DK1719775T3 - Camptotheciner med en modificeret lactonring - Google Patents

Camptotheciner med en modificeret lactonring

Info

Publication number: DK1719775T3
Authority: DK; Denmark
Prior art keywords: camptothecins; lactone ring; modified lactone; modified; ring
Prior art date: 2002-05-31

Application number

DK06116366T

Other languages

Danish (da)

English (en)

Inventor

Mauro Marzi

Elena Marastoni

Sergio Penco

Claudio Pisano

Maria Ornella Tinti

Loredana Vesci

Franco Zunino

Domenico Vergani

Walter Cabri

Marco Alpegiani

Martin Patricio

Tamara Danelli

Original Assignee

Sigma Tau Ind Farmaceuti

Ist Naz Stud Cura Dei Tumori

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-31

Filing date

2003-05-28

Publication date

2008-11-17

2003-05-28 Application filed by Sigma Tau Ind Farmaceuti, Ist Naz Stud Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti

2008-11-17 Application granted granted Critical

2008-11-17 Publication of DK1719775T3 publication Critical patent/DK1719775T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)

DK06116366T 2002-05-31 2003-05-28 Camptotheciner med en modificeret lactonring DK1719775T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2002RM000305A ITRM20020305A1 (it)	2002-05-31	2002-05-31	Camptotecine con anello lattonico modificato.
PCT/IT2003/000328 WO2003101995A2 (en)	2002-05-31	2003-05-28	Camptothecins with a modified lactone ring

Publications (1)

Publication Number	Publication Date
DK1719775T3 true DK1719775T3 (da)	2008-11-17

Family

ID=11456338

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK06116366T DK1719775T3 (da)	2002-05-31	2003-05-28	Camptotheciner med en modificeret lactonring
DK03730480.5T DK1511752T5 (da)	2002-05-31	2003-05-28	Camptotheciner med modificeret lactonring

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK03730480.5T DK1511752T5 (da)	2002-05-31	2003-05-28	Camptotheciner med modificeret lactonring

Country Status (22)

Country	Link
US (1)	US7273873B2 (sl)
EP (2)	EP1511752B3 (sl)
JP (1)	JP4693410B2 (sl)
KR (1)	KR101042042B1 (sl)
CN (1)	CN1656100A (sl)
AR (1)	AR040139A1 (sl)
AT (2)	ATE403659T1 (sl)
AU (2)	AU2003241160B2 (sl)
BR (2)	BR0311333A (sl)
CA (2)	CA2485201C (sl)
CY (2)	CY1107311T1 (sl)
DE (2)	DE60308368T3 (sl)
DK (2)	DK1719775T3 (sl)
ES (2)	ES2312090T3 (sl)
IT (1)	ITRM20020305A1 (sl)
MX (1)	MXPA04011682A (sl)
PE (1)	PE20050120A1 (sl)
PL (1)	PL374346A1 (sl)
PT (2)	PT1511752E (sl)
SI (2)	SI1719775T1 (sl)
TW (1)	TWI325866B (sl)
WO (1)	WO2003101995A2 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2852606A1 (fr) *	2003-03-18	2004-09-24	Inst Nat Sante Rech Med	Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
ITRM20030344A1 (it)	2003-07-14	2005-01-15	Ist Naz Stud Cura Dei Tumori	7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
EP2170900B1 (en)	2007-08-01	2012-12-12	SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.	Crystalline form ii of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom
CN102746314B (zh) *	2011-04-18	2016-07-06	华东师范大学	含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN104530066A (zh) *	2015-01-06	2015-04-22	华东师范大学	一类新型高喜树碱衍生物、制备方法和用途
BR112021022008A2 (pt)	2019-05-14	2022-05-17	Nuvation Bio Inc	Compostos de direcionamento a receptor de hormônio nuclear anticâncer
WO2021097046A1 (en)	2019-11-13	2021-05-20	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds
IL306010A (en)	2021-03-23	2023-11-01	Nuvation Bio Inc	Anticancer compounds against the nuclear hormone receptor
US12006314B2 (en)	2021-05-03	2024-06-11	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds
WO2024073626A2 (en) *	2022-09-28	2024-04-04	Nuvation Bio Inc.	Anti-cancer nuclear hormone receptor-targeting compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4399276A (en) *	1981-01-09	1983-08-16	Kabushiki Kaisha Yakult Honsha	7-Substituted camptothecin derivatives
JPS57116076A (en) *	1981-01-09	1982-07-19	Yakult Honsha Co Ltd	Novel camptothecin derivative and its preparation
FR2532591A1 (fr)	1982-09-02	1984-03-09	Hutchinson	Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins
DK1251125T3 (da) *	1995-06-21	2006-04-18	Sod Conseils Rech Applic	Hidtil ukendte camptothecin-analoger, fremgangsmåde til fremstilling heraf, anvendelse heraf som lægemidler og farmaceutiske præparater indeholdende disse
SI1044977T1 (sl) *	1999-03-09	2002-08-31	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Derivati kamptotecina, ki imajo protitumorno delovanje

2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 EP EP03730480A patent/EP1511752B3/en not_active Expired - Lifetime
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 EP EP06116366A patent/EP1719775B1/en not_active Expired - Lifetime
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en active IP Right Grant
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active IP Right Cessation
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased

Also Published As

Publication number	Publication date
WO2003101995A2 (en)	2003-12-11
AU2003241160B2 (en)	2009-08-20
JP4693410B2 (ja)	2011-06-01
ES2312090T3 (es)	2009-02-16
CY1108793T1 (el)	2014-04-09
ITRM20020305A1 (it)	2003-12-01
MXPA04011682A (es)	2005-03-31
JP2005531602A (ja)	2005-10-20
EP1511752B8 (en)	2007-04-18
CN1656100A (zh)	2005-08-17
AU2003241160A1 (en)	2003-12-19
SI1511752T1 (sl)	2007-02-28
BR0311333A (pt)	2005-03-15
TWI325866B (en)	2010-06-11
EP1511752B3 (en)	2010-03-10
EP1719775B1 (en)	2008-08-06
CY1107311T1 (el)	2012-11-21
CA2485201A1 (en)	2003-12-11
ATE403659T1 (de)	2008-08-15
AU2009236044B2 (en)	2011-03-24
ATE339422T1 (de)	2006-10-15
US7273873B2 (en)	2007-09-25
DK1511752T3 (da)	2007-01-29
PT1719775E (pt)	2008-09-30
AR040139A1 (es)	2005-03-16
ES2273002T7 (es)	2011-08-01
DE60308368T2 (de)	2007-09-06
DE60322754D1 (de)	2008-09-18
DE60308368T3 (de)	2010-09-16
DE60308368D1 (de)	2006-10-26
AU2009236044A1 (en)	2009-12-03
EP1511752A2 (en)	2005-03-09
EP1719775A1 (en)	2006-11-08
US20050154003A1 (en)	2005-07-14
DK1511752T5 (da)	2010-06-14
TW200404806A (en)	2004-04-01
AU2009236044B8 (en)	2011-07-21
BR0311329A (pt)	2005-02-22
ES2273002T3 (es)	2007-05-01
PT1511752E (pt)	2007-01-31
WO2003101995A3 (en)	2004-02-19
PE20050120A1 (es)	2005-03-04
CA2485201C (en)	2010-11-02
KR101042042B1 (ko)	2011-06-16
PL374346A1 (en)	2005-10-17
SI1719775T1 (sl)	2009-04-30
ITRM20020305A0 (it)	2002-05-31
WO2003101995A8 (en)	2004-12-23
AU2009236044A8 (en)	2011-07-21
KR20050036909A (ko)	2005-04-20
EP1511752B1 (en)	2006-09-13
CA2706635A1 (en)	2003-12-11

Publication	Publication Date	Title
DE60330079D1 (de)	2009-12-24	Ölring
DE03726967T1 (de)	2005-05-04	Wirbelringerzeuger
NO20054339D0 (no)	2005-09-20	Forede bronnboringer med maksimal diameter
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EP1717230A4 (en)	2009-09-23	4-OXOPYRIMIDINE DERIVED FUSIONED CYCLES
FR2837895B1 (fr)	2007-02-09	Segment de piston
DE60332581D1 (de)	2010-07-01	Induktiver Stellungsgeber
ATE453811T1 (de)	2010-01-15	Synchronring
DK1719775T3 (da)	2008-11-17	Camptotheciner med en modificeret lactonring
FR2842459B1 (fr)	2006-06-16	Reliure a anneaux
DE60239391D1 (de)	2011-04-21	rgungsringes mit großem parasitärem Widerstand
DE112005001543T5 (de)	2007-05-16	Entlüfteter Einspritzventil-Aussenring
FR2847399B1 (fr)	2007-08-24	Recepteur a configuration double
FR2838029B1 (fr)	2005-12-30	Bague
DE60200407D1 (de)	2004-06-03	Methylendioxy- Derivate
DE10393274D2 (de)	2005-05-25	Palettiergerät
FI20020799A0 (fi)	2002-04-26	Voimalaite
FR2848277B1 (fr)	2008-04-25	Segment de piston
ATA16062002A (de)	2003-07-15	Schlüsselanhänger
DE20318238U1 (de)	2005-03-31	Beissring
ES1052520Y (es)	2003-04-16	Dispositivo anillo abre-botellas
ITMI20022357A1 (it)	2004-05-07	Palettizzatore