PT841929E - Quinolonas e sua utilizacao terapeutica - Google Patents

Quinolonas e sua utilizacao terapeutica

Info

Publication number: PT841929E
Authority: PT; Portugal
Prior art keywords: quinolones; compounds; therapeutic utilization; mixtures; formula
Prior art date: 1995-08-02

Application number

PT96925905T

Other languages

English (en)

Inventor

Hazel Joan Dyke

Hannah Jayne Kendall

John Gary Montana

David Thomas Manallack

Andrew Douglas Baxter

Steven Colin Beasley

Alan Findlay Haughan

Karen Ann Runcie

George Martin Buckley

Robert James Maxey

Original Assignee

Darwin Discovery Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-02

Filing date

1996-08-02

Publication date

2003-09-30

1995-08-02 Priority claimed from GBGB9515811.9A external-priority patent/GB9515811D0/en

1995-12-22 Priority claimed from GBGB9526377.8A external-priority patent/GB9526377D0/en

1996-03-20 Priority claimed from GBGB9605868.0A external-priority patent/GB9605868D0/en

1996-06-07 Priority claimed from GBGB9611898.9A external-priority patent/GB9611898D0/en

1996-08-02 Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd

2003-09-30 Publication of PT841929E publication Critical patent/PT841929E/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Neurology (AREA)
Hematology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Virology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)

PT96925905T 1995-08-02 1996-08-02 Quinolonas e sua utilizacao terapeutica PT841929E (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9515811.9A GB9515811D0 (en)	1995-08-02	1995-08-02	Novel compounds
GBGB9526377.8A GB9526377D0 (en)	1995-12-22	1995-12-22	Novel compounds
GBGB9605868.0A GB9605868D0 (en)	1996-03-20	1996-03-20	Novel compounds
GBGB9611898.9A GB9611898D0 (en)	1996-06-07	1996-06-07	Quinolones and their therapeutic use

Publications (1)

Publication Number	Publication Date
PT841929E true PT841929E (pt)	2003-09-30

Family

ID=27451319

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96925905T PT841929E (pt)	1995-08-02	1996-08-02	Quinolonas e sua utilizacao terapeutica

Country Status (12)

Country	Link
US (1)	US5891878A (pt)
EP (1)	EP0841929B1 (pt)
JP (1)	JPH11513021A (pt)
AT (1)	ATE239477T1 (pt)
AU (1)	AU696390B2 (pt)
CA (1)	CA2225552A1 (pt)
DE (1)	DE69628019T2 (pt)
DK (1)	DK0841929T3 (pt)
ES (1)	ES2193252T3 (pt)
MX (1)	MX9800922A (pt)
PT (1)	PT841929E (pt)
WO (1)	WO1997004779A1 (pt)

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IT1296985B1 (it)	1997-12-19	1999-08-03	Zambon Spa	Derivati benzazinici inibitori della fosfodiesterasi 4
CN1128790C (zh) *	1997-12-22	2003-11-26	法玛西雅厄普约翰美国公司	用作抗病毒剂的4－羟基喹啉－3－甲酰胺和酰肼化合物
IT1302677B1 (it) *	1998-10-15	2000-09-29	Zambon Spa	Derivati benzazinici inibitori della fosfodiesterasi 4
US6248739B1 (en) *	1999-01-08	2001-06-19	Pharmacia & Upjohn Company	Quinolinecarboxamides as antiviral agents
US6248736B1 (en) *	1999-01-08	2001-06-19	Pharmacia & Upjohn Company	4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
HU229439B1 (hu)	1999-08-21	2013-12-30	Takeda Gmbh	Roflumilast és salmeterol szinergetikus kombinációja
US6436971B2 (en) *	2000-02-09	2002-08-20	Smithkline Beecham Corporation	Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection
US6458788B1 (en)	2000-03-21	2002-10-01	Pharmacia & Upjohn Company	4-hydroxycinnoline-3-carboxyamides as antiviral agents
JP2003528087A (ja)	2000-03-21	2003-09-24	ファルマシア・アンド・アップジョン・カンパニー	抗ウイルス剤としての４−オキソ−１，４−ジヒドロ−３−シンノリンカルボキサミド
AU2001243241A1 (en)	2000-03-21	2001-10-03	Pharmacia And Upjohn Company Llc	4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents
US6451811B2 (en)	2000-03-21	2002-09-17	Pharmacia & Upjohn Company	4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxamides as antiviral agents
PE20011349A1 (es) *	2000-06-16	2002-01-19	Upjohn Co	1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6730682B2 (en) *	2000-07-12	2004-05-04	Pharmacia & Upjohn Company	Heterocycle carboxamides as antiviral agents
US6562822B2 (en)	2000-07-12	2003-05-13	Pharmacia & Upjohn Company	Heterocyle carboxamides as antiviral agents
US6559145B2 (en)	2000-07-12	2003-05-06	Pharmacia & Upjohn Company	Heterocycle carboxamides as antiviral agents
US20100074949A1 (en)	2008-08-13	2010-03-25	William Rowe	Pharmaceutical composition and administration thereof
PE20020856A1 (es) *	2001-02-13	2002-11-11	Aventis Pharma Gmbh	1,2,3,4-tetrahidronaftil aminas aciladas
TWI243164B (en)	2001-02-13	2005-11-11	Aventis Pharma Gmbh	Acylated indanyl amines and their use as pharmaceuticals
JP2004520424A (ja)	2001-03-01	2004-07-08	ファルマシア・アンド・アップジョン・カンパニー	抗ウイルス剤としての置換型キノリンカルボキサミド
CN1578781A (zh)	2001-09-26	2005-02-09	拜尔药品公司	用作抗糖尿病药物的1,8－萘啶衍生物
US20070213310A1 (en) *	2002-04-01	2007-09-13	Laszlo Prokai	Prodrugs for Use as Ophthalmic Agents
ATE353907T1 (de) *	2002-04-01	2007-03-15	Univ Florida	Steroidische chinole als antioxidantien-vorstufen
US7186707B2 (en)	2002-04-01	2007-03-06	University Of Florida	Prodrugs for use as ophthalmic agents
US7300926B2 (en) *	2002-04-01	2007-11-27	University Of Florida Research Foundation, Inc.	Steroidal quinols and their use for estrogen replacement therapy
EP1569648A4 (en) *	2002-12-09	2006-10-04	Univ Florida	PRODRUGS FOR OPHTHALMIKA
CA2530352A1 (en)	2003-07-24	2005-02-03	Astellas Pharma Inc.	Quinolone derivative or salt thereof
US7470706B2 (en) *	2004-01-31	2008-12-30	Sanofi-Aventis Deutschland Gmbh	Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
DE102004004971B3 (de) *	2004-01-31	2005-09-15	Aventis Pharma Deutschland Gmbh	Cycloalkyl substituierte 7-Amino-4-chinolon-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arnzeimittel
EP1736465A4 (en)	2004-03-31	2009-06-17	Ajinomoto Kk	ANILINE DERIVATIVES
US8354427B2 (en)	2004-06-24	2013-01-15	Vertex Pharmaceutical Incorporated	Modulators of ATP-binding cassette transporters
RU2556984C2 (ru) *	2004-06-24	2015-07-20	Вертекс Фармасьютикалз Инкорпорейтед	Модуляторы транспортеров атф-связывающей кассеты
PT2489659T (pt) *	2004-06-24	2018-03-07	Vertex Pharma	Moduladores de transportadores de cassete de ligação a atp
EP3216787B1 (en) *	2004-06-24	2020-02-19	Vertex Pharmaceuticals Incorporated	Intermediates for the preparation of modulators of atp-binding cassette transporters
DE102004035203A1 (de)	2004-07-21	2006-02-16	Bayer Healthcare Ag	Substituierte Chinolone
DE102005030524A1 (de)	2005-06-30	2007-01-18	Aicuris Gmbh & Co. Kg	Substituierte Chinolone II
CN101374849A (zh) *	2005-12-24	2009-02-25	沃泰克斯药物股份有限公司	作为abc转运蛋白调控剂的喹啉-4-酮衍生物
CA2635214A1 (en) *	2005-12-27	2007-07-05	Vertex Pharmaceuticals Incorporated	Compounds useful in cftr assays and methods therewith
SI3219705T1 (sl)	2005-12-28	2020-08-31	Vertex Pharmaceuticals Incorporated	Farmacevtski sestavki amorfne oblike N-(2,4-bis(1,1-dimetiletil)-5- hidroksifenil)-1,4-dihidro-4-oksokinolin-3-karboksamid
DE102006005861A1 (de)	2006-02-09	2007-08-23	Aicuris Gmbh & Co. Kg	Substituierte Chinolone III
DK2383271T3 (da) *	2006-03-13	2013-10-07	Kyorin Seiyaku Kk	Aminoquinoloner som GSK-3-inhibitorer
NZ592685A (en)	2008-10-23	2013-04-26	Vertex Pharma	Modulators of cystic fibrosis transmembrane conductance regulator
SG193156A1 (en)	2009-03-20	2013-09-30	Vertex Pharma	Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en)	2010-12-10	2014-08-12	Vertex Pharmaceuticals Incorporated	Modulators of ATP-Binding Cassette transporters
CN109966264A (zh)	2012-02-27	2019-07-05	沃泰克斯药物股份有限公司	药物组合物及其施用
GB201409044D0 (en)	2014-05-21	2014-07-02	Ucl Business Plc	New compounds
ES2702288T3 (es)	2014-10-07	2019-02-28	Vertex Pharma	Co-cristales de moduladores de regulador de conductancia transmembrana de la fibrosis quística
CN107998131B (zh) *	2017-12-27	2019-09-24	湖北工业大学	芳香酯类化合物用于制备抗adv-7病毒药物
CN111646941A (zh) *	2020-07-17	2020-09-11	天津科技大学	一种磺酰胺类衍生物及其制备方法和应用

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US3524858A (en) *	1967-05-18	1970-08-18	Warner Lambert Pharmaceutical	1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid
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1996
- 1996-08-02 US US08/691,338 patent/US5891878A/en not_active Expired - Fee Related
- 1996-08-02 MX MX9800922A patent/MX9800922A/es not_active IP Right Cessation
- 1996-08-02 DE DE69628019T patent/DE69628019T2/de not_active Expired - Fee Related
- 1996-08-02 ES ES96925905T patent/ES2193252T3/es not_active Expired - Lifetime
- 1996-08-02 EP EP96925905A patent/EP0841929B1/en not_active Expired - Lifetime
- 1996-08-02 DK DK96925905T patent/DK0841929T3/da active
- 1996-08-02 WO PCT/GB1996/001862 patent/WO1997004779A1/en active IP Right Grant
- 1996-08-02 PT PT96925905T patent/PT841929E/pt unknown
- 1996-08-02 JP JP9507373A patent/JPH11513021A/ja not_active Ceased
- 1996-08-02 AT AT96925905T patent/ATE239477T1/de not_active IP Right Cessation
- 1996-08-02 CA CA002225552A patent/CA2225552A1/en not_active Abandoned
- 1996-08-02 AU AU66263/96A patent/AU696390B2/en not_active Ceased

Also Published As

Publication number	Publication date
ATE239477T1 (de)	2003-05-15
US5891878A (en)	1999-04-06
JPH11513021A (ja)	1999-11-09
DE69628019T2 (de)	2004-01-22
AU696390B2 (en)	1998-09-10
MX9800922A (es)	1998-05-31
EP0841929B1 (en)	2003-05-07
CA2225552A1 (en)	1997-02-13
AU6626396A (en)	1997-02-26
WO1997004779A1 (en)	1997-02-13
DK0841929T3 (da)	2003-09-01
EP0841929A1 (en)	1998-05-20
DE69628019D1 (de)	2003-06-12
ES2193252T3 (es)	2003-11-01

Publication	Publication Date	Title
PT841929E (pt)	2003-09-30	Quinolonas e sua utilizacao terapeutica
DK0636025T3 (da)	2001-10-29	Forbindelser, der er egnede til behandling af allergiske og inflammatoriske sygdomme
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