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DK2732823T3 - Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte - Google Patents

Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte Download PDF

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Publication number
DK2732823T3
DK2732823T3 DK14154831.3T DK14154831T DK2732823T3 DK 2732823 T3 DK2732823 T3 DK 2732823T3 DK 14154831 T DK14154831 T DK 14154831T DK 2732823 T3 DK2732823 T3 DK 2732823T3
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DK
Denmark
Prior art keywords
trpv
pain
modulation
treatment
receptor system
Prior art date
Application number
DK14154831.3T
Other languages
English (en)
Inventor
Anders Nykjaer
Vægter Christian Bjerggaard
Ole Bjerrum
Pernille Jansen
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Application granted granted Critical
Publication of DK2732823T3 publication Critical patent/DK2732823T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK14154831.3T 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte DK2732823T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7562708P 2008-06-25 2008-06-25
DKPA200800880 2008-06-25
EP09768854.3A EP2307042B1 (en) 2008-06-25 2009-06-24 Modulation of the trpv : vps10p-domain receptor system for the treatment of pain

Publications (1)

Publication Number Publication Date
DK2732823T3 true DK2732823T3 (da) 2019-09-16

Family

ID=41445008

Family Applications (2)

Application Number Title Priority Date Filing Date
DK14154831.3T DK2732823T3 (da) 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte
DK09768854.3T DK2307042T3 (da) 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09768854.3T DK2307042T3 (da) 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte

Country Status (5)

Country Link
US (1) US8460657B2 (da)
EP (2) EP2307042B1 (da)
DK (2) DK2732823T3 (da)
ES (1) ES2464459T3 (da)
WO (1) WO2009155932A2 (da)

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LT3225251T (lt) 2006-12-21 2020-04-10 H. Lundbeck A/S Proneurotrofinų veiklos moduliavimas
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JP2013532144A (ja) * 2010-06-14 2013-08-15 ハー・ルンドベック・アクチエゼルスカベット ＳｏｒＬＡとＧＤＮＦファミリーリガンド受容体の間の相互作用の調節
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US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
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WO2014114779A1 (en) 2013-01-28 2014-07-31 H. Lundbeck A/S N-substituted-5-substituted phthalamic acids as sortilin inhibitors
DK3366677T3 (da) 2013-02-08 2020-09-28 Gen Mills Inc Fødevareprodukter med reduceret natriumindhold
PL3629026T3 (pl) * 2014-01-23 2021-08-02 Biogaia Ab Środki modulujące ból przewodu pokarmowego
EP3242893A1 (en) 2015-01-08 2017-11-15 Biogen MA Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
CN107708733B (zh) 2015-04-07 2022-11-15 艾利妥 抗分拣蛋白抗体和其使用方法
US10849992B1 (en) 2015-04-07 2020-12-01 Alector Llc Methods of screening for sortilin binding antagonists
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ES2940311T3 (es) 2018-07-13 2023-05-05 Alector Llc Anticuerpos anti-sortilina y métodos de uso de los mismos
CN117015375A (zh) * 2020-05-28 2023-11-07 福尔医学公司 用于治疗由冠状病毒引起的急性呼吸窘迫综合征(ards)和炎性病症的组合物和方法
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Also Published As

Publication number Publication date
DK2307042T3 (da) 2014-05-12
WO2009155932A3 (en) 2010-04-22
EP2732823B1 (en) 2019-08-07
US8460657B2 (en) 2013-06-11
EP2307042B1 (en) 2014-03-26
WO2009155932A2 (en) 2009-12-30
EP2307042A2 (en) 2011-04-13
US20110142830A1 (en) 2011-06-16
ES2464459T3 (es) 2014-06-02
EP2732823A1 (en) 2014-05-21

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