DK1483369T3 - Fuglecellelinier til fremstiling af stoffer af interesse - Google Patents
Fuglecellelinier til fremstiling af stoffer af interesseInfo
- Publication number
- DK1483369T3 DK1483369T3 DK03725273T DK03725273T DK1483369T3 DK 1483369 T3 DK1483369 T3 DK 1483369T3 DK 03725273 T DK03725273 T DK 03725273T DK 03725273 T DK03725273 T DK 03725273T DK 1483369 T3 DK1483369 T3 DK 1483369T3
- Authority
- DK
- Denmark
- Prior art keywords
- cell lines
- serum
- growth factors
- medium
- feeder layer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
- Farming Of Fish And Shellfish (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0202945A FR2836924B1 (fr) | 2002-03-08 | 2002-03-08 | Lignees de cellules aviaires utiles pour la production de substances d'interet |
PCT/FR2003/000735 WO2003076601A1 (fr) | 2002-03-08 | 2003-03-07 | Lignées de cellules aviaires utiles pour la production de substances d'intérêt |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1483369T3 true DK1483369T3 (da) | 2008-12-01 |
Family
ID=27763651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03725273T DK1483369T3 (da) | 2002-03-08 | 2003-03-07 | Fuglecellelinier til fremstiling af stoffer af interesse |
Country Status (14)
Country | Link |
---|---|
US (4) | US20040058441A1 (de) |
EP (2) | EP1483369B1 (de) |
JP (2) | JP5025888B2 (de) |
CN (2) | CN100562567C (de) |
AT (1) | ATE408004T1 (de) |
AU (1) | AU2003227820B2 (de) |
CA (1) | CA2478125C (de) |
DE (1) | DE60323468D1 (de) |
DK (1) | DK1483369T3 (de) |
ES (1) | ES2312775T3 (de) |
FR (1) | FR2836924B1 (de) |
PT (1) | PT1483369E (de) |
SI (1) | SI1483369T1 (de) |
WO (1) | WO2003076601A1 (de) |
Families Citing this family (120)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7445924B2 (en) | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
US7145057B2 (en) | 2002-02-01 | 2006-12-05 | Origen Therapeutics, Inc. | Chimeric bird from embryonic stem cells |
US20060191026A1 (en) | 2005-02-18 | 2006-08-24 | Origen Therapeutics, Inc. | Tissue specific expression of antibodies in chickens |
FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
BRPI0313559B8 (pt) * | 2002-09-05 | 2021-05-25 | Bavarian Nordic As | método para o cultivo de células primárias e para a amplificação de vírus sob condições isentas de soro |
CA2510229A1 (en) * | 2002-12-13 | 2004-07-08 | Aventis Pasteur, Inc. | Production of alvac on avian embryonic stem cells |
EP1500699A1 (de) * | 2003-07-22 | 2005-01-26 | Vivalis | Herstellung von Vacciniaviren mit Hilfe adhärenter oder nicht adhärenter Vogelzelllinien |
EP2143788A1 (de) | 2003-07-22 | 2010-01-13 | Vivalis | Produktion von Pockenviren mit Entenzelllinien |
WO2005028634A2 (en) * | 2003-09-18 | 2005-03-31 | Emory University | Improved mva vaccines |
EP1766034B1 (de) | 2004-05-21 | 2014-03-19 | Novartis Vaccines and Diagnostics, Inc. | Alphavirus-vektoren für impfstoffe gegen das influenza virus |
DK1789084T3 (da) | 2004-09-09 | 2011-01-10 | Novartis Vaccines & Diagnostic | Nedsættelse af potentiellle iatrogene risici forbundet med influenzavacciner |
EP1807116B1 (de) | 2004-11-03 | 2015-05-06 | Novartis Vaccines and Diagnostics, Inc. | Grippeimpfung |
FR2878860A1 (fr) * | 2004-12-08 | 2006-06-09 | Vivalis Sa | Lignees de cellules souches humaines derivees de cellules es et utilisations pour la production de vaccins et de proteines recombinantes |
AU2011253998B2 (en) * | 2005-04-11 | 2014-04-24 | Valneva | Process of manufacturing viral vaccines in suspension avian embryonic derived stem cell lines |
FR2884255B1 (fr) * | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
EA014062B1 (ru) | 2005-11-01 | 2010-08-30 | Новартис Вэксинс Энд Диагностикс Гмбх & Ко Кг | Вирусные вакцины, полученные из клеток с низкими уровнями остаточной клеточной днк |
DE06808434T1 (de) | 2005-11-04 | 2009-12-17 | Novartis Vaccines And Diagnostics S.R.L. | Emulsionen mit freiem wässrigen phasen tensid als adjuvans für spalt-grippeimpfstoffe |
NZ567978A (en) | 2005-11-04 | 2011-09-30 | Novartis Vaccines & Diagnostic | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
PT1951299E (pt) | 2005-11-04 | 2012-02-28 | Novartis Vaccines & Diagnostic | Vacinas contra a gripe que incluem combinações de adjuvantes particulados e imuno-potenciadores |
NZ592713A (en) | 2005-11-04 | 2012-12-21 | Novartis Vaccines & Diagnostic | Adjuvanted influenza vaccines including a cytokine-inducing agents other than an agonist of Toll-Like Receptor 9 |
CA2628152C (en) | 2005-11-04 | 2016-02-02 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
JP6087041B2 (ja) | 2006-01-27 | 2017-03-08 | ノバルティス アーゲー | 血球凝集素およびマトリックスタンパク質を含むインフルエンザウイルスワクチン |
FR2898909A1 (fr) | 2006-03-24 | 2007-09-28 | Agronomique Inst Nat Rech | Combinaison de marqueurs de cellules aviaires |
EP2382987A1 (de) | 2006-03-24 | 2011-11-02 | Novartis Vaccines and Diagnostics GmbH | Lagerung von Influenza-Impfstoffen ohne Kühlung |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
EP2054507A1 (de) | 2006-08-09 | 2009-05-06 | Vivalis | Verfahren zur herstellung transgener vögel unter verwendung embryonaler stammzellen |
EP2066345B1 (de) | 2006-09-11 | 2015-02-25 | Novartis AG | Herstellung von influenza-virus-impfstoffen ohne verwendung von eiern |
PL2121011T3 (pl) | 2006-12-06 | 2014-10-31 | Novartis Ag | Szczepionki zawierające antygeny czterech szczepów wirusa grypy |
CN100443588C (zh) * | 2006-12-11 | 2008-12-17 | 中国农业科学院北京畜牧兽医研究所 | 静宁鸡胚成纤维细胞系及其培养方法 |
EP1985305A1 (de) * | 2007-04-24 | 2008-10-29 | Vivalis | Aus Entenembryonen gewonnene Stammzellkulturen zur Herstellung von Impfstoffen gegen Viren |
EP1995309A1 (de) * | 2007-05-21 | 2008-11-26 | Vivalis | Rekombinante Proteinproduktion in EBx -Vogelzellen |
SI2185191T1 (sl) | 2007-06-27 | 2012-12-31 | Novartis Ag | Cepiva proti influenci z majhnimi dodatki |
WO2009004016A1 (en) * | 2007-07-03 | 2009-01-08 | Transgene S.A. | Immortalized avian cell lines |
US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
WO2009081172A1 (en) | 2007-12-24 | 2009-07-02 | Novartis Ag | Assays for adsorbed influenza vaccines |
US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
RU2509803C2 (ru) * | 2008-02-25 | 2014-03-20 | Бакстер Интернэшнл Инк. | Способ получения непрерывных клеточных линий и их применение |
NZ587798A (en) | 2008-03-18 | 2013-06-28 | Novartis Ag | Improvements in the preparation of influenza virus vaccine antigens utilising a phosphate buffer |
WO2009132195A1 (en) * | 2008-04-23 | 2009-10-29 | Michigan State University | Immortal avian cell line and methods of use |
WO2010081890A1 (en) | 2009-01-19 | 2010-07-22 | Innate Pharma | Anti-kir3d antibodies |
ES2552383T3 (es) | 2009-02-10 | 2015-11-27 | Novartis Ag | Regímenes de vacuna de la gripe para cepas asociadas a pandemias |
EP2396031A1 (de) | 2009-02-10 | 2011-12-21 | Novartis AG | Grippeimpfstoffe mit erhöhten h3-antigen-mengen |
CA2751379C (en) | 2009-02-10 | 2018-06-12 | Novartis Ag | Influenza vaccines with reduced amounts of squalene |
USH2284H1 (en) | 2009-04-27 | 2013-09-03 | Novartis Ag | Vaccines for protecting against influenza |
PL3178490T3 (pl) | 2009-07-15 | 2022-08-01 | Glaxosmithkline Biologicals S.A. | Kompozycje białka f rsv i sposoby ich wytwarzania |
SG178904A1 (en) | 2009-09-10 | 2012-04-27 | Novartis Ag | Combination vaccines against respiratory tract diseases |
GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
CA2725435C (en) | 2009-12-15 | 2023-01-03 | University Of Saskatchewan | Vaccines for inclusion body hepatitis |
US20120309056A1 (en) | 2010-02-04 | 2012-12-06 | Leon Arnaud | Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells |
FR2956409A1 (fr) | 2010-02-15 | 2011-08-19 | Univ Claude Bernard Lyon | Procedes pour optimiser la production virale par l'inactivation ou l'inhibition du gene hipk2 et cellules modifiees pour la production virale |
EP2545172B2 (de) | 2010-03-08 | 2017-12-06 | Novartis AG | Methode zum testen von intrazellulären pathogenen |
BR112012025364A2 (pt) | 2010-04-07 | 2015-09-22 | Novartis Ag | método para geração de partícula semelhante a vírus de parvovírus b19 |
EP2374816B1 (de) | 2010-04-07 | 2016-09-28 | Agency For Science, Technology And Research | Bindemoleküle gegen Chikungunya-Virus und Verwendungen davon |
US9441032B2 (en) | 2010-04-07 | 2016-09-13 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
EA201291179A1 (ru) | 2010-05-06 | 2013-04-30 | Новартис Аг | Органические пероксидные соединения для инактивации микроорганизмов |
CA2800150C (en) | 2010-05-21 | 2018-09-04 | Novartis Ag | Influenza virus reassortment method |
EA201291404A1 (ru) | 2010-06-01 | 2013-05-30 | Новартис Аг | Концентрация и лиофилизация вакцинных антигенов гриппа |
US20130224245A1 (en) | 2010-06-01 | 2013-08-29 | Novartis Ag | Concentration of vaccine antigens without lyophilization |
EP2591097A1 (de) | 2010-07-06 | 2013-05-15 | Novartis AG | Immunogene zusammensetzungen aus norovirus und verfahren |
GB201011502D0 (en) | 2010-07-08 | 2010-08-25 | Glaxosmithkline Biolog Sa | Novel process |
ES2531577T3 (es) | 2010-08-20 | 2015-03-17 | Novartis Ag | Conjuntos de agujas para la administración de vacuna soluble contra la gripe |
DK2614141T3 (da) | 2010-09-07 | 2019-09-09 | Technion Res & Dev Foundation | Hidtil ukendte fremgangsmåder og dyrkningsmedier til dyrkning af pluripotente stamceller |
FR2967072B1 (fr) | 2010-11-05 | 2013-03-29 | Univ Dundee | Procede pour ameliorer la production de virus et semences vaccinales influenza |
WO2012095514A1 (en) | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
EP2667892B1 (de) | 2011-01-26 | 2019-03-27 | GlaxoSmithKline Biologicals SA | Rsv-immunisierungstherapie |
SMT201700569T1 (it) | 2011-05-13 | 2018-01-11 | Glaxosmithkline Biologicals Sa | Antigeni f di pre-fusione di rsv |
US11896636B2 (en) | 2011-07-06 | 2024-02-13 | Glaxosmithkline Biologicals Sa | Immunogenic combination compositions and uses thereof |
WO2013006842A2 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic compositions and uses thereof |
TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Hbv聚合酶突變體 |
TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
WO2013054199A2 (en) | 2011-10-12 | 2013-04-18 | Novartis Ag | Cmv antigens and uses thereof |
GB201216121D0 (en) | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
JP2014532620A (ja) | 2011-10-20 | 2014-12-08 | ノバルティス アーゲー | 小児の初回免疫のためのアジュバント添加インフルエンザbウイルスワクチン |
EP2660316A1 (de) | 2012-05-02 | 2013-11-06 | Helmholtz-Zentrum für Infektionsforschung GmbH | Vogelzelllinie und deren Verwendung bei der Herstellung eines Proteins |
JP2015522580A (ja) | 2012-07-06 | 2015-08-06 | ノバルティス アーゲー | 免疫学的組成物およびその使用 |
CN104640564B (zh) | 2012-07-10 | 2020-08-04 | 特兰斯吉恩股份有限公司 | 分枝杆菌抗原疫苗 |
WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
CN104853769A (zh) | 2012-11-20 | 2015-08-19 | 葛兰素史密丝克莱恩生物有限公司 | Rsv f融合前三聚体 |
US20140255447A1 (en) * | 2013-03-05 | 2014-09-11 | Biomune Company | Production of avian embryo cells |
FR3008992A1 (fr) * | 2013-07-25 | 2015-01-30 | Agronomique Inst Nat Rech | Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires |
RU2695462C2 (ru) | 2014-01-09 | 2019-07-23 | Трансген Са | Гибридизация гетероолигомерных микобактериальных антигенов |
EP2974739A1 (de) | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF-Trimerisierungsdomänen |
EP3031822A1 (de) | 2014-12-08 | 2016-06-15 | Novartis AG | Cytomegalovirus-Antigene |
AU2015367385B2 (en) | 2014-12-17 | 2021-05-27 | Fundación Para La Investigación Mèdica Aplicada | Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson disease |
ES2784264T3 (es) | 2014-12-17 | 2020-09-23 | Fundacion Para La Investig Medica Aplicada | Construcciones de ácido nucleico y vectores de terapia génica para su uso en el tratamiento de la enfermedad de Wilson y otras afecciones |
EP3047856A1 (de) | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv-antigene und ihre verwendungen |
EP3313439A2 (de) | 2015-06-26 | 2018-05-02 | Seqirus UK Limited | Antigenetisch angepasste influenza-impfstoffe |
EP3320343B1 (de) | 2015-07-07 | 2020-09-02 | Seqirus UK Limited | Verfahren zur quantifizierung von immunogenem hämagglutinin |
ES3001108T3 (es) | 2017-03-30 | 2025-03-04 | Univ Queensland | Moléculas quiméricas y usos de las mismas |
EP3687561A4 (de) | 2017-09-01 | 2021-06-09 | The Australian National University | Immunregulatorische moleküle und deren verwendung |
MA50942A (fr) | 2017-12-01 | 2020-10-07 | Encoded Therapeutics Inc | Protéines de liaison à l'adn modifiées |
WO2019219649A1 (en) | 2018-05-14 | 2019-11-21 | Vivet Therapeutics | Gene therapy vectors comprising s/mar sequences |
AU2019276261A1 (en) | 2018-05-30 | 2020-12-03 | Institute For Research In Biomedicine | Engineering B lymphocytes by utilizing endogenous activation-induced cytidine deaminase |
WO2020012037A1 (en) | 2018-07-13 | 2020-01-16 | Valneva Se | Method for rescuing and producing a virus in avian cells |
EP4223320B1 (de) | 2018-10-12 | 2025-06-18 | Vivet Therapeutics | Codonoptimiertes transgen zur behandlung von progressiver vertrauter intrahepatischer cholestase typ 3 (pfic3) |
US20220002751A1 (en) | 2018-11-07 | 2022-01-06 | Vivet Therapeutics | Codon-optimized abcb11 transgene for the treatment of progressive familial intrahepatic cholestasis type 2 (pfic2) |
JP7532360B2 (ja) | 2018-11-16 | 2024-08-13 | エンコーデッド セラピューティクス, インコーポレイテッド | ウィルソン病を処置するための組成物および方法 |
CA3120166A1 (en) * | 2018-11-23 | 2020-05-28 | Valneva Se | Food products comprising avian stem cells |
JP7664856B2 (ja) | 2019-05-22 | 2025-04-18 | ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド | ヒト多能性細胞を培養する方法 |
CN114174520B (zh) | 2019-05-29 | 2025-07-08 | 编码治疗公司 | 用于选择性基因调节的组合物和方法 |
JP2022544740A (ja) | 2019-07-02 | 2022-10-21 | フンダシオン・パラ・ラ・インベスティガシオン・メディカ・アプリカダ | cPLA2e誘導剤及びその使用 |
EP3999108A1 (de) | 2019-07-21 | 2022-05-25 | GlaxoSmithKline Biologicals S.A. | Therapeutischer viraler impfstoff |
US20230201334A1 (en) | 2019-07-24 | 2023-06-29 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
JP2022548179A (ja) * | 2019-09-10 | 2022-11-16 | バイタル ミート | 食品製造のための鳥類幹細胞 |
MX2022006005A (es) | 2019-11-18 | 2022-10-27 | Seqirus Pty Ltd | Metodo para producir virus de la influenza reagrupados. |
JP2023536080A (ja) | 2020-08-06 | 2023-08-23 | ファンダシオン パラ ラ インベスティガシオン メディカ アプリカダ | 遺伝子治療によるアルツハイマー病などのタウオパチーの治療に使用するためのウイルス粒子 |
US20230265456A1 (en) | 2020-08-10 | 2023-08-24 | Fundacion Para La Investigacion Medica Aplicada | Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis |
MX2023003994A (es) | 2020-10-09 | 2023-04-24 | UCB Biopharma SRL | Construcciones de acido nucleico, vectores virales y particulas virales. |
WO2022136616A1 (en) | 2020-12-23 | 2022-06-30 | Vivet Therapeutics | Minimal bile acid inducible promoters for gene therapy |
EP4032547A1 (de) | 2021-01-20 | 2022-07-27 | GlaxoSmithKline Biologicals S.A. | Hsv1 fce abgeleitete fragemente zur hsv therapie |
AR127455A1 (es) | 2021-10-28 | 2024-01-24 | UCB Biopharma SRL | Constructos de ácido nucleico, vectores víricos y partículas víricas |
EP4469078A1 (de) | 2022-01-28 | 2024-12-04 | GlaxoSmithKline Biologicals S.A. | Modifizierte humane cytomegalovirus proteine |
CN114480286B (zh) * | 2022-02-16 | 2024-05-31 | 上海健士拜生物科技有限公司 | 无血清悬浮型lmh细胞系及其制备方法和应用 |
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-
2002
- 2002-03-08 FR FR0202945A patent/FR2836924B1/fr not_active Expired - Lifetime
-
2003
- 2003-03-07 AT AT03725273T patent/ATE408004T1/de active
- 2003-03-07 DE DE60323468T patent/DE60323468D1/de not_active Expired - Lifetime
- 2003-03-07 EP EP03725273A patent/EP1483369B1/de not_active Expired - Lifetime
- 2003-03-07 SI SI200331354T patent/SI1483369T1/sl unknown
- 2003-03-07 ES ES03725273T patent/ES2312775T3/es not_active Expired - Lifetime
- 2003-03-07 DK DK03725273T patent/DK1483369T3/da active
- 2003-03-07 CN CNB038101203A patent/CN100562567C/zh not_active Expired - Fee Related
- 2003-03-07 AU AU2003227820A patent/AU2003227820B2/en not_active Expired
- 2003-03-07 CA CA2478125A patent/CA2478125C/fr not_active Expired - Fee Related
- 2003-03-07 PT PT03725273T patent/PT1483369E/pt unknown
- 2003-03-07 EP EP08163979.1A patent/EP1992687B1/de not_active Expired - Lifetime
- 2003-03-07 CN CN2009101796309A patent/CN101676388B/zh not_active Expired - Lifetime
- 2003-03-07 WO PCT/FR2003/000735 patent/WO2003076601A1/fr active IP Right Grant
- 2003-03-07 JP JP2003574808A patent/JP5025888B2/ja not_active Expired - Fee Related
- 2003-07-24 US US10/625,847 patent/US20040058441A1/en not_active Abandoned
-
2009
- 2009-01-08 US US12/350,781 patent/US20090239297A1/en not_active Abandoned
-
2010
- 2010-03-03 US US12/717,096 patent/US9382513B2/en not_active Expired - Fee Related
-
2011
- 2011-08-09 US US13/206,056 patent/US20110294209A1/en not_active Abandoned
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2012
- 2012-02-09 JP JP2012026135A patent/JP5784521B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1992687A2 (de) | 2008-11-19 |
US20100221825A1 (en) | 2010-09-02 |
CA2478125A1 (fr) | 2003-09-18 |
FR2836924B1 (fr) | 2005-01-14 |
JP2005525803A (ja) | 2005-09-02 |
US20120070893A9 (en) | 2012-03-22 |
JP5784521B2 (ja) | 2015-09-24 |
EP1483369A1 (de) | 2004-12-08 |
ATE408004T1 (de) | 2008-09-15 |
FR2836924A1 (fr) | 2003-09-12 |
SI1483369T1 (sl) | 2008-12-31 |
CN101676388B (zh) | 2013-09-04 |
JP5025888B2 (ja) | 2012-09-12 |
JP2012110344A (ja) | 2012-06-14 |
AU2003227820B2 (en) | 2008-04-03 |
WO2003076601A1 (fr) | 2003-09-18 |
ES2312775T3 (es) | 2009-03-01 |
DE60323468D1 (de) | 2008-10-23 |
CN101676388A (zh) | 2010-03-24 |
WO2003076601A8 (fr) | 2005-05-12 |
US9382513B2 (en) | 2016-07-05 |
AU2003227820A1 (en) | 2003-09-22 |
EP1483369B1 (de) | 2008-09-10 |
CN1649999A (zh) | 2005-08-03 |
HK1142094A1 (en) | 2010-11-26 |
US20090239297A1 (en) | 2009-09-24 |
CN100562567C (zh) | 2009-11-25 |
EP1992687A3 (de) | 2009-03-25 |
CA2478125C (fr) | 2013-05-07 |
US20040058441A1 (en) | 2004-03-25 |
PT1483369E (pt) | 2008-12-17 |
EP1992687B1 (de) | 2019-06-26 |
US20110294209A1 (en) | 2011-12-01 |
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