DK0864645T3 - Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet - Google Patents
Negativstrenget RNA-virusvektor med autonom replikeringsaktivitetInfo
- Publication number
- DK0864645T3 DK0864645T3 DK96935402T DK96935402T DK0864645T3 DK 0864645 T3 DK0864645 T3 DK 0864645T3 DK 96935402 T DK96935402 T DK 96935402T DK 96935402 T DK96935402 T DK 96935402T DK 0864645 T3 DK0864645 T3 DK 0864645T3
- Authority
- DK
- Denmark
- Prior art keywords
- stranded rna
- virus vector
- rna virus
- replication activity
- negative stranded
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18821—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18851—Methods of production or purification of viral material
- C12N2760/18852—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30831595 | 1995-10-31 | ||
PCT/JP1996/003068 WO1997016538A1 (fr) | 1995-10-31 | 1996-10-22 | Vecteur de virus d'arn a brin negatif possedant une activite de replication autonome |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0864645T3 true DK0864645T3 (da) | 2005-10-24 |
Family
ID=17979579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96935402T DK0864645T3 (da) | 1995-10-31 | 1996-10-22 | Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet |
Country Status (10)
Country | Link |
---|---|
US (2) | US6723532B2 (zh) |
EP (2) | EP1325960A3 (zh) |
KR (2) | KR100754091B1 (zh) |
CN (1) | CN1118569C (zh) |
AT (1) | ATE298789T1 (zh) |
AU (1) | AU7335196A (zh) |
DE (1) | DE69634904T2 (zh) |
DK (1) | DK0864645T3 (zh) |
HK (1) | HK1018287A1 (zh) |
WO (1) | WO1997016538A1 (zh) |
Families Citing this family (69)
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EP0863202B1 (en) * | 1995-11-01 | 2010-06-09 | Dnavec Research Inc. | Recombinant sendai virus |
CA2336472C (en) * | 1998-07-03 | 2010-08-31 | Dnavec Research Inc. | Negative-sense rna virus vector for nerve cell |
US7241617B2 (en) | 1998-07-03 | 2007-07-10 | Dnavec Research, Inc. | Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci |
US6828138B1 (en) | 1998-08-11 | 2004-12-07 | Dnavec Research Inc. | Recombinant sendai virus vector including a gene encoding a chemokine |
DK1106692T3 (da) * | 1998-08-11 | 2005-10-17 | Dnavec Research Inc | RNA-virusvektor med kontaktinfiltrationsevne |
US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
EP1013667B1 (en) * | 1998-11-09 | 2006-10-11 | Nippon Biologicals, Inc. | Process for preparation of cytokine using a sendai virus expression system |
US6490775B1 (en) * | 1999-04-23 | 2002-12-10 | Veri-Tek Inc. | Press operation verification system |
JP3602058B2 (ja) * | 1999-05-18 | 2004-12-15 | 株式会社ディナベック研究所 | エンベロープ遺伝子欠損パラミクソ科ウイルスベクター |
US7226786B2 (en) | 1999-05-18 | 2007-06-05 | Dnavec Research Inc. | Envelope gene-deficient Paramyxovirus vector |
US20030166252A1 (en) * | 1999-05-18 | 2003-09-04 | Kaio Kitazato | Paramyxovirus-derived RNP |
EP1211318B1 (en) * | 1999-09-06 | 2007-08-08 | DNAVEC Research, Inc. | Paramyxoviruses comprising a modified transcription start sequence |
JP4838962B2 (ja) * | 1999-11-02 | 2011-12-14 | 株式会社ディナベック研究所 | 気道上皮細胞への外因性遺伝子導入用組換えセンダイウイルスベクター |
US7314614B1 (en) | 1999-11-02 | 2008-01-01 | Dnavec Research, Inc. | Recombinant sendai virus vector for introducing exogenous genes to airway epithelia |
WO2001038537A1 (fr) | 1999-11-19 | 2001-05-31 | The Kitasato Institute | Procede d'elaboration d'un mutant du morbillivirus a fusion cellulaire |
KR100774796B1 (ko) * | 2000-01-19 | 2007-11-07 | 가부시키가이샤 디나벡크 겐큐쇼 | 파라믹소바이러스 벡터의 혈관으로의 유전자 도입용도 |
WO2001072340A1 (fr) * | 2000-03-30 | 2001-10-04 | Dnavec Research Inc. | Vaccin contre le virus du sida, contenant un vecteur du virus de sendai |
CA2322057A1 (en) | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
CN100531802C (zh) * | 2000-06-01 | 2009-08-26 | 株式会社载体研究所 | 含有血凝素活性膜蛋白质的假型逆转录病毒载体 |
EP1297852A4 (en) * | 2000-06-27 | 2004-12-29 | Dnavec Research Inc | VIRAL VECTOR FOR THE INTRODUCTION OF GENES IN KIDNEY CELLS (03.02.03) |
AU2001290273A1 (en) * | 2000-10-06 | 2002-04-22 | Dnavec Research Inc. | Paramyxovirus vector for transferring foreign gene into skeletal muscle |
JP2002142770A (ja) | 2000-11-08 | 2002-05-21 | Dnavec Research Inc | 循環系への遺伝子送達用パラミクソウイルスベクター |
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CN103540568A (zh) | 2002-04-26 | 2014-01-29 | 米迪缪尼有限公司 | 制备流感病毒的多质粒系统 |
US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
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KR101058294B1 (ko) * | 2002-04-30 | 2011-08-22 | 가부시키가이샤 디나벡크 겐큐쇼 | 프로테아제 의존성 트로피즘이 개변된 벡터 |
US20050191617A1 (en) * | 2002-06-03 | 2005-09-01 | Makoto Inoue | Pramyxovirusl vectors encoding antibody and utilization thereof |
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ATE469972T1 (de) | 2003-12-23 | 2010-06-15 | Medimmune Llc | Multiplasmid-system zur erzeugung des grippevirus |
CA2553377A1 (en) | 2004-01-13 | 2005-07-28 | Dnavec Research Inc. | Gene therapy for tumors using minus-strand rna viral vectors encoding immunostimaulatory cytokines |
CN1934257A (zh) * | 2004-01-22 | 2007-03-21 | 株式会社载体研究所 | 病毒载体的制备方法 |
KR101279677B1 (ko) | 2004-01-22 | 2013-06-27 | 가부시키가이샤 디나벡크 겐큐쇼 | 사이토메갈로바이러스 인핸서 및 닭 β액틴 프로모터를 포함하는 하이브리드 프로모터를 이용한 마이너스 가닥 RNA 바이러스 벡터의 제조방법 |
WO2005087269A1 (ja) * | 2004-03-16 | 2005-09-22 | Dnavec Research Inc. | 腫瘍増殖を抑制する方法 |
JPWO2005097988A1 (ja) * | 2004-03-23 | 2008-02-28 | 株式会社ディナベック研究所 | 組織の維持および/または修復に関連する骨髄関連細胞 |
CA2879182C (en) | 2004-05-25 | 2017-02-14 | Medimmune, Inc. | Influenza hemagglutinin and neuraminidase variants |
JPWO2006001120A1 (ja) * | 2004-06-24 | 2008-04-17 | 株式会社ディナベック研究所 | マイナス鎖rnaウイルスを含む抗癌剤 |
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US20110162093A1 (en) * | 2005-06-14 | 2011-06-30 | Yasuji Ueda | Methods for producing antibodies |
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CA2654033A1 (en) | 2006-05-31 | 2007-12-06 | Dnavec Corporation | Therapeutic agent for alzheimer's disease |
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CA2659267C (en) | 2006-08-09 | 2016-12-13 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
JPWO2008029790A1 (ja) | 2006-09-04 | 2010-01-21 | 協和発酵キリン株式会社 | 新規核酸 |
EP2123752A4 (en) | 2006-12-18 | 2010-08-11 | Kyowa Hakko Kirin Co Ltd | NOVEL NUCLEIC ACID |
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CA2685417A1 (en) | 2007-04-27 | 2008-11-13 | Kyushu University, National University Corporation | Viral vector for gene therapy |
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US5516720A (en) | 1994-02-14 | 1996-05-14 | United Microelectronics Corporation | Stress relaxation in dielectric before metallization |
ES2210273T5 (es) | 1994-07-18 | 2010-03-29 | Conzelmann, Karl-Klaus, Prof. Dr. | Virus con arn de cadena negativa no segmentado recombinante infeccioso. |
US5716821A (en) | 1994-09-30 | 1998-02-10 | Uab Research Foundation | Prevention and treatment of respiratory tract disease |
US5789229A (en) | 1994-09-30 | 1998-08-04 | Uab Research Foundation | Stranded RNA virus particles |
DK0780475T4 (da) | 1995-08-09 | 2006-10-23 | Schweiz Serum & Impfinst | Fremgangsmåde til fremstilling af infektiöse negativ-streng RNA-virus |
KR0179554B1 (ko) * | 1995-11-30 | 1999-04-15 | 김주용 | 반도체 소자의 소자분리절연막 형성방법 |
EP0906442A1 (en) | 1996-05-01 | 1999-04-07 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by The Secretary, Department of Health and Human Services | Generation of viral transfectants using recombinant dna-derived nucleocapsid proteins |
-
1996
- 1996-10-22 EP EP03002037A patent/EP1325960A3/en not_active Ceased
- 1996-10-22 DE DE69634904T patent/DE69634904T2/de not_active Expired - Lifetime
- 1996-10-22 DK DK96935402T patent/DK0864645T3/da active
- 1996-10-22 KR KR1020057010921A patent/KR100754091B1/ko not_active IP Right Cessation
- 1996-10-22 CN CN96199467A patent/CN1118569C/zh not_active Expired - Lifetime
- 1996-10-22 AT AT96935402T patent/ATE298789T1/de active
- 1996-10-22 EP EP96935402A patent/EP0864645B9/en not_active Expired - Lifetime
- 1996-10-22 AU AU73351/96A patent/AU7335196A/en not_active Abandoned
- 1996-10-22 WO PCT/JP1996/003068 patent/WO1997016538A1/ja active IP Right Grant
- 1996-10-22 KR KR1019980703189A patent/KR100552387B1/ko not_active IP Right Cessation
-
1998
- 1998-04-30 US US09/070,938 patent/US6723532B2/en not_active Expired - Lifetime
-
1999
- 1999-07-17 HK HK99103082A patent/HK1018287A1/xx not_active IP Right Cessation
- 1999-12-23 US US09/471,840 patent/US6645760B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100552387B1 (ko) | 2006-04-21 |
US20020100066A1 (en) | 2002-07-25 |
ATE298789T1 (de) | 2005-07-15 |
EP1325960A3 (en) | 2004-09-15 |
EP0864645A1 (en) | 1998-09-16 |
CN1118569C (zh) | 2003-08-20 |
KR20050084302A (ko) | 2005-08-26 |
EP0864645B1 (en) | 2005-06-29 |
EP1325960A2 (en) | 2003-07-09 |
CN1207123A (zh) | 1999-02-03 |
US6645760B2 (en) | 2003-11-11 |
DE69634904T2 (de) | 2006-05-18 |
HK1018287A1 (en) | 1999-12-17 |
WO1997016538A1 (fr) | 1997-05-09 |
US6723532B2 (en) | 2004-04-20 |
EP0864645B9 (en) | 2006-03-22 |
EP0864645A4 (en) | 2000-01-26 |
KR100754091B1 (ko) | 2007-08-31 |
DE69634904D1 (de) | 2005-08-04 |
KR19990067232A (ko) | 1999-08-16 |
US20020081706A1 (en) | 2002-06-27 |
AU7335196A (en) | 1997-05-22 |
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