DK514989D0 - Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler - Google Patents

Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler

Info

Publication number: DK514989D0
Authority: DK; Denmark
Prior art keywords: enolesters; oxindol; carboxamides; acyl; ethers
Prior art date: 1988-10-18

Application number

DK514989A

Other languages

English (en)

Other versions

DK514989A (da

Inventor

Thomas Charles Crawford

Lawrence Alan Reiter

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-18

Filing date

1989-10-17

Publication date

1989-10-17

1989-10-17 Application filed by Pfizer filed Critical Pfizer

1989-10-17 Publication of DK514989D0 publication Critical patent/DK514989D0/da

1990-04-19 Publication of DK514989A publication Critical patent/DK514989A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Rheumatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK514989A 1988-10-18 1989-10-17 Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler DK514989A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1988/003658 WO1990004393A1 (en)	1988-10-18	1988-10-18	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Publications (2)

Publication Number	Publication Date
DK514989D0 true DK514989D0 (da)	1989-10-17
DK514989A DK514989A (da)	1990-04-19

Family

ID=22208957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK514989A DK514989A (da)	1988-10-18	1989-10-17	Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler

Country Status (33)

Country	Link
US (1)	US5118703A (da)
JP (1)	JPH07597B2 (da)
KR (1)	KR910007237B1 (da)
CN (1)	CN1022241C (da)
AP (1)	AP118A (da)
AR (1)	AR246519A1 (da)
AT (1)	ATE125794T1 (da)
AU (1)	AU606819B2 (da)
BG (1)	BG50834A3 (da)
CA (1)	CA1339558C (da)
CZ (1)	CZ278983B6 (da)
DD (1)	DD285604A5 (da)
DK (1)	DK514989A (da)
EG (1)	EG19887A (da)
FI (1)	FI95253C (da)
HU (1)	HU208421B (da)
IE (1)	IE66586B1 (da)
IL (1)	IL91960A (da)
IS (1)	IS1598B (da)
MA (1)	MA21657A1 (da)
MX (1)	MX18021A (da)
MY (1)	MY104238A (da)
NO (1)	NO178027C (da)
NZ (1)	NZ231044A (da)
OA (1)	OA09140A (da)
PH (1)	PH27554A (da)
PL (2)	PL163112B1 (da)
PT (1)	PT92000B (da)
RO (1)	RO109195B1 (da)
RU (1)	RU2036905C1 (da)
SK (1)	SK278175B6 (da)
WO (1)	WO1990004393A1 (da)
YU (1)	YU48070B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5059693A (en) *	1989-10-06	1991-10-22	Pfizer Inc.	Process for making 3-aroyl-2-oxindole-1-carboxamides
CZ131695A3 (en) *	1992-11-23	1996-05-15	Pfizer	Process for preparing 4-chloro-2-thiophenecarboxylic acid, intermediates for its preparation and process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide
US5270331A (en) *	1993-01-26	1993-12-14	Pfizer, Inc.	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
JP2709530B2 (ja) *	1993-02-09	1998-02-04	ファイザー・インク．	抗炎症薬としてのオキシンドール１−［ｎ−（アルコキシカルボニル）］カルボキサミド類および１−（ｎ−カルボキサミド）カルボキサミド類
US5449788A (en) *	1994-01-28	1995-09-12	Catalytica, Inc.	Process for preparing 2-oxindole-1-carboxamides
CN1094819C (zh) *	1997-04-30	2002-11-27	大兴株式会社	环状坯料之制造装置
EP0984012A3 (en) *	1998-08-31	2001-01-10	Pfizer Products Inc.	Nitric oxide releasing oxindole prodrugs with analgesic and anti-inflammatory properties
CA2386889A1 (en) *	1999-10-26	2001-05-03	The University Of Texas Southwestern Medical Center	Methods of treating hair loss comprising administering indoline compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL96047C (da) *	1956-06-08
US3564009A (en) *	1966-01-13	1971-02-16	Sumitomo Chemical Co	Process for producing 1-acylindole derivatives
BE756447A (fr) *	1969-10-15	1971-03-22	Pfizer	Oxindolecarboxamides
US3923996A (en) *	1972-07-31	1975-12-02	Sandoz Ag	3-Substituted-oxindoles in compositions and methods of treating obesity
IE53102B1 (en) *	1981-05-12	1988-06-22	Ici Plc	Pharmaceutical spiro-succinimide derivatives
DE3268971D1 (en) *	1981-10-06	1986-03-20	Ici Plc	Biochemical process
US4556672A (en) *	1984-03-19	1985-12-03	Pfizer Inc.	3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4752609A (en) *	1985-06-20	1988-06-21	Pfizer Inc.	Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
WO1988005656A1 (en) *	1987-02-02	1988-08-11	Pfizer Inc.	Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide
DE68923673T2 (de) *	1988-10-18	1996-01-18	Pfizer	Prodrogen von antiinflammatorischen 3-Acyl-2-oxindol-1-carboxamiden.
US5047554A (en) *	1989-04-18	1991-09-10	Pfizer Inc.	3-substituted-2-oxindole derivatives
US5059693A (en) *	1989-10-06	1991-10-22	Pfizer Inc.	Process for making 3-aroyl-2-oxindole-1-carboxamides

1988
- 1988-10-18 HU HU886740A patent/HU208421B/hu not_active IP Right Cessation
- 1988-10-18 SK SK5906-89A patent/SK278175B6/sk unknown
- 1988-10-18 RO RO147347A patent/RO109195B1/ro unknown
- 1988-10-18 US US07/675,883 patent/US5118703A/en not_active Expired - Lifetime
- 1988-10-18 MX MX1802188A patent/MX18021A/es unknown
- 1988-10-18 WO PCT/US1988/003658 patent/WO1990004393A1/en active IP Right Grant
1989
- 1989-09-20 IS IS3509A patent/IS1598B/is unknown
- 1989-09-28 CA CA000614317A patent/CA1339558C/en not_active Expired - Fee Related
- 1989-10-04 PH PH39329A patent/PH27554A/en unknown
- 1989-10-09 AT AT89310319T patent/ATE125794T1/de active
- 1989-10-12 IL IL9196089A patent/IL91960A/xx not_active IP Right Cessation
- 1989-10-16 PT PT92000A patent/PT92000B/pt not_active IP Right Cessation
- 1989-10-16 MY MYPI89001415A patent/MY104238A/en unknown
- 1989-10-16 BG BG090022A patent/BG50834A3/xx unknown
- 1989-10-16 AP APAP/P/1989/000141A patent/AP118A/en active
- 1989-10-16 YU YU200589A patent/YU48070B/sh unknown
- 1989-10-17 MA MA21909A patent/MA21657A1/fr unknown
- 1989-10-17 CN CN89107943A patent/CN1022241C/zh not_active Expired - Fee Related
- 1989-10-17 PL PL89296831A patent/PL163112B1/pl unknown
- 1989-10-17 IE IE333289A patent/IE66586B1/en not_active IP Right Cessation
- 1989-10-17 DK DK514989A patent/DK514989A/da not_active Application Discontinuation
- 1989-10-17 AR AR89315179A patent/AR246519A1/es active
- 1989-10-17 NZ NZ231044A patent/NZ231044A/en unknown
- 1989-10-17 PL PL89281871A patent/PL162316B1/pl unknown
- 1989-10-17 OA OA59665A patent/OA09140A/xx unknown
- 1989-10-17 DD DD89333653A patent/DD285604A5/de not_active IP Right Cessation
- 1989-10-17 KR KR1019890014914A patent/KR910007237B1/ko not_active IP Right Cessation
- 1989-10-17 AU AU42956/89A patent/AU606819B2/en not_active Ceased
- 1989-10-17 JP JP1270174A patent/JPH07597B2/ja not_active Expired - Lifetime
- 1989-10-18 EG EG49689A patent/EG19887A/xx active
- 1989-10-18 CZ CS895906A patent/CZ278983B6/cs not_active IP Right Cessation
1991
- 1991-04-17 FI FI911855A patent/FI95253C/fi not_active IP Right Cessation
- 1991-04-17 RU SU914895525A patent/RU2036905C1/ru active
- 1991-04-17 NO NO911512A patent/NO178027C/no unknown

Also Published As

Publication number	Publication date
RU2036905C1 (ru)	1995-06-09
PH27554A (en)	1993-08-18
IS1598B (is)	1996-05-20
SK590689A3 (en)	1996-03-06
HU208421B (en)	1993-10-28
NO178027C (no)	1996-01-10
OA09140A (fr)	1991-10-31
YU200589A (en)	1991-02-28
AU4295689A (en)	1990-04-26
YU48070B (sh)	1997-01-08
CZ278983B6 (en)	1994-11-16
DD285604A5 (de)	1990-12-19
JPH07597B2 (ja)	1995-01-11
CN1022241C (zh)	1993-09-29
KR900006285A (ko)	1990-05-07
PL163112B1 (pl)	1994-02-28
MX18021A (es)	1993-11-01
CA1339558C (en)	1997-11-25
NO178027B (no)	1995-10-02
IE66586B1 (en)	1996-01-24
JPH02149559A (ja)	1990-06-08
IL91960A0 (en)	1990-07-12
IS3509A7 (is)	1990-04-19
MY104238A (en)	1994-02-28
PL162316B1 (pl)	1993-09-30
CZ590689A3 (en)	1994-04-13
AP118A (en)	1991-02-22
EG19887A (en)	1996-03-31
HU886740D0 (en)	1991-07-29
NO911512D0 (no)	1991-04-17
PT92000A (pt)	1990-04-30
CN1041938A (zh)	1990-05-09
RO109195B1 (ro)	1994-12-30
PT92000B (pt)	1995-06-30
FI95253C (fi)	1996-01-10
AR246519A1 (es)	1994-08-31
US5118703A (en)	1992-06-02
KR910007237B1 (ko)	1991-09-24
SK278175B6 (en)	1996-03-06
WO1990004393A1 (en)	1990-05-03
FI95253B (fi)	1995-09-29
FI911855A0 (fi)	1991-04-17
AU606819B2 (en)	1991-02-14
ATE125794T1 (de)	1995-08-15
NO911512L (no)	1991-06-12
BG50834A3 (en)	1992-11-16
AP8900141A0 (en)	1989-10-31
DK514989A (da)	1990-04-19
HUT58052A (en)	1992-01-28
IE893332L (en)	1990-04-18
NZ231044A (en)	1990-12-21
IL91960A (en)	1994-04-12
MA21657A1 (fr)	1990-07-01

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Legal Events

Date	Code	Title	Description
1999-07-19	AHB	Application shelved due to non-payment