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DE69729228D1 - Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe - Google Patents

Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe

Info

Publication number
DE69729228D1
DE69729228D1 DE69729228T DE69729228T DE69729228D1 DE 69729228 D1 DE69729228 D1 DE 69729228D1 DE 69729228 T DE69729228 T DE 69729228T DE 69729228 T DE69729228 T DE 69729228T DE 69729228 D1 DE69729228 D1 DE 69729228D1
Authority
DE
Germany
Prior art keywords
drug delivery
matrix material
polyetherester copolymers
polyetherester
glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69729228T
Other languages
English (en)
Other versions
DE69729228T2 (de
Inventor
Jacob Hildebrand Goedemoed
Wilhelmus Everhardus Hennink
Jeroen Mattijs Bezemer
Jan Feijen
Blitterswijk Clemens Van
Bruijn Joost Dick De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octoplus Polyactive Sciences Bv Leiden Nl
OctoPlus Sciences BV
Biolex Therapeutics Inc
Original Assignee
Chienna BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chienna BV filed Critical Chienna BV
Application granted granted Critical
Publication of DE69729228D1 publication Critical patent/DE69729228D1/de
Publication of DE69729228T2 publication Critical patent/DE69729228T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69729228T 1996-08-16 1997-08-18 Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe Expired - Lifetime DE69729228T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US699896 1996-08-16
US08/699,896 US5980948A (en) 1996-08-16 1996-08-16 Polyetherester copolymers as drug delivery matrices

Publications (2)

Publication Number Publication Date
DE69729228D1 true DE69729228D1 (de) 2004-06-24
DE69729228T2 DE69729228T2 (de) 2005-05-04

Family

ID=24811379

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69729228T Expired - Lifetime DE69729228T2 (de) 1996-08-16 1997-08-18 Polyetherester-Copolymere als Matrixmaterial für die Arzneistoffabgabe
DE69726672T Expired - Lifetime DE69726672T2 (de) 1996-08-16 1997-08-18 Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69726672T Expired - Lifetime DE69726672T2 (de) 1996-08-16 1997-08-18 Polyätherester-Copolymere als Matrixmaterialien für die Arzneistoffabgabe

Country Status (9)

Country Link
US (1) US5980948A (de)
EP (2) EP1247522B1 (de)
AT (2) ATE267006T1 (de)
CA (1) CA2213368C (de)
DE (2) DE69729228T2 (de)
DK (2) DK1247522T3 (de)
ES (2) ES2221916T3 (de)
PT (2) PT830859E (de)
WO (1) WO1998006439A1 (de)

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US5980948A (en) 1999-11-09
DE69729228T2 (de) 2005-05-04
CA2213368A1 (en) 1998-02-16
PT1247522E (pt) 2004-10-29
EP0830859B1 (de) 2003-12-10
EP0830859A3 (de) 1998-07-22
WO1998006439A1 (en) 1998-02-19
DK1247522T3 (da) 2004-09-27
DE69726672D1 (de) 2004-01-22
ES2221916T3 (es) 2005-01-16
CA2213368C (en) 2008-04-01
ATE255884T1 (de) 2003-12-15
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EP1247522B1 (de) 2004-05-19
EP1247522A1 (de) 2002-10-09

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Owner name: OCTOPLUS SCIENCES B.V., LEIDEN, NL