DZ2845A1 - Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate. - Google Patents

Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.

Info

Publication number: DZ2845A1
Authority: DZ; Algeria
Prior art keywords: sulfonylü; aminoü; sobutyl; propylcarbamate; phosphonooxy
Prior art date: 1998-07-18

Application number

DZ990145A

Other languages

English (en)

French (fr)

Inventor

Lan Cordon Armitage

Andrew David Sealle

Hardev Singh

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-18

Filing date

1999-07-14

Publication date

2003-12-01

1999-07-14 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2003-12-01 Application granted granted Critical

2003-12-01 Publication of DZ2845A1 publication Critical patent/DZ2845A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DZ990145A 1998-07-18 1999-07-14 Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate. DZ2845A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9815567.4A GB9815567D0 (en)	1998-07-18	1998-07-18	Antiviral compound

Publications (1)

Publication Number	Publication Date
DZ2845A1 true DZ2845A1 (fr)	2003-12-01

Family

ID=10835689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ990145A DZ2845A1 (fr)	1998-07-18	1999-07-14	Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.

Country Status (48)

Country	Link
US (3)	US6514953B1 (da)
EP (2)	EP1098898B1 (da)
JP (1)	JP3437553B2 (da)
KR (1)	KR100694721B1 (da)
CN (1)	CN1188422C (da)
AP (1)	AP2001002039A0 (da)
AR (1)	AR019388A1 (da)
AT (1)	ATE229964T1 (da)
AU (1)	AU766056B2 (da)
BG (1)	BG105253A (da)
BR (1)	BRPI9912156B8 (da)
CA (1)	CA2337857C (da)
CO (1)	CO5090836A1 (da)
CZ (1)	CZ300447B6 (da)
DE (1)	DE69904600T2 (da)
DK (1)	DK1098898T3 (da)
DZ (1)	DZ2845A1 (da)
EA (1)	EA003191B1 (da)
EE (1)	EE200100038A (da)
ES (1)	ES2189450T3 (da)
GB (1)	GB9815567D0 (da)
GC (1)	GC0000105A (da)
GE (1)	GEP20033030B (da)
GT (1)	GT199900111A (da)
HK (1)	HK1034261A1 (da)
HR (1)	HRP20010046A2 (da)
HU (1)	HU229700B1 (da)
ID (1)	ID28070A (da)
IL (1)	IL140824A (da)
IS (1)	IS5808A (da)
JO (1)	JO2114B1 (da)
MA (1)	MA26660A1 (da)
MY (1)	MY122323A (da)
NO (1)	NO329676B1 (da)
NZ (1)	NZ509291A (da)
OA (1)	OA11706A (da)
PA (1)	PA8477801A1 (da)
PE (1)	PE20000869A1 (da)
PL (1)	PL195736B1 (da)
PT (1)	PT1098898E (da)
SK (1)	SK285311B6 (da)
SV (1)	SV1999000096A (da)
TN (1)	TNSN99145A1 (da)
TR (1)	TR200100111T2 (da)
TW (1)	TWI245770B (da)
WO (1)	WO2000004033A1 (da)
YU (1)	YU3401A (da)
ZA (1)	ZA200100417B (da)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9914821D0 (en) *	1999-06-24	1999-08-25	Glaxo Group Ltd	Compounds
DK1222192T3 (da) *	1999-10-06	2008-10-20	Tibotec Pharm Ltd	Hexahydrofuro-2,3-b furan-3-yl-N-3-(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino-1-benzyl-2-hydroxypropyl-carbamat som retroviral proteaseinhibitor
EP1226138B1 (en) *	1999-10-08	2004-12-29	Affinium Pharmaceuticals, Inc.	Fab i inhibitors
US7049310B2 (en) *	2001-04-06	2006-05-23	Affinium Pharmaceuticals, Inc.	Fab I inhibitors
JP2005523922A (ja)	2002-04-26	2005-08-11	ギリアードサイエンシーズ，インコーポレイテッド	非ヌクレオシド逆転写酵素阻害剤
DK1575951T3 (da) *	2002-12-06	2014-09-15	Debiopharm Int Sa	Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi
CA2519429C (en)	2003-03-17	2013-08-06	Affinium Pharmaceuticals, Inc.	Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
ATE490788T1 (de)	2003-04-25	2010-12-15	Gilead Sciences Inc	Antivirale phosphonate analoge
US7470724B2 (en)	2003-04-25	2008-12-30	Gilead Sciences, Inc.	Phosphonate compounds having immuno-modulatory activity
US7432261B2 (en)	2003-04-25	2008-10-07	Gilead Sciences, Inc.	Anti-inflammatory phosphonate compounds
WO2005002626A2 (en)	2003-04-25	2005-01-13	Gilead Sciences, Inc.	Therapeutic phosphonate compounds
WO2004096287A2 (en)	2003-04-25	2004-11-11	Gilead Sciences, Inc.	Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
CA2522845A1 (en)	2003-04-25	2004-11-11	Gilead Sciences, Inc.	Kinase inhibitor phosphonate conjugates
US7407965B2 (en)	2003-04-25	2008-08-05	Gilead Sciences, Inc.	Phosphonate analogs for treating metabolic diseases
US7452901B2 (en)	2003-04-25	2008-11-18	Gilead Sciences, Inc.	Anti-cancer phosphonate analogs
WO2004096285A2 (en)	2003-04-25	2004-11-11	Gilead Sciences, Inc.	Anti-infective phosphonate conjugates
PT1670448E (pt) *	2003-09-30	2008-02-11	Tibotec Pharm Ltd	Sulfonamidas inibidoras de hcv
EP1680512A1 (en)	2003-10-24	2006-07-19	Gilead Sciences, Inc.	Methods and compositions for identifying therapeutic compounds
WO2005044279A1 (en)	2003-10-24	2005-05-19	Gilead Sciences, Inc.	Purine nucleoside phosphonate conjugates
WO2005044308A1 (en)	2003-10-24	2005-05-19	Gilead Sciences, Inc.	Phosphonate analogs of antimetabolites
KR20060127906A (ko)	2003-12-22	2006-12-13	길리애드 사이언시즈, 인코포레이티드	4'-치환된 카보버와 아바카비어 유도체 및 ｈｉｖ와 ｈｃｖ항바이러스 활성을 갖는 관련 화합물
DK1828167T3 (da) *	2004-06-04	2014-10-20	Debiopharm Int Sa	Acrylamidderivater som antibiotiske midler
EP1778251B1 (en)	2004-07-27	2011-04-13	Gilead Sciences, Inc.	Nucleoside phosphonate conjugates as anti hiv agents
ES2341120T3 (es)	2004-11-26	2010-06-15	Ucl Business Plc	Composiciones que comprenden ornitina y fenilacetato o fenilbutirato para tratar encefalopatia hepatica.
JP2009518399A (ja) *	2005-12-05	2009-05-07	アフィニウムファーマシューティカルズ，インク．	Ｆａｂｉ阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
EP2687533B1 (en)	2006-07-20	2017-07-19	Debiopharm International SA	Acrylamide derivatives as FAB I inhibitors
US8263613B2 (en) *	2007-02-16	2012-09-11	Affinium Pharmaceuticals, Inc.	Salts, prodrugs and polymorphs of fab I inhibitors
CN102816111B (zh)	2007-03-12	2014-08-06	尼克塔治疗公司	低聚物-蛋白酶抑制剂偶联物
US9095620B2 (en) *	2008-03-12	2015-08-04	Nektar Therapeutics	Reagents
ES2393962T3 (es)	2008-07-08	2013-01-03	Gilead Sciences, Inc.	Sales de compuestos inhibidores del VIH.
CA2998344C (en)	2009-04-03	2020-06-02	Ocera Therapeutics, Inc.	L-ornithine phenyl acetate and methods of making thereof
EP2432788A1 (en) *	2009-05-20	2012-03-28	Ranbaxy Laboratories Limited	Amorphous fosamprenavir calcium
MX2011013129A (es)	2009-06-08	2012-03-14	Ucl Business Plc	Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.
WO2010144869A2 (en)	2009-06-12	2010-12-16	Nektar Therapeutics	Protease inhibitors
EP2448949A1 (en) *	2009-06-30	2012-05-09	Ranbaxy Laboratories Limited	Crystalline form of fosamprenavir calcium
EP2477996A1 (en)	2009-09-16	2012-07-25	Ranbaxy Laboratories Limited	Process for the preparation of fosamprenavir calcium
WO2011085130A1 (en) *	2010-01-07	2011-07-14	Pliva Hrvatska D.O.O.	Solid state forms of fosamprenavir calcium salt and process for preparation thereof
DK3127542T3 (da)	2010-01-27	2018-11-12	Viiv Healthcare Co	Antiviral terapi
US20110224443A1 (en) *	2010-03-15	2011-09-15	Venkata Naga Brahmeshwara Rao Mandava	Preparation of fosamprenavir calcium
WO2011114212A1 (en)	2010-03-19	2011-09-22	Lupin Limited	Ammonium, calcium and tris salts of fosamprenavir
WO2011158259A1 (en) *	2010-06-18	2011-12-22	Matrix Laboratories Ltd	Novel process for the preparation of (3s)-tetrahydrofuran-3-yl (is, 2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-(phosphonooxy) propylcarbamate and its pharmaceutically acceptable salts thereof
US8877947B2 (en)	2010-09-10	2014-11-04	Lupin Limited	Process for preparation of substantially pure fosamprenavir calcium and its intermediates
WO2012048043A1 (en)	2010-10-06	2012-04-12	Ocera Therapeutics, Inc.	Methods of making l-ornithine phenyl acetate
CN102453054B (zh) *	2010-10-29	2015-06-10	浙江九洲药业股份有限公司	一种福沙那韦衍生物的制备方法及相关中间体
CN102453053B (zh) *	2010-10-29	2014-11-26	浙江九洲药业股份有限公司	一种福沙那韦钙晶体及其制备方法
WO2012085625A1 (en)	2010-12-21	2012-06-28	Lupin Limited	Process for the preparation of fosamprenavir calcium and intermediate used in its preparation
US8993786B2 (en)	2011-02-10	2015-03-31	Mylan Laboratories Ltd.	Crystalline fosamprenavir calcium and process for the preparation thereof
WO2013011485A1 (en)	2011-07-20	2013-01-24	Ranbaxy Laboratories Limited	Process for the preparation of sulfonamides useful as retroviral protease inhibitors
WO2013105118A1 (en)	2012-01-10	2013-07-18	Council Of Scientific & Industrial Research	A process for synthesis of syn azido epoxide and its use as intermediate the synthesis of amprenavir & saquinavir
EP2861608B8 (en)	2012-06-19	2019-06-19	Debiopharm International SA	Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
AU2015353703B2 (en)	2014-11-24	2021-04-01	Ucl Business Plc	Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
JP6990170B2 (ja)	2015-08-18	2022-01-12	オセラセラピューティクス，インコーポレイテッド	Ｌ－オルニチンをフェニルアセテートおよびフェニルブチレートのうちの少なくとも１つと組み合わせて用いる筋肉喪失の治療および予防
MY189221A (en)	2016-02-26	2022-01-31	Debiopharm Int Sa	Medicament for treatment of diabetic foot infections
JP7126520B2 (ja)	2017-05-11	2022-08-26	オセラセラピューティクス，インコーポレイテッド	Ｌ－オルニチンフェニルアセテートを製造する方法
PT3661937T (pt)	2017-08-01	2021-09-24	Gilead Sciences Inc	Formas cristalinas de ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-il)-4-fluoro-2,5-dihidrofurano-2-il)oxi)metil)(fenoxi)fosforil)-l-alaninato de etil (gs-9131) para tratamento de infeções virais

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2698826A (en) *	1951-02-13	1955-01-04	Merco Centrifugal Co	Alcohol manufacturing process
US3437267A (en) *	1966-03-24	1969-04-08	Alfa Laval Ab	Centrifuge
JPH0244315B2 (ja) *	1982-06-14	1990-10-03	Microbial Chem Res Found	Supagarinn155hosufueetooyobisonoseizoho
US5723490A (en) *	1992-09-08	1998-03-03	Vertex Pharmaceuticals Incorporated	THF-containing sulfonamide inhibitors of aspartyl protease
UA49803C2 (uk) *	1994-06-03	2002-10-15	Дж.Д. Сьорль Енд Ко	Спосіб лікування ретровірусних інфекцій
US6436989B1 (en) *	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
SK9672000A3 (en) *	1997-12-24	2001-04-09	Vertex Pharmaceuticals Inc Ver	Prodrugs of aspartyl protease inhibitors
AU2010299A (en) *	1997-12-24	1999-07-19	Vertex Pharmaceuticals Incorporated	Prodrugs os aspartyl protease inhibitors
GB9812189D0 (en) *	1998-06-05	1998-08-05	Glaxo Group Ltd	Methods and compositions for increasing penetration of HIV protease inhibitors
AU6329599A (en) *	1998-09-28	2000-04-17	Glaxo Group Limited	Antiviral combinations comprising (s)-2-ethyl -7-fluoro -3-oxo-3, 4-dihydro -2h-quinoxaline -1-carboxylic acid isopropyl ester
WO2000025784A1 (en) *	1998-11-04	2000-05-11	Pharmacia & Upjohn Company	Method for improving the pharmacokinetics of tipranavir
CZ20002364A3 (cs) *	1998-12-23	2000-11-15	Vertex Pharmaceuticals Incorporated	Deriváty sulfonamidů a farmaceutický prostředek, který je obsahuje
GB9914821D0 (en) *	1999-06-24	1999-08-25	Glaxo Group Ltd	Compounds
ES2295068T3 (es) *	1999-11-24	2008-04-16	MERCK & CO., INC.	Gamma-hidroxi-2-(fluoroalquilaminocarbonil)-1-piperazinpentanamidas como inhibidores de la proteasa del vih.

1998
- 1998-07-18 GB GBGB9815567.4A patent/GB9815567D0/en not_active Ceased
1999
- 1999-07-14 AR ARP990103446A patent/AR019388A1/es not_active Application Discontinuation
- 1999-07-14 DZ DZ990145A patent/DZ2845A1/xx active
- 1999-07-14 GC GCP1999203 patent/GC0000105A/xx active
- 1999-07-15 ES ES99934698T patent/ES2189450T3/es not_active Expired - Lifetime
- 1999-07-15 WO PCT/EP1999/004991 patent/WO2000004033A1/en active IP Right Grant
- 1999-07-15 GE GEAP19995716A patent/GEP20033030B/en unknown
- 1999-07-15 TR TR2001/00111T patent/TR200100111T2/xx unknown
- 1999-07-15 SV SV1999000096A patent/SV1999000096A/es not_active Application Discontinuation
- 1999-07-15 EP EP99934698A patent/EP1098898B1/en not_active Expired - Lifetime
- 1999-07-15 PE PE1999000714A patent/PE20000869A1/es not_active Application Discontinuation
- 1999-07-15 HU HU0103432A patent/HU229700B1/hu unknown
- 1999-07-15 YU YU3401A patent/YU3401A/sh unknown
- 1999-07-15 GT GT199900111A patent/GT199900111A/es unknown
- 1999-07-15 AU AU50379/99A patent/AU766056B2/en not_active Expired
- 1999-07-15 CZ CZ20010219A patent/CZ300447B6/cs not_active IP Right Cessation
- 1999-07-15 OA OA1200100016A patent/OA11706A/fr unknown
- 1999-07-15 DE DE69904600T patent/DE69904600T2/de not_active Expired - Lifetime
- 1999-07-15 KR KR1020017000740A patent/KR100694721B1/ko not_active IP Right Cessation
- 1999-07-15 CO CO99044882A patent/CO5090836A1/es unknown
- 1999-07-15 EE EEP200100038A patent/EE200100038A/xx unknown
- 1999-07-15 JO JO19992114A patent/JO2114B1/en active
- 1999-07-15 SK SK76-2001A patent/SK285311B6/sk not_active IP Right Cessation
- 1999-07-15 CN CNB998108383A patent/CN1188422C/zh not_active Expired - Lifetime
- 1999-07-15 NZ NZ509291A patent/NZ509291A/en not_active IP Right Cessation
- 1999-07-15 DK DK99934698T patent/DK1098898T3/da active
- 1999-07-15 EP EP02013136A patent/EP1240903A3/en not_active Withdrawn
- 1999-07-15 EA EA200100053A patent/EA003191B1/ru not_active IP Right Cessation
- 1999-07-15 CA CA2337857A patent/CA2337857C/en not_active Expired - Lifetime
- 1999-07-15 JP JP2000560139A patent/JP3437553B2/ja not_active Expired - Lifetime
- 1999-07-15 MA MA25684A patent/MA26660A1/fr unknown
- 1999-07-15 ID IDW20010145A patent/ID28070A/id unknown
- 1999-07-15 PT PT99934698T patent/PT1098898E/pt unknown
- 1999-07-15 IL IL14082499A patent/IL140824A/en not_active IP Right Cessation
- 1999-07-15 PL PL99345620A patent/PL195736B1/pl unknown
- 1999-07-15 TN TNTNSN99145A patent/TNSN99145A1/fr unknown
- 1999-07-15 AP APAP/P/2001/002039A patent/AP2001002039A0/en unknown
- 1999-07-15 BR BRPI9912156A patent/BRPI9912156B8/pt not_active IP Right Cessation
- 1999-07-15 MY MYPI99002983A patent/MY122323A/en unknown
- 1999-07-15 US US09/744,051 patent/US6514953B1/en not_active Expired - Lifetime
- 1999-07-15 AT AT99934698T patent/ATE229964T1/de active
- 1999-07-16 PA PA19998477801A patent/PA8477801A1/es unknown
- 1999-08-06 TW TW088113428A patent/TWI245770B/zh not_active IP Right Cessation
2001
- 2001-01-12 IS IS5808A patent/IS5808A/is unknown
- 2001-01-15 ZA ZA200100417A patent/ZA200100417B/en unknown
- 2001-01-17 NO NO20010282A patent/NO329676B1/no not_active IP Right Cessation
- 2001-01-17 HR HR20010046A patent/HRP20010046A2/hr not_active Application Discontinuation
- 2001-02-14 BG BG105253A patent/BG105253A/xx unknown
- 2001-07-13 HK HK01104903A patent/HK1034261A1/xx not_active IP Right Cessation
2002
- 2002-11-25 US US10/303,366 patent/US20030096795A1/en not_active Abandoned
- 2002-11-25 US US10/303,213 patent/US20030100537A1/en not_active Abandoned

Also Published As

Publication number	Publication date
GEP20033030B (en)	2003-07-25
DE69904600T2 (de)	2003-11-13
GC0000105A (en)	2005-06-29
SK762001A3 (en)	2001-10-08
EP1240903A2 (en)	2002-09-18
GT199900111A (es)	2001-01-05
ID28070A (id)	2001-05-03
AR019388A1 (es)	2002-02-13
TNSN99145A1 (fr)	2005-11-10
GB9815567D0 (en)	1998-09-16
NO20010282D0 (no)	2001-01-17
NZ509291A (en)	2003-05-30
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JP3437553B2 (ja)	2003-08-18
EP1098898B1 (en)	2002-12-18
BRPI9912156B1 (pt)	2016-07-26
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US20030100537A1 (en)	2003-05-29
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EP1098898A1 (en)	2001-05-16
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MY122323A (en)	2006-04-29
PL345620A1 (en)	2002-01-02
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BR9912156A (pt)	2001-04-10
DE69904600D1 (de)	2003-01-30
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Publication	Publication Date	Title
DZ2845A1 (fr)	2003-12-01	Calcium (3S) tétrahydro-3-furanyle(1S,2R)-3-ÄÄ(4-aminophényle)sulfonyleÜ(sobutyle)aminoÜ-1-benzyle-2(phosphonooxy)propylcarbamate.
DZ2738A1 (fr)	2003-12-01	Catalyseurs de polymérisation.
IT1303332B1 (it)	2000-11-06	Plantare pronosupinante per calzature.
DE59503106D1 (de)	1998-09-17	Hydrophile, hochquellfähige Hydrogele
NO963526D0 (no)	1996-08-23	N-metyl-N-[(1S)-1-fenyl-2-((3S)-3-hydroksypyrrolidin-1-yl)-etylÅ-2,2-difenylacetamid
NL1010854C2 (nl)	2000-06-23	Bedieningscilinder.
FR2763498B1 (fr)	1999-08-20	Endoscope, en particulier mediastinoscope
AU5818100A (en)	2001-01-31	Derivatives of (3s) tetrahydro-3-furanyl (1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzy -2-(phosphonooxy)propylcarbamate
NL1010255A1 (nl)	1999-04-08	Bollenplanter.
IT1304039B1 (it)	2001-03-02	Gommatore.
ES1033492Y (es)	1997-02-01	Mojon de limitacion vial, amovible.
SI1098898T1 (en)	2003-08-31	Calcium (3s) tetrahydro-3-furanyl(1s,2r)-3-(((4-aminophenyl) sulfonyl) (isobutyl) amino) -1-benzyl-2- (phosphonooxy) propylcarbamate
ES1036075Y (es)	1997-12-01	Consola.
ITTO980674A1 (it)	2000-01-31	Elicottero.
ES1030098Y (es)	1996-01-01	Tapa-casquillo nivelador, para somieres de ballestas.
ES1037688Y (es)	1998-11-01	Dispositivo de ayuda para la expectoracion, no invasivo.
ES1040568Y (es)	1999-08-16	Instrumento de escritura.
IT239134Y1 (it)	2001-02-19	Dispositivo aspirante, particolarmente per w.c.
ES1039404Y (es)	1999-05-16	Flauta de embolo transparente.
IT245540Y1 (it)	2002-03-22	Struttura di supporto, particolarmente per calzature.
ES1032283Y (es)	1996-10-16	Boligrafo de la suerte.
ES1039379Y (es)	1999-05-01	Bigudi retenedor de humedad.
ITBO980069A0 (it)	1998-02-11	Piattaforma rotante per autoveicoli.
TR199600863A3 (tr)	1998-05-21	Torako-lomber enstrüman seti.
ES1030157Y (es)	1996-01-16	Depresor lingual.