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DOP2015000150A - Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento - Google Patents

Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento

Info

Publication number
DOP2015000150A
DOP2015000150A DO2015000150A DO2015000150A DOP2015000150A DO P2015000150 A DOP2015000150 A DO P2015000150A DO 2015000150 A DO2015000150 A DO 2015000150A DO 2015000150 A DO2015000150 A DO 2015000150A DO P2015000150 A DOP2015000150 A DO P2015000150A
Authority
DO
Dominican Republic
Prior art keywords
tablets
during storage
good stability
stability during
improved acceptance
Prior art date
Application number
DO2015000150A
Other languages
English (en)
Inventor
Venkata-Rangarao Kanikanti
Hans-Jürgen Hamann
Georg Schulte
Patrick Billian
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of DOP2015000150A publication Critical patent/DOP2015000150A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A COMPRIMIDOS PARA ANIMALES QUE TIENEN UNA ACEPTACIÓN MEJORADA Y BUENA ESTABILIDAD DURANTE EL ALMACENAMIENTO.
DO2015000150A 2012-12-19 2015-06-15 Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento DOP2015000150A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12198101 2012-12-19

Publications (1)

Publication Number Publication Date
DOP2015000150A true DOP2015000150A (es) 2015-07-15

Family

ID=47458712

Family Applications (2)

Application Number Title Priority Date Filing Date
DO2015000150A DOP2015000150A (es) 2012-12-19 2015-06-15 Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento
DO2020000031A DOP2020000031A (es) 2012-12-19 2020-02-10 Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento

Family Applications After (1)

Application Number Title Priority Date Filing Date
DO2020000031A DOP2020000031A (es) 2012-12-19 2020-02-10 Comprimidos que tienen aceptación mejorada y buena estabilidad durante el almacenamiento

Country Status (24)

Country Link
US (2) US10543170B2 (es)
EP (1) EP2934490B1 (es)
JP (1) JP6393274B2 (es)
KR (1) KR102253847B1 (es)
CN (1) CN105025885B (es)
AU (1) AU2013361760B2 (es)
CA (1) CA2895254C (es)
CL (1) CL2015001685A1 (es)
CR (1) CR20150321A (es)
DO (2) DOP2015000150A (es)
EC (1) ECSP15026203A (es)
ES (1) ES2848394T3 (es)
HK (1) HK1216856A1 (es)
IL (1) IL239297B (es)
MX (1) MX375182B (es)
MY (1) MY175703A (es)
NZ (1) NZ708741A (es)
PH (1) PH12015501390A1 (es)
PT (1) PT2934490T (es)
RU (1) RU2693005C2 (es)
SV (1) SV2015004997A (es)
UA (1) UA118748C2 (es)
WO (1) WO2014095845A1 (es)
ZA (1) ZA201505170B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102253847B1 (ko) * 2012-12-19 2021-05-21 바이엘 애니멀 헬스 게엠베하 향상된 수용성 및 우수한 저장 안정성을 가지는 정제
CN106580896A (zh) * 2016-12-07 2017-04-26 成都乾坤动物药业股份有限公司 一种非班太尔分散片及其制备方法
WO2018104150A1 (en) * 2016-12-09 2018-06-14 Bayer Animal Health Gmbh Pharmaceutical preparation and method for its manufacture
JP7241170B2 (ja) * 2018-09-05 2023-03-16 ゾエティス・サービシーズ・エルエルシー 食味の良い抗寄生虫製剤

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5746986A (en) 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4670444B1 (en) 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
US4472405A (en) 1982-11-12 1984-09-18 Riker Laboratories, Inc. Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives
US4730000A (en) 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
AT392789B (de) 1985-01-23 1991-06-10 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten
IN166416B (es) 1985-09-18 1990-05-05 Pfizer
DE3705227A1 (de) 1987-02-19 1988-09-01 Bayer Ag Anthelminthische wirkstoffkombinationen
FR2715803B3 (fr) 1994-02-04 1996-05-10 Attali Jean Claude Leurre et procédé facilitant la prise de médicaments par certains animaux et en particulier par les chiens.
DE670160T1 (de) 1994-03-01 1996-03-14 Gergely, Gerhard, Dr., Wien Ein Brausesystem und einen Arzneiwirkstoff enthaltendes granuläres Produkt bzw. Tablette sowie Verfahren zu deren Herstellung.
DE19520275A1 (de) 1995-06-02 1996-12-05 Bayer Ag Endoparasitizide Mittel
US20040180034A1 (en) 2003-03-10 2004-09-16 Lyn Hughes Anthelmintic resinates and a method for their preparation
DE10328666A1 (de) 2003-06-26 2005-01-13 Bayer Healthcare Ag Tabletten enthaltend Geschmacks-und/oder Aromastoffe
AR045142A1 (es) * 2003-07-30 2005-10-19 Novartis Ag Composicion veterinaria masticable ductil de buen sabor
GB2407498B (en) 2003-10-30 2008-06-11 Cipla Ltd Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
DE102004011512B4 (de) * 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
US7348027B2 (en) 2005-04-08 2008-03-25 Bayer Healthcare Llc Taste masked veterinary formulation
JP2007269716A (ja) * 2006-03-31 2007-10-18 Sato Pharmaceutical Co Ltd 塩酸セチリジン含有粒子
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
JP5296456B2 (ja) * 2008-08-26 2013-09-25 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
WO2010132286A1 (en) 2009-05-12 2010-11-18 Wyeth Llc Orally administered tablet formulation of an antianxiolytic compound
GB2475701B (en) * 2009-11-26 2011-10-19 Michael Hilary Burke A process for the preparation of an orally administered anthelmintic unit dose tablet
BR112013008834B1 (pt) 2010-10-12 2021-08-03 Bayer Intellectual Property Gmbh Produto mastigável macio e seu processo de preparação
RU2763496C2 (ru) * 2012-02-06 2021-12-29 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Паразитицидные пероральные ветеринарные композиции, включающие системно действующие активные агенты, способы и применение этих композиций и способов
KR102253847B1 (ko) * 2012-12-19 2021-05-21 바이엘 애니멀 헬스 게엠베하 향상된 수용성 및 우수한 저장 안정성을 가지는 정제
GB201413832D0 (en) * 2014-08-05 2014-09-17 Tate & Lyle Ingredients Starch compositions useful for thickening aqueous liquids

Also Published As

Publication number Publication date
HK1216856A1 (zh) 2016-12-09
US11147764B2 (en) 2021-10-19
MX375182B (es) 2025-03-06
IL239297B (en) 2021-10-31
AU2013361760B2 (en) 2018-07-05
NZ708741A (en) 2019-11-29
JP2016503767A (ja) 2016-02-08
EP2934490A1 (de) 2015-10-28
EP2934490B1 (de) 2020-08-12
KR20150094643A (ko) 2015-08-19
CA2895254C (en) 2021-01-26
CL2015001685A1 (es) 2015-10-23
PT2934490T (pt) 2020-12-15
WO2014095845A1 (de) 2014-06-26
RU2015129310A (ru) 2017-01-24
KR102253847B1 (ko) 2021-05-21
CN105025885B (zh) 2022-04-08
US10543170B2 (en) 2020-01-28
ES2848394T3 (es) 2021-08-09
US20200113823A1 (en) 2020-04-16
JP6393274B2 (ja) 2018-09-19
CR20150321A (es) 2015-07-29
SV2015004997A (es) 2017-05-12
US20150342889A1 (en) 2015-12-03
MX2015007640A (es) 2015-09-23
DOP2020000031A (es) 2020-02-28
IL239297A0 (en) 2015-07-30
RU2693005C2 (ru) 2019-07-01
ZA201505170B (en) 2025-02-26
CN105025885A (zh) 2015-11-04
UA118748C2 (uk) 2019-03-11
CA2895254A1 (en) 2014-06-26
PH12015501390A1 (en) 2015-09-02
ECSP15026203A (es) 2016-01-29
AU2013361760A1 (en) 2015-07-09
MY175703A (en) 2020-07-06

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