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DK2307042T3 - Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte - Google Patents

Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte

Info

Publication number
DK2307042T3
DK2307042T3 DK09768854.3T DK09768854T DK2307042T3 DK 2307042 T3 DK2307042 T3 DK 2307042T3 DK 09768854 T DK09768854 T DK 09768854T DK 2307042 T3 DK2307042 T3 DK 2307042T3
Authority
DK
Denmark
Prior art keywords
trpv
pain
module
treatment
receptor system
Prior art date
Application number
DK09768854.3T
Other languages
English (en)
Inventor
R Anders Nykj
V Gter Christian Bjerggaard
Ole J Bjerrum
Pernille Jansen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK2307042T3 publication Critical patent/DK2307042T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK09768854.3T 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte DK2307042T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7562708P 2008-06-25 2008-06-25
DKPA200800880 2008-06-25
PCT/DK2009/050143 WO2009155932A2 (en) 2008-06-25 2009-06-24 Modulation of the trpv : vps10p-domain receptor system for the treatment of pain

Publications (1)

Publication Number Publication Date
DK2307042T3 true DK2307042T3 (da) 2014-05-12

Family

ID=41445008

Family Applications (2)

Application Number Title Priority Date Filing Date
DK09768854.3T DK2307042T3 (da) 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte
DK14154831.3T DK2732823T3 (da) 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK14154831.3T DK2732823T3 (da) 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte

Country Status (5)

Country Link
US (1) US8460657B2 (da)
EP (2) EP2732823B1 (da)
DK (2) DK2307042T3 (da)
ES (1) ES2464459T3 (da)
WO (1) WO2009155932A2 (da)

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EP3225251B1 (en) 2006-12-21 2020-02-12 H. Lundbeck A/S Modulation of activity of proneurotrophins
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JP2013532144A (ja) * 2010-06-14 2013-08-15 ハー・ルンドベック・アクチエゼルスカベット ＳｏｒＬＡとＧＤＮＦファミリーリガンド受容体の間の相互作用の調節
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WO2014114779A1 (en) 2013-01-28 2014-07-31 H. Lundbeck A/S N-substituted-5-substituted phthalamic acids as sortilin inhibitors
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AU2015209763B2 (en) * 2014-01-23 2020-12-24 Biogaia Ab Selection of agents modulating gastrointestinal pain
JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用
US10849992B1 (en) 2015-04-07 2020-12-01 Alector Llc Methods of screening for sortilin binding antagonists
HRP20211980T1 (hr) 2015-04-07 2022-04-01 Alector Llc Protutijela protiv sortilina i postupci njihove upotrebe
US20190345216A1 (en) * 2015-12-18 2019-11-14 Aarhus Universitet SorCS PEPTIDES AND USES THEREOF
CR20210057A (es) 2018-07-13 2021-03-22 Alector Llc Anticuerpos anti-sortilina y métodos para su uso
WO2021243007A2 (en) * 2020-05-28 2021-12-02 Phor-Med, Inc. Compositions and methods for treating acute respiratory distress syndrome (ards) and inflammatory disorders caused by coronaviruses and other respiratory pathogens or agents that mediate pulmonary injury, inflammation or acute respiratory distress, and related compositions and methods for treating and preventing human sars coronavirus infection, covid-19 disease and related symptoms
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Also Published As

Publication number Publication date
EP2732823B1 (en) 2019-08-07
US8460657B2 (en) 2013-06-11
EP2732823A1 (en) 2014-05-21
ES2464459T3 (es) 2014-06-02
WO2009155932A2 (en) 2009-12-30
US20110142830A1 (en) 2011-06-16
EP2307042B1 (en) 2014-03-26
WO2009155932A3 (en) 2010-04-22
EP2307042A2 (en) 2011-04-13
DK2732823T3 (da) 2019-09-16

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