[go: up one dir, main page]

DK0625912T3 - Behandling af inflammatorisk tarmsygdom - Google Patents

Behandling af inflammatorisk tarmsygdom

Info

Publication number
DK0625912T3
DK0625912T3 DK93904830.2T DK93904830T DK0625912T3 DK 0625912 T3 DK0625912 T3 DK 0625912T3 DK 93904830 T DK93904830 T DK 93904830T DK 0625912 T3 DK0625912 T3 DK 0625912T3
Authority
DK
Denmark
Prior art keywords
treatment
inflammatory bowel
bowel disease
tissus
ibd
Prior art date
Application number
DK93904830.2T
Other languages
Danish (da)
English (en)
Inventor
Roy R Lobb
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25268692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0625912(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of DK0625912T3 publication Critical patent/DK0625912T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70542—CD106
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93904830.2T 1992-02-12 1993-02-02 Behandling af inflammatorisk tarmsygdom DK0625912T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83513992A 1992-02-12 1992-02-12

Publications (1)

Publication Number Publication Date
DK0625912T3 true DK0625912T3 (da) 1997-10-27

Family

ID=25268692

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93904830.2T DK0625912T3 (da) 1992-02-12 1993-02-02 Behandling af inflammatorisk tarmsygdom

Country Status (11)

Country Link
EP (1) EP0625912B1 (fr)
JP (3) JPH07506566A (fr)
AT (1) ATE151642T1 (fr)
AU (1) AU674302B2 (fr)
CA (1) CA2129637C (fr)
DE (1) DE69309906T2 (fr)
DK (1) DK0625912T3 (fr)
ES (1) ES2103468T3 (fr)
GR (1) GR3024041T3 (fr)
HK (1) HK1007683A1 (fr)
WO (1) WO1993015764A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932214A (en) * 1994-08-11 1999-08-03 Biogen, Inc. Treatment for inflammatory bowel disease with VLA-4 blockers
ATE150975T1 (de) 1992-11-13 1997-04-15 Univ Washington Peripheralisierung hämatopoietischer stammzellen
AU727187B2 (en) * 1993-02-09 2000-12-07 Biogen Idec Ma Inc. Treatment for insulin dependent diabetes
DK0682529T4 (da) * 1993-02-09 2006-05-15 Biogen Idec Inc Antistof til behandling af insulinkrævende diabetes
ZA947006B (en) * 1993-09-15 1995-05-02 Univ Emory Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions
ES2270425T3 (es) * 1994-01-25 2007-04-01 Elan Pharmaceuticals, Inc. Anticuerpos humanizados contra la molecula de adhesion leucocitaria vla-4.
US5840299A (en) * 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US7435802B2 (en) 1994-01-25 2008-10-14 Elan Pharaceuticals, Inc. Humanized anti-VLA4 immunoglobulins
US7803904B2 (en) 1995-09-01 2010-09-28 Millennium Pharmaceuticals, Inc. Mucosal vascular addressing and uses thereof
US7750137B2 (en) 1995-09-01 2010-07-06 Millennium Pharmaceuticals, Inc. Mucosal vascular addressins
US6551593B1 (en) 1995-02-10 2003-04-22 Millennium Pharmaceuticals, Inc. Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) * 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US7618630B2 (en) 1998-09-14 2009-11-17 Board Of Regents, The University Of Texas System Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
TR200100734T2 (tr) 1998-09-14 2001-07-23 Board Of Regents, The University Of Texas System İntegrin antagonistlerini kullanarak multipl miyeloma ve miyeloma tarafından uyarılan kemik rezorpsiyonunun iyileştirilmesi
DE19922462A1 (de) 1999-05-17 2000-11-23 Aventis Pharma Gmbh Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10111877A1 (de) 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
AU2003211560A1 (en) 2002-02-20 2003-09-09 Ajinomoto Co., Inc. Novel phenylalanine derivative
EP1485127B1 (fr) 2002-02-25 2011-06-08 Elan Pharmaceuticals, Inc. Administration d'agents pour le traitement d'une inflammation
RU2390520C2 (ru) 2003-12-22 2010-05-27 Адзиномото Ко., Инк. Новые производные фенилаланина
WO2008103378A2 (fr) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Méthodes de traitement de la sclérose en plaques par administration d'une alpha-foetoprotéine combinée à un antagoniste de l'intégrine
JP4652356B2 (ja) 2007-02-26 2011-03-16 アルプス電気株式会社 ターンシグナルスイッチ装置
KR20110008086A (ko) 2008-04-11 2011-01-25 메리맥 파마슈티컬즈, 인크. 인간 혈청 알부민 링커 및 그 콘쥬게이트
WO2011130603A2 (fr) 2010-04-16 2011-10-20 Biogen Idec Ma Inc. Anticorps anti-vla-4
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
TWI698254B (zh) 2011-05-02 2020-07-11 美商千禧製藥公司 抗-α4β7抗體之調配物
CN109884295B (zh) * 2017-12-25 2022-03-08 苏州和锐生物科技有限公司 假单胞菌多肽、抗体捕获器件及试剂盒
CN119080931A (zh) 2018-06-04 2024-12-06 马萨诸塞州渤健公司 具有降低的效应功能的抗vla-4抗体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3852374T2 (de) * 1987-11-02 1995-05-04 Baylor College Medicine Verwendung von ICAM-1 oder ihre funktionelle Derivate zur Behandlung unspezifischer Entzündungen.
US5147637A (en) * 1988-06-07 1992-09-15 The Rockefeller University Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma
DK162890D0 (da) * 1990-07-06 1990-07-06 Novo Nordisk As Polypeptid
EP0610298A1 (fr) * 1991-10-01 1994-08-17 The General Hospital Corporation Prévention du rejet d'une allogreffe au moyen d'anticorps préparés contre des molécules d'adhésion

Also Published As

Publication number Publication date
WO1993015764A1 (fr) 1993-08-19
ATE151642T1 (de) 1997-05-15
JP2007045843A (ja) 2007-02-22
GR3024041T3 (en) 1997-10-31
CA2129637A1 (fr) 1993-08-19
JP4108572B2 (ja) 2008-06-25
AU3605993A (en) 1993-09-03
EP0625912B1 (fr) 1997-04-16
AU674302B2 (en) 1996-12-19
ES2103468T3 (es) 1997-09-16
EP0625912A1 (fr) 1994-11-30
DE69309906D1 (de) 1997-05-22
DE69309906T2 (de) 1997-11-06
CA2129637C (fr) 1999-05-04
HK1007683A1 (en) 1999-04-23
JPH07506566A (ja) 1995-07-20
JP2004002472A (ja) 2004-01-08

Similar Documents

Publication Publication Date Title
DK0625912T3 (da) Behandling af inflammatorisk tarmsygdom
ATE332159T1 (de) System zum sammeln von blut ohne es zu beschädigen
DK0626861T4 (da) Behandling af astma.
ATE113960T1 (de) Proteingewinnung.
FR2714327B1 (fr) Procédé et appareil de fixation d'un joint sur le bord périphérique d'un article.
RU95109441A (ru) Способ изготовления целлюлозного волокна и устройство для осуществления способа
ES2086521T3 (es) Proteina hibrida laci-factor x.
BG60017B2 (bg) Метод за намаляване хетерогенността на моноклонални антитела
EP0937982A3 (fr) Agent diagnostique et thérapeutique pour le traitement de l'hépatite auto-immune
DE69705721D1 (de) Verfahren zur Herstellung von 3-Isochromanon
FR2658197B1 (fr) Anticorps monoclonaux restreints reconnaissant un peptide associe a un antigene du complexe majeur d'histocompatibilite - applications au diagnostic et au traitement.
DE69435142D1 (de) Methoden zur Inhibition von HIV-assoziierten Krankheiten mittels monoklonaler Antikörper gegen sich selbstgerichtete zytotoxische T-Zellen
SE8904007D0 (sv) Monoklona antikroppar och diagnostiseringsmetod
DE69434087D1 (de) ENTEROTOXINE VON SHIGELLA FLEXNERI 2a
FR2710539B1 (fr) Ensemble d'aiguille chirurgicale.
FR2665643B1 (fr) Filtre d'aspiration.
DE69825976D1 (de) Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen
DE3850750D1 (de) Verfahren zur Verhütung von GVHD.
FI885025A0 (fi) Koagulationshaemmande protein pp4-x, dess framstaellning och anvaendning.
FR2737209B1 (fr) Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
DE69023500D1 (de) Verfahren zum nachweis von antikörpern gegen streptokinase.
EP0749981A4 (fr) Anticorps monoclonal
RU96109171A (ru) Способ идентификации тела погибшего
荒木雅弘 Klaus-Jurgen Engelberg:" Lexical Functional Grammar in Speech Recognition", Proc. of the 12th International Conference on Computational Linguistics, pp. 172-176 (1988).
RU93004826A (ru) Способ мездрения кож и шкур