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DE69732049D1 - Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika - Google Patents

Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika

Info

Publication number
DE69732049D1
DE69732049D1 DE69732049T DE69732049T DE69732049D1 DE 69732049 D1 DE69732049 D1 DE 69732049D1 DE 69732049 T DE69732049 T DE 69732049T DE 69732049 T DE69732049 T DE 69732049T DE 69732049 D1 DE69732049 D1 DE 69732049D1
Authority
DE
Germany
Prior art keywords
hyaluronic acid
pharmaceutical preparations
local anesthetics
containing salts
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69732049T
Other languages
English (en)
Other versions
DE69732049T2 (de
Inventor
Aurelio Romeo
Bruno Silvestrini
Gunter Kirschner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of DE69732049D1 publication Critical patent/DE69732049D1/de
Application granted granted Critical
Publication of DE69732049T2 publication Critical patent/DE69732049T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
DE69732049T 1996-10-17 1997-10-17 Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika Expired - Lifetime DE69732049T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITPD960254 1996-10-17
IT96PD000254A IT1287967B1 (it) 1996-10-17 1996-10-17 Preparazioni farmaceutiche per uso anestetico locale
PCT/IB1997/001288 WO1998017285A1 (en) 1996-10-17 1997-10-17 Pharmaceutical preparations comprised of salts of hyaluronic acid with local anaesthetics

Publications (2)

Publication Number Publication Date
DE69732049D1 true DE69732049D1 (de) 2005-01-27
DE69732049T2 DE69732049T2 (de) 2006-03-02

Family

ID=11391550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69732049T Expired - Lifetime DE69732049T2 (de) 1996-10-17 1997-10-17 Pharmazeutische zubereitungen, enthaltend salze von hyaluronsäure und lokalanästhetika

Country Status (14)

Country Link
US (1) US6224857B1 (de)
EP (1) EP0956026B1 (de)
JP (1) JP4334620B2 (de)
KR (1) KR20000049281A (de)
AT (1) ATE285241T1 (de)
AU (1) AU712927B2 (de)
BR (1) BR9713486A (de)
CA (1) CA2268967C (de)
DE (1) DE69732049T2 (de)
ES (1) ES2235254T3 (de)
HK (1) HK1023518A1 (de)
IT (1) IT1287967B1 (de)
TR (1) TR199900860T2 (de)
WO (1) WO1998017285A1 (de)

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ES2617452T3 (es) 2002-08-28 2017-06-19 Apollo Endosurgery, Inc Dispositivo de banda gástrica resistente a la fatiga
DE10246340A1 (de) * 2002-10-04 2004-04-29 Wohlrab, David, Dr. Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung
US7238677B2 (en) * 2003-03-28 2007-07-03 Kimberly-Clark Worldwide, Inc. Prevention of urogenital infections
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
JP4672302B2 (ja) * 2003-08-05 2011-04-20 天藤製薬株式会社 安定な局所麻酔組成物
US20050095219A1 (en) * 2003-10-29 2005-05-05 Shu-Ping Yang Compositions for promoting vaginal cell proliferation and maturation
AU2005208721B2 (en) 2004-01-23 2010-09-23 Boston Scientific Scimed, Inc. Releasably-securable one-piece adjustable gastric band
MXPA06010204A (es) 2004-03-08 2007-03-07 Endoart Sa Sistema de cierre para organos tubulares.
AU2004317849B2 (en) 2004-03-18 2011-03-31 Allergan, Inc. Apparatus and method for volume adjustment of intragastric balloons
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
US20070264296A1 (en) * 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US7993675B2 (en) 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US8088095B2 (en) * 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
EP2152743A2 (de) * 2007-05-23 2010-02-17 Allergan, Inc. Quervernetztes collagen und anwendungen davon
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) * 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
KR101577471B1 (ko) 2007-11-16 2015-12-14 알러간, 인코포레이티드 자색반병의 치료를 위한 조성물 및 방법
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
ES2759373T3 (es) 2008-06-12 2020-05-08 Medtronic Xomed Inc Producto para el tratamiento de heridas crónicas con un sistema extracelular de solvatación de sustancias poliméricas
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
AU2009288118B2 (en) 2008-09-02 2014-12-11 Allergan, Inc. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
EP2346324A4 (de) * 2008-10-06 2012-10-10 Microbial Defense Systems Llc Antimikrobielle zusammensetzung sowie verfahren zu ihrer herstellung und verwendung
WO2010042493A1 (en) 2008-10-06 2010-04-15 Allergan, Inc. Mechanical gastric band with cushions
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
US8390326B2 (en) * 2009-05-05 2013-03-05 William Marsh Rice University Method for fabrication of a semiconductor element and structure thereof
US20120277199A1 (en) 2009-10-21 2012-11-01 Otonomy, Inc. Modulation of Gel Temperature of Poloxamer-Containing Formulations
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
CA2792729C (en) * 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
WO2012154953A2 (en) 2011-05-10 2012-11-15 Microbial Defense Systems, Llc Antimicrobial solid and methods of making and using same
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
KR102015676B1 (ko) 2011-06-03 2019-10-21 알러간, 인코포레이티드 항산화제를 포함하는 피부 충전제 조성물
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
EP2581079B1 (de) 2011-10-11 2016-12-07 BioPolymer GmbH & Co. KG Kombination aus Hyaluronsäure und Prilocain
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
EP2985019B1 (de) 2014-08-16 2021-10-20 Church & Dwight Co., Inc. Nasale Zusammensetzung mit antiviralen Eigenschaften
EP2985027B1 (de) 2014-08-16 2021-03-31 Church & Dwight Co., Inc. Nasenheilmittel enthaltend ein gemisch von hyaluronsäuren und salzlösung
EP3200838B1 (de) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stabile hydrogelzusammensetzungen mit additiven
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
CN106187864B (zh) * 2016-07-11 2018-11-23 江苏天和制药有限公司 一种由盐酸布比卡因制备高纯度布比卡因碱的方法
IT201800001890A1 (it) * 2018-01-25 2019-07-25 Fidia Farm Spa Composizioni farmaceutiche per il trattamento del dolore postoperatorio
EP3977881B1 (de) 2020-09-04 2024-06-19 Bert Raf Celis Sportbekleidung für das fahrradfahren und zugehörige kühlverfahren

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229075B (it) * 1985-04-05 1991-07-17 Fidia Farmaceutici Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
LU85582A1 (fr) * 1983-10-11 1985-06-04 Fidia Spa Fractions d'acide hyaluronique ayant une activite pharmaceutique,procedes pour leur preparation et compositions pharmaceutiques les contenant
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1247175B (it) 1991-04-19 1994-12-12 Fidia Spa Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.
DE69632569T2 (de) * 1995-06-09 2005-08-18 Euroceltique S.A. Formulierungen und verfahren für eine verlängerte lokalanästhesie

Also Published As

Publication number Publication date
ATE285241T1 (de) 2005-01-15
JP2001503042A (ja) 2001-03-06
AU4470097A (en) 1998-05-15
JP4334620B2 (ja) 2009-09-30
US6224857B1 (en) 2001-05-01
TR199900860T2 (xx) 1999-06-21
BR9713486A (pt) 2000-04-11
ITPD960254A1 (it) 1998-04-17
WO1998017285A1 (en) 1998-04-30
CA2268967A1 (en) 1998-04-30
CA2268967C (en) 2003-02-04
HK1023518A1 (en) 2000-09-15
KR20000049281A (ko) 2000-07-25
EP0956026A1 (de) 1999-11-17
EP0956026B1 (de) 2004-12-22
AU712927B2 (en) 1999-11-18
IT1287967B1 (it) 1998-09-10
ES2235254T3 (es) 2005-07-01
DE69732049T2 (de) 2006-03-02

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