DE69916042D1 - Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin - Google Patents

Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin

Info

Publication number: DE69916042D1
Authority: DE; Germany
Prior art keywords: piperidyliden; cyclohepta; benzo; dihydro; pyridine
Prior art date: 1998-07-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69916042T

Other languages

English (en)

Other versions

DE69916042T2 (de

Inventor

H Kou

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-07-10

Filing date

1999-07-08

Publication date

2004-05-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22348307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69916042(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-07-08 Application filed by Schering Corp filed Critical Schering Corp

2004-05-06 Application granted granted Critical

2004-05-06 Publication of DE69916042D1 publication Critical patent/DE69916042D1/de

2004-11-11 Publication of DE69916042T2 publication Critical patent/DE69916042T2/de

2019-07-09 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Otolaryngology (AREA)
Inorganic Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DE69916042T 1998-07-10 1999-07-08 Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin Expired - Lifetime DE69916042T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11323298A	1998-07-10	1998-07-10
US113232		1998-07-10
PCT/US1999/012368 WO2000002560A1 (en)	1998-07-10	1999-07-08	8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE ORAL COMPOSITIONS

Publications (2)

Publication Number	Publication Date
DE69916042D1 true DE69916042D1 (de)	2004-05-06
DE69916042T2 DE69916042T2 (de)	2004-11-11

Family

ID=22348307

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE69916042T Expired - Lifetime DE69916042T2 (de)	1998-07-10	1999-07-08	Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin
DE69940932T Expired - Lifetime DE69940932D1 (de)	1998-07-10	1999-07-08	Orale Zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidylene)-5H-benzoÄ5,6Ü-cyclo-heptaÄ1,2-bÜpyridin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE69940932T Expired - Lifetime DE69940932D1 (de)	1998-07-10	1999-07-08	Orale Zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidylene)-5H-benzoÄ5,6Ü-cyclo-heptaÄ1,2-bÜpyridin

Country Status (27)

Country	Link
EP (3)	EP2055303A3 (de)
JP (4)	JP3224379B1 (de)
KR (1)	KR100420641B1 (de)
CN (1)	CN1145485C (de)
AR (4)	AR016044A1 (de)
AT (2)	ATE262904T1 (de)
AU (1)	AU741201B2 (de)
BR (1)	BR9910449A (de)
CA (2)	CA2325014C (de)
CY (1)	CY1109279T1 (de)
CZ (1)	CZ300843B6 (de)
DE (2)	DE69916042T2 (de)
DK (2)	DK1073438T3 (de)
ES (2)	ES2214871T3 (de)
HU (1)	HU228448B1 (de)
ID (1)	ID28645A (de)
IL (1)	IL139407A0 (de)
MY (1)	MY116038A (de)
NO (1)	NO331454B1 (de)
NZ (2)	NZ507885A (de)
PE (1)	PE20000761A1 (de)
PL (1)	PL199390B1 (de)
PT (2)	PT1380297E (de)
SK (1)	SK288240B6 (de)
TW (1)	TW575424B (de)
WO (1)	WO2000002560A1 (de)
ZA (1)	ZA200006224B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK287684B6 (sk)	1999-12-20	2011-06-06	Schering Corporation	Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním
SK287105B6 (sk)	1999-12-20	2009-12-07	Schering Corporation	Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním
US7405223B2 (en)	2000-02-03	2008-07-29	Schering Corporation	Treating allergic and inflammatory conditions
US7507714B2 (en)	2000-09-27	2009-03-24	Bayer Corporation	Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
JP2008506679A (ja) *	2004-07-16	2008-03-06	シプラ・リミテッド	抗ヒスタミン組成物
TW200804358A (en)	2006-03-31	2008-01-16	Res Found Itsuu Lab	Novel compound having heterocycle
WO2009066773A1 (ja)	2007-11-21	2009-05-28	Dainippon Sumitomo Pharma Co., Ltd.	口腔内崩壊錠
TR200806298A2 (tr)	2008-08-22	2010-03-22	Bi̇lgi̇ç Mahmut	Farmasötik formülasyon
ATE525064T1 (de)	2009-07-01	2011-10-15	Tiefenbacher Alfred E Gmbh & Co Kg	Pharmazeutische zusammensetzung mit desloratadin
ES2709487T3 (es)	2010-05-10	2019-04-16	Lesvi Laboratorios Sl	Formulaciones farmacéuticas estables que contienen un antihistamínico

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61501205A (ja) *	1984-02-15	1986-06-19	シェリング・コ−ポレ−ション	８↓−クロル↓−６，１１↓−ジヒドロ↓−１１↓−（４↓−ピペリジリデン）↓−５Ｈ↓−ベンゾ〔５，６〕シクロヘプタ〔１，２−ｂ〕ピリジンおよびその塩、これらの化合物の製造方法、ならびにこれらの化合物を含有する医薬組成物
US4657716A (en)	1984-03-19	1987-04-14	Lim Kunststoff Technologie Gesellschaft	Method of making elastomeric shoe soles
US4990535A (en) *	1989-05-03	1991-02-05	Schering Corporation	Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
US5595997A (en)	1994-12-30	1997-01-21	Sepracor Inc.	Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
TW522014B (en) *	1997-02-07	2003-03-01	Sepracor Inc	Lactose-free, non-hygroscopic and anhydrous pharmaceutical unit dosage form containing descarboethoxyloratadine

1999
- 1999-07-08 DK DK99933484T patent/DK1073438T3/da active
- 1999-07-08 DE DE69916042T patent/DE69916042T2/de not_active Expired - Lifetime
- 1999-07-08 EP EP09002742A patent/EP2055303A3/de not_active Withdrawn
- 1999-07-08 KR KR10-2000-7012430A patent/KR100420641B1/ko not_active Expired - Lifetime
- 1999-07-08 NZ NZ507885A patent/NZ507885A/en not_active IP Right Cessation
- 1999-07-08 AT AT99933484T patent/ATE262904T1/de active
- 1999-07-08 DE DE69940932T patent/DE69940932D1/de not_active Expired - Lifetime
- 1999-07-08 EP EP03023240A patent/EP1380297B1/de not_active Expired - Lifetime
- 1999-07-08 DK DK03023240T patent/DK1380297T3/da active
- 1999-07-08 WO PCT/US1999/012368 patent/WO2000002560A1/en not_active Ceased
- 1999-07-08 SK SK1711-2000A patent/SK288240B6/sk not_active IP Right Cessation
- 1999-07-08 CA CA002325014A patent/CA2325014C/en not_active Expired - Lifetime
- 1999-07-08 IL IL13940799A patent/IL139407A0/xx not_active IP Right Cessation
- 1999-07-08 ES ES99933484T patent/ES2214871T3/es not_active Expired - Lifetime
- 1999-07-08 NZ NZ512916A patent/NZ512916A/xx not_active IP Right Cessation
- 1999-07-08 CN CNB998068497A patent/CN1145485C/zh not_active Expired - Lifetime
- 1999-07-08 JP JP2000558820A patent/JP3224379B1/ja not_active Expired - Lifetime
- 1999-07-08 PT PT03023240T patent/PT1380297E/pt unknown
- 1999-07-08 AT AT03023240T patent/ATE432075T1/de active
- 1999-07-08 BR BR9910449-0A patent/BR9910449A/pt not_active Application Discontinuation
- 1999-07-08 PL PL344045A patent/PL199390B1/pl unknown
- 1999-07-08 CZ CZ20004056A patent/CZ300843B6/cs unknown
- 1999-07-08 ES ES03023240T patent/ES2326214T3/es not_active Expired - Lifetime
- 1999-07-08 EP EP99933484A patent/EP1073438B1/de not_active Revoked
- 1999-07-08 AU AU49531/99A patent/AU741201B2/en not_active Expired
- 1999-07-08 ID IDW20010070A patent/ID28645A/id unknown
- 1999-07-08 AR ARP990103342A patent/AR016044A1/es not_active Application Discontinuation
- 1999-07-08 HU HU0101900A patent/HU228448B1/hu unknown
- 1999-07-08 PT PT99933484T patent/PT1073438E/pt unknown
- 1999-07-08 CA CA002377178A patent/CA2377178A1/en not_active Abandoned
- 1999-07-09 PE PE1999000697A patent/PE20000761A1/es not_active IP Right Cessation
- 1999-07-09 MY MYPI99002889A patent/MY116038A/en unknown
- 1999-07-09 TW TW088111680A patent/TW575424B/zh not_active IP Right Cessation
2000
- 2000-07-17 AR ARP000103668A patent/AR021158A2/es unknown
- 2000-07-17 AR ARP000103667A patent/AR021157A2/es unknown
- 2000-07-17 AR ARP000103669A patent/AR021159A1/es not_active Application Discontinuation
- 2000-10-31 NO NO20005485A patent/NO331454B1/no not_active IP Right Cessation
- 2000-11-01 ZA ZA200006224A patent/ZA200006224B/xx unknown
2001
- 2001-07-04 JP JP2001204138A patent/JP4160739B2/ja not_active Expired - Lifetime
2005
- 2005-07-08 JP JP2005200665A patent/JP4621082B2/ja not_active Expired - Lifetime
2009
- 2009-08-10 CY CY20091100846T patent/CY1109279T1/el unknown
2010
- 2010-08-26 JP JP2010190099A patent/JP2010265329A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
CA2325014A1 (en)	2000-01-20
NO20005485L (no)	2001-03-09
CY1109279T1 (el)	2012-05-23
NZ512916A (en)	2003-03-28
ATE432075T1 (de)	2009-06-15
CN1303284A (zh)	2001-07-11
JP4160739B2 (ja)	2008-10-08
IL139407A0 (en)	2001-11-25
KR20010043402A (ko)	2001-05-25
JP2010265329A (ja)	2010-11-25
DE69916042T2 (de)	2004-11-11
EP1380297A1 (de)	2004-01-14
TW575424B (en)	2004-02-11
KR100420641B1 (ko)	2004-03-02
BR9910449A (pt)	2001-01-02
EP2055303A3 (de)	2009-12-16
DK1380297T3 (da)	2009-08-17
JP2002520285A (ja)	2002-07-09
AR021159A1 (es)	2002-06-12
CA2377178A1 (en)	2000-01-20
ES2326214T3 (es)	2009-10-05
AR016044A1 (es)	2001-06-20
ATE262904T1 (de)	2004-04-15
JP2005298524A (ja)	2005-10-27
PL344045A1 (en)	2001-09-24
JP2002068983A (ja)	2002-03-08
EP1380297B1 (de)	2009-05-27
HK1030361A1 (en)	2001-05-04
AR021158A2 (es)	2002-06-12
CA2325014C (en)	2002-05-28
NO20005485D0 (no)	2000-10-31
AU741201B2 (en)	2001-11-22
CN1145485C (zh)	2004-04-14
CZ20004056A3 (cs)	2001-03-14
CZ300843B6 (cs)	2009-08-26
EP2055303A2 (de)	2009-05-06
MY116038A (en)	2003-10-31
AR021157A2 (es)	2002-06-12
SK288240B6 (sk)	2015-02-03
EP1073438A1 (de)	2001-02-07
AU4953199A (en)	2000-02-01
PL199390B1 (pl)	2008-09-30
NO331454B1 (no)	2012-01-09
JP3224379B1 (ja)	2001-10-29
HU228448B1 (en)	2013-03-28
ZA200006224B (en)	2001-11-01
NZ507885A (en)	2001-08-31
HUP0101900A2 (hu)	2001-11-28
SK17112000A3 (sk)	2001-12-03
JP4621082B2 (ja)	2011-01-26
ID28645A (id)	2001-06-21
DE69940932D1 (de)	2009-07-09
EP1073438B1 (de)	2004-03-31
PT1073438E (pt)	2004-07-30
PT1380297E (pt)	2009-07-06
ES2214871T3 (es)	2004-09-16
IL139407A (en)	2001-10-31
DK1073438T3 (da)	2004-05-10
WO2000002560A1 (en)	2000-01-20
HUP0101900A3 (en)	2003-01-28
PE20000761A1 (es)	2000-08-31

Publication	Publication Date	Title
LU90738I2 (fr)	2001-05-09	Desloratadine
NZ222253A (en)	1990-08-28	6,11-dihydro-11-(4-piperidylidene)-5h-benzo c5,6,)cyclohepta c1,2-b)pyridine derivatives and pharmaceutical compositions
DE69916042D1 (de)	2004-05-06	Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin
NO996547L (no)	2000-03-01	Polymorfer av 8-klor-6,11-dihydro-11-(4-piperidyliden)-5H- benzo[5,6]syklohepta[1,2-b]pyridin
DE60008073D1 (de)	2004-03-11	Furo[3,2-b]pyridine als 5-ht1f agonisten
NO20004906D0 (no)	2000-09-29	PDE IV-inhiberende pyridinderivater
AU2003230758A1 (en)	2003-10-20	5h-benzo(4,5)cyclohepta(1,2-b)pyridine nmda/nr2b antagonists
DE60001054D1 (de)	2003-01-30	Trizyclische pyridin n-oxide vasopressin agonisten
IL133449A0 (en)	2001-04-30	Benzo (5, 6) cyclohepta (1, 2-b) pyridine derivatives as farnesyl protein transferase inhibitors
AU9683798A (en)	1999-05-03	Ethyl 4-(8-chloro-5, 6-dihydro-11h- benzo{5,6}cyclohepta {1,2-b}pyridin -11-ylidene)-1- piperidene carboxylate polymorph
NZ231726A (en)	1990-08-28	6,11 dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridines and pharmaceutical compositions
ZA877919B (en)	1989-06-28	6,11-dihydro-11-(4-piperidylidene)-5h-benzo(5,6)cyclohepta(1,2-b)pyridines and compositions and methods of use

Legal Events

Date	Code	Title	Description
2005-03-31	8363	Opposition against the patent