one side (top or

Bottom) on the substrate 14. On the other hand, the product carrier 16 may be at least partially covered by a cover element 21. In such cases, the product carriers 16 are sandwiched between the cover element 21 and the substrate 14. In this case, the cover element 21 likewise has openings 22 through which the nests 18 protrude with the products 11 (see in particular FIG. 6). It should be understood, however, that the package 10 may be formed solely from a substrate 14 having the product carriers 16 disposed thereon or underneath. In other words, the product carriers 16 can be fed from one side with cardboard or the like, e.g. the substrate 14, or from both sides with cardboard or the like, e.g. the substrate 14 and the lid member 21, at least partially covered. With such a cover element 21, the product carrier 16 or sections 17 can additionally be fixed and positioned relative to the substrate 14 as well as with each other.

The package 10 is associated with further information 23, wherein this information 23 is attached as a package insert and / or arranged in printed form on the substrate 14 or other surfaces of the package 10. For example, information about the individual medicines, the manufacturers or other relevant messages can be removably inserted into a slot or adhered to the package 10 as a leaflet or booklet. Information on patient data, by way of example, a patient photo may be mentioned here, date of manufacture of the products 11, treating physician, responsible pharmacy, health insurance, producing bottler, distributor, and other necessary for an unmistakable assignment and / or tracing, etc., as well as logos and brands of manufacturers and other information may be printed on the package 10. The information 12, 13, 23 may be glued, printed and / or embossed (eg in Braille) or applied in another known manner, the positioning of the information 12, 13, 23 preferably laterally on the substrates 14, the product carriers 16 etc. can be arranged. In addition, for example, for accounting reasons, a consecutive number or the like may be formed on the packaging 10. Also, the package may be attached to 10 media, audio media or other media.

Some of the information, in particular about the contents of the package 10, may be too

For the purpose of simple checking / checking or for comparison e.g. with the recipe data also in coded form e.g. be arranged as a bar code 24 or the like on the package 10. In principle, all information 12, 13, 23 can be embodied in legibly written form and / or as coding, for example with a luminophore marking. In addition, the packaging 10 may have an electronic component 25, in particular a memory chip. By means of this device 25 is also a communication to external systems for purposes of control, testing or the like possible.

The above-described packaging 10 may be made manually or automatically. In this case, the most diverse types of packaging may be formed, for example a packaging 10 with one and the same product of a manufacturer or a packaging 10 with different products and / or the same products with different doses of an active ingredient of a manufacturer or a packaging 10 with products from different manufacturers. Any other combinations are also possible. Selected examples are explained below.

1 to 5 each show a package 10 which contains a "weekly ration" for a specific patient, whereby six different ones are present in the package according to FIG. 1, which represents, for example, a possible therapy scheme for a long-term therapy of a chronic disease Products (A to F) of different manufacturers in sometimes different dosages stocked in. The number of products to be taken 11 varies Information about the manufacturer carries the packaging 10 also product notes (see in particular Figure 2). In the package 10 according to FIG. 3, all products 11 which correspond to the active substance and the dosage are from a manufacturer. In addition to the manufacturer's instructions, information on the medicament itself (name, active substance, dosage, etc.) may alternatively also be indicated on the packaging 10. It can be seen from the packaging 10 according to FIG. 3 that in addition to sections 17 with one or two nests 18, continuous section strips (eg from Monday to Thursday in the 8 o'clock line) can also be provided in a field of the matrix. In the packaging 10 according to FIG. 4, two medicaments from different manufacturers are assembled. The package 10 according to FIG. 5 individually provides the patient with three different products (drug I from manufacturer A, drug II from manufacturer B and drug III from manufacturer C) from three different manufacturers. In addition, another drug I from manufacturer A with the same active ingredient in a lower dosage (administration time 20.00 clock) is part of the packaging 10. The way of compilation is therefore arbitrary (freely programmable) and can be supplemented for example by additional vitamin supplements, dietary supplements, etc. ,

FIG. 7 shows by way of example a device 27 for producing the described packages 10. The device 27 has a transport element 28 for transporting individual blanks 29, which form the substrates 14, through the device 27 and past a placement head 30. Preferably on both sides of the transport element 28, but also on one side Aufhahmeplätze 31 are provided for rollers 32, magazines or the like, the rollers 32, magazines or the like preferably carry rolled blister straps for the products 11. Of the

Placement head 30 is preferably arranged centrally and serves for transporting the product carrier 16 or sections 17 separated from the blister strip from a supply position 33 to the delivery position on the substrate 14. The device 27 comprises a separating means for each receiving space 31, by means of which the product carriers 16 or sections 17 can be separated from the blister strip. In

Transport direction T at the output of the device 27 is a printing station 34 is arranged, by means of which the information 12, 13, 23 can be placed on the package. The placement head 30 has several axes of movement (linear X, Y, Z axis and axis of rotation) and is optionally also linear and / or movable on a circular path and has a control for the automatic and individual execution of the individual manufacturing orders. The placement head 30 is preferably connected to an optical reading device in order to check the correct recording of the sections 17 on-line by means of an optical code on the products 11 or the sections 17. For receiving and / or executing the orders, the device 27 can be networked and even be part of a network and thus, for example, integrated in a logistics system.

The method for producing the packaging 10 described above is explained in more detail below:

At the device 27 a plurality of rollers 32 are equipped with rolled up blister straps, each blister strip carrying only one product type (same active ingredient in the same dosage) and each product 11 is located separately in a nest 18 of the blister strip. The apparatus 27 is fed with a blank 29, for example the substrate 14. These blanks 29 can be standardized for patient groups, packaging groups (weekly pack, monthly pack, etc.) and blank or preprinted (for example with a weekly calendar, time scale or the like). The device 27 is manually or automatically given an order to produce a package 10, wherein the order the patient-specific data

(which drug, what amount, etc.). Once the data is loaded, the job is run by selecting the products 11 (one or more manufacturers and / or one or more dosages, etc.) and cutting or otherwise separating them from the rolls 32 or pre-assembled product carriers 16, respectively. The product carrier 16 or sections 17 separated from the belt are then conveyed to the supply position 33 and are picked up there by the placement head 30 which is movable over a plurality of axes (eg X, Y, Z axis) and supplied to the substrate 14. Previously, the substrate 14 may have been provided with adhesive dots or the like, the positions of the adhesive dots resulting from the arrangement of the sections 17 to be loaded on the substrate 14. The sections 17 are placed on the adhesive dots, so that a firm connection between the sections 17 and the substrate 14 is formed. Other connection techniques are also possible. After the complete assembly of the substrate 14, the correct assembly and Placement of each section 17 is checked by optical methods and then applied to the cover element 21, which is part of the blank 29 as a folding element or is supplied separately. The blister composite 19 formed by the substrate 14 populated with a plurality of sections 17 is then fed to the printing station 34 and provided with the desired information. Subsequently, the package 10 is prepared for shipment. The blister strip packs or the like to be subdivided into sections 17 may also be in stock on the device 27 in unrolled, folded, unfolded or other dosage form and processed.

Optionally, additional control and / or backup steps, e.g. be made by reading manufacturing, patient data or other information in the memory chip 25. By means of the coding 24 further testing or securing steps can be carried out. As described, the production of the packages 10 usually takes place automatically. In this case, job data (such as a recipe) can be fed directly to the device 27 and implemented by it. Usually, the method is computer-aided.

In abstract terms, the method can also be described as follows: To supply patients with a patient-specific requirement for a defined intake period for a drug A and / or a medicament B, it is proposed that the medicament A be arranged in a plurality of separate housings spaced apart from each other Specimens EA of the drug A carrying carrier C and / or the drug B in a plurality of each separately housed spaced apart arranged copies EB of the drug B carrying carrier D provide from the carrier C sections CA with one or more copies EA of the drug A and / or separate from the carrier D sections DB with one or more copies of the drug B and to arrange the separated sections CA and / or DB in a matrix-like formation on a substrate in accordance with income.

With the above-described type of packaging as well as the method and apparatus for producing the packaging is a particularly efficient and cost-effective Method for the distribution of pharmaceutical and / or medical products 11 or packaging 10 can be realized, which is described below in more detail: Specifically, the method can take the example of tablets as follows: A distribution center manufactures patient-specific packaging. A client supplies the information necessary for putting together the packaging. The information may be transmitted orally, in writing or usually in electronic form. Patients can be patients themselves as long as they are over-the-counter and non-pharmacy products / tablets. In general, however, the information contains prescription data that is created by a doctor and transmitted by this or by a pharmacy directly to the distribution center.

The tablets required for the collection of the desired content and quantity individual packaging can be supplied directly to the distribution center by different manufacturers. In the event that the tablets are delivered as raw materials to the distribution center, the distribution center fills the tablets themselves into blister straps so that the tablets are in pre-assembled blister straps for further processing. Each blister strip is assigned only a product of a specific active ingredient or a special combination of active ingredients with a special dosage. On the blister strip itself, only one tablet is assigned to each nest of the blister strip. The individual packaging 10 is then assembled from these prefabricated blister straps. For the usual case of pills being filled in blister straps directly at the actual producer of the tablets, the manufacturers deliver the blister straps to the distribution center.

Depending on the catchment or supply area, the distribution center is regionally oriented. This means that the distribution center ensures the assembly and delivery of the individual packaging in a locally defined area. There are usually several regional distribution centers that can be supplied directly by the manufacturers. However, it may also be provided a national, national or international distribution center. The parent distribution center receives the tablets from one or more manufacturers in turn as raw materials and / or packed in blister straps. The blister straps and blister straps filled with the raw material from the distribution center then become either delivered directly to one or more regional distribution centers and / or to a logistics unit, whereby the logistics unit may also be divided into several smaller units.

Regardless of the supply of the packaging 10 producing

Distribution Center has stocked the latter with the most popular and widely prescribed products 11 as well as the most widely used combination products. This means that on the basis of detailed information and empirical values, those preparations are needed that are needed for the compilation of individual packages. Even if individual products 11 should not be available in the distribution center, these products 11 can be obtained at short notice from the manufacturer and / or from the higher-level distribution center and / or from the logistics unit.

The clients can be networked with the distribution center to transfer orders. The transfer of information can also be done by conventional means by e-mail or in other usual computer-aided way. The incoming orders can be processed automatically and computer-controlled within the distribution center by means of suitable devices 27 by separating the selected products 11 from the stocked blister straps in a predetermined amount and depositing them on a blank 27, substrate 14 or the like supplied to the device 27. The resulting patient-specific blister packs or packaging 10 can then be labeled, coded or otherwise marked and tested before delivery, in particular with electronic aids.

In addition, the distribution center is optionally also connected to the logistics unit and / or the parent distribution center and / or the manufacturers. This connection can be made by conventional means of communication or be ensured by networking. Also, several distribution centers can be networked together. Through the connections, in particular products 11 or blister belts can be supplied as required and / or order-controlled to the or each distribution center producing the packaging 10. Also is the Stocking with the relevant products 11 or blister straps within the stations is easy to ensure.

The produced packaging 10 can be delivered by the distribution center itself or by the logistics unit quasi as a courier service to the client, for example a pharmacy or directly to the patient.

Claims

claims

Packaging (10) for pharmaceutical and / or medical products (11) and / or food supplements, comprising a substrate (14) which is filled with one or more prefabricated, closed product carriers (16), each containing one or more isolated products (11 ), populated for a defined period of time and with instructions for the application or

Taking time for the patient is provided, with each product carrier

(16) carries in each case exclusively products (11) of a specific active substance or a special combination of active substances in a specific dosage, which indicates that each product carrier (16) is part of a rollable and single-web blister pack and each one or more isolated products (16) 11) containing product carrier (16) patient-individually on the substrate (14) are assembled.

2. Packaging according to claim 1, characterized in that the substrate (14) carries or forms a blister composite (19), such that a plurality of sections

(17) of the product-specific Blistergurtverpackungen each having different isolated products (11) of an active substance or a drug combination of one or more manufacturers on the substrate (14) are applied.

3. Packaging according to claim 2, characterized in that in each nest

(18) of each blister strip package or section (17) of the blister strip packs, exactly one product (11) is arranged.

4. Packaging according to one of claims 1 to 3, characterized in that the product carrier (16) or sections (17) are fixedly connected to the substrate (14).

5. Packaging according to claim 4, characterized in that the product carrier

(16) or the sections (17) are glued to the substrate (14).

6. Packaging according to one of claims 1 to 5, characterized in that the substrate (14) is detachably arranged on a wrapping around.

7. Packaging according to one of claims 1 to 6, characterized in that the or each product carrier (16) between the substrate (14) and a

Cover element (21) is arranged.

8. Packaging according to one of claims 1 to 7, characterized in that the substrate (14) or the product carriers (16) information (12, 13) are assigned to days of the week and time of taking or application of the products (11).

9. Packaging according to one of claims 1 to 8, characterized in that on the substrate (14) information (23) for the patient and / or to the or each product (11) and / or to the manufacturers are shown.

10. Packaging according to claim 8 or 9, characterized in that the information (12, 13, 23) as a legible real font and / or as an encoding on the package (10) are shown.

11. Packaging according to one of claims 1 to 10, characterized in that the substrate (14) is associated with an electronic component (25) for storing data and / or information.

12. Packaging according to one of claims 1 to 11, characterized in that it is produced fully automatically.

13. A process for producing a packaging for pharmaceutical and / or medical products (11) and / or food supplements, characterized by the following steps:

Providing a substrate (14),

- selecting patient-specific products (11) for a defined period of time, Separating pre-assembled, sealed product carrier (16) with the selected, patient-specific products (11) of rollable and single-lane Blistergurtverpackungen, each product carrier (16) each one or more isolated products (11) of a specific drug or a special

Active ingredient combination carries in a special dosage, and automatically positioning and fixing the separated product carrier (16) on the substrate (14) according to the patient-specific specifications.

14. The method according to claim 13, characterized in that by applying a plurality of sections of the product-specific Blistergurtverpackungen a Blisterverbund (19) is formed, wherein the Blisterverbund (19) from product carriers (16) with products (11) of different manufacturers can be formed.

15. The method according to claim 13 or 14, characterized in that the or each product carrier (16) is glued to the substrate (14).

16. The method according to any one of claims 13 to 15, characterized in that after the positioning and fixing of the product carrier (16) on the substrate

(14) a cover element (21) is applied to the substrate (14) so that the or each product carrier (16) between the cover element (21) and the substrate (14) is arranged.

17. The method according to any one of claims 13 to 16, characterized in that the substrate (14) or the product carrier (16) with information (12, 13) is marked on weekdays and time of ingestion or application.

18. The method according to any one of claims 13 to 17, characterized in that on the substrate (14) information (23) to the patient and / or to the or each product (11) and / or to the manufacturers are printed.

19. The method according to any one of claims 13 to 18, characterized in that manufacturing and / or product information in an electronic component (25) of the substrate are read.

20. The method according to any one of claims 13 to 19, characterized in that the selection of the patient-specific products (11) is based on a recipe.

21. The method according to any one of claims 13 to 20, characterized in that the packaging (10) is produced automatically.

22. The method according to any one of claims 13 to 21, characterized in that it is carried out computerized.

23. The method according to claim 21 or 22, characterized in that the

Patient information with the respective individual medication directly by the doctor or a pharmacy or a clinic or other authorized persons on-line to a device (27) to assemble the package (10) are directed.

24. A device for producing a packaging in particular according to one of claims 1 to 12, comprising a transport element (28) for feeding and discharging the individual substrates (14) forming blanks (29), receiving places (31) for blister belts or the like, in which the products (11) are arranged isolated and sealed, with each receiving place

(31) a separating means for separating the product carrier (16) or the sections (17) is associated with the blister strip, and a placement head (30) for transporting the blister separated product carrier (16) and sections (17) from a supply position ( 33) to the dispensing position on the substrate (14).