[go: up one dir, main page]

DK1483369T3 - Fuglecellelinier til fremstiling af stoffer af interesse - Google Patents

Fuglecellelinier til fremstiling af stoffer af interesse

Info

Publication number
DK1483369T3
DK1483369T3 DK03725273T DK03725273T DK1483369T3 DK 1483369 T3 DK1483369 T3 DK 1483369T3 DK 03725273 T DK03725273 T DK 03725273T DK 03725273 T DK03725273 T DK 03725273T DK 1483369 T3 DK1483369 T3 DK 1483369T3
Authority
DK
Denmark
Prior art keywords
cell lines
serum
growth factors
medium
feeder layer
Prior art date
Application number
DK03725273T
Other languages
English (en)
Inventor
Fabienne Guehenneux
Bertrand Pain
Original Assignee
Vivalis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivalis filed Critical Vivalis
Application granted granted Critical
Publication of DK1483369T3 publication Critical patent/DK1483369T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/92Medium free of human- or animal-derived components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95Protein-free medium and culture conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK03725273T 2002-03-08 2003-03-07 Fuglecellelinier til fremstiling af stoffer af interesse DK1483369T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0202945A FR2836924B1 (fr) 2002-03-08 2002-03-08 Lignees de cellules aviaires utiles pour la production de substances d'interet
PCT/FR2003/000735 WO2003076601A1 (fr) 2002-03-08 2003-03-07 Lignées de cellules aviaires utiles pour la production de substances d'intérêt

Publications (1)

Publication Number Publication Date
DK1483369T3 true DK1483369T3 (da) 2008-12-01

Family

ID=27763651

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03725273T DK1483369T3 (da) 2002-03-08 2003-03-07 Fuglecellelinier til fremstiling af stoffer af interesse

Country Status (15)

Country Link
US (4) US20040058441A1 (da)
EP (2) EP1992687B1 (da)
JP (2) JP5025888B2 (da)
CN (2) CN101676388B (da)
AT (1) ATE408004T1 (da)
AU (1) AU2003227820B2 (da)
CA (1) CA2478125C (da)
DE (1) DE60323468D1 (da)
DK (1) DK1483369T3 (da)
ES (1) ES2312775T3 (da)
FR (1) FR2836924B1 (da)
HK (1) HK1142094A1 (da)
PT (1) PT1483369E (da)
SI (1) SI1483369T1 (da)
WO (1) WO2003076601A1 (da)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7445924B2 (en) * 2000-11-23 2008-11-04 Bavarian Nordic A/S Modified Vaccinia Ankara virus variant and cultivation method
US20060191026A1 (en) 2005-02-18 2006-08-24 Origen Therapeutics, Inc. Tissue specific expression of antibodies in chickens
US7145057B2 (en) 2002-02-01 2006-12-05 Origen Therapeutics, Inc. Chimeric bird from embryonic stem cells
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
DE60320520T3 (de) * 2002-09-05 2019-05-09 Bavarian Nordic A/S Verfahren zur amplifikation von einem poxvirus in serumfreien verhältnissen
CA2510229A1 (en) * 2002-12-13 2004-07-08 Aventis Pasteur, Inc. Production of alvac on avian embryonic stem cells
DE602004027141D1 (de) * 2003-07-22 2010-06-24 Vivalis Produktion von poxviren mit adhärenten oder nicht adhärenten vogelzellinien
EP1500699A1 (en) * 2003-07-22 2005-01-26 Vivalis Production of vaccinia virus with adherent or non adherent avian cell lines
WO2005028634A2 (en) * 2003-09-18 2005-03-31 Emory University Improved mva vaccines
WO2006078294A2 (en) 2004-05-21 2006-07-27 Novartis Vaccines And Diagnostics Inc. Alphavirus vectors for respiratory pathogen vaccines
WO2006027698A1 (en) 2004-09-09 2006-03-16 Novartis Vaccines And Diagnostics Gmbh & Co Kg. Decreasing potential iatrogenic risks associated with influenza vaccines
AU2005314563B2 (en) 2004-11-03 2011-06-30 Seqirus UK Limited Influenza vaccination
FR2878860A1 (fr) * 2004-12-08 2006-06-09 Vivalis Sa Lignees de cellules souches humaines derivees de cellules es et utilisations pour la production de vaccins et de proteines recombinantes
AU2011253998B2 (en) * 2005-04-11 2014-04-24 Valneva Process of manufacturing viral vaccines in suspension avian embryonic derived stem cell lines
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
CA2627971A1 (en) 2005-11-01 2007-05-10 Novartis Vaccines And Diagnostics Gmbh & Co Kg. Cell-derived viral vaccines with low levels of residual cell dna by beta-propiolactone treatment
NZ567981A (en) 2005-11-04 2011-10-28 Novartis Vaccines & Diagnostic Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
CN102755645A (zh) 2005-11-04 2012-10-31 诺华疫苗和诊断有限公司 佐剂配制的包含细胞因子诱导剂的流感疫苗
JP2009514841A (ja) 2005-11-04 2009-04-09 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル 粒子状アジュバントと免疫増強物質との組合せを含むインフルエンザワクチン
EP1951302A2 (en) 2005-11-04 2008-08-06 Novartis Vaccines and Diagnostics S.r.l. Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
CA2628158C (en) 2005-11-04 2015-12-15 Novartis Vaccines And Diagnostics S.R.L. Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines
PL2478916T3 (pl) 2006-01-27 2020-11-16 Seqirus UK Limited Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy
AU2007231027B2 (en) 2006-03-24 2013-10-03 Novartis Influenza Vaccines Marburg Gmbh Storage of influenza vaccines without refrigeration
FR2898909A1 (fr) 2006-03-24 2007-09-28 Agronomique Inst Nat Rech Combinaison de marqueurs de cellules aviaires
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
MX2009001477A (es) 2006-08-09 2009-02-18 Vivalis Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas.
EP2497495B3 (en) 2006-09-11 2021-02-17 Seqirus UK Limited Making influenza virus vaccines without using eggs
SG177141A1 (en) 2006-12-06 2012-01-30 Novartis Ag Vaccines including antigen from four strains of influenza virus
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
EP1985305A1 (en) 2007-04-24 2008-10-29 Vivalis Duck embryonic derived stem cell lines for the production of viral vaccines
EP1995309A1 (en) * 2007-05-21 2008-11-26 Vivalis Recombinant protein production in avian EBx® cells
CA2692200A1 (en) 2007-06-27 2008-12-31 Novartis Ag Low-additive influenza vaccines
AU2008270317B2 (en) * 2007-07-03 2013-12-05 Transgene S.A. Immortalized avian cell lines
US20090028831A1 (en) * 2007-07-23 2009-01-29 University Of Kentucky Research Foundation Stem cell regulator, compositions and methods of use
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
CN101971030A (zh) 2007-12-24 2011-02-09 诺华有限公司 流感吸附疫苗的试验
US8506966B2 (en) 2008-02-22 2013-08-13 Novartis Ag Adjuvanted influenza vaccines for pediatric use
RU2509803C2 (ru) 2008-02-25 2014-03-20 Бакстер Интернэшнл Инк. Способ получения непрерывных клеточных линий и их применение
AU2009227674C1 (en) 2008-03-18 2015-01-29 Seqirus UK Limited Improvements in preparation of influenza virus vaccine antigens
US8716016B2 (en) * 2008-04-23 2014-05-06 Board Of Trustees Of Michigan State University Immortal avian cell line and methods of use
DK2379598T3 (da) 2009-01-19 2015-06-15 Innate Pharma Anti-kir3d-antistoffer
JP5642712B2 (ja) 2009-02-10 2014-12-17 ノバルティス アーゲー 少ない量のスクアレンを含むインフルエンザワクチン
JP2012517416A (ja) 2009-02-10 2012-08-02 ノバルティス アーゲー 増加した量のh3抗原を含むインフルエンザワクチン
EA201171032A1 (ru) 2009-02-10 2012-02-28 Новартис Аг Схемы лечения с помощью вакцины против гриппа, связанного с пандемическими штаммами
EP2424565A1 (en) 2009-04-27 2012-03-07 Novartis AG Adjuvanted vaccines for protecting against influenza
EP2453918B1 (en) 2009-07-15 2015-12-16 GlaxoSmithKline Biologicals S.A. Rsv f protein compositions and methods for making same
CN102695523A (zh) 2009-09-10 2012-09-26 诺华有限公司 针对呼吸道疾病的组合疫苗
GB0918830D0 (en) 2009-10-27 2009-12-09 Glaxosmithkline Biolog Niederl Process
GB0919117D0 (en) 2009-10-30 2009-12-16 Glaxosmithkline Biolog Sa Process
CA2725435C (en) 2009-12-15 2023-01-03 University Of Saskatchewan Vaccines for inclusion body hepatitis
EP2531592A1 (en) 2010-02-04 2012-12-12 Vivalis Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
FR2956409A1 (fr) 2010-02-15 2011-08-19 Univ Claude Bernard Lyon Procedes pour optimiser la production virale par l'inactivation ou l'inhibition du gene hipk2 et cellules modifiees pour la production virale
EP2545172B2 (en) 2010-03-08 2017-12-06 Novartis AG Methods of testing for intracellular pathogens
WO2011124635A1 (en) 2010-04-07 2011-10-13 Humalys Binding molecules against chikungunya virus and uses thereof
US9744228B2 (en) 2010-04-07 2017-08-29 Norvartis Ag Method for generating a parvovirus B19 virus-like particle
EP2374816B1 (en) 2010-04-07 2016-09-28 Agency For Science, Technology And Research Binding molecules against Chikungunya virus and uses thereof
AU2011249487C1 (en) 2010-05-06 2015-05-14 Novartis Ag Organic peroxide compounds for microorganism inactivation
US8945904B2 (en) 2010-05-21 2015-02-03 Novartis Ag Influenza virus reassortment
KR20130081659A (ko) 2010-06-01 2013-07-17 노파르티스 아게 인플루엔자 백신 항원의 농축 및 동결건조
EP2575872B1 (en) 2010-06-01 2020-08-19 Seqirus UK Limited Concentration of influenza vaccine antigens without lyophilization
JP2013533745A (ja) 2010-07-06 2013-08-29 ノバルティス アーゲー ノロウイルスに由来する免疫原性組成物および方法
GB201011502D0 (en) 2010-07-08 2010-08-25 Glaxosmithkline Biolog Sa Novel process
AU2011290471B2 (en) 2010-08-20 2015-08-20 Novartis Ag Soluble needle arrays for delivery of influenza vaccines
CA2810488A1 (en) 2010-09-07 2012-03-15 Technion Research & Development Foundation Limited Novel methods and culture media for culturing pluripotent stem cells
FR2967072B1 (fr) 2010-11-05 2013-03-29 Univ Dundee Procede pour ameliorer la production de virus et semences vaccinales influenza
WO2012095514A1 (en) 2011-01-14 2012-07-19 Vivalis Recombinant protein production system
AU2012211278B2 (en) 2011-01-26 2016-11-10 Glaxosmithkline Biologicals Sa RSV immunization regimen
SI2707385T1 (en) 2011-05-13 2018-01-31 Glaxosmithkline Biologicals Sa Pregnant RSV F antigens
US11058762B2 (en) 2011-07-06 2021-07-13 Glaxosmithkline Biologicals Sa Immunogenic compositions and uses thereof
CA2840989A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic combination compositions and uses thereof
TWI623618B (zh) 2011-07-12 2018-05-11 傳斯堅公司 Hbv聚合酶突變體
TW201321016A (zh) 2011-09-29 2013-06-01 Transgene Sa 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二)
TW201318637A (zh) 2011-09-29 2013-05-16 Transgene Sa 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一)
EP2766385A2 (en) 2011-10-12 2014-08-20 Novartis AG Cmv antigens and uses thereof
GB201216121D0 (en) 2012-09-10 2012-10-24 Novartis Ag Sample quantification by disc centrifugation
EP2768528A1 (en) 2011-10-20 2014-08-27 Novartis AG Adjuvanted influenza b virus vaccines for pediatric priming
EP2660316A1 (en) 2012-05-02 2013-11-06 Helmholtz-Zentrum für Infektionsforschung GmbH Avian cell line and its use in production of protein
CN104853770A (zh) 2012-07-06 2015-08-19 诺华股份有限公司 免疫原性组合物及其应用
CN104640564B (zh) 2012-07-10 2020-08-04 特兰斯吉恩股份有限公司 分枝杆菌抗原疫苗
WO2014009433A1 (en) 2012-07-10 2014-01-16 Transgene Sa Mycobacterium resuscitation promoting factor for use as adjuvant
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
CA2890135A1 (en) 2012-11-20 2014-05-30 Glaxosmithkline Biologicals S.A. Rsv f prefusion trimers
US20140255447A1 (en) * 2013-03-05 2014-09-11 Biomune Company Production of avian embryo cells
FR3008992A1 (fr) * 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
RU2695462C2 (ru) 2014-01-09 2019-07-23 Трансген Са Гибридизация гетероолигомерных микобактериальных антигенов
EP2974739A1 (en) 2014-07-15 2016-01-20 Novartis AG RSVF trimerization domains
EP3031822A1 (en) 2014-12-08 2016-06-15 Novartis AG Cytomegalovirus antigens
SG11201704690TA (en) 2014-12-17 2017-07-28 Fundación Para La Investigación Mèdica Aplicada Nucleic acid constructs and gene therapy vectors for use in the treatment of wilson disease
ES2784264T3 (es) 2014-12-17 2020-09-23 Fundacion Para La Investig Medica Aplicada Construcciones de ácido nucleico y vectores de terapia génica para su uso en el tratamiento de la enfermedad de Wilson y otras afecciones
EP3047856A1 (en) 2015-01-23 2016-07-27 Novartis AG Cmv antigens and uses thereof
EP3313439A2 (en) 2015-06-26 2018-05-02 Seqirus UK Limited Antigenically matched influenza vaccines
CN111896742B (zh) 2015-07-07 2024-08-06 思齐乐 流感效力试验
IL269534B2 (en) 2017-03-30 2025-01-01 Univ Queensland Chimeric molecules and their uses
WO2019040994A1 (en) 2017-09-01 2019-03-07 The Australian National University IMMUNOREGULATOR MOLECULES AND USES THEREOF
AU2018375192B2 (en) 2017-12-01 2023-11-09 Encoded Therapeutics, Inc. Engineered DNA binding proteins
US20210180084A1 (en) 2018-05-14 2021-06-17 Vivet Therapeutics Gene therapy vectors comprising s/mar sequences
CA3100112A1 (en) 2018-05-30 2019-12-05 Institute For Research In Biomedicine Engineering b lymphocytes by utilizing endogenous activation-induced cytidine deaminase
EP3820884A1 (en) 2018-07-13 2021-05-19 Valneva SE Method for rescuing and producing a virus in avian cells
KR20210086638A (ko) 2018-10-12 2021-07-08 비베트 테라퓨틱스 진행성 가족성 간내 담즙정체 3형 (pfic3)의 치료를 위한 코돈-최적화 전이유전자
CN112955186A (zh) 2018-11-07 2021-06-11 维韦特治疗公司 用于治疗进行性家族性肝内胆汁淤积症2型(pfic2)的密码子优化的abcb11转基因
JP7532360B2 (ja) 2018-11-16 2024-08-13 エンコーデッド セラピューティクス, インコーポレイテッド ウィルソン病を処置するための組成物および方法
KR20210094554A (ko) * 2018-11-23 2021-07-29 발네바 에스이 조류 줄기 세포를 포함하는 식품
WO2020234888A1 (en) 2019-05-22 2020-11-26 Hadasit Medical Research Services And Development Ltd. Methods of culturing human pluripotent cells
CA3141900C (en) 2019-05-29 2023-06-06 Encoded Therapeutics, Inc. Compositions and methods for selective gene regulation
US20220233722A1 (en) 2019-07-02 2022-07-28 Fundacion Para La Investigacion Medica Aplicada cPLA2e INDUCING AGENTS AND USES THEREOF
BR112022000710A2 (pt) 2019-07-21 2022-03-22 Glaxosmithkline Biologicals Sa Vacina viral terapêutica
US20230201334A1 (en) 2019-07-24 2023-06-29 Glaxosmithkline Biologicals Sa Modified human cytomegalovirus proteins
WO2021048325A1 (en) * 2019-09-10 2021-03-18 Vital Meat Avian stem cells for the production of a food product
WO2021099419A1 (en) 2019-11-18 2021-05-27 Seqirus UK Limited Method for producing reassortant influenza viruses
MX2023000968A (es) 2020-08-06 2023-03-01 Fundacion Para La Investig Medica Aplicada Particulas virales para usarse en el tratamiento contra tauopatias tales como enfermedad de alzheimer mediante terapia genica.
US20230265456A1 (en) 2020-08-10 2023-08-24 Fundacion Para La Investigacion Medica Aplicada Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis
PE20230987A1 (es) 2020-10-09 2023-06-21 UCB Biopharma SRL Construcciones de acido nucleico, vectores virales y particulas virales
EP4267197A1 (en) 2020-12-23 2023-11-01 Vivet Therapeutics Minimal bile acid inducible promoters for gene therapy
EP4032547A1 (en) 2021-01-20 2022-07-27 GlaxoSmithKline Biologicals S.A. Hsv1 fce derived fragements for the treatment of hsv
JP2024543001A (ja) 2021-10-28 2024-11-19 ユーシービー バイオファルマ エスアールエル 核酸構築物、ウイルスベクターおよびウイルス粒子
US20250101067A1 (en) 2022-01-28 2025-03-27 Glaxosmithkline Biologicals Sa Modified human cytomegalovirus proteins
CN114480286B (zh) * 2022-02-16 2024-05-31 上海健士拜生物科技有限公司 无血清悬浮型lmh细胞系及其制备方法和应用
CN116656628A (zh) * 2023-07-31 2023-08-29 深圳市卫光生物制品股份有限公司 一种痘病毒载体疫苗的制备方法
CN118956737A (zh) * 2024-07-17 2024-11-15 广州沃亘生物科技有限公司 一种长期维持df-1细胞活力的培养基及其用途

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388298A (en) 1982-07-14 1983-06-14 The United States Of America As Represented By The Secretary Of Agriculture Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced
JP2740320B2 (ja) 1988-08-04 1998-04-15 アムラド・コーポレイション・リミテッド 胚幹細胞のインビトロ増殖
US5162215A (en) * 1988-09-22 1992-11-10 Amgen Inc. Method of gene transfer into chickens and other avian species
US5388680A (en) 1990-10-09 1995-02-14 Intellicall, Inc. Coin handling system with an improved coin chute
WO1993001276A1 (en) 1991-07-12 1993-01-21 Smithkline Beecham Corporation Continuous cell line and vaccine against avian coccidia
JPH05227947A (ja) 1992-01-14 1993-09-07 Rikagaku Kenkyusho 鳥類原始生殖細胞の分離方法
AU3597093A (en) 1992-01-27 1993-09-01 Embrex Inc. Gene transfer in poultry by introduction of embryo cells (in ovo)
US5340740A (en) 1992-05-15 1994-08-23 North Carolina State University Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
WO1994003585A1 (en) 1992-08-04 1994-02-17 Commonwealth Scientific And Industrial Research Organisation A method for maintaining embryonic stem cells and avian factor useful for same
US5453357A (en) * 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
US5589458A (en) * 1992-11-13 1996-12-31 Thomas Jefferson University Compounds that inhibit T cell proliferation and methods for using the same
FR2726003B1 (fr) * 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
US5989805A (en) 1995-10-27 1999-11-23 Board Of Trustees Operating Michigan State University Immortal avian cell line to grow avian and animal viruses to produce vaccines
FR2749022B1 (fr) 1996-05-23 2001-06-01 Rhone Merieux Cellules aviaires immortelles
US5691200A (en) 1996-07-03 1997-11-25 The United States Of America As Represented By The Secretary Of Agriculture Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes and method to produce immortalized cells
US5672485A (en) 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth
US5830723A (en) 1996-08-13 1998-11-03 Regents Of The University Of Minnesota Method for immortalizing chicken cells
DE69738806D1 (de) 1996-10-10 2008-08-14 Invitrogen Corp Tierzellkulturmedium mit pflanzlichen nährstoffen
ATE271122T1 (de) * 1996-11-12 2004-07-15 Pfizer Attenuierter lebender neospora impfstoff
AU738357B2 (en) * 1997-08-04 2001-09-13 University Of Massachusetts Production of avian embryonic germ (EG) cell lines by prolonged culturing of PGCS, use thereof for cloning and chimerization
BR9811830A (pt) * 1997-08-04 2000-08-15 Univ Massachusetts Processo de cultivo que proporciona manutenção de células germinais primitivas de ave por perìodos prolongados, processo de produção de aves quiméricas, e, linhagem celular de pgc de ave
US6406909B1 (en) 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
WO2000047717A1 (en) * 1999-02-11 2000-08-17 Hanmi Pharm. Co., Ltd. Avian pluripotent embryonic germ cell line
ATE384120T1 (de) * 1999-08-27 2008-02-15 Invitrogen Corp Metallbindende verbindungen und deren verwendung in zusammensetzungen für zellkulturmedien
DE19947407C2 (de) 1999-10-01 2002-08-01 Bayerische Motoren Werke Ag Datenbussystem für Kraftfahrzeuge
WO2002086073A2 (en) * 2001-04-20 2002-10-31 Memorial Sloan-Kettering Cancer Center Generation of differentiated tissue from nuclear transfer embryonic stem cells and methods of use
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
EP1520008B1 (en) * 2002-07-09 2012-09-05 Baxter International Inc. Animal protein free media for cultivation of cells
DE602004027141D1 (de) * 2003-07-22 2010-06-24 Vivalis Produktion von poxviren mit adhärenten oder nicht adhärenten vogelzellinien
EP1500699A1 (en) 2003-07-22 2005-01-26 Vivalis Production of vaccinia virus with adherent or non adherent avian cell lines
KR100552844B1 (ko) * 2003-12-31 2006-02-21 동부아남반도체 주식회사 반도체 소자의 제조 방법
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
WO2007135133A1 (en) 2006-05-19 2007-11-29 Vivalis Avian cell lines derived from primordial germ cells useful for the production of substances of interest
MX2009001477A (es) * 2006-08-09 2009-02-18 Vivalis Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas.
EP1985305A1 (en) * 2007-04-24 2008-10-29 Vivalis Duck embryonic derived stem cell lines for the production of viral vaccines

Also Published As

Publication number Publication date
FR2836924B1 (fr) 2005-01-14
SI1483369T1 (sl) 2008-12-31
WO2003076601A8 (fr) 2005-05-12
JP2005525803A (ja) 2005-09-02
US20120070893A9 (en) 2012-03-22
CN101676388A (zh) 2010-03-24
AU2003227820B2 (en) 2008-04-03
AU2003227820A1 (en) 2003-09-22
JP5025888B2 (ja) 2012-09-12
EP1992687B1 (fr) 2019-06-26
US20110294209A1 (en) 2011-12-01
US9382513B2 (en) 2016-07-05
CN100562567C (zh) 2009-11-25
JP5784521B2 (ja) 2015-09-24
EP1992687A2 (fr) 2008-11-19
CA2478125C (fr) 2013-05-07
PT1483369E (pt) 2008-12-17
FR2836924A1 (fr) 2003-09-12
EP1992687A3 (fr) 2009-03-25
US20040058441A1 (en) 2004-03-25
CN1649999A (zh) 2005-08-03
WO2003076601A1 (fr) 2003-09-18
EP1483369B1 (fr) 2008-09-10
JP2012110344A (ja) 2012-06-14
US20090239297A1 (en) 2009-09-24
ATE408004T1 (de) 2008-09-15
ES2312775T3 (es) 2009-03-01
DE60323468D1 (de) 2008-10-23
CN101676388B (zh) 2013-09-04
HK1142094A1 (en) 2010-11-26
US20100221825A1 (en) 2010-09-02
EP1483369A1 (fr) 2004-12-08
CA2478125A1 (fr) 2003-09-18

Similar Documents

Publication Publication Date Title
DK1483369T3 (da) Fuglecellelinier til fremstiling af stoffer af interesse
GB2432846B (en) Medium and culture of embryonic stem cells
WO2006029198A3 (en) Culturing human embryonic stem cells
CO5590971A2 (es) Mejora en la calidad de producto en procesos de cultivo en celulas de mamiferos para la produccion de proteina
EA201270213A1 (ru) Способ получения полипептида или вируса, представляющих интерес, в непрерывной клеточной культуре
CY1110267T1 (el) Μεθοδος για την καλλιεργεια κυτταρων για την παραγωγη ουσιων
HK1093755A1 (en) Method for differentiating mesenchymal stem cell into neural cell
NZ591812A (en) Cell culture method to form aggregates
WO2009016078A3 (en) Method for culturing mammalian stem cells
DE60334025D1 (de) Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays
UA92157C2 (ru) Способ продуцирования гормона роста
ATE510004T1 (de) In-vitro-techniken zur verwendung mit stammzellen
GB2429211A (en) Feeder independent extended culture of embryonic stem cells
WO2004043401A3 (en) Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use
ATE517176T1 (de) Verfahren zur kultivierung von geschmackszellen aus säugern
ATE469209T1 (de) Herstellung und verwendung von basalmembranpartikeln
ATE449162T1 (de) Herstellung von tcr gamma delta t-zellen
HK1048135A1 (zh) 具增強細胞活力功能的高產量的細胞變動素(cytokine)
WO2004053080A3 (en) Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media
GB0217314D0 (en) Biomimetic urothelium
TH94723B (th) วิธีการสำหรับการผลิตเมทไทโอนีนโดยการเพาะเลี้ยงจุลชีพที่ถูกดัดแปลงเพื่อให้เพิ่มการผลิต