[go: up one dir, main page]

DK1027343T3 - Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner - Google Patents

Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner

Info

Publication number
DK1027343T3
DK1027343T3 DK98948584T DK98948584T DK1027343T3 DK 1027343 T3 DK1027343 T3 DK 1027343T3 DK 98948584 T DK98948584 T DK 98948584T DK 98948584 T DK98948584 T DK 98948584T DK 1027343 T3 DK1027343 T3 DK 1027343T3
Authority
DK
Denmark
Prior art keywords
preparation
butyrolactones
hydroxy
substituted gamma
methyl ester
Prior art date
Application number
DK98948584T
Other languages
Danish (da)
English (en)
Inventor
Rawle I Hollingsworth
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25505755&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1027343(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Michigan State filed Critical Univ Michigan State
Application granted granted Critical
Publication of DK1027343T3 publication Critical patent/DK1027343T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)
DK98948584T 1997-10-31 1998-09-29 Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner DK1027343T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/962,365 US5808107A (en) 1997-10-31 1997-10-31 Process for the preparation of hydroxy substituted gamma butyrolactones
PCT/US1998/020448 WO1999023086A1 (en) 1997-10-31 1998-09-29 Process for the preparation of hydroxy substituted gamma butyrolactones

Publications (1)

Publication Number Publication Date
DK1027343T3 true DK1027343T3 (da) 2003-03-31

Family

ID=25505755

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98948584T DK1027343T3 (da) 1997-10-31 1998-09-29 Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner

Country Status (11)

Country Link
US (2) US5808107A (de)
EP (1) EP1027343B2 (de)
JP (1) JP3527706B2 (de)
KR (1) KR100369857B1 (de)
AT (1) ATE229013T1 (de)
CA (1) CA2304809C (de)
DE (1) DE69809962T3 (de)
DK (1) DK1027343T3 (de)
ES (1) ES2188017T5 (de)
PT (1) PT1027343E (de)
WO (1) WO1999023086A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618099D0 (en) 1996-08-30 1996-10-09 Zeneca Ltd Process
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
KR100622963B1 (ko) * 1998-03-03 2006-09-12 다이소 가부시키가이샤 1,2,4-부탄트리올의 제조 방법
US6949684B2 (en) 1998-03-03 2005-09-27 Daiso Co., Ltd. Process for preparing 1,2,4-butanetriol
US6084131A (en) * 1998-06-01 2000-07-04 Board Of Trustees Operating Michigan State University Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof
US6040464A (en) * 1998-06-01 2000-03-21 Board Of Trustees Operating Michigan State University Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof
KR100310935B1 (ko) 1998-07-24 2001-10-18 박영구 광학적으로 순수한 (ｓ)-3-히드록시-감마-부티로락톤의 연속적 제조방법
US6713290B2 (en) * 1998-07-24 2004-03-30 Samsung Fine Chemicals Co., Ltd. Process for preparing optically pure (S)-3-hydroxy-γ-butyrolactone
US6423850B1 (en) * 1999-06-18 2002-07-23 E.I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
KR100645665B1 (ko) 2000-07-27 2006-11-13 에스케이 주식회사 (ｓ)-베타-하이드록시-감마-부티로락톤의 연속 제조방법
US6288239B1 (en) 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
US6288238B1 (en) 2000-09-19 2001-09-11 Board Of Trustees Operating Michigan State University Process for the preparation of 5-hydroxymethyl 2-oxazolidinone and novel intermediate
JP4824874B2 (ja) * 2001-07-19 2011-11-30 高砂香料工業株式会社 光学活性γ−ブチロラクトンの製造方法
EP1398312A1 (de) * 2002-09-13 2004-03-17 Hong-Sun Uh Beta-substituierte gamma-Butyrolactone und Verfahren ihrer Herstellung
JP2005539078A (ja) * 2002-09-18 2005-12-22 エス ケー コーポレイション 光学的に純粋な（Ｓ）−β−ヒドロキシ−γ−ブチロラクトンの連続製造方法
WO2005068642A2 (en) 2003-10-01 2005-07-28 Board Of Trustees Operating Michigan State University Bacterial synthesis of 1,2,4-butanetriol enantiomers
CN100335457C (zh) * 2005-09-08 2007-09-05 上海交通大学 3－位手性羟基被保护的3，4－二羟基丁酸酯及其制备方法
WO2007100227A1 (en) * 2006-03-02 2007-09-07 Lg Chem, Ltd. Method for preparing (s)-3-hydroxy-gamma-butyrolactone using hydrolase
US20110165641A1 (en) * 2006-03-31 2011-07-07 The Board Of Trustees Of Michigan State University Synthesis of 1,2,4-Butanetriol Enantiomers from Carbohydrates
WO2008091288A2 (en) * 2006-07-19 2008-07-31 Board Of Trustees Of Michigan State University Microbial synthesis of d-1,2,4-butanetriol
CN100441573C (zh) * 2006-07-20 2008-12-10 厦门大学 一种合成s-(3)-羟基四氢呋喃的方法
CA2791425A1 (en) * 2009-03-06 2010-09-10 Massachusetts Institute Of Technology Microbial production of 3-hydroxyacids from glucose and glycolate
US8669379B2 (en) 2011-02-25 2014-03-11 Massachusetts Institute Of Technology Microbial production of 3,4-dihydroxybutyrate (3,4-DHBA), 2,3-dihydroxybutyrate (2,3-DHBA) and 3-hydroxybutyrolactone (3-HBL)
WO2017159669A1 (ja) * 2016-03-15 2017-09-21 塩野義製薬株式会社 フェノキシエタノール誘導体の製造方法
EP3740189A1 (de) 2017-12-18 2020-11-25 Tris Pharma, Inc. Arzneimittelpulverzusammensetzung mit modifizierter freisetzung mit gastro-retentiven raft-bildenden systemen mit triggerimpuls-arzneimittelfreisetzung
WO2019126214A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Pharmaceutical composition comprising ghb gastro-retentive raft forming systems having trigger pulse drug release
CA3085941A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
FR3088324B1 (fr) * 2018-11-08 2020-10-09 Inst Des Sciences Et Industries Du Vivant Et De Lenvironnement Agroparistech Procede biocatalytique de production de 2h-hbo a partir de lgo utilisant une cyclohexanone monooxygenase
CN112939901B (zh) * 2021-02-09 2023-05-09 中国科学院福建物质结构研究所 一种α-羟基-γ-丁内酯的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3024250A (en) * 1962-03-06 Certificate of correction
US2683721A (en) * 1952-01-17 1954-07-13 Hermann I Schlesinger Method of reducing and hydrogenating chemical compounds by reacting with alkali metal borohydrides
US3997569A (en) * 1972-11-08 1976-12-14 Texaco Inc. Method for preparing a lactone reaction product
US3868370A (en) * 1973-02-09 1975-02-25 Gen Electric Process for making 4-butyrolactone
US4083809A (en) * 1976-08-20 1978-04-11 Gaf Corporation Hydrogenation catalyst and method of producing same
GB1587198A (en) * 1976-11-23 1981-04-01 Ucb Sa Process for the production of butane-1,4 diol and tetrahydrofuran
US4772729A (en) * 1987-01-23 1988-09-20 E. I. Du Pont De Nemours And Company Hydrogenation of citric acid and substituted citric acids to 3-substituted tetrahydrofuran, 3- and 4-substituted butyrolactones and mixtures thereof
EP0304696B1 (de) * 1987-08-08 1992-04-29 BASF Aktiengesellschaft Verfahren zur Herstellung von 1,4-Butandiol und/oder Tetrahydrofuran
CA1307796C (en) * 1988-04-27 1992-09-22 Kenji Inoue Method for preparing optically active 3,4-dihydroxy butyric acid derivatives
US5087751A (en) * 1988-04-27 1992-02-11 Kanegafuchi Kagaku Kogyo K.K. Method of preparing optically active 3,4-dihydroxy butyric acid derivatives
CA2049536C (en) * 1991-05-13 1999-07-06 Rawle I. Hollingsworth Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof
DE69225560T2 (de) * 1991-11-18 1998-11-12 Sagami Chem Res Verfahren zur Herstellung von Lactonen
GB9618099D0 (en) † 1996-08-30 1996-10-09 Zeneca Ltd Process

Also Published As

Publication number Publication date
CA2304809C (en) 2006-08-01
CA2304809A1 (en) 1999-05-14
ES2188017T5 (es) 2006-07-16
USRE38324E1 (en) 2003-11-18
EP1027343B1 (de) 2002-12-04
PT1027343E (pt) 2003-04-30
DE69809962D1 (de) 2003-01-16
US5808107A (en) 1998-09-15
EP1027343A1 (de) 2000-08-16
KR20010031475A (ko) 2001-04-16
EP1027343A4 (de) 2001-08-22
KR100369857B1 (ko) 2003-02-05
DE69809962T2 (de) 2003-04-24
DE69809962T3 (de) 2006-12-14
EP1027343B2 (de) 2006-01-11
ATE229013T1 (de) 2002-12-15
JP3527706B2 (ja) 2004-05-17
WO1999023086A1 (en) 1999-05-14
ES2188017T3 (es) 2003-06-16
JP2001521931A (ja) 2001-11-13

Similar Documents

Publication Publication Date Title
DK1027343T3 (da) Fremgangsmåde til fremstilling af hydroxysubstituerede gamma-butyrolactoner
EA199800290A1 (ru) (метилсульфонил) фенил-2-(5н)-фураноны в качестве ингибиторов циклооксигеназы-2
MX9700564A (es) Derivados de benzoilo y sintesis de los mismos.
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
DE69620240D1 (de) Herstellung von levulinsäure aus kohlenhydrathaltigen materialien
KR970702868A (ko) 폴리피롤카복스아미도 나프탈렌 유도체에 연결함으로써 생유용성을 증진시킨 생물학적 활성 화합물(Increased bioavailability of biologically active compounds by linking to polypyrrole-carboxamidonaphthalene derivatives)
DE69610422D1 (de) Assymetrische synthese von (-) 6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2h-3,1-benzoxazin-2-on
PT841929E (pt) Quinolonas e sua utilizacao terapeutica
CA2234642A1 (en) 3,4-diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors
FR2392964A1 (fr) Nouveaux derives de cyclopropane, leur procede de preparation et leur application comme insecticides
PT788360E (pt) Compostos de acido e ester boronico, sinteses e utilizacoes.
EA200100774A1 (ru) Гетероциклические производные с функциональными группами (варианты), фармацевтическая композиция и комбинация, способ модулирования активности рецептора хемокина (варианты), способ профилактики инфицирования вич и лечения инфекции вич, замедления проявления спид и лечения спид, способ лечения воспалительных процессов
FR2742749B1 (fr) Nouvelles phenylimidazolidines comportant notamment un radical nitrooxy ou carbonyloxy, procede et intermediaires de preparation, application comme medicaments, nouvelles utilisations et compositions pharmaceutiques
ATE272398T1 (de) Verwendung von ep4 rezeptorliganden zur behandlung von neuropathischen schmerz
GEP19971017B (en) Process of preparation of benzocycloalkenyldihydroxyalkanoic acids derivatives
FR2772759B1 (fr) Nouveaux derives de l'acide 2,2-dimethyl 3-(2-fluorovinyl) cyclopropane carboxylique, leur procede de preparation et leur application comme pesticides
NO974155L (no) Ny fremgangsmåte for fremstilling av 2,3-dihydrobenzofuranolderivater
ATE127465T1 (de) Isoindolinon-derivat, seine herstellung und dieses enthaltende pharmazeutische zusammen setzungen.
YU49316B (sh) Novi intermedijari, njihova primena u sintezi n,n'-premoštenih bisindolilmaleimida i farmaceutske formulacije
DZ2423A1 (fr) Procédé pour la préparation d'acides 4-phényl-4-cyanocyclohexanoiques substitués.
DK1001929T3 (da) Fremgangsmåde til fremstilling af 3-cyano-2,4-dihalogen-5-flour-benzoesyrer
BG98888A (en) Method for the preparation of 3-acylestratrienes and acylbezenes
DE69928123D1 (de) Ester von 3-(3,4-dihalogenophenyl)-2,6-dioxopiperidine-3-propionsäure als zwischenprodukte
BR9508302A (pt) Derivados de benzoila e sua sintese
ATE252566T1 (de) Herstellung von 2-(2-arylmorpholin-2- yl)ethanolderivaten und zwischenprodukte