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NO911512L - Forloepere for anti-inflammatoriske 3-acyl-2-oksindol-1-karboksamider - Google Patents

Forloepere for anti-inflammatoriske 3-acyl-2-oksindol-1-karboksamider

Info

Publication number
NO911512L
NO911512L NO91911512A NO911512A NO911512L NO 911512 L NO911512 L NO 911512L NO 91911512 A NO91911512 A NO 91911512A NO 911512 A NO911512 A NO 911512A NO 911512 L NO911512 L NO 911512L
Authority
NO
Norway
Prior art keywords
ocsindol
presidents
carboxamides
acyl
inflammatory
Prior art date
Application number
NO91911512A
Other languages
English (en)
Other versions
NO178027C (no
NO178027B (no
NO911512D0 (no
Inventor
Lawrence A Reiter
Thomas C Crawford
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO911512D0 publication Critical patent/NO911512D0/no
Publication of NO911512L publication Critical patent/NO911512L/no
Publication of NO178027B publication Critical patent/NO178027B/no
Publication of NO178027C publication Critical patent/NO178027C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO911512A 1988-10-18 1991-04-17 Analogifremgangsmåte ved fremstilling av forlöpere for anti-inflammatoriske 3-acyl-2-oksindol-1-karboksamider NO178027C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1988/003658 WO1990004393A1 (en) 1988-10-18 1988-10-18 Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Publications (4)

Publication Number Publication Date
NO911512D0 NO911512D0 (no) 1991-04-17
NO911512L true NO911512L (no) 1991-06-12
NO178027B NO178027B (no) 1995-10-02
NO178027C NO178027C (no) 1996-01-10

Family

ID=22208957

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911512A NO178027C (no) 1988-10-18 1991-04-17 Analogifremgangsmåte ved fremstilling av forlöpere for anti-inflammatoriske 3-acyl-2-oksindol-1-karboksamider

Country Status (33)

Country Link
US (1) US5118703A (no)
JP (1) JPH07597B2 (no)
KR (1) KR910007237B1 (no)
CN (1) CN1022241C (no)
AP (1) AP118A (no)
AR (1) AR246519A1 (no)
AT (1) ATE125794T1 (no)
AU (1) AU606819B2 (no)
BG (1) BG50834A3 (no)
CA (1) CA1339558C (no)
CZ (1) CZ278983B6 (no)
DD (1) DD285604A5 (no)
DK (1) DK514989A (no)
EG (1) EG19887A (no)
FI (1) FI95253C (no)
HU (1) HU208421B (no)
IE (1) IE66586B1 (no)
IL (1) IL91960A (no)
IS (1) IS1598B (no)
MA (1) MA21657A1 (no)
MX (1) MX18021A (no)
MY (1) MY104238A (no)
NO (1) NO178027C (no)
NZ (1) NZ231044A (no)
OA (1) OA09140A (no)
PH (1) PH27554A (no)
PL (2) PL163112B1 (no)
PT (1) PT92000B (no)
RO (1) RO109195B1 (no)
RU (1) RU2036905C1 (no)
SK (1) SK278175B6 (no)
WO (1) WO1990004393A1 (no)
YU (1) YU48070B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
CZ131695A3 (en) * 1992-11-23 1996-05-15 Pfizer Process for preparing 4-chloro-2-thiophenecarboxylic acid, intermediates for its preparation and process for preparing 5-fluoro-6-chloro-3-(4-chloro-2-thenoyl)-2-oxindole-1-carboxamide
US5270331A (en) * 1993-01-26 1993-12-14 Pfizer, Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
JP2709530B2 (ja) * 1993-02-09 1998-02-04 ファイザー・インク. 抗炎症薬としてのオキシンドール1−[n−(アルコキシカルボニル)]カルボキサミド類および1−(n−カルボキサミド)カルボキサミド類
US5449788A (en) * 1994-01-28 1995-09-12 Catalytica, Inc. Process for preparing 2-oxindole-1-carboxamides
CN1094819C (zh) * 1997-04-30 2002-11-27 大兴株式会社 环状坯料之制造装置
EP0984012A3 (en) * 1998-08-31 2001-01-10 Pfizer Products Inc. Nitric oxide releasing oxindole prodrugs with analgesic and anti-inflammatory properties
CA2386889A1 (en) * 1999-10-26 2001-05-03 The University Of Texas Southwestern Medical Center Methods of treating hair loss comprising administering indoline compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL96047C (no) * 1956-06-08
US3564009A (en) * 1966-01-13 1971-02-16 Sumitomo Chemical Co Process for producing 1-acylindole derivatives
BE756447A (fr) * 1969-10-15 1971-03-22 Pfizer Oxindolecarboxamides
US3923996A (en) * 1972-07-31 1975-12-02 Sandoz Ag 3-Substituted-oxindoles in compositions and methods of treating obesity
IE53102B1 (en) * 1981-05-12 1988-06-22 Ici Plc Pharmaceutical spiro-succinimide derivatives
DE3268971D1 (en) * 1981-10-06 1986-03-20 Ici Plc Biochemical process
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4752609A (en) * 1985-06-20 1988-06-21 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
WO1988005656A1 (en) * 1987-02-02 1988-08-11 Pfizer Inc. Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide
DE68923673T2 (de) * 1988-10-18 1996-01-18 Pfizer Prodrogen von antiinflammatorischen 3-Acyl-2-oxindol-1-carboxamiden.
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides

Also Published As

Publication number Publication date
RU2036905C1 (ru) 1995-06-09
PH27554A (en) 1993-08-18
IS1598B (is) 1996-05-20
SK590689A3 (en) 1996-03-06
HU208421B (en) 1993-10-28
NO178027C (no) 1996-01-10
OA09140A (fr) 1991-10-31
YU200589A (en) 1991-02-28
AU4295689A (en) 1990-04-26
YU48070B (sh) 1997-01-08
CZ278983B6 (en) 1994-11-16
DD285604A5 (de) 1990-12-19
JPH07597B2 (ja) 1995-01-11
CN1022241C (zh) 1993-09-29
KR900006285A (ko) 1990-05-07
PL163112B1 (pl) 1994-02-28
MX18021A (es) 1993-11-01
CA1339558C (en) 1997-11-25
NO178027B (no) 1995-10-02
IE66586B1 (en) 1996-01-24
JPH02149559A (ja) 1990-06-08
IL91960A0 (en) 1990-07-12
IS3509A7 (is) 1990-04-19
MY104238A (en) 1994-02-28
PL162316B1 (pl) 1993-09-30
CZ590689A3 (en) 1994-04-13
AP118A (en) 1991-02-22
DK514989D0 (da) 1989-10-17
EG19887A (en) 1996-03-31
HU886740D0 (en) 1991-07-29
NO911512D0 (no) 1991-04-17
PT92000A (pt) 1990-04-30
CN1041938A (zh) 1990-05-09
RO109195B1 (ro) 1994-12-30
PT92000B (pt) 1995-06-30
FI95253C (fi) 1996-01-10
AR246519A1 (es) 1994-08-31
US5118703A (en) 1992-06-02
KR910007237B1 (ko) 1991-09-24
SK278175B6 (en) 1996-03-06
WO1990004393A1 (en) 1990-05-03
FI95253B (fi) 1995-09-29
FI911855A0 (fi) 1991-04-17
AU606819B2 (en) 1991-02-14
ATE125794T1 (de) 1995-08-15
BG50834A3 (en) 1992-11-16
AP8900141A0 (en) 1989-10-31
DK514989A (da) 1990-04-19
HUT58052A (en) 1992-01-28
IE893332L (en) 1990-04-18
NZ231044A (en) 1990-12-21
IL91960A (en) 1994-04-12
MA21657A1 (fr) 1990-07-01

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