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DK142987A - Hidtil ukendte vitamin d-analoger - Google Patents

Hidtil ukendte vitamin d-analoger

Info

Publication number
DK142987A
DK142987A DK142987A DK142987A DK142987A DK 142987 A DK142987 A DK 142987A DK 142987 A DK142987 A DK 142987A DK 142987 A DK142987 A DK 142987A DK 142987 A DK142987 A DK 142987A
Authority
DK
Denmark
Prior art keywords
lower alkyl
hydroxyl
halogen
denotes hydrogen
optionally substituted
Prior art date
Application number
DK142987A
Other languages
English (en)
Other versions
DK142987D0 (da
DK166617B1 (da
Inventor
Martin John Calverley
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK142987(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519502A external-priority patent/GB8519502D0/en
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of DK142987D0 publication Critical patent/DK142987D0/da
Publication of DK142987A publication Critical patent/DK142987A/da
Application granted granted Critical
Publication of DK166617B1 publication Critical patent/DK166617B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK142987A 1985-08-02 1987-03-20 24-hydroxylerede d-vitamin-derivater og farmaceutiske praeparater indeholdende disse DK166617B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8519502 1985-08-02
GB858519502A GB8519502D0 (en) 1985-08-02 1985-08-02 Chemical compounds
PCT/DK1986/000081 WO1987000834A1 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
DK8600081 1986-07-14
PH3406186 1986-08-11
PH34061A PH25496A (en) 1985-08-02 1986-08-11 New vitamin d analogues

Publications (3)

Publication Number Publication Date
DK142987D0 DK142987D0 (da) 1987-03-20
DK142987A true DK142987A (da) 1987-03-20
DK166617B1 DK166617B1 (da) 1993-06-21

Family

ID=26289597

Family Applications (1)

Application Number Title Priority Date Filing Date
DK142987A DK166617B1 (da) 1985-08-02 1987-03-20 24-hydroxylerede d-vitamin-derivater og farmaceutiske praeparater indeholdende disse

Country Status (16)

Country Link
US (1) US4866048A (da)
EP (1) EP0227826B1 (da)
JP (1) JPH07100685B2 (da)
KR (1) KR940010767B1 (da)
AU (1) AU603340B2 (da)
CA (1) CA1307288C (da)
DE (1) DE3666587D1 (da)
DK (1) DK166617B1 (da)
ES (1) ES2000823A6 (da)
GR (1) GR862029B (da)
HK (1) HK63492A (da)
IE (1) IE58545B1 (da)
PH (1) PH25496A (da)
PT (1) PT83119B (da)
SG (1) SG64192G (da)
WO (1) WO1987000834A1 (da)

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US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
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US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
EP0503035B1 (en) * 1990-09-21 2001-12-12 Bone Care International, Inc. Novel 1alpha-hydroxy vitamin d4 and novel intermediates and analogues
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
ATE240736T1 (de) * 1991-01-08 2003-06-15 Bone Care Int Inc Verfahren zur herstellung von 1-alpha-24- dihydroxy-vitamin d2
US6166000A (en) * 1991-01-08 2000-12-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ATE143007T1 (de) * 1991-07-05 1996-10-15 Duphar Int Res Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
US5225569A (en) * 1991-08-09 1993-07-06 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
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US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
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US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
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JP4387465B2 (ja) * 1997-12-09 2009-12-16 中外製薬株式会社 ビタミンｄ３誘導体を含有するローション剤
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US6552009B2 (en) 1998-07-16 2003-04-22 Gentrix Llc Compositions and methods of treating abnormal cell proliferation
US20010002396A1 (en) * 1998-07-16 2001-05-31 Charles Achkar Compositions and methods of treating skin conditions
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CN100391464C (zh) * 2001-12-03 2008-06-04 诺瓦西股份有限公司 含活性维生素d化合物的药物组合物
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US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
EP1640449A4 (en) * 2003-06-27 2009-03-25 Asahi Chemical Ind CELL DIFFERENTIATION INHIBITOR AGENT, CELL CULTURE METHOD USING THE SAME, CULTURE MEDIUM AND CULTIVATED CELL LINE
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US7205006B2 (en) * 2003-09-25 2007-04-17 Prime Pharmaceutical Corporation Mahonia aquifolium extract, extraction process and pharmaceutical composition containing the same
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KR20070056001A (ko) * 2004-04-02 2007-05-31 레오 파마 에이/에스 비타민 ｄ 동족체의 합성에 유용한 중간체의 신규한제조방법
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US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
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CN103508999B (zh) * 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途
CN103694156B (zh) * 2014-01-07 2015-09-02 成都医路康医学技术服务有限公司 一种银屑病治疗药物钙泊三醇的制备方法
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
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CN107501150A (zh) * 2016-06-14 2017-12-22 江苏吉贝尔药业股份有限公司 两种他卡西醇中间体的制备方法
EP3490560B1 (en) 2016-07-29 2025-01-22 Janssen Pharmaceutica, N.V. Niraparib for use in a method of treating prostate cancer
CN110156836A (zh) * 2019-06-10 2019-08-23 成家钢 一种环丙基羰基亚甲基三苯基磷的制备方法
CN111662221B (zh) * 2020-06-29 2022-04-19 重庆华邦胜凯制药有限公司 一种卡泊三醇杂质的制备方法
CN115177586A (zh) * 2022-08-31 2022-10-14 江苏知原药业股份有限公司 一种卡泊三醇组合物

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Also Published As

Publication number Publication date
IE58545B1 (en) 1993-10-06
DK142987D0 (da) 1987-03-20
CA1307288C (en) 1992-09-08
DK166617B1 (da) 1993-06-21
AU6196186A (en) 1987-03-05
AU603340B2 (en) 1990-11-15
SG64192G (en) 1992-09-04
KR940010767B1 (ko) 1994-11-11
EP0227826A1 (en) 1987-07-08
WO1987000834A1 (en) 1987-02-12
PT83119A (en) 1986-09-01
DE3666587D1 (en) 1989-11-30
HK63492A (en) 1992-08-28
EP0227826B1 (en) 1989-10-25
GR862029B (en) 1986-12-24
ES2000823A6 (es) 1988-03-16
JPH07100685B2 (ja) 1995-11-01
IE861894L (en) 1987-02-02
KR870700600A (ko) 1987-12-30
JPS63500661A (ja) 1988-03-10
PH25496A (en) 1991-07-24
US4866048A (en) 1989-09-12
PT83119B (pt) 1989-03-30

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