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DK3935047T3 - Fremgangsmåde til fremstilling af et substitueret imidazoquinolin - Google Patents

Fremgangsmåde til fremstilling af et substitueret imidazoquinolin Download PDF

Info

Publication number
DK3935047T3
DK3935047T3 DK20707669.6T DK20707669T DK3935047T3 DK 3935047 T3 DK3935047 T3 DK 3935047T3 DK 20707669 T DK20707669 T DK 20707669T DK 3935047 T3 DK3935047 T3 DK 3935047T3
Authority
DK
Denmark
Prior art keywords
preparation
substituted imidazoquinoline
imidazoquinoline
substituted
Prior art date
Application number
DK20707669.6T
Other languages
English (en)
Inventor
Christophe Henry
Original Assignee
BioNTech SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNTech SE filed Critical BioNTech SE
Application granted granted Critical
Publication of DK3935047T3 publication Critical patent/DK3935047T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/46Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK20707669.6T 2019-03-07 2020-03-06 Fremgangsmåde til fremstilling af et substitueret imidazoquinolin DK3935047T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2019055793 2019-03-07
PCT/EP2020/056047 WO2020178434A1 (en) 2019-03-07 2020-03-06 Process for the preparation of a substituted imidazoquinoline

Publications (1)

Publication Number Publication Date
DK3935047T3 true DK3935047T3 (da) 2024-09-09

Family

ID=69723965

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20707669.6T DK3935047T3 (da) 2019-03-07 2020-03-06 Fremgangsmåde til fremstilling af et substitueret imidazoquinolin

Country Status (18)

Country Link
US (1) US20220144822A1 (da)
EP (1) EP3935047B1 (da)
JP (1) JP7576038B2 (da)
KR (1) KR20210136033A (da)
CN (1) CN113518775B (da)
AU (1) AU2020231822A1 (da)
BR (1) BR112021016960A2 (da)
CA (1) CA3132229A1 (da)
CL (1) CL2021002322A1 (da)
CO (1) CO2021011258A2 (da)
CU (1) CU24679B1 (da)
DK (1) DK3935047T3 (da)
ES (1) ES2992926T3 (da)
IL (1) IL286054A (da)
MX (1) MX2021010669A (da)
PH (1) PH12021552106A1 (da)
SG (1) SG11202108752YA (da)
WO (1) WO2020178434A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023083439A1 (en) * 2021-11-09 2023-05-19 BioNTech SE Tlr7 agonist and combinations for cancer treatment

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451810B1 (en) 1999-06-10 2002-09-17 3M Innovative Properties Company Amide substituted imidazoquinolines
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
US6756382B2 (en) 1999-06-10 2004-06-29 3M Innovative Properties Company Amide substituted imidazoquinolines
US6677349B1 (en) 2001-12-21 2004-01-13 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
PE20040945A1 (es) * 2003-02-05 2004-12-14 Warner Lambert Co Preparacion de quinazolinas substituidas
WO2005051324A2 (en) 2003-11-25 2005-06-09 3M Innovative Properties Company Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
WO2008135791A1 (en) 2007-05-08 2008-11-13 Astrazeneca Ab Imidazoquinolines with immuno-modulating properties
RS53059B (en) 2008-03-24 2014-04-30 4Sc Discovery Gmbh NEW SUBSTITUTED IMIDAZOCHINOLINES
JP2013512859A (ja) 2009-12-03 2013-04-18 大日本住友製薬株式会社 トール様受容体(tlr)を介して作用するイミダゾキノリン
US8735386B2 (en) * 2010-07-23 2014-05-27 Boehringer Ingelheim International Gmbh Aminopyrazoloquinazolines
UA113280C2 (xx) * 2010-11-11 2017-01-10 АМІНОСПИРТЗАМІЩЕНІ ПОХІДНІ 2,3-ДИГІДРОІМІДАЗО$1,2-c]ХІНАЗОЛІНУ, ПРИДАТНІ ДЛЯ ЛІКУВАННЯ ГІПЕРПРОЛІФЕРАТИВНИХ ПОРУШЕНЬ І ЗАХВОРЮВАНЬ, ПОВ'ЯЗАНИХ З АНГІОГЕНЕЗОМ
CN108794467A (zh) 2017-04-27 2018-11-13 博笛生物科技有限公司 2-氨基-喹啉衍生物
WO2019048036A1 (en) * 2017-09-06 2019-03-14 Biontech Ag SUBSTITUTED IMIDAZOQUINOLINES
IL273039B2 (en) * 2017-09-06 2023-10-01 BioNTech SE Substituted imidazoquinolines as agonists of tlr7

Also Published As

Publication number Publication date
WO2020178434A1 (en) 2020-09-10
IL286054A (en) 2021-10-31
JP2022525023A (ja) 2022-05-11
EP3935047A1 (en) 2022-01-12
CU24679B1 (es) 2023-09-07
CO2021011258A2 (es) 2021-09-09
CU20210071A7 (es) 2022-04-07
SG11202108752YA (en) 2021-09-29
CL2021002322A1 (es) 2022-05-13
MX2021010669A (es) 2021-09-28
JP7576038B2 (ja) 2024-10-30
KR20210136033A (ko) 2021-11-16
US20220144822A1 (en) 2022-05-12
CA3132229A1 (en) 2020-09-10
CN113518775B (zh) 2024-10-29
CN113518775A (zh) 2021-10-19
ES2992926T3 (en) 2024-12-19
PH12021552106A1 (en) 2022-05-30
BR112021016960A2 (pt) 2021-11-23
AU2020231822A1 (en) 2021-08-26
EP3935047B1 (en) 2024-08-07

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