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FI20155554A - Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi - Google Patents

Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi

Info

Publication number
FI20155554A
FI20155554A FI20155554A FI20155554A FI20155554A FI 20155554 A FI20155554 A FI 20155554A FI 20155554 A FI20155554 A FI 20155554A FI 20155554 A FI20155554 A FI 20155554A FI 20155554 A FI20155554 A FI 20155554A
Authority
FI
Finland
Prior art keywords
nephrocystin
nphp1
recombinant
library
derivatives
Prior art date
Application number
FI20155554A
Other languages
English (en)
Swedish (sv)
Other versions
FI126633B (fi
Inventor
Kalle Saksela
Original Assignee
Next Biomed Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Next Biomed Therapies Oy filed Critical Next Biomed Therapies Oy
Priority to FI20155554A priority Critical patent/FI126633B/fi
Priority to PCT/FI2016/050509 priority patent/WO2017009533A1/en
Priority to EP21150093.9A priority patent/EP3851536A1/en
Priority to CA2991953A priority patent/CA2991953A1/en
Priority to US15/742,934 priority patent/US11060084B2/en
Priority to EP16741975.3A priority patent/EP3320095B1/en
Publication of FI20155554A publication Critical patent/FI20155554A/fi
Application granted granted Critical
Publication of FI126633B publication Critical patent/FI126633B/fi
Priority to US17/367,723 priority patent/US20210395726A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI20155554A 2015-07-10 2015-07-10 Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi FI126633B (fi)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FI20155554A FI126633B (fi) 2015-07-10 2015-07-10 Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi
PCT/FI2016/050509 WO2017009533A1 (en) 2015-07-10 2016-07-08 Sh3 domain derivatives
EP21150093.9A EP3851536A1 (en) 2015-07-10 2016-07-08 Sh3 domain derivatives
CA2991953A CA2991953A1 (en) 2015-07-10 2016-07-08 Sh3 domain derivatives
US15/742,934 US11060084B2 (en) 2015-07-10 2016-07-08 SH3 domain derivatives
EP16741975.3A EP3320095B1 (en) 2015-07-10 2016-07-08 Sh3 domain derivatives
US17/367,723 US20210395726A1 (en) 2015-07-10 2021-07-06 SH3 domain derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20155554A FI126633B (fi) 2015-07-10 2015-07-10 Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi

Publications (2)

Publication Number Publication Date
FI20155554A true FI20155554A (fi) 2017-01-11
FI126633B FI126633B (fi) 2017-03-15

Family

ID=56511599

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20155554A FI126633B (fi) 2015-07-10 2015-07-10 Menetelmä rekombinantteja nefrokystiinin (NPHP1) SH3-domeenin johdannaisia käsittävän kirjaston valmistamiseksi

Country Status (5)

Country Link
US (2) US11060084B2 (fi)
EP (2) EP3320095B1 (fi)
CA (1) CA2991953A1 (fi)
FI (1) FI126633B (fi)
WO (1) WO2017009533A1 (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12194157B2 (en) 2020-04-09 2025-01-14 Finncure Oy Carrier for targeted delivery to a host
AU2021252164A1 (en) 2020-04-09 2022-12-15 Finncure Oy Mimetic nanoparticles for preventing the spreading and lowering the infection rate of novel coronaviruses
CN113967257A (zh) * 2020-07-24 2022-01-25 上海交通大学医学院附属瑞金医院 一种c-Src SH3 RT-loop作为靶点用于抗血栓
WO2023089243A1 (en) * 2021-11-19 2023-05-25 Pandemblock Oy Sh3 domain derivatives targeting receptor binding domain (rbd) of sars-cov-2 spike protein

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2201870A1 (en) * 1994-10-07 1996-04-18 Kari Alitalo Cytoplasmic tyrosine kinase bmx protein and dna
WO1996031625A1 (en) * 1995-04-07 1996-10-10 Cytogen Corporation Polypeptides having a functional domain of interest and methods of identifying and using same
US6309820B1 (en) * 1995-04-07 2001-10-30 University Of North Carolina At Chapel Hill Polypeptides having a functional domain of interest and methods of identifying and using same
ES2371464T3 (es) 1999-05-26 2012-01-03 Next Biomed Technologies Nbt Oy Métodos y materiales para generar dominios sh3 con propiedades de unión seleccionadas.
GB0025804D0 (en) * 2000-10-20 2000-12-06 Glaxo Group Ltd Assay
WO2007030594A2 (en) * 2005-09-07 2007-03-15 Board Of Regents, The University Of Texas System Methods of using and analyzing biological sequence data
EP1892248A1 (en) * 2006-08-21 2008-02-27 Eidgenössische Technische Hochschule Zürich Specific and high affinity binding proteins comprising modified SH3 domains of FYN kinase
US9593314B2 (en) 2012-03-16 2017-03-14 Covagen Ag Binding molecules with antitumoral activity
CN105189544A (zh) 2013-04-19 2015-12-23 科瓦根股份公司 具有抗肿瘤活性的新颖的双特异性结合分子

Also Published As

Publication number Publication date
FI126633B (fi) 2017-03-15
US11060084B2 (en) 2021-07-13
EP3851536A1 (en) 2021-07-21
US20210395726A1 (en) 2021-12-23
CA2991953A1 (en) 2017-01-19
WO2017009533A1 (en) 2017-01-19
US20180230456A1 (en) 2018-08-16
EP3320095B1 (en) 2021-01-06
EP3320095A1 (en) 2018-05-16

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