DK1040202T3 - DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometri - Google Patents
DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometriInfo
- Publication number
- DK1040202T3 DK1040202T3 DK98955222T DK98955222T DK1040202T3 DK 1040202 T3 DK1040202 T3 DK 1040202T3 DK 98955222 T DK98955222 T DK 98955222T DK 98955222 T DK98955222 T DK 98955222T DK 1040202 T3 DK1040202 T3 DK 1040202T3
- Authority
- DK
- Denmark
- Prior art keywords
- flow cytometry
- dna
- identity determination
- dna polymorphism
- immobilized
- Prior art date
Links
- 238000000684 flow cytometry Methods 0.000 title abstract 3
- 108020004414 DNA Proteins 0.000 abstract 3
- 102000053602 DNA Human genes 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 239000005546 dideoxynucleotide Substances 0.000 abstract 2
- 102000012410 DNA Ligases Human genes 0.000 abstract 1
- 108010061982 DNA Ligases Proteins 0.000 abstract 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6862—Ligase chain reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6368597P | 1997-10-28 | 1997-10-28 | |
PCT/US1998/023143 WO1999022030A1 (en) | 1997-10-28 | 1998-10-28 | Dna polymorphism identity determination using flow cytometry |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1040202T3 true DK1040202T3 (da) | 2009-04-14 |
Family
ID=22050818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98955222T DK1040202T3 (da) | 1997-10-28 | 1998-10-28 | DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometri |
Country Status (13)
Country | Link |
---|---|
US (2) | US6287766B1 (da) |
EP (3) | EP1040202B9 (da) |
JP (3) | JP2003502005A (da) |
AT (1) | ATE419382T1 (da) |
AU (2) | AU1207799A (da) |
CA (2) | CA2308599C (da) |
DE (1) | DE69840416D1 (da) |
DK (1) | DK1040202T3 (da) |
ES (1) | ES2320604T3 (da) |
IL (2) | IL135851A (da) |
IS (2) | IS5455A (da) |
PT (1) | PT1040202E (da) |
WO (2) | WO1999022029A1 (da) |
Families Citing this family (68)
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US6913935B1 (en) * | 1997-12-04 | 2005-07-05 | Amersham Biosciences Uk Limited | Multiple assay method |
WO2000056925A2 (en) * | 1999-03-19 | 2000-09-28 | Aclara Biosciences, Inc. | Methods for single nucleotide polymorphism detection |
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DE19958980A1 (de) * | 1999-11-18 | 2001-09-27 | Wolfgang Goehde | Verfahren zur Bestimmung von PCR-Produkten, sowie ein PCR-Detektions-Kit und eine Vorrichtung für ein solches Verfahren |
AU2001238068A1 (en) * | 2000-02-07 | 2001-08-14 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
US6365355B1 (en) | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
US6340566B1 (en) * | 2000-03-28 | 2002-01-22 | The Regents Of The University Of California | Detection and quantitation of single nucleotide polymorphisms, DNA sequence variations, DNA mutations, DNA damage and DNA mismatches |
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NZ502323A (en) * | 1996-06-04 | 2001-09-28 | Univ Utah Res Found | Monitoring a fluorescence energy transfer pair during hybridization of first probe labelled with fluorescein to second probe labelled with Cy5 or Cy5.5 |
AU8162498A (en) * | 1997-06-25 | 1999-01-04 | Orchid Biosciences, Inc. | Methods for the detection of multiple single nucleotide polymorphisms in a single reaction |
US6287766B1 (en) * | 1997-10-28 | 2001-09-11 | The Regents Of The University Of California | DNA polymorphism identity determination using flow cytometry |
EP1090138A4 (en) | 1998-06-24 | 2003-01-02 | Glaxo Group Ltd | DETECTION METHOD FOR NUCLEOTIDES |
-
1998
- 1998-10-28 US US09/182,869 patent/US6287766B1/en not_active Expired - Lifetime
- 1998-10-28 EP EP98955222A patent/EP1040202B9/en not_active Expired - Lifetime
- 1998-10-28 CA CA2308599A patent/CA2308599C/en not_active Expired - Fee Related
- 1998-10-28 IL IL13585198A patent/IL135851A/en not_active IP Right Cessation
- 1998-10-28 DE DE69840416T patent/DE69840416D1/de not_active Expired - Lifetime
- 1998-10-28 AU AU12077/99A patent/AU1207799A/en not_active Abandoned
- 1998-10-28 WO PCT/US1998/023142 patent/WO1999022029A1/en not_active Application Discontinuation
- 1998-10-28 ES ES98955222T patent/ES2320604T3/es not_active Expired - Lifetime
- 1998-10-28 EP EP98955221A patent/EP1032701A1/en not_active Withdrawn
- 1998-10-28 JP JP2000518118A patent/JP2003502005A/ja active Pending
- 1998-10-28 DK DK98955222T patent/DK1040202T3/da active
- 1998-10-28 CA CA002306907A patent/CA2306907A1/en not_active Abandoned
- 1998-10-28 EP EP08104631A patent/EP2034031A1/en not_active Withdrawn
- 1998-10-28 JP JP2000518119A patent/JP4502502B2/ja not_active Expired - Fee Related
- 1998-10-28 PT PT98955222T patent/PT1040202E/pt unknown
- 1998-10-28 AT AT98955222T patent/ATE419382T1/de active
- 1998-10-28 AU AU12078/99A patent/AU754849B2/en not_active Ceased
- 1998-10-28 IL IL13585298A patent/IL135852A0/xx unknown
- 1998-10-28 WO PCT/US1998/023143 patent/WO1999022030A1/en active IP Right Grant
-
2000
- 2000-04-14 IS IS5455A patent/IS5455A/is unknown
- 2000-04-14 IS IS5454A patent/IS2699B/is unknown
-
2001
- 2001-09-11 US US09/953,534 patent/US20020015962A1/en not_active Abandoned
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2009
- 2009-12-22 JP JP2009291170A patent/JP2010088454A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IS5455A (is) | 2000-04-14 |
ES2320604T3 (es) | 2009-05-25 |
JP4502502B2 (ja) | 2010-07-14 |
EP1040202A1 (en) | 2000-10-04 |
JP2001520895A (ja) | 2001-11-06 |
JP2010088454A (ja) | 2010-04-22 |
IS5454A (is) | 2000-04-14 |
AU1207799A (en) | 1999-05-17 |
CA2306907A1 (en) | 1999-05-06 |
EP2034031A1 (en) | 2009-03-11 |
DE69840416D1 (de) | 2009-02-12 |
ATE419382T1 (de) | 2009-01-15 |
IL135851A (en) | 2004-03-28 |
IS2699B (is) | 2010-11-15 |
EP1040202B9 (en) | 2009-09-23 |
CA2308599A1 (en) | 1999-05-06 |
US20020015962A1 (en) | 2002-02-07 |
WO1999022029A1 (en) | 1999-05-06 |
AU754849B2 (en) | 2002-11-28 |
EP1040202B1 (en) | 2008-12-31 |
EP1032701A1 (en) | 2000-09-06 |
WO1999022030A1 (en) | 1999-05-06 |
EP1040202A4 (en) | 2004-08-18 |
AU1207899A (en) | 1999-05-17 |
PT1040202E (pt) | 2009-03-26 |
IL135852A0 (en) | 2001-05-20 |
US6287766B1 (en) | 2001-09-11 |
CA2308599C (en) | 2012-05-22 |
JP2003502005A (ja) | 2003-01-21 |
IL135851A0 (en) | 2001-05-20 |
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