DK1844074T3 - Humane antistoffer og proteiner - Google Patents
Humane antistoffer og proteinerInfo
- Publication number
- DK1844074T3 DK1844074T3 DK06709606.5T DK06709606T DK1844074T3 DK 1844074 T3 DK1844074 T3 DK 1844074T3 DK 06709606 T DK06709606 T DK 06709606T DK 1844074 T3 DK1844074 T3 DK 1844074T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteins
- human antibodies
- antibodies
- human
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0502201A GB0502201D0 (en) | 2005-02-03 | 2005-02-03 | Human antibodies |
| GB0503190A GB0503190D0 (en) | 2005-02-16 | 2005-02-16 | Human antibodies |
| GB0506945A GB0506945D0 (en) | 2005-04-05 | 2005-04-05 | Human antibodies |
| PCT/GB2006/000355 WO2006082406A2 (en) | 2005-02-03 | 2006-02-03 | Human antibodies and proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1844074T3 true DK1844074T3 (da) | 2013-07-15 |
Family
ID=36777595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06709606.5T DK1844074T3 (da) | 2005-02-03 | 2006-02-03 | Humane antistoffer og proteiner |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20080206239A1 (da) |
| EP (2) | EP1844074B1 (da) |
| JP (4) | JP2008528668A (da) |
| KR (1) | KR101385886B1 (da) |
| CN (1) | CN101115771B (da) |
| AU (1) | AU2006210724A1 (da) |
| CA (1) | CA2596833C (da) |
| DK (1) | DK1844074T3 (da) |
| ES (1) | ES2417133T3 (da) |
| WO (1) | WO2006082406A2 (da) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040067532A1 (en) | 2002-08-12 | 2004-04-08 | Genetastix Corporation | High throughput generation and affinity maturation of humanized antibody |
| CA2560278C (en) | 2004-03-19 | 2012-11-20 | Matthew Baker | Modified bouganin proteins, cytotoxins and methods and uses thereof |
| DK1844074T3 (da) * | 2005-02-03 | 2013-07-15 | Antitope Ltd | Humane antistoffer og proteiner |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| EP2438962A3 (en) | 2006-02-13 | 2012-07-18 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in the process of bone remodeling |
| EP2080138A2 (en) * | 2006-10-11 | 2009-07-22 | Antitope Limited | T cell epitope databases |
| EP2450372B1 (en) | 2007-01-30 | 2015-04-22 | Epivax, Inc. | Regulatory T cell epitopes, compositions and uses thereof |
| AU2016203577B2 (en) * | 2007-01-30 | 2017-12-21 | Epivax, Inc. | Regulatory T cell epitopes, compositions and uses thereof |
| JP5749009B2 (ja) | 2007-08-13 | 2015-07-15 | バスジーン セラピューティクス, インコーポレイテッドVasgenetherapeutics, Inc. | EphB4に結合するヒト化抗体を利用する癌治療剤 |
| US12529164B2 (en) | 2007-09-14 | 2026-01-20 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| CA3187687A1 (en) | 2007-09-14 | 2009-03-19 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| MX2010006148A (es) | 2007-12-06 | 2011-02-23 | Dana Farber Cancer Inst Inc | Anti-cuerpos contra el virus de la influenza y metodos de uso de los mismos. |
| CN102264762B (zh) * | 2008-09-26 | 2018-03-27 | 达纳-法伯癌症研究公司 | 人抗pd‑1、pd‑l1和pd‑l2的抗体及其应用 |
| AU2010231516A1 (en) | 2009-03-30 | 2011-10-27 | Protab Ltd. | Adenylyl Cyclase-Associated Protein (CAP1) and uses thereof as a target for immuno-modulation |
| TWI559930B (en) * | 2009-04-16 | 2016-12-01 | Abbvie Biotherapeutics Inc | Anti-tnf-α antibodies and their uses |
| IE20090514A1 (en) | 2009-07-06 | 2011-02-16 | Opsona Therapeutics Ltd | Humanised antibodies and uses therof |
| RU2595409C2 (ru) | 2009-09-03 | 2016-08-27 | Мерк Шарп И Доум Корп., | Анти-gitr-антитела |
| EP2475383A4 (en) | 2009-09-06 | 2013-07-17 | Protab Ltd | FOR THE PEPTIDE PRODUCED FROM HSP65 6 SPECIFIC HUMANIZED ANTIBODIES AND USES THEREOF |
| RU2673908C2 (ru) | 2009-12-02 | 2018-12-03 | Имэджинэб, Инк. | Мини-антитела j591 и цис-диатела для направленной доставки простата-специфичного мембранного антигена (psma) человека и способы их применения |
| WO2011149461A1 (en) | 2010-05-27 | 2011-12-01 | Medtronic, Inc. | Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules |
| NZ604510A (en) | 2010-08-17 | 2013-10-25 | Csl Ltd | Dilutable biocidal compositions and methods of use |
| GB201103955D0 (en) | 2011-03-09 | 2011-04-20 | Antitope Ltd | Antibodies |
| GB201109238D0 (en) | 2011-06-01 | 2011-07-13 | Antitope Ltd | Antibodies |
| FR2984750B1 (fr) | 2011-12-23 | 2014-01-10 | Lfb Biotechnologies | Nouvelles compositions pharmaceutiques comprenant un anticorps liant le recepteur humain de l'hormone anti-mullerienne de type ii |
| US10000567B2 (en) | 2012-06-14 | 2018-06-19 | Therapix Biosciences Ltd. | Humanized antibodies to cluster of differentiation 3 (CD3) |
| KR20150036274A (ko) | 2012-07-19 | 2015-04-07 | 알레시아 바이오쎄라퓨틱스 인코포레이티드 | 항-siglec-15 항체 |
| EP3539563A1 (en) | 2012-07-19 | 2019-09-18 | Redwood Bioscience, Inc. | Antibody specific for cd22 and methods of use thereof |
| WO2014041544A1 (en) * | 2012-09-12 | 2014-03-20 | Ramot At Tel-Aviv University Ltd. | Immunoparticles and methods of generating and using same |
| RS57694B1 (sr) | 2012-10-12 | 2018-11-30 | Adc Therapeutics Sa | Pirolobenzodiazepin - anti-psma konjugati antitela |
| PL2906251T3 (pl) | 2012-10-12 | 2018-02-28 | Adc Therapeutics Sa | Koniugaty pirolobenzodiazepina-przeciwciało anty-CD22 |
| SMT201800346T1 (it) | 2012-10-12 | 2018-09-13 | Medimmune Ltd | Coniugati pirrolobenzodiazepina-anticorpo |
| SMT202100265T1 (it) | 2012-10-12 | 2021-07-12 | Medimmune Ltd | Pirrolobenzodiazepine e loro coniugati |
| KR101995619B1 (ko) | 2012-10-12 | 2019-07-03 | 에이디씨 테라퓨틱스 에스에이 | 피롤로벤조디아제핀-항체 컨주게이트 |
| WO2014057120A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-antibody conjugates |
| WO2014057114A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-anti-psma antibody conjugates |
| EP2839860B1 (en) | 2012-10-12 | 2019-05-01 | MedImmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| RU2681994C2 (ru) * | 2012-12-26 | 2019-03-14 | Онкосинерджи, Инк. | КОМПОЗИЦИИ АНТИТЕЛА К ИНТЕГРИНУ β1 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| WO2014140174A1 (en) | 2013-03-13 | 2014-09-18 | Spirogen Sàrl | Pyrrolobenzodiazepines and conjugates thereof |
| JP6546162B2 (ja) * | 2013-07-05 | 2019-07-17 | ゲンマブ エー/エス | ヒト化またはキメラcd3抗体 |
| EP3054986B1 (en) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| EP3054983B1 (en) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| US9950078B2 (en) | 2013-10-11 | 2018-04-24 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| EP3193940A1 (en) | 2014-09-10 | 2017-07-26 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| CN107148285B (zh) | 2014-11-25 | 2022-01-04 | Adc治疗股份有限公司 | 吡咯并苯并二氮杂䓬-抗体缀合物 |
| CA2970255A1 (en) * | 2014-12-17 | 2016-06-23 | Intrexon Corporation | Intercalated single-chain variable fragments |
| CA3226056A1 (en) * | 2015-01-21 | 2016-07-28 | Inhibrx, Inc. | Non-immunogenic single domain antibodies |
| MX386896B (es) | 2015-04-10 | 2025-03-19 | Univ Jefferson | Composiciones y el uso de las mismas para incrementar la inmunidad terapéutica reduciendo selectivamente los monocitos m2 inmunomoduladores. |
| GB201506389D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| JP7026613B2 (ja) | 2015-08-07 | 2022-02-28 | イマジナブ・インコーポレーテッド | 標的分子に対する抗原結合コンストラクト |
| US12102689B2 (en) | 2015-11-09 | 2024-10-01 | R.P. Scherer Technologies, Llc | Anti-CD22 antibody-maytansine conjugates and methods of use thereof |
| GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
| GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| LT3445785T (lt) | 2016-04-18 | 2022-10-10 | Faron Pharmaceuticals Oy | Humanizuoti anti clever-1 antikūnai ir jų naudojimas |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| ES3034904T3 (en) | 2016-07-18 | 2025-08-27 | Univ Ramot | Modular platform for targeted therapeutics |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
| JP6671555B2 (ja) | 2017-02-08 | 2020-03-25 | アーデーセー セラピューティクス ソシエテ アノニム | ピロロベンゾジアゼピン抗体複合体 |
| NZ754811A (en) | 2017-02-08 | 2023-06-30 | Medimmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| CN110582505B (zh) | 2017-04-18 | 2021-04-02 | 免疫医疗有限公司 | 吡咯并苯并二氮杂*缀合物 |
| MX2019012464A (es) | 2017-04-20 | 2019-12-11 | Adc Therapeutics Sa | Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl. |
| AU2018285562B2 (en) | 2017-06-14 | 2024-01-18 | Adc Therapeutics Sa | Dosage regimes for the administration of an anti-CD19 ADC |
| ES2906965T3 (es) | 2017-08-18 | 2022-04-21 | Medimmune Ltd | Conjugados de pirrolobenzodiazepina |
| WO2019136300A2 (en) * | 2018-01-05 | 2019-07-11 | Immunext, Inc. | Anti-mct1 antibodies and uses thereof |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| ES2967878T3 (es) | 2019-03-15 | 2024-05-06 | Medimmune Ltd | Dímeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento del cáncer |
| WO2020237092A2 (en) * | 2019-05-21 | 2020-11-26 | The Regents Of The University Of California | Mmp-9 antibodies and methods of use thereof |
| US11332546B2 (en) | 2019-05-21 | 2022-05-17 | The Regents Of The University Of California | Protease inhibitory antibodies and methods of use thereof |
| GB201908128D0 (en) | 2019-06-07 | 2019-07-24 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
| TW202208427A (zh) * | 2020-05-06 | 2022-03-01 | 德商因夫萊亞斯有限公司 | 人源化抗c5a抗體 |
| GB202011993D0 (en) | 2020-07-31 | 2020-09-16 | Adc Therapeutics Sa | ANTI-IL 13Ra2 antibodies |
| GB202015226D0 (en) | 2020-09-25 | 2020-11-11 | Adc Therapeutics S A | Pyrrol obenzodiazepine-antibody conugates and uses thereof |
| AU2023336804A1 (en) | 2022-09-09 | 2025-01-16 | Imperial College Innovations Limited | Cytotoxic imidazo[1,2-a]pyridine compounds and their use in therapy |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
| GB202403391D0 (en) | 2024-03-08 | 2024-04-24 | Myricx Pharma Ltd | Novel compounds and their use in therapy |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994510A (en) * | 1990-12-21 | 1999-11-30 | Celltech Therapeutics Limited | Recombinant antibodies specific for TNFα |
| US5656272A (en) | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| US6277969B1 (en) | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
| DE69233254T2 (de) | 1991-06-14 | 2004-09-16 | Genentech, Inc., South San Francisco | Humanisierter Heregulin Antikörper |
| DE69230545T2 (de) * | 1991-08-21 | 2000-07-06 | Novartis Ag, Basel | Antikörperderivate |
| US6310185B1 (en) | 1994-03-08 | 2001-10-30 | Memorial Sloan Kettering Cancer Center | Recombinant human anti-Lewis Y antibodies |
| CU22615A1 (es) * | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos |
| JP2002512624A (ja) * | 1997-05-21 | 2002-04-23 | バイオベーション リミテッド | 非免疫原性タンパク質の製造方法 |
| CA2302147C (en) | 1997-09-03 | 2008-05-13 | Biovation Limited | Methods for protein screening |
| US6835550B1 (en) * | 1998-04-15 | 2004-12-28 | Genencor International, Inc. | Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins |
| ATE352559T1 (de) * | 1998-12-08 | 2007-02-15 | Biovation Ltd | Verfahren zur verminderung der immunogenität von proteinen |
| EP1998266A3 (en) * | 2001-02-19 | 2009-02-11 | Merck Patent GmbH | Method for identification of T-cell epitopes and use for preparing molecules with reduced immunogenicity |
| ES2346517T3 (es) | 2001-11-12 | 2010-10-18 | Merck Patent Gmbh | Anticuerpo modificado anti-tnf alfa. |
| US7425533B2 (en) | 2003-06-26 | 2008-09-16 | Merck Patent Gmbh | Modified hirudin proteins and T-cell epitopes in hirudin |
| CA2560278C (en) | 2004-03-19 | 2012-11-20 | Matthew Baker | Modified bouganin proteins, cytotoxins and methods and uses thereof |
| DK1844074T3 (da) * | 2005-02-03 | 2013-07-15 | Antitope Ltd | Humane antistoffer og proteiner |
| WO2006124866A2 (en) * | 2005-05-13 | 2006-11-23 | The Johns Hopkins University | Free human serum ige immunoenzymetric assay and methods of use |
| JP5538278B2 (ja) * | 2011-03-22 | 2014-07-02 | 株式会社ジャパンディスプレイ | 液晶表示素子の製造方法および液晶表示素子 |
| JP6054630B2 (ja) * | 2012-05-18 | 2016-12-27 | ヤマト包装技術研究所株式会社 | 物品拘束具、ロールボックスパレット及び物品の固定方法 |
-
2006
- 2006-02-03 DK DK06709606.5T patent/DK1844074T3/da active
- 2006-02-03 KR KR1020077019951A patent/KR101385886B1/ko not_active Expired - Fee Related
- 2006-02-03 EP EP06709606.5A patent/EP1844074B1/en not_active Expired - Lifetime
- 2006-02-03 US US11/815,507 patent/US20080206239A1/en not_active Abandoned
- 2006-02-03 JP JP2007553693A patent/JP2008528668A/ja active Pending
- 2006-02-03 CN CN2006800040680A patent/CN101115771B/zh not_active Expired - Lifetime
- 2006-02-03 AU AU2006210724A patent/AU2006210724A1/en not_active Abandoned
- 2006-02-03 WO PCT/GB2006/000355 patent/WO2006082406A2/en not_active Ceased
- 2006-02-03 ES ES06709606T patent/ES2417133T3/es not_active Expired - Lifetime
- 2006-02-03 EP EP11177723A patent/EP2388271A3/en not_active Withdrawn
- 2006-02-03 CA CA2596833A patent/CA2596833C/en not_active Expired - Fee Related
-
2012
- 2012-09-10 JP JP2012198433A patent/JP5461643B2/ja not_active Expired - Lifetime
-
2013
- 2013-11-21 JP JP2013241187A patent/JP2014073128A/ja active Pending
-
2014
- 2014-07-07 US US14/324,520 patent/US20150031860A1/en not_active Abandoned
- 2014-07-07 US US14/324,478 patent/US20150031550A1/en not_active Abandoned
-
2016
- 2016-06-02 JP JP2016111176A patent/JP2016210782A/ja active Pending
-
2017
- 2017-03-28 US US15/471,290 patent/US20170210820A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HK1109636A1 (en) | 2008-06-13 |
| JP2014073128A (ja) | 2014-04-24 |
| EP2388271A3 (en) | 2012-08-01 |
| EP1844074A2 (en) | 2007-10-17 |
| EP2388271A2 (en) | 2011-11-23 |
| KR20070107739A (ko) | 2007-11-07 |
| CA2596833C (en) | 2016-04-12 |
| US20170210820A1 (en) | 2017-07-27 |
| AU2006210724A1 (en) | 2006-08-10 |
| CN101115771A (zh) | 2008-01-30 |
| WO2006082406A2 (en) | 2006-08-10 |
| CA2596833A1 (en) | 2006-08-10 |
| JP2013028616A (ja) | 2013-02-07 |
| JP5461643B2 (ja) | 2014-04-02 |
| US20150031550A1 (en) | 2015-01-29 |
| KR101385886B1 (ko) | 2014-04-24 |
| ES2417133T3 (es) | 2013-08-06 |
| WO2006082406A3 (en) | 2007-02-01 |
| EP1844074B1 (en) | 2013-04-24 |
| US20150031860A1 (en) | 2015-01-29 |
| JP2016210782A (ja) | 2016-12-15 |
| JP2008528668A (ja) | 2008-07-31 |
| US20080206239A1 (en) | 2008-08-28 |
| CN101115771B (zh) | 2013-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1844074T3 (da) | Humane antistoffer og proteiner | |
| NO20080692L (no) | SP35 antistoffer og anvendelse derav | |
| DK1957539T3 (da) | Humane monoklonale antistoffer til proteintyrosinkinase 7 (ptk7) og deres anvendelse | |
| DK1971366T3 (da) | Humane anti-IL-23-antistoffer, sammensætninger, fremgangsmåder og anvendelser | |
| ATE484525T1 (de) | Modifizierte humane igf-1r antikörper | |
| PT1920065T (pt) | Anticorpos anti-alfavbeta6 e suas utilizações | |
| DK1868642T3 (da) | Katte-allergenfusionsproteiner og anvendelser deraf | |
| KR101413615B9 (ko) | 인간 프로토피브릴에 선택적인 개선된 항체 및 이의 용도 | |
| HRP20220755T3 (hr) | Anti-gm-csf antitijela i njihova uporaba | |
| DK1877090T3 (da) | Trimert ox40-immunoglobulin-fusionsprotein og fremgangsmåder til anvendelse heraf | |
| HUE044756T2 (hu) | HER-3 elleni antitestek és alkalmazásuk | |
| NO20082454L (no) | Anti-alfa2 integrin antistoffer og deres anvendelser | |
| IL191759A (en) | Ganaxolone formulations and methods for the making and use thereof | |
| CU23869B1 (es) | Anticuerpos anti-esclerostina y proteínas funcionales | |
| DK1960434T3 (da) | Monoklonale, humane antistoffer mod Fucosyl-GM1 og fremgangsmåder til anvendelse af anti-Fucosyl-GM1 | |
| DK1934179T3 (da) | Fremgangsmåder og mellemprodukter | |
| ATE480567T1 (de) | Hochkonzentrierter antikörper und proteinformulierungen | |
| EP1895838A4 (en) | COMPOSITIONS AND METHODS | |
| DK2118140T3 (da) | Humancytomegalovirus-neutraliserende antistoffer og anvendelse deraf | |
| DK1711207T3 (da) | Interferon-alpha-antistoffer og anvendelse heraf | |
| DK1737961T3 (da) | Modificerede bouganin proteiner, cytotoxiner og fremgangsmåder og anvendelser deraf | |
| DK1817343T3 (da) | Humane monoklone antistoffer mod humant IL-4 | |
| DK1885716T3 (da) | Thiazolderivater og anvendelse deraf | |
| DK1809660T3 (da) | Thymus-specifikt protein | |
| DK1840121T3 (da) | Glycinderivat og anvendelse heraf |