DK2180787T3 - Nitrooliesyremodulering af type ii-diabetes - Google Patents
Nitrooliesyremodulering af type ii-diabetesInfo
- Publication number
- DK2180787T3 DK2180787T3 DK08780348.2T DK08780348T DK2180787T3 DK 2180787 T3 DK2180787 T3 DK 2180787T3 DK 08780348 T DK08780348 T DK 08780348T DK 2180787 T3 DK2180787 T3 DK 2180787T3
- Authority
- DK
- Denmark
- Prior art keywords
- nitroolic
- diabetes
- type
- acid modulation
- modulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95336007P | 2007-08-01 | 2007-08-01 | |
PCT/US2008/009274 WO2009017802A1 (en) | 2007-08-01 | 2008-08-01 | Nitro-fattyacid modulation of type ii diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2180787T3 true DK2180787T3 (da) | 2014-02-03 |
Family
ID=40304683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08780348.2T DK2180787T3 (da) | 2007-08-01 | 2008-08-01 | Nitrooliesyremodulering af type ii-diabetes |
Country Status (4)
Country | Link |
---|---|
US (8) | US8324277B2 (da) |
EP (2) | EP2679224A1 (da) |
DK (1) | DK2180787T3 (da) |
WO (1) | WO2009017802A1 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3410371B2 (ja) * | 1998-08-18 | 2003-05-26 | リンテック株式会社 | ウエハ裏面研削時の表面保護シートおよびその利用方法 |
WO2005110396A2 (en) | 2004-04-28 | 2005-11-24 | Uab Research Foundation | Nitrated lipids and methods of making and using thereof |
WO2009017802A1 (en) * | 2007-08-01 | 2009-02-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Nitro-fattyacid modulation of type ii diabetes |
WO2009134383A2 (en) * | 2008-05-01 | 2009-11-05 | Complexa Inc. | Vinyl substituted fatty acids |
US8686038B2 (en) | 2008-06-19 | 2014-04-01 | The Univsersity of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
US20140024713A1 (en) | 2008-06-19 | 2014-01-23 | University Of Utah Research Foundation | Use of nitrated lipids for treatment of side effects of toxic medical therapies |
CN102307464A (zh) * | 2008-12-31 | 2012-01-04 | 尼特罗米加公司 | 含有硝基脂肪酸的营养制品 |
WO2011014261A1 (en) | 2009-07-31 | 2011-02-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Fatty acids as anti-inflammatory agents |
US8686167B2 (en) | 2009-10-02 | 2014-04-01 | Complexa, Inc. | Heteroatom containing substituted fatty acids |
WO2011089265A1 (en) | 2010-01-25 | 2011-07-28 | Bridge Bioresearch Plc | Use of fatty acid compounds for lowering blood glucose levels |
JP2013526865A (ja) | 2010-05-13 | 2013-06-27 | ニトロメガ コーポレーション | ニトロ脂肪酸、神経保護および/または認識減退の抑制 |
JP2013534930A (ja) * | 2010-06-28 | 2013-09-09 | コンプレクサ,インコーポレイテッド | 糖尿病を治療するための多成分調剤 |
WO2013028501A1 (en) | 2011-08-19 | 2013-02-28 | The University Of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
EP3303339B1 (en) | 2015-07-07 | 2021-01-13 | H. Lundbeck A/S | Pde9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases |
CN113440506A (zh) | 2015-10-02 | 2021-09-28 | 康普莱克夏公司 | 使用治疗有效量的活化脂肪酸预防、治疗和逆转疾病 |
CN109071405A (zh) | 2016-03-04 | 2018-12-21 | 高等教育联邦系统-匹兹堡大学 | 使用治疗有效量的二羧酸化合物预防、治疗和逆转疾病 |
JP2019529501A (ja) | 2016-10-05 | 2019-10-17 | ユニバーシティ オブ ピッツバーグ−オブ ザ コモンウェルス システム オブ ハイヤー エデュケーションUniversity Of Pittsburgh Of The Commonwealth System Of Higher Education | 可逆的に保護された、チオレート化求電子性脂肪酸としてのプロドラッグ |
JP2019529517A (ja) * | 2016-10-05 | 2019-10-17 | ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | ニトロソ化およびアルキル化反応を媒介するニトロアルケンの新規可逆的窒素酸化物誘導体 |
KR20210014662A (ko) | 2018-05-25 | 2021-02-09 | 이마라 인크. | 6-[(3S,4S)-4-메틸-1-(피리미딘-2-일메틸)피롤리딘-3-일]-3-테트라히드로피란-4-일-7H-이미다조[1,5-a]피라진-8-온의 일수화물 및 결정형 |
EP3843737A4 (en) | 2018-08-31 | 2022-06-01 | Imara Inc. | PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE |
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WO2013028501A1 (en) | 2011-08-19 | 2013-02-28 | The University Of Utah Research Foundation | Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system |
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-
2008
- 2008-08-01 WO PCT/US2008/009274 patent/WO2009017802A1/en active Application Filing
- 2008-08-01 EP EP13179211.1A patent/EP2679224A1/en not_active Withdrawn
- 2008-08-01 US US12/670,951 patent/US8324277B2/en active Active
- 2008-08-01 DK DK08780348.2T patent/DK2180787T3/da active
- 2008-08-01 EP EP08780348.2A patent/EP2180787B1/en active Active
-
2012
- 2012-11-01 US US13/666,827 patent/US8735449B2/en active Active
-
2014
- 2014-04-03 US US14/244,741 patent/US9186408B2/en not_active Expired - Fee Related
-
2015
- 2015-10-26 US US14/923,265 patent/US9700534B2/en active Active
-
2017
- 2017-06-21 US US15/629,277 patent/US10258589B2/en active Active
-
2019
- 2019-02-20 US US16/280,704 patent/US10576051B2/en active Active
-
2020
- 2020-01-21 US US16/748,453 patent/US10869850B2/en active Active
- 2020-11-17 US US16/950,805 patent/US20210220315A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20130059912A1 (en) | 2013-03-07 |
EP2180787A4 (en) | 2010-09-01 |
US20210220315A1 (en) | 2021-07-22 |
US20140309303A1 (en) | 2014-10-16 |
US20160045467A1 (en) | 2016-02-18 |
US9700534B2 (en) | 2017-07-11 |
US20180250257A9 (en) | 2018-09-06 |
US20190274987A1 (en) | 2019-09-12 |
US20100216884A1 (en) | 2010-08-26 |
EP2180787B1 (en) | 2013-10-30 |
US9186408B2 (en) | 2015-11-17 |
US10869850B2 (en) | 2020-12-22 |
WO2009017802A1 (en) | 2009-02-05 |
WO2009017802A9 (en) | 2014-12-04 |
US10258589B2 (en) | 2019-04-16 |
EP2679224A1 (en) | 2014-01-01 |
US8324277B2 (en) | 2012-12-04 |
US10576051B2 (en) | 2020-03-03 |
US8735449B2 (en) | 2014-05-27 |
US20180125806A1 (en) | 2018-05-10 |
US20200230095A1 (en) | 2020-07-23 |
EP2180787A1 (en) | 2010-05-05 |
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