ZA947006B - Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions - Google Patents
Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactionsInfo
- Publication number
- ZA947006B ZA947006B ZA947006A ZA947006A ZA947006B ZA 947006 B ZA947006 B ZA 947006B ZA 947006 A ZA947006 A ZA 947006A ZA 947006 A ZA947006 A ZA 947006A ZA 947006 B ZA947006 B ZA 947006B
- Authority
- ZA
- South Africa
- Prior art keywords
- reticulocytes
- vcam
- vla
- endothelium
- interfering
- Prior art date
Links
- 108010000134 Vascular Cell Adhesion Molecule-1 Proteins 0.000 title 1
- 210000003038 endothelium Anatomy 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000003993 interaction Effects 0.000 title 1
- 230000002452 interceptive effect Effects 0.000 title 1
- 210000001995 reticulocyte Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70542—CD106
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12222893A | 1993-09-15 | 1993-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA947006B true ZA947006B (en) | 1995-05-02 |
Family
ID=22401460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA947006A ZA947006B (en) | 1993-09-15 | 1994-09-12 | Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0720486A1 (en) |
AP (1) | AP9400679A0 (en) |
AU (1) | AU7835294A (en) |
WO (1) | WO1995007717A1 (en) |
ZA (1) | ZA947006B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11560433B2 (en) * | 2016-05-27 | 2023-01-24 | Albert Einstein College Of Medicine | Methods of treatment by targeting VCAM1 and MAEA |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL113261A (en) * | 1989-09-01 | 1996-10-16 | Hutchinson Fred Cancer Res | Repression by peptides of lymphocyte binding to vascular endothelium by interaction of extracellular uterine capacitor with connective tissue, and pharmaceutical preparations containing |
ES2102009T5 (en) * | 1992-01-13 | 2004-12-16 | Biogen Inc | TREATMENT FOR ASTHMA. |
ATE151642T1 (en) * | 1992-02-12 | 1997-05-15 | Biogen Inc | TREATMENT FOR INFLAMMATORY DISEASE OF THE INTESTINAL |
-
1994
- 1994-09-12 ZA ZA947006A patent/ZA947006B/en unknown
- 1994-09-13 AP APAP/P/1994/000679A patent/AP9400679A0/en unknown
- 1994-09-15 WO PCT/US1994/010395 patent/WO1995007717A1/en not_active Application Discontinuation
- 1994-09-15 EP EP94929205A patent/EP0720486A1/en not_active Withdrawn
- 1994-09-15 AU AU78352/94A patent/AU7835294A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU7835294A (en) | 1995-04-03 |
WO1995007717A1 (en) | 1995-03-23 |
AP9400679A0 (en) | 1996-03-13 |
EP0720486A1 (en) | 1996-07-10 |
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