DK0868530T3 - Kaskade-nucleinsyreamplificeringsreaktion - Google Patents
Kaskade-nucleinsyreamplificeringsreaktionInfo
- Publication number
- DK0868530T3 DK0868530T3 DK96939821T DK96939821T DK0868530T3 DK 0868530 T3 DK0868530 T3 DK 0868530T3 DK 96939821 T DK96939821 T DK 96939821T DK 96939821 T DK96939821 T DK 96939821T DK 0868530 T3 DK0868530 T3 DK 0868530T3
- Authority
- DK
- Denmark
- Prior art keywords
- oligonucleotide
- circular
- dna
- necessary
- dna sequence
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 abstract 5
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108020004638 Circular DNA Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108060002716 Exonuclease Proteins 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 102000013165 exonuclease Human genes 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- -1 nucleoside triphosphates Chemical class 0.000 abstract 1
- 239000001226 triphosphate Substances 0.000 abstract 1
- 235000011178 triphosphate Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Ceramic Products (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK137995 | 1995-12-05 | ||
| PCT/DK1996/000513 WO1997020948A1 (en) | 1995-12-05 | 1996-12-05 | A cascade nucleic acid amplification reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0868530T3 true DK0868530T3 (da) | 2003-07-21 |
Family
ID=8104224
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03000499T DK1300466T3 (da) | 1995-12-05 | 1996-12-05 | En kaskade nukleinsyre amplifikationsreaktion |
| DK96939821T DK0868530T3 (da) | 1995-12-05 | 1996-12-05 | Kaskade-nucleinsyreamplificeringsreaktion |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03000499T DK1300466T3 (da) | 1995-12-05 | 1996-12-05 | En kaskade nukleinsyre amplifikationsreaktion |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6610481B2 (de) |
| EP (2) | EP1300466B1 (de) |
| AT (2) | ATE238434T1 (de) |
| AU (1) | AU704750B2 (de) |
| CA (1) | CA2239287C (de) |
| DE (2) | DE69636080T2 (de) |
| DK (2) | DK1300466T3 (de) |
| ES (1) | ES2262902T3 (de) |
| WO (1) | WO1997020948A1 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077668A (en) * | 1993-04-15 | 2000-06-20 | University Of Rochester | Highly sensitive multimeric nucleic acid probes |
| US7135312B2 (en) | 1993-04-15 | 2006-11-14 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| WO1997019193A2 (en) * | 1995-11-21 | 1997-05-29 | Yale University | Unimolecular segment amplification and detection |
| US6255082B1 (en) | 1998-09-15 | 2001-07-03 | Yale University | Artificial long terminal repeat vectors |
| EP1114184A2 (de) * | 1998-09-15 | 2001-07-11 | Yale University | Klonierung mittels "rolling circle" amplifizierung |
| WO2000065049A1 (fr) * | 1999-04-27 | 2000-11-02 | Genox Research, Inc. | Gene 513 associe a la pollinose |
| US6368801B1 (en) | 2000-04-12 | 2002-04-09 | Molecular Staging, Inc. | Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase |
| AU2001271722B2 (en) | 2000-06-30 | 2006-04-13 | Qiagen, Gmbh | Signal amplification with lollipop probes |
| GB0025144D0 (en) * | 2000-10-13 | 2000-11-29 | Medical Res Council | Concatenated nucleic acid sequences |
| US6573051B2 (en) | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
| WO2003002761A1 (en) * | 2001-06-29 | 2003-01-09 | Novozymes A/S | Method of multimerization and site-directed mutagenesis |
| GB2378245A (en) | 2001-08-03 | 2003-02-05 | Mats Nilsson | Nucleic acid amplification method |
| GB2382137A (en) | 2001-11-20 | 2003-05-21 | Mats Gullberg | Nucleic acid enrichment |
| US7553619B2 (en) | 2002-02-08 | 2009-06-30 | Qiagen Gmbh | Detection method using dissociated rolling circle amplification |
| US8394944B2 (en) * | 2002-09-20 | 2013-03-12 | Siemens Healthcare Diagnostics Inc. | Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation |
| WO2004048594A2 (en) | 2002-11-21 | 2004-06-10 | Epicentre Technologies | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences |
| US9487823B2 (en) | 2002-12-20 | 2016-11-08 | Qiagen Gmbh | Nucleic acid amplification |
| US6977153B2 (en) | 2002-12-31 | 2005-12-20 | Qiagen Gmbh | Rolling circle amplification of RNA |
| KR20120075495A (ko) * | 2004-09-27 | 2012-07-06 | 후루카와 덴키 고교 가부시키가이샤 | 접속부재 |
| US20080305142A1 (en) * | 2004-12-11 | 2008-12-11 | Cytogenix, Inc. | Cell Free Biosynthesis of High-Quality Nucleic Acid and Uses Thereof |
| GB0504774D0 (en) * | 2005-03-08 | 2005-04-13 | Lingvitae As | Method |
| US7989166B2 (en) | 2005-04-12 | 2011-08-02 | In Situ Rcp A/S | Circle probes and their use in the identification of biomolecules |
| US8080393B2 (en) | 2005-04-12 | 2011-12-20 | Olink Ab | Methods for production of oligonucleotides |
| US20090264299A1 (en) * | 2006-02-24 | 2009-10-22 | Complete Genomics, Inc. | High throughput genome sequencing on DNA arrays |
| EP3492602A1 (de) | 2005-06-15 | 2019-06-05 | Complete Genomics, Inc. | Einzelne molekülarrays für genetische und chemische analyse |
| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| CA2624324A1 (en) | 2005-10-06 | 2007-04-19 | Lucigen Corporation | Thermostable viral polymerases and methods of use |
| US7960104B2 (en) * | 2005-10-07 | 2011-06-14 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| US20070168197A1 (en) * | 2006-01-18 | 2007-07-19 | Nokia Corporation | Audio coding |
| EP1994180A4 (de) | 2006-02-24 | 2009-11-25 | Callida Genomics Inc | Genomsequenzierung auf dna-arrays mit hohem durchsatz |
| GB0621361D0 (en) * | 2006-10-26 | 2006-12-06 | Fermentas Uab | Use of DNA polymerases |
| US7910354B2 (en) | 2006-10-27 | 2011-03-22 | Complete Genomics, Inc. | Efficient arrays of amplified polynucleotides |
| US20090111705A1 (en) | 2006-11-09 | 2009-04-30 | Complete Genomics, Inc. | Selection of dna adaptor orientation by hybrid capture |
| US20080221832A1 (en) * | 2006-11-09 | 2008-09-11 | Complete Genomics, Inc. | Methods for computing positional base probabilities using experminentals base value distributions |
| RU2414510C2 (ru) * | 2007-06-14 | 2011-03-20 | Институт биохимии и генетики Уфимского научного центра РАН | Способ амплификации специфичных фрагментов нуклеиновых кислот с помощью рекуррентной цепной реакции |
| US8415099B2 (en) * | 2007-11-05 | 2013-04-09 | Complete Genomics, Inc. | Efficient base determination in sequencing reactions |
| US7901890B2 (en) * | 2007-11-05 | 2011-03-08 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation |
| US7897344B2 (en) * | 2007-11-06 | 2011-03-01 | Complete Genomics, Inc. | Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs |
| US8518640B2 (en) * | 2007-10-29 | 2013-08-27 | Complete Genomics, Inc. | Nucleic acid sequencing and process |
| US8617811B2 (en) | 2008-01-28 | 2013-12-31 | Complete Genomics, Inc. | Methods and compositions for efficient base calling in sequencing reactions |
| WO2009073629A2 (en) | 2007-11-29 | 2009-06-11 | Complete Genomics, Inc. | Efficient shotgun sequencing methods |
| US8592150B2 (en) | 2007-12-05 | 2013-11-26 | Complete Genomics, Inc. | Methods and compositions for long fragment read sequencing |
| WO2009094583A1 (en) * | 2008-01-23 | 2009-07-30 | Complete Genomics, Inc. | Methods and compositions for preventing bias in amplification and sequencing reactions |
| US20090270273A1 (en) * | 2008-04-21 | 2009-10-29 | Complete Genomics, Inc. | Array structures for nucleic acid detection |
| US9524369B2 (en) | 2009-06-15 | 2016-12-20 | Complete Genomics, Inc. | Processing and analysis of complex nucleic acid sequence data |
| CN103649331A (zh) | 2011-02-15 | 2014-03-19 | 莱卡生物系统纽卡斯尔有限责任公司 | 用于mrna的定位的原位检测的方法 |
| US9556473B2 (en) | 2011-02-15 | 2017-01-31 | Leica Biosystems Newcastle Ltd | Methods for identifying nucleic acid sequences |
| US8778848B2 (en) | 2011-06-09 | 2014-07-15 | Illumina, Inc. | Patterned flow-cells useful for nucleic acid analysis |
| AU2012328662B2 (en) | 2011-10-28 | 2015-12-17 | Illumina, Inc. | Microarray fabrication system and method |
| US10174366B2 (en) | 2012-11-14 | 2019-01-08 | Olink Bioscience Ab | Localised RCA-based amplification method |
| EP2920320B1 (de) | 2012-11-14 | 2016-12-28 | Olink Bioscience AB | Rca-reportersonden und deren verwendung zur detektion von nukleinsäuremolekülen |
| GB201320145D0 (en) | 2013-11-14 | 2014-01-01 | Olink Ab | Localised RCA-based amplification method using a padlock-probe |
| SG10201809312QA (en) | 2014-05-16 | 2018-11-29 | Illumina Inc | Nucleic acid synthesis techniques |
| WO2016103234A1 (en) * | 2014-12-24 | 2016-06-30 | Abbott Japan Co., Ltd. | Detection method based on signal amplifier dna cascade reactions with target extension |
| GB201614023D0 (en) | 2016-08-16 | 2016-09-28 | Olink Bioscience Ab | Double-stranded circle probes |
| JP2020504600A (ja) | 2016-12-09 | 2020-02-13 | アルティヴュー， インク． | 標識化核酸イメージング剤を使用した多重イメージングのための改善された方法 |
| CN117187346A (zh) | 2017-03-31 | 2023-12-08 | 乌尔蒂维尤股份有限公司 | Dna-抗原交换和扩增 |
| CN116218893A (zh) * | 2023-03-24 | 2023-06-06 | 哈尔滨医科大学 | 一种通过体外扩增重组质粒在其编码基因上生成短片段串联重复序列的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| WO1992001813A1 (en) * | 1990-07-25 | 1992-02-06 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
| AU8997991A (en) | 1991-01-31 | 1992-08-06 | Becton Dickinson & Company | Exonuclease mediated strand displacement amplification |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| JP3080178B2 (ja) | 1991-02-18 | 2000-08-21 | 東洋紡績株式会社 | 核酸配列の増幅方法およびそのための試薬キット |
| JP3085409B2 (ja) * | 1991-03-29 | 2000-09-11 | 東洋紡績株式会社 | 標的核酸配列の検出方法およびそのための試薬キット |
| GB9117910D0 (en) * | 1991-08-20 | 1991-10-09 | Nat Res Dev | Oligonucleotides and their use in an assay |
| JPH07500734A (ja) * | 1991-10-31 | 1995-01-26 | ユニヴァーシティ オブ ピッツバーグ | オリゴヌクレオチドプローブのポリマーを用いる核酸配列の検出方法 |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| US6180338B1 (en) * | 1992-08-04 | 2001-01-30 | Beckman Coulter, Inc. | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
| EP0717782A1 (de) * | 1994-06-22 | 1996-06-26 | Mount Sinai School Of Medicine Of The City University Of New York | Ligation-abhängige amplifizierung zum nachweis von infektösen pathogenen und anormalen genen |
| US5876924A (en) | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| US5942391A (en) | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| WO1997019193A2 (en) * | 1995-11-21 | 1997-05-29 | Yale University | Unimolecular segment amplification and detection |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
-
1996
- 1996-12-05 WO PCT/DK1996/000513 patent/WO1997020948A1/en active IP Right Grant
- 1996-12-05 EP EP03000499A patent/EP1300466B1/de not_active Expired - Lifetime
- 1996-12-05 CA CA002239287A patent/CA2239287C/en not_active Expired - Fee Related
- 1996-12-05 DE DE69636080T patent/DE69636080T2/de not_active Expired - Lifetime
- 1996-12-05 EP EP96939821A patent/EP0868530B1/de not_active Expired - Lifetime
- 1996-12-05 AT AT96939821T patent/ATE238434T1/de not_active IP Right Cessation
- 1996-12-05 AU AU76917/96A patent/AU704750B2/en not_active Ceased
- 1996-12-05 ES ES03000499T patent/ES2262902T3/es not_active Expired - Lifetime
- 1996-12-05 AT AT03000499T patent/ATE324464T1/de not_active IP Right Cessation
- 1996-12-05 DK DK03000499T patent/DK1300466T3/da active
- 1996-12-05 DE DE69627698T patent/DE69627698T2/de not_active Expired - Lifetime
- 1996-12-05 DK DK96939821T patent/DK0868530T3/da active
-
1999
- 1999-12-17 US US09/465,589 patent/US6610481B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1300466A2 (de) | 2003-04-09 |
| AU704750B2 (en) | 1999-05-06 |
| ATE324464T1 (de) | 2006-05-15 |
| DK1300466T3 (da) | 2006-08-28 |
| EP0868530A1 (de) | 1998-10-07 |
| EP0868530B1 (de) | 2003-04-23 |
| WO1997020948A1 (en) | 1997-06-12 |
| US6610481B2 (en) | 2003-08-26 |
| CA2239287C (en) | 2008-02-26 |
| AU7691796A (en) | 1997-06-27 |
| EP1300466B1 (de) | 2006-04-26 |
| DE69636080T2 (de) | 2006-11-30 |
| US20020031764A1 (en) | 2002-03-14 |
| DE69627698T2 (de) | 2004-01-15 |
| EP1300466A3 (de) | 2004-01-02 |
| DE69627698D1 (de) | 2003-05-28 |
| DE69636080D1 (de) | 2006-06-01 |
| ATE238434T1 (de) | 2003-05-15 |
| ES2262902T3 (es) | 2006-12-01 |
| CA2239287A1 (en) | 1997-06-12 |
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