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DE69919863D1 - Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels - Google Patents

Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels

Info

Publication number
DE69919863D1
DE69919863D1 DE69919863T DE69919863T DE69919863D1 DE 69919863 D1 DE69919863 D1 DE 69919863D1 DE 69919863 T DE69919863 T DE 69919863T DE 69919863 T DE69919863 T DE 69919863T DE 69919863 D1 DE69919863 D1 DE 69919863D1
Authority
DE
Germany
Prior art keywords
gel
mixture
stable
aqueous
oily
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69919863T
Other languages
English (en)
Other versions
DE69919863T2 (de
DE69919863T8 (de
Inventor
Jean-Marc Aiache
Pascale Gauthier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ardana Bioscience Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26234356&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69919863(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9806958A external-priority patent/FR2779438B1/fr
Application filed by Individual filed Critical Individual
Publication of DE69919863D1 publication Critical patent/DE69919863D1/de
Publication of DE69919863T2 publication Critical patent/DE69919863T2/de
Application granted granted Critical
Publication of DE69919863T8 publication Critical patent/DE69919863T8/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08Cellulose derivatives
    • C08L1/26Cellulose ethers
    • C08L1/28Alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69919863T 1998-06-03 1999-06-03 Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels Active DE69919863T8 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9806958A FR2779438B1 (fr) 1998-06-03 1998-06-03 Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant
FR9806958 1998-06-03
US204089 1998-12-03
US09/204,089 US6187323B1 (en) 1998-06-03 1998-12-03 Stable gel mixture in the form of a mixture of oleogel and aqueous gel, process for its preparation, pharmaceutical and cosmetic compositions comprising it, and use of the pharmaceutical compositions
PCT/IB1999/001068 WO1999062497A1 (en) 1998-06-03 1999-06-03 Stable gel mixture in the form of a mixture of oleogel and aqueous gel

Publications (3)

Publication Number Publication Date
DE69919863D1 true DE69919863D1 (de) 2004-10-07
DE69919863T2 DE69919863T2 (de) 2005-09-01
DE69919863T8 DE69919863T8 (de) 2005-12-15

Family

ID=26234356

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919863T Active DE69919863T8 (de) 1998-06-03 1999-06-03 Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels

Country Status (6)

Country Link
EP (1) EP1083880B1 (de)
AT (1) ATE274900T1 (de)
AU (1) AU3951399A (de)
DE (1) DE69919863T8 (de)
ES (1) ES2228044T3 (de)
WO (1) WO1999062497A1 (de)

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AU2002950506A0 (en) * 2002-07-31 2002-09-12 Soltec Research Pty Ltd Percutaneous delivery system
GB0524961D0 (en) * 2005-12-07 2006-01-18 Pharmakodex Ltd Transdermal administration of active agents for systemic effect
MA29127B1 (fr) * 2006-06-30 2008-01-02 Yahya Bensouda Formulation d'une emulsion lipidique pour nutrition parenterale a base d'huile d'argane
GB2445539A (en) * 2006-12-29 2008-07-16 Ardana Bioscience Ltd Bigel composition
CA2763644C (en) 2009-06-12 2017-05-23 Mars, Incorporated Polymer gelation of oils
GB2485421B (en) 2010-11-15 2016-05-25 Mars Inc Dough products exhibiting reduced oil migration
DK2646506T3 (da) 2010-12-01 2019-01-02 Coavel Inc Tiksotrope sammensætninger
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3936133A1 (de) 2011-11-23 2022-01-12 TherapeuticsMD, Inc. Natürliche kombinationshormonersatzformulierungen und therapien
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PL3469914T3 (pl) 2012-09-28 2025-06-23 Mars, Incorporated Czekolada odporna na ciepło
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
FR3002444B1 (fr) 2013-02-25 2015-03-13 Oreal Composition cosmetique de type gel
FR3002449B1 (fr) 2013-02-25 2015-04-03 Oreal Composition cosmetique de type gel
FR3002448B1 (fr) * 2013-02-25 2015-04-03 Oreal Composition cosmetique de type gel
FR3004343B1 (fr) 2013-04-12 2015-06-19 Oreal Composition cosmetique de type gel
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
FR3021533B1 (fr) 2014-05-28 2017-09-15 Oreal Composition cosmetique de type gel
AU2015296609A1 (en) 2014-07-29 2016-12-22 Therapeuticsmd, Inc. Transdermal cream
WO2016030839A1 (fr) 2014-08-28 2016-03-03 L'oreal Composition gel/gel comprenant un filtre uv
FR3025100B1 (fr) 2014-08-28 2016-12-09 Oreal Composition cosmetique de type gel a tenue amelioree
FR3025098B1 (fr) * 2014-08-28 2018-03-09 Oreal Composition cosmetique de type gel facilement demaquillable
FR3025096B1 (fr) 2014-08-28 2016-12-23 Oreal Composition gel/gel contenant un actif anti-transpirant
FR3025097B1 (fr) 2014-08-28 2016-12-23 Oreal Gel/gel comprenant au moins deux charges a effet flouteur
FR3025099B1 (fr) * 2014-08-28 2016-12-16 Oreal Composition cosmetique de type gel a tenue amelioree et non collante
FR3028753B1 (fr) * 2014-11-24 2018-01-05 L'oreal Gel aqueux ou hydroalcoolique de phyllosilicates synthetiques a titre d'agent viscosant, matifiant et/ou homogeneisant d'application
FR3030261B1 (fr) 2014-12-18 2017-01-13 Oreal Composition comprenant des particules de polymere stabilise et un polymere filmogene hydrophobe
DE102015207624A1 (de) 2015-04-27 2016-10-27 Beiersdorf Ag Hautpflegezubereitung
DE102015207621A1 (de) 2015-04-27 2016-10-27 Beiersdorf Ag Hautreinigungszubereitung
ES2813584T3 (es) 2015-12-17 2021-03-24 Oreal Composición de tipo gel/gel basada en pigmentos recubiertos hidrófobos y un ácido graso líquido y/o un compuesto de glicol
AU2017206048B2 (en) * 2016-01-07 2023-04-13 Viramal Limited Gel compositions for transdermal delivery to maximize drug concentrations in the stratum corneum and serum and methods of use thereof
FR3067934B1 (fr) 2017-06-27 2019-08-09 L'oreal Composition gelifiee comprenant une dispersion d'agregats solides.
FR3067937B1 (fr) 2017-06-27 2019-12-20 L'oreal Composition gel-gel comprenant une cire a l'etat cristallin.
KR102692643B1 (ko) * 2017-11-10 2024-08-06 (주)아모레퍼시픽 바이겔 타입의 화장료 조성물
FR3075053B1 (fr) 2017-12-15 2020-07-10 L'oreal Composition de type gel/gel a base de pigments, d’au moins un dihydroxyalcane lineaire sature en c3-c8, d’acide salicylique sous forme libre
FR3076218B1 (fr) 2017-12-28 2019-12-27 L'oreal Composition gelifiee comprenant une microdispersion aqueuse de cire(s)
CN113164384A (zh) 2018-10-26 2021-07-23 维拉莫有限公司 黏膜粘附性凝胶组合物
ES2948955T3 (es) 2018-11-30 2023-09-22 Viramal Ltd Un método de preparación de un agente gelificante, el agente gelificante obtenido de este modo y el uso de dicho agente gelificante
FR3090327B1 (fr) 2018-12-20 2020-12-25 Oreal Composition gélifiée comprenant deux gélifiants hydrophiles et des agrégats solides
FR3090325B1 (fr) 2018-12-21 2021-01-01 Oreal Composition du type gel/gel comprenant des particules de nitrure de bore et au moins un pigment encapsule
DE102019119888A1 (de) * 2019-07-23 2021-01-28 Fachhochschule Bielefeld Neue Formulierung auf Basis eines Oleogels insbesondere zur Freisetzung von volatilen Komponenten und Verfahren zu dessen Herstellung
EP4003287A1 (de) * 2019-07-24 2022-06-01 Shiseido Company, Ltd. Wasser-in-öl emulsion mit emolliens und verfahren zu deren verwendung
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
EP3922235A1 (de) 2020-06-11 2021-12-15 Viramal Limited Hydroalkoholisches gel und verfahren zu seiner herstellung
WO2023283652A1 (en) * 2021-07-08 2023-01-12 Minutri Inc. Gel compositions with high thermal stability and methods of making the same
CN114191381B (zh) * 2021-11-29 2023-10-24 华南农业大学 一种温敏型模拟塑性脂肪、口腔质构及消化行为可控的双凝胶及其制备和应用
CN116271198A (zh) * 2021-12-21 2023-06-23 中国科学院理化技术研究所 一种自导出敷料及其制备方法
CN115429703B (zh) * 2022-10-24 2023-09-22 中国热带农业科学院农产品加工研究所 双凝胶组合物及其制备方法

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Publication number Priority date Publication date Assignee Title
FR2635463A1 (fr) * 1988-08-19 1990-02-23 Veprol Composition pharmaceutique comportant un principe actif peu soluble dans l'eau et au moins un glyceride gelifie par au moins un polymere cellulosique
GB9207988D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Topical composition
KR970064620A (ko) * 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물

Also Published As

Publication number Publication date
ATE274900T1 (de) 2004-09-15
DE69919863T2 (de) 2005-09-01
EP1083880B1 (de) 2004-09-01
AU3951399A (en) 1999-12-20
ES2228044T3 (es) 2005-04-01
DE69919863T8 (de) 2005-12-15
EP1083880A1 (de) 2001-03-21
WO1999062497A1 (en) 1999-12-09

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