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EA200600558A1 - Антитела против m-csf - Google Patents

Антитела против m-csf

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Publication number
EA200600558A1
EA200600558A1 EA200600558A EA200600558A EA200600558A1 EA 200600558 A1 EA200600558 A1 EA 200600558A1 EA 200600558 A EA200600558 A EA 200600558A EA 200600558 A EA200600558 A EA 200600558A EA 200600558 A1 EA200600558 A1 EA 200600558A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies
csf
relates
present
human anti
Prior art date
Application number
EA200600558A
Other languages
English (en)
Other versions
EA011669B1 (ru
Inventor
Вахе Бедиан
Мадхав Нарасимха Девалараджа
Джозеф Эдвин Лоу
Джеймс Лесли Мобли
Зирид-Аймее Келлерманн
Ян ФОЛТЦ
Мэри Хаак-Френдшо
Original Assignee
Уорнер-Ламберт Компани Ллс
Абдженикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33300142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200600558(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Уорнер-Ламберт Компани Ллс, Абдженикс, Инк. filed Critical Уорнер-Ламберт Компани Ллс
Publication of EA200600558A1 publication Critical patent/EA200600558A1/ru
Publication of EA011669B1 publication Critical patent/EA011669B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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Abstract

Настоящее изобретение относится к антителам или к их антигенсвязывающим частям, которые специфически связываются с M-CSF, а предпочтительно с человеческим M-CSF, и которые ингибируют M-CSF. Настоящее изобретение также относится к человеческим анти-M-CSF-антителам и к их антигенсвязывающим частям. Настоящее изобретение также относится к антителам, которые представляют собой химерные, биспецифические, дериватизированные, одноцепочечные антитела и части гибридных белков. Настоящее изобретение также относится к выделенным тяжелой и легкой цепям иммуноглобулинов, происходящих от человеческих анти-M-CSF-антител, и к молекулам нуклеиновой кислоты, кодирующим такие иммуноглобулины. Настоящее изобретение также относится к способам получения человеческих анти-M-CSF-антител и композиций, содержащих эти антитела, и к способам применения указанных антител и композиций для диагностики и лечения. Настоящее изобретение также относится к способам генотерапии, в которых используются молекулы нуклеиновой кислоты, кодирующие молекулы тяжелой и/или легкой цепей иммуноглобулина, включая человеческие анти-M-CSF-антитела. Настоящее изобретение также относится к трансгенным животным и трансгенным растениям, содержащим молекулы нуклеиновой кислоты согласно изобретению.
EA200600558A 2003-09-10 2004-09-09 Антитела против m-csf EA011669B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50216303P 2003-09-10 2003-09-10
PCT/US2004/029390 WO2005030124A2 (en) 2003-09-10 2004-09-09 Antibodies to m-csf

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KR101460477B1 (ko) 2013-06-18 2014-11-10 주식회사 엘지화학 연신 적층체, 박형 편광자의 제조 방법, 이를 이용하여 제조되는 박형 편광자 및 이를 포함하는 편광판
JP6319584B2 (ja) 2015-02-27 2018-05-09 京セラドキュメントソリューションズ株式会社 画像形成システム

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