DK0626861T4 - Behandling af astma. - Google Patents
Behandling af astma.Info
- Publication number
- DK0626861T4 DK0626861T4 DK93902914T DK93902914T DK0626861T4 DK 0626861 T4 DK0626861 T4 DK 0626861T4 DK 93902914 T DK93902914 T DK 93902914T DK 93902914 T DK93902914 T DK 93902914T DK 0626861 T4 DK0626861 T4 DK 0626861T4
- Authority
- DK
- Denmark
- Prior art keywords
- asthma
- treatment
- eosinophils
- polypeptide
- antibody
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title abstract 2
- 108010008212 Integrin alpha4beta1 Proteins 0.000 abstract 1
- 210000003979 eosinophil Anatomy 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70542—CD106
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82176892A | 1992-01-13 | 1992-01-13 | |
PCT/US1993/000030 WO1993013798A1 (en) | 1992-01-13 | 1993-01-12 | Treatment for asthma |
Publications (2)
Publication Number | Publication Date |
---|---|
DK0626861T3 DK0626861T3 (da) | 1997-09-22 |
DK0626861T4 true DK0626861T4 (da) | 2004-08-16 |
Family
ID=25234272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93902914T DK0626861T4 (da) | 1992-01-13 | 1993-01-12 | Behandling af astma. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0626861B2 (da) |
JP (4) | JPH07506091A (da) |
AT (1) | ATE150319T1 (da) |
CA (1) | CA2127462C (da) |
DE (1) | DE69309044T3 (da) |
DK (1) | DK0626861T4 (da) |
ES (1) | ES2102009T5 (da) |
GR (1) | GR3023203T3 (da) |
WO (1) | WO1993013798A1 (da) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5932214A (en) * | 1994-08-11 | 1999-08-03 | Biogen, Inc. | Treatment for inflammatory bowel disease with VLA-4 blockers |
AU689454B2 (en) | 1992-11-13 | 1998-04-02 | Board Of Regents Of The University Of Washington, The | Peripheralization of hematopoietic stem cells |
EP0678122B1 (en) * | 1993-01-12 | 1999-07-28 | Biogen, Inc. | Recombinant anti-vla4 antibody molecules |
CA2155303C (en) * | 1993-02-09 | 2010-04-20 | Linda C. Burkly | Treatment for insulin dependent diabetes |
AU727187B2 (en) * | 1993-02-09 | 2000-12-07 | Biogen Idec Ma Inc. | Treatment for insulin dependent diabetes |
ZA947006B (en) * | 1993-09-15 | 1995-05-02 | Univ Emory | Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions |
DE19647381A1 (de) | 1996-11-15 | 1998-05-20 | Hoechst Ag | Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten |
PL323130A1 (en) * | 1996-11-15 | 1998-05-25 | Hoechst Ag | Application of heterocyclic compounds in production of a pharmaceutic agent, novel heterocyclic compounds and pharmaceutic agent as such |
DE19741235A1 (de) | 1997-09-18 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
DE19741873A1 (de) * | 1997-09-23 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
DE19751251A1 (de) | 1997-11-19 | 1999-05-20 | Hoechst Marion Roussel De Gmbh | Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate |
DE19821483A1 (de) | 1998-05-14 | 1999-11-18 | Hoechst Marion Roussel De Gmbh | Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
US7618630B2 (en) | 1998-09-14 | 2009-11-17 | Board Of Regents, The University Of Texas System | Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists |
CN1236815C (zh) | 1998-09-14 | 2006-01-18 | 德克萨斯州立大学董事会 | 整联蛋白拮抗剂在制备治疗多发性骨髓瘤和骨髓瘤诱发的骨吸收的药物中的应用 |
WO2000064474A1 (en) | 1999-04-22 | 2000-11-02 | Biogen, Inc. | Method for the treatment of fibrosis using an antagonist of the integrin alpha-4 subunit |
DE19922462A1 (de) | 1999-05-17 | 2000-11-23 | Aventis Pharma Gmbh | Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate |
WO2000072881A1 (en) | 1999-06-01 | 2000-12-07 | Biogen, Inc. | A blocking monoclonal antibody to vla-1 and its use for the treatment of inflammatory disorders |
DE10111877A1 (de) | 2001-03-10 | 2002-09-12 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
ATE471344T1 (de) | 2001-04-13 | 2010-07-15 | Biogen Idec Inc | Antikörper gegen vla-1 |
DE10137595A1 (de) | 2001-08-01 | 2003-02-13 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung |
ATE464299T1 (de) | 2002-02-20 | 2010-04-15 | Ajinomoto Kk | Neues phenylalaninderivat |
AU2004303696B2 (en) | 2003-12-22 | 2011-03-31 | Ea Pharma Co., Ltd. | Novel phenylalanine derivative |
GB0521621D0 (en) * | 2005-10-24 | 2005-11-30 | Domantis Ltd | Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases |
AU2007267579B2 (en) | 2006-05-25 | 2013-05-30 | Biogen Ma Inc. | Methods of treating stroke |
US20100150915A1 (en) | 2007-02-20 | 2010-06-17 | Stewart Edward J | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
WO2009126920A2 (en) | 2008-04-11 | 2009-10-15 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
EP3202789B1 (en) | 2010-04-16 | 2020-05-06 | Biogen MA Inc. | Anti-vla-4 antibodies |
EP2814468B1 (en) | 2012-02-16 | 2019-06-19 | Santarus, Inc. | Anti-vla1 (cd49a) antibody pharmaceutical compositions |
EP3800999A4 (en) | 2018-06-04 | 2022-06-01 | Biogen MA Inc. | ANTI-VLA-4 ANTIBODY WITH REDUCED EFFECTIVE FUNCTION |
US11597770B2 (en) | 2020-01-24 | 2023-03-07 | Pfizer Inc. | Anti-E-selectin antibodies, compositions and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) † | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
GB8607679D0 (en) † | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
IL113261A (en) † | 1989-09-01 | 1996-10-16 | Hutchinson Fred Cancer Res | Inhibition by peptides of lymphocyte adherence to vascular endothelium utilizing an extracellular matrix receptor-ligand interaction and pharmaceutical compositions containing said peptides |
DK162890D0 (da) | 1990-07-06 | 1990-07-06 | Novo Nordisk As | Polypeptid |
-
1993
- 1993-01-12 CA CA002127462A patent/CA2127462C/en not_active Expired - Lifetime
- 1993-01-12 DE DE69309044T patent/DE69309044T3/de not_active Expired - Lifetime
- 1993-01-12 EP EP93902914A patent/EP0626861B2/en not_active Expired - Lifetime
- 1993-01-12 WO PCT/US1993/000030 patent/WO1993013798A1/en active IP Right Grant
- 1993-01-12 JP JP5512512A patent/JPH07506091A/ja not_active Withdrawn
- 1993-01-12 DK DK93902914T patent/DK0626861T4/da active
- 1993-01-12 ES ES93902914T patent/ES2102009T5/es not_active Expired - Lifetime
- 1993-01-12 AT AT93902914T patent/ATE150319T1/de active
-
1997
- 1997-04-21 GR GR970400864T patent/GR3023203T3/el unknown
-
2002
- 2002-09-30 JP JP2002286910A patent/JP4590152B2/ja not_active Expired - Lifetime
-
2006
- 2006-08-10 JP JP2006218925A patent/JP2006316070A/ja not_active Withdrawn
-
2010
- 2010-07-27 JP JP2010168709A patent/JP2010285444A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE69309044T2 (de) | 1997-09-25 |
AU665232B2 (en) | 1995-12-21 |
GR3023203T3 (en) | 1997-07-30 |
HK1007682A1 (en) | 1999-04-23 |
JP4590152B2 (ja) | 2010-12-01 |
JPH07506091A (ja) | 1995-07-06 |
CA2127462A1 (en) | 1993-07-22 |
EP0626861B1 (en) | 1997-03-19 |
DK0626861T3 (da) | 1997-09-22 |
WO1993013798A1 (en) | 1993-07-22 |
ES2102009T3 (es) | 1997-07-16 |
JP2006316070A (ja) | 2006-11-24 |
AU3431793A (en) | 1993-08-03 |
DE69309044D1 (de) | 1997-04-24 |
JP2003176239A (ja) | 2003-06-24 |
JP2010285444A (ja) | 2010-12-24 |
EP0626861A1 (en) | 1994-12-07 |
EP0626861B2 (en) | 2004-04-28 |
ATE150319T1 (de) | 1997-04-15 |
CA2127462C (en) | 1999-03-23 |
DE69309044T3 (de) | 2004-12-23 |
ES2102009T5 (es) | 2004-12-16 |
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