[go: up one dir, main page]

EA200702254A1 - Вакцинная композиция, содержащая в-субъединицу термолабильного токсина e.coli и антиген и адъювант - Google Patents

Вакцинная композиция, содержащая в-субъединицу термолабильного токсина e.coli и антиген и адъювант

Info

Publication number
EA200702254A1
EA200702254A1 EA200702254A EA200702254A EA200702254A1 EA 200702254 A1 EA200702254 A1 EA 200702254A1 EA 200702254 A EA200702254 A EA 200702254A EA 200702254 A EA200702254 A EA 200702254A EA 200702254 A1 EA200702254 A1 EA 200702254A1
Authority
EA
Eurasian Patent Office
Prior art keywords
toxin
adjuvant
antigen
vaccine composition
thermolable
Prior art date
Application number
EA200702254A
Other languages
English (en)
Inventor
Мэриэнн Дьюэрчин
Original Assignee
Глаксосмитклайн Байолоджикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0510280A external-priority patent/GB0510280D0/en
Priority claimed from GB0524407A external-priority patent/GB0524407D0/en
Application filed by Глаксосмитклайн Байолоджикалс С.А. filed Critical Глаксосмитклайн Байолоджикалс С.А.
Publication of EA200702254A1 publication Critical patent/EA200702254A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Согласно настоящему изобретению предложена вакцинная композиция, содержащая В-субъединицу термолабильного токсина Е. coli или его производного с гомологией, равной или превышающей 90%, в комплексе с антигеном и адъювантом.
EA200702254A 2005-05-19 2006-05-18 Вакцинная композиция, содержащая в-субъединицу термолабильного токсина e.coli и антиген и адъювант EA200702254A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0510280A GB0510280D0 (en) 2005-05-19 2005-05-19 Vaccines
GB0524407A GB0524407D0 (en) 2005-11-30 2005-11-30 Vaccines
PCT/GB2006/001832 WO2006123155A2 (en) 2005-05-19 2006-05-18 Vaccine composition comprising b-subunit of e. coli heat toxin and an atigen and an adjuvant

Publications (1)

Publication Number Publication Date
EA200702254A1 true EA200702254A1 (ru) 2008-06-30

Family

ID=37431620

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702254A EA200702254A1 (ru) 2005-05-19 2006-05-18 Вакцинная композиция, содержащая в-субъединицу термолабильного токсина e.coli и антиген и адъювант

Country Status (13)

Country Link
US (1) US20090035330A1 (ru)
EP (1) EP1881844A2 (ru)
JP (1) JP2008540625A (ru)
KR (1) KR20080018201A (ru)
AU (1) AU2006248725A1 (ru)
BR (1) BRPI0610061A2 (ru)
CA (1) CA2608979A1 (ru)
EA (1) EA200702254A1 (ru)
IL (1) IL187008A0 (ru)
MA (1) MA29459B1 (ru)
MX (1) MX2007014390A (ru)
NO (1) NO20075727L (ru)
WO (1) WO2006123155A2 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229045A1 (en) * 2001-02-01 2002-08-07 Institut Curie Universal carrier for targeting molecules to Gb3 receptor expressing cells
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
EP2076531B1 (en) 2006-10-12 2011-11-23 Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. Telomerase reverse transcriptase fusion protein, nucleotides encoding it, and uses thereof
EP2034022A1 (en) 2007-09-10 2009-03-11 Universite Libre De Bruxelles Leukotriene B4 binding soluble lipocalin receptor from ixodes ricinus
EP2045263A1 (en) 2007-10-02 2009-04-08 Universite Libre De Bruxelles Identification and molecular characterisation of salivary metalloproteases expressed in the tick salivary glands
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
WO2010147268A1 (ko) * 2009-06-19 2010-12-23 아이진 주식회사 자궁경부암 백신
TW201103980A (en) 2009-07-08 2011-02-01 Abbott Biologicals Bv Viral vaccine and use thereof
CN106170551B (zh) 2013-12-16 2020-01-07 财团法人农业科技研究院 生产不耐热肠毒素b亚单位的质粒、方法及其套组
US20170305974A1 (en) * 2014-08-08 2017-10-26 Idemitsu Kosan Co., Ltd. Agent for controlling porcine reproductive and respiratory syndrome
JP6423889B2 (ja) 2014-10-07 2018-11-14 サイトリミック株式会社 Ｈｓｐ７０由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法
ES2805829T3 (es) 2015-03-09 2021-02-15 Cytlimic Inc Péptido derivado de GPC3, composición farmacéutica para el tratamiento o la prevención de cáncer usando el mismo, inductor de inmunidad y método para producir células presentadoras de antígeno
BR112017020404A2 (pt) 2015-04-07 2018-07-10 Cytlimic Inc. medicamento
BR112019006075A2 (pt) 2016-10-11 2019-06-18 Cytlimic Inc medicamento
CN111333734B (zh) * 2020-03-31 2022-05-03 中国人民解放军军事科学院军事医学研究院 一种百日咳丝状血凝素融合蛋白及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278302A (en) * 1988-05-26 1994-01-11 University Patents, Inc. Polynucleotide phosphorodithioates
US5843464A (en) * 1995-06-02 1998-12-01 The Ohio State University Synthetic chimeric fimbrin peptides
US5666153A (en) * 1995-10-03 1997-09-09 Virtual Shopping, Inc. Retractable teleconferencing apparatus
US6764840B2 (en) * 1997-05-08 2004-07-20 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US6303347B1 (en) * 1997-05-08 2001-10-16 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
JP2002542203A (ja) * 1999-04-19 2002-12-10 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム ワクチン
US6558670B1 (en) * 1999-04-19 2003-05-06 Smithkline Beechman Biologicals S.A. Vaccine adjuvants
GB0411411D0 (en) * 2004-05-21 2004-06-23 Glaxosmithkline Biolog Sa Vaccines

Also Published As

Publication number Publication date
EP1881844A2 (en) 2008-01-30
CA2608979A1 (en) 2006-11-23
MA29459B1 (fr) 2008-05-02
IL187008A0 (en) 2008-02-09
BRPI0610061A2 (pt) 2016-11-29
WO2006123155A3 (en) 2007-07-19
NO20075727L (no) 2008-02-15
WO2006123155A2 (en) 2006-11-23
AU2006248725A1 (en) 2006-11-23
US20090035330A1 (en) 2009-02-05
KR20080018201A (ko) 2008-02-27
MX2007014390A (es) 2008-02-12
JP2008540625A (ja) 2008-11-20

Similar Documents

Publication Publication Date Title
EA200702254A1 (ru) Вакцинная композиция, содержащая в-субъединицу термолабильного токсина e.coli и антиген и адъювант
DK1534335T3 (da) FcgammaRIIB-specifikke antistoffer og fremgangsmåder til anvendelse deraf
EA200701825A1 (ru) Вакцины против хламидиоза
EP1499191A4 (en) REGULATED ATTENUATION OF LIVE VACCINES TO ENHANCE CROSS-PROTECTIVE IMMUNOGENICITY
ATE552267T1 (de) Immungene von uropathogenen escherichia coli
ATE426412T1 (de) Adjuvante influenza-vakzine
MA30153B1 (fr) Anticorps anti-ox40l et methodes correspondantes
CY1105349T1 (el) Θειαζολυλ-αναστολεις τυροκινασεων της οικογενειας tec
MXPA05009682A (es) Metodos de radiofluorinacion de vectores biologicamente activos.
SE0102327D0 (sv) A novel engineered superantigen for human therapy
DE602004024542D1 (de) Untereinheit-impfstoff gegen das respiratorische synzytialvirus
BR0306905A (pt) Vacinas de flavivìrus
CY1108808T1 (el) Ενωσεις μοτιλιδης
DK1618128T3 (da) Tuberkulosevaccine med forbedret effektivitet
NO20015074D0 (no) Nye sammensetninger
WO2006042149A3 (en) Determining and reducing immunoresistance to botulinum toxin therapy using botulinum toxin a peptides
DE60011560D1 (de) Salmonella Impfstoff, der keinen Antikörper gegen Flagellin oder gegen Flagella induziert
ATE458496T1 (de) Hiv-vakzine und anwendungsverfahren
TW200630367A (en) Substituted adenines and the uses thereof
ATE533778T1 (de) Polynukleotide von haemophilus parasuis und anwendung davon
CL2008002223A1 (es) Compuestos derivados de 9-desoxo-9a-metil-9a-aza-9a-homoeritromicina a 2'-o-sustituida; proceso de preparación; compuesto intermediario; composición farmacéutica; y su uso en el tratamiento y/o profilaxis de la malaria.
NZ591738A (en) Non-typhoidal salmonella vaccines comprising a polypeptide which is an outer membrane protein d of non typoidal salmonella
DE602005007858D1 (de) Medizinische seife
ATE544856T1 (de) Peptid- und nukleotidsequenzen von anisakis spp. und ihre verwendung
DE602005021757D1 (de) Zur gattung bacillus gehörendes mutantes bakterium