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DE69924842D1 - Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus - Google Patents

Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Info

Publication number
DE69924842D1
DE69924842D1 DE69924842T DE69924842T DE69924842D1 DE 69924842 D1 DE69924842 D1 DE 69924842D1 DE 69924842 T DE69924842 T DE 69924842T DE 69924842 T DE69924842 T DE 69924842T DE 69924842 D1 DE69924842 D1 DE 69924842D1
Authority
DE
Germany
Prior art keywords
preventing
pruritus
tuber
root
treating inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69924842T
Other languages
English (en)
Other versions
DE69924842T2 (de
Inventor
Embden Geertruida Ruseler-Van
Lieshout Maria Van
Daniel Laman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Skintec Bv Lelystad Nl
Original Assignee
Erasmus Universiteit Rotterdam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erasmus Universiteit Rotterdam filed Critical Erasmus Universiteit Rotterdam
Publication of DE69924842D1 publication Critical patent/DE69924842D1/de
Application granted granted Critical
Publication of DE69924842T2 publication Critical patent/DE69924842T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/56—Protease inhibitors from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
DE69924842T 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus Expired - Lifetime DE69924842T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98201694A EP0958833A1 (de) 1998-05-20 1998-05-20 Verfahren und Mittel zur Vorbeugung oder Behandlung der Entzündung
EP98201694 1998-05-20
PCT/NL1999/000312 WO1999059623A1 (en) 1998-05-20 1999-05-20 Methods and means for preventing or treating inflammation or pruritis

Publications (2)

Publication Number Publication Date
DE69924842D1 true DE69924842D1 (de) 2005-05-25
DE69924842T2 DE69924842T2 (de) 2006-02-16

Family

ID=8233748

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924842T Expired - Lifetime DE69924842T2 (de) 1998-05-20 1999-05-20 Knollen- oder wurzel-gewonnene proteaseinhibitoren zur vorbeugung oder behandlung von entzündung oder pruritus

Country Status (11)

Country Link
US (1) US6723354B1 (de)
EP (2) EP0958833A1 (de)
JP (1) JP4633926B2 (de)
AT (1) ATE293455T1 (de)
AU (1) AU768615B2 (de)
CA (1) CA2332370C (de)
DE (1) DE69924842T2 (de)
DK (1) DK1079853T3 (de)
ES (1) ES2245510T3 (de)
NZ (1) NZ508406A (de)
WO (1) WO1999059623A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1061963B1 (de) 1998-03-12 2003-05-07 The Procter & Gamble Company Protease-inhibitoren für absorbierende artikel
US6703536B2 (en) 1998-03-12 2004-03-09 The Procter & Gamble Company Disposable absorbent article having a skin care composition containing an enzyme inhibitor
US6207596B1 (en) 1998-11-09 2001-03-27 The Procter & Gamble Company Disposable premoistened wipe containing an antimicrobial protease inhibitor
ITMI20020756A1 (it) * 2002-04-09 2003-10-09 Sinclair Pharma S R L Composizioni farmaceutiche topiche per il trattamento delle dermatiti
FR2865133B1 (fr) * 2004-01-19 2008-01-18 Rytek Compositions pour le traitement de pathologies digestives
US7858836B2 (en) * 2004-12-27 2010-12-28 Convatec Technologies Inc. Enzyme inhibiting adhesives
NZ547991A (en) * 2005-06-22 2008-08-29 Bristol Myers Squibb Co Enzyme inhibiting sprayable skin barrier compositions comprising enzyme inhibitors derived from potatoes
US7749497B2 (en) 2005-12-06 2010-07-06 Ocera Therapeutics, Inc. Use of adsorbent carbon microspheres for the treatment of irritable bowel syndrome
EP1920662A1 (de) 2006-11-10 2008-05-14 Coöperatie Avebe U.A. Natives Kartoffelproteinisolat
WO2008069649A1 (en) * 2006-11-10 2008-06-12 Coöperatie Avebe U.A. Protein gel formation
WO2008086069A1 (en) * 2007-01-03 2008-07-17 The General Hospital Corporation Methods of treating itch
EP2115000A1 (de) * 2007-01-29 2009-11-11 Upfront Chromatography A/S Isolierung und aufreinigung von minimal denaturierten kartoffelproteinen und peptiden
EP2192178B1 (de) 2007-09-20 2015-11-18 Kao Corporation B-glucuronidasehemmer
US20090148538A1 (en) * 2007-10-12 2009-06-11 Ocera Therapeutics, Inc. Use of adsorbent carbon microspheres to treat pouchitis
BRPI0822305B8 (pt) 2008-02-25 2021-06-22 Teikoku Seiyaku Kk material de hidrogel protetor de feridas
US8852569B2 (en) * 2008-08-28 2014-10-07 The General Hospital Corporation Prevention and treatment of itch with cysteine protease inhibition
US8817379B2 (en) 2011-07-12 2014-08-26 Google Inc. Whole image scanning mirror display system
US8471967B2 (en) 2011-07-15 2013-06-25 Google Inc. Eyepiece for near-to-eye display with multi-reflectors
US8670000B2 (en) 2011-09-12 2014-03-11 Google Inc. Optical display system and method with virtual image contrast control
US8786686B1 (en) 2011-09-16 2014-07-22 Google Inc. Head mounted display eyepiece with integrated depth sensing
PL406918A1 (pl) 2014-01-24 2015-08-03 Uniwersytet Przyrodniczy W Poznaniu Sposób otrzymywania preparatu z soku ziemniaka oraz jego zastosowanie
WO2016118632A1 (en) 2015-01-20 2016-07-28 The General Hospital Corporation Prevention and treatment of itch with an mrgpr antagonist
DK3283093T3 (da) * 2015-04-17 2020-11-09 Eurodrug Laboratories B V Kombination af mindst en proteaseinhibitor og dexpanthenol til anvendelse i forebyggelsen og/eller behandlingen af hudlæsioner
CN107303395B (zh) * 2016-04-19 2021-07-30 北京泰德制药股份有限公司 一种含有链霉蛋白酶的药物组合物及其制备方法
CN114007580B (zh) * 2019-07-03 2023-12-05 科洛普拉斯特公司 皮肤护理组合物
WO2021086999A1 (en) * 2019-10-29 2021-05-06 The Regents Of The University Of California Therapeutic approach for treating inflammatory bowel disease

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BE754278A (fr) * 1969-08-02 1971-02-01 Bayer Ag Procede d'utilisation d'inhibiteurs biologiques de proteases comme desodorisants
JPH0694420B2 (ja) * 1983-03-31 1994-11-24 恒 美原 血栓溶解剤
JPS61126031A (ja) * 1984-11-26 1986-06-13 Agency Of Ind Science & Technol コロニ−形成刺激因子の製造法
US4906457A (en) * 1988-09-06 1990-03-06 Washington State University Research Foundation, Inc. Compositions and methods for reducing the risk of sunlight and ultraviolet induced skin cancer
CA2047702C (en) * 1989-03-06 2000-10-24 Joseph F. Sambrook Serpin resistant chymotrypsin superfamily proteases particularly pai-1 resistant t-pa, complementary inhibitor mutants; compositions; genes; expression
FR2651125B1 (fr) * 1989-08-23 1992-10-02 Roussel Uclaf Compositions pharmaceutiques de type "pates a l'eau".
JPH0398596A (ja) * 1989-09-11 1991-04-24 Chisso Corp モノクローナル抗体
JP2938507B2 (ja) * 1990-03-20 1999-08-23 株式会社日本触媒 紙おむつ
DE4107765A1 (de) * 1990-07-28 1992-01-30 Schebo Tech Medizinisch Biolog Pankreas-elastase-1-spezifischer antikoerper, ein verfahren zu seiner gewinnung und ein testkit der solche antikoerper enthaelt
JPH04178335A (ja) * 1990-11-09 1992-06-25 Taiyo Kagaku Co Ltd ウイルス性下痢症治療剤
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JP3159509B2 (ja) * 1992-03-30 2001-04-23 サンスター株式会社 プロテアーゼ阻害剤
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DE69333782T2 (de) * 1992-12-16 2006-01-26 Hexima Ltd., Melbourne Ein proteinase-inhibitor, vorläufer davon und dafür kodierende genetische sequenzen
WO1995012408A1 (en) * 1993-11-04 1995-05-11 Brigham & Women's Hospital Plasmin-independent fibrinolysis
JP3432260B2 (ja) * 1993-11-07 2003-08-04 日本水産株式会社 魚肉水溶性タンパク質の分画濃縮物を主要成分とする食品物性改良剤
US5614198A (en) * 1995-07-25 1997-03-25 The Trustees Of The University Of Pennsylvania Bowman-Birk Inhibitor compositions for treatment of inflammatory disease
JP3945544B2 (ja) * 1995-12-27 2007-07-18 ピジョン株式会社 ダイズエキスの製造方法
GB2311727A (en) * 1996-03-28 1997-10-08 Hanson Shaw Beverley Jane Sanitary article with treatment substance

Also Published As

Publication number Publication date
JP2002515454A (ja) 2002-05-28
AU768615B2 (en) 2003-12-18
CA2332370A1 (en) 1999-11-25
ATE293455T1 (de) 2005-05-15
DK1079853T3 (da) 2005-08-29
EP0958833A1 (de) 1999-11-24
AU4064299A (en) 1999-12-06
EP1079853B1 (de) 2005-04-20
US6723354B1 (en) 2004-04-20
WO1999059623A1 (en) 1999-11-25
DE69924842T2 (de) 2006-02-16
EP1079853A1 (de) 2001-03-07
NZ508406A (en) 2003-08-29
ES2245510T3 (es) 2006-01-01
CA2332370C (en) 2012-01-24
JP4633926B2 (ja) 2011-02-16

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SKINTEC B.V., LELYSTAD, NL

8364 No opposition during term of opposition