[go: up one dir, main page]

DE69604285D1 - Polysiloxan-polyol makromere, deren herstellung und verwendung - Google Patents

Polysiloxan-polyol makromere, deren herstellung und verwendung

Info

Publication number
DE69604285D1
DE69604285D1 DE69604285T DE69604285T DE69604285D1 DE 69604285 D1 DE69604285 D1 DE 69604285D1 DE 69604285 T DE69604285 T DE 69604285T DE 69604285 T DE69604285 T DE 69604285T DE 69604285 D1 DE69604285 D1 DE 69604285D1
Authority
DE
Germany
Prior art keywords
polysiloxane
production
macromers
polyol
polyol macromers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69604285T
Other languages
English (en)
Other versions
DE69604285T2 (de
Inventor
Angelika Domschke
Dieter Lohmann
Jens Hoepken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25687828&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69604285(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08569816 external-priority patent/US5760100B1/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69604285D1 publication Critical patent/DE69604285D1/de
Application granted granted Critical
Publication of DE69604285T2 publication Critical patent/DE69604285T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00Producing optical elements, e.g. lenses or prisms
    • B29D11/00009Production of simple or compound lenses
    • B29D11/00038Production of contact lenses
    • B29D11/00076Production of contact lenses enabling passage of fluids, e.g. oxygen, tears, between the area under the lens and the lens exterior
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00Processes for applying liquids or other fluent materials
    • B05D1/62Plasma-deposition of organic layers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/42Casting under special conditions, e.g. vacuum
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/4833Polyethers containing oxyethylene units
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/50Polyethers having heteroatoms other than oxygen
    • C08G18/5003Polyethers having heteroatoms other than oxygen having halogens
    • C08G18/5015Polyethers having heteroatoms other than oxygen having halogens having fluorine atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/61Polysiloxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/67Unsaturated compounds having active hydrogen
    • C08G18/671Unsaturated compounds having only one group containing active hydrogen
    • C08G18/672Esters of acrylic or alkyl acrylic acid having only one group containing active hydrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/81Unsaturated isocyanates or isothiocyanates
    • C08G18/8108Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
    • C08G18/8116Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group esters of acrylic or alkylacrylic acid having only one isocyanate or isothiocyanate group
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/81Unsaturated isocyanates or isothiocyanates
    • C08G18/8141Unsaturated isocyanates or isothiocyanates masked
    • C08G18/815Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen
    • C08G18/8158Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen with unsaturated compounds having only one group containing active hydrogen
    • C08G18/8175Polyisocyanates or polyisothiocyanates masked with unsaturated compounds having active hydrogen with unsaturated compounds having only one group containing active hydrogen with esters of acrylic or alkylacrylic acid having only one group containing active hydrogen
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C71/00After-treatment of articles without altering their shape; Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2011/00Optical elements, e.g. lenses, prisms
    • B29L2011/0016Lenses
    • B29L2011/0041Contact lenses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/903Interpenetrating network
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/936Encapsulated chemical agent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/937Utility as body contact e.g. implant, contact lens or I.U.D.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Plasma & Fusion (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Silicon Polymers (AREA)
  • Eyeglasses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE69604285T 1995-05-19 1996-05-07 Polysiloxan-polyol makromere, deren herstellung und verwendung Expired - Lifetime DE69604285T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH149695 1995-05-19
US08569816 US5760100B1 (en) 1994-09-06 1995-12-08 Extended wear ophthalmic lens
PCT/EP1996/001888 WO1996036890A1 (en) 1995-05-19 1996-05-07 Polysiloxane-polyol macromers, their preparation and their use

Publications (2)

Publication Number Publication Date
DE69604285D1 true DE69604285D1 (de) 1999-10-21
DE69604285T2 DE69604285T2 (de) 2000-03-23

Family

ID=25687828

Family Applications (2)

Application Number Title Priority Date Filing Date
DE29624309U Expired - Lifetime DE29624309U1 (de) 1995-04-04 1996-03-22 Dauertraglinsen
DE69604285T Expired - Lifetime DE69604285T2 (de) 1995-05-19 1996-05-07 Polysiloxan-polyol makromere, deren herstellung und verwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE29624309U Expired - Lifetime DE29624309U1 (de) 1995-04-04 1996-03-22 Dauertraglinsen

Country Status (19)

Country Link
US (1) US6043328A (de)
EP (1) EP0826158B1 (de)
JP (2) JP5048173B2 (de)
KR (1) KR19990021832A (de)
CN (1) CN1186550A (de)
AR (1) AR001497A1 (de)
AT (1) ATE184708T1 (de)
AU (1) AU5814496A (de)
BR (1) BR9608824A (de)
CA (1) CA2220217A1 (de)
CZ (1) CZ363997A3 (de)
DE (2) DE29624309U1 (de)
HU (1) HUP9801139A3 (de)
IL (1) IL118237A0 (de)
NO (1) NO975289L (de)
PL (1) PL323350A1 (de)
SI (1) SI0819258T1 (de)
WO (1) WO1996036890A1 (de)
ZA (1) ZA963937B (de)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6357854A (ja) * 1986-08-29 1988-03-12 Aisin Seiki Co Ltd スタ−リング機関の作動ガス圧力制御装置
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6200626B1 (en) * 1999-05-20 2001-03-13 Bausch & Lomb Incorporated Surface-treatment of silicone medical devices comprising an intermediate carbon coating and graft polymerization
KR100719796B1 (ko) * 1999-10-07 2007-05-21 존슨 앤드 존슨 비젼 케어, 인코포레이티드 실리콘 하이드로겔의 제조에 유용한 마크로머
JP2001163933A (ja) * 1999-10-27 2001-06-19 Novartis Ag 材料表面を改質する方法
US7521519B1 (en) * 2000-03-14 2009-04-21 Novartis Ag Organic compounds
US6770721B1 (en) * 2000-11-02 2004-08-03 Surface Logix, Inc. Polymer gel contact masks and methods and molds for making same
WO2002052045A1 (en) * 2000-12-26 2002-07-04 Aviva Biosciences Active and biocompatible platforms prepared by polymerization of surface coating films
US20050276858A1 (en) * 2001-04-23 2005-12-15 Kao Weiyuan J Bifunctional-modified hydrogels
EP1423093A4 (de) * 2001-04-23 2005-11-30 Wisconsin Alumni Res Found Bifunktional modifizierte hydrogele
US20030032874A1 (en) * 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
AU2003263085A1 (en) * 2002-09-06 2004-03-29 Quarter Lambda Technologies, Inc. Hybrid contact lens system and method
US7322694B2 (en) * 2002-09-06 2008-01-29 Synergeyes, Inc. Hybrid contact lens system and method
US7104648B2 (en) * 2002-09-06 2006-09-12 Synergeyes, Inc. Hybrid contact lens system and method
US7163292B2 (en) * 2002-09-06 2007-01-16 Synergeyes, Inc. Hybrid contact lens system and method
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
US7109280B2 (en) * 2003-10-29 2006-09-19 Council Of Scientific And Industrial Research Block copolymers and preparation thereof
US20050096446A1 (en) * 2003-10-29 2005-05-05 Council Of Scientific And Industrial Tri-block copolymers and a process for the preparation of the same
US7018039B2 (en) 2003-11-14 2006-03-28 Synergeyes,Inc. Contact lens
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7354980B1 (en) 2004-03-12 2008-04-08 Key Medical Technologies, Inc. High refractive index polymers for ophthalmic applications
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
DE102004025130A1 (de) * 2004-05-18 2005-12-08 Universitätsklinikum Hamburg-Eppendorf Körperschaft des Öffentlichen Rechts Verfahren und Vorrichtung zur Untersuchung von Sludgeablagerungen auf Materialien für Endoprothesen sowie Endoprothese
US9248614B2 (en) * 2004-06-30 2016-02-02 Novartis Ag Method for lathing silicone hydrogel lenses
US20060004165A1 (en) * 2004-06-30 2006-01-05 Phelan John C Silicone hydrogels with lathability at room temperature
US7654956B2 (en) 2004-07-13 2010-02-02 Dexcom, Inc. Transcutaneous analyte sensor
HUE044130T2 (hu) 2004-08-27 2019-09-30 Coopervision Int Holding Co Lp Szilikon-hidrogél kontaktlencsék
US9322958B2 (en) 2004-08-27 2016-04-26 Coopervision International Holding Company, Lp Silicone hydrogel contact lenses
US7446157B2 (en) 2004-12-07 2008-11-04 Key Medical Technologies, Inc. Nanohybrid polymers for ophthalmic applications
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
WO2006098408A1 (ja) * 2005-03-17 2006-09-21 Dow Corning Toray Co., Ltd. ジヒドロキシカルボン酸アミド基含有オルガノポリシロキサンおよびその製造方法
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US7543936B2 (en) * 2005-05-06 2009-06-09 Synergeyes, Inc. Hybrid contact lens system and method of fitting
CN101228311A (zh) * 2005-05-23 2008-07-23 陶氏康宁公司 含糖-硅氧烷共聚物的表面处理组合物
EP1885331A2 (de) * 2005-05-23 2008-02-13 Dow Corning Corporation Körperpflegezusammensetzungen mit saccharid-siloxan-copolymeren
US7377637B2 (en) * 2005-10-11 2008-05-27 Synergeyes, Inc. Hybrid contact lens system and method of fitting
US20070092831A1 (en) * 2005-10-24 2007-04-26 Bausch & Lomb Incorporated Radiation-absorbing polymeric materials and ophthalmic devices comprising same
US20070092830A1 (en) * 2005-10-24 2007-04-26 Bausch & Lomb Incorporated Polymeric radiation-absorbing materials and ophthalmic devices comprising same
WO2007120381A2 (en) 2006-04-14 2007-10-25 Dexcom, Inc. Analyte sensor
JP2013076097A (ja) * 2006-04-25 2013-04-25 Hitachi Chemical Co Ltd 硬化性樹脂組成物及び光学部材
JP5239169B2 (ja) * 2006-04-25 2013-07-17 日立化成株式会社 光学部材
US7576159B2 (en) * 2006-04-28 2009-08-18 Bausch & Lomb Incorporated Gas-permeable materials and medical devices
US7537339B2 (en) * 2006-05-25 2009-05-26 Synergeyes, Inc. Hybrid contact lens system and method of fitting
US7468397B2 (en) * 2006-06-30 2008-12-23 Bausch & Lomb Incorporated Polymerizable siloxane-quaternary amine copolymers
EP1892877B1 (de) * 2006-08-25 2008-12-03 Alcatel Lucent Digitalsignalempfänger mit Q-Faktorüberwachung
US20080074611A1 (en) * 2006-09-22 2008-03-27 Meyers William E Hybrid contact lens with improved resistance to flexure and method for designing the same
KR101514472B1 (ko) * 2007-03-22 2015-04-22 노파르티스 아게 친수성 중합체성 사슬이 있는 실리콘-함유 예비중합체
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7828432B2 (en) * 2007-05-25 2010-11-09 Synergeyes, Inc. Hybrid contact lenses prepared with expansion controlled polymeric materials
WO2008154312A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4098177A1 (de) 2007-10-09 2022-12-07 DexCom, Inc. Integriertes insulin-abgabesystem mit kontinuierlichem glucosesensor
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US8290559B2 (en) 2007-12-17 2012-10-16 Dexcom, Inc. Systems and methods for processing sensor data
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2010033724A2 (en) 2008-09-19 2010-03-25 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
TWI509312B (zh) * 2009-10-01 2015-11-21 Coopervision Int Holding Co Lp 聚矽氧水凝膠隱形眼鏡及製造聚矽氧水凝膠隱形眼鏡的方法
BR112012017972A2 (pt) * 2010-02-16 2016-03-29 Toray Industries lente maleável e método para produzir uma lente maleável para os olhos com baixo teor de água
EP2638878B1 (de) 2010-07-30 2019-10-23 Novartis AG Silikon-hydrogel-linsen mit wasserreichen oberflächen
AU2011282603B2 (en) 2010-07-30 2014-01-30 Novartis Ag Amphiphilic polysiloxane prepolymers and uses thereof
KR101858022B1 (ko) 2010-08-23 2018-05-16 다우 실리콘즈 코포레이션 수성 환경에서 안정한 당 실록산 및 그러한 당 실록산의 제조 및 사용 방법
HUE044765T2 (hu) 2010-10-06 2019-11-28 Novartis Ag Polimerizálható hosszabbított láncú polisziloxánok hidrofil oldalcsoportokkal
JP5852659B2 (ja) 2010-10-06 2016-02-03 ノバルティス アーゲー 水処理可能なシリコーン含有プレポリマー及びその使用
JP5640153B2 (ja) 2010-10-06 2014-12-10 ノバルティス アーゲー ダングリング親水性ポリマー鎖を有する連鎖延長ポリシロキサン架橋剤
ES2533693T3 (es) 2011-02-28 2015-04-14 Coopervision International Holding Company, Lp Lentes de contacto de hidrogel que contiene fosfina
MY161370A (en) 2011-02-28 2017-04-14 Coopervision Int Holding Co Lp Wettable silicon hydrogel contact lenses
MY162458A (en) 2011-02-28 2017-06-15 Coopervision Int Holding Co Lp Silicone hydrogel contact lenses
TWI512048B (zh) 2011-02-28 2015-12-11 Coopervision Int Holding Co Lp 聚矽氧水凝膠隱形眼鏡
MY151110A (en) 2011-02-28 2014-04-15 Coopervision Int Holding Co Lp Dimensionally stable silicone hydrogel contact lenses
HUE043683T2 (hu) 2011-02-28 2019-09-30 Coopervision Int Holding Co Lp Szilikon hidrogél kontaktlencsék elfogadható energiaveszteség-szintekkel
TWI512355B (zh) 2011-02-28 2015-12-11 Coopervision Int Holding Co Lp 聚矽氧水凝膠隱形眼鏡及相關組合物及方法
CN102199270B (zh) * 2011-04-08 2012-07-25 江苏君锐高新材料有限公司 聚氨酯树脂预聚体溶液及其制备的人造革雾洗亮涂饰剂
US20140123981A1 (en) * 2011-06-30 2014-05-08 Koninklijke Philips N.V. Skin-contact product having moisture and microclimate control
ES2877234T3 (es) * 2011-08-17 2021-11-16 Toray Industries Lente ocular blanda con bajo contenido de humedad y método para su fabricación
HUE029018T2 (en) 2011-10-12 2017-02-28 Novartis Ag A method for producing UV absorbing contact lenses by coating
DE102011055683A1 (de) 2011-11-24 2013-05-29 Götz von Foerster Synthetisches Schmiermittel zur Verwendung als Synovialflüssigkeitsersatz
WO2014039495A1 (en) 2012-09-05 2014-03-13 University Of Miami Novel keratoprosthesis, and system and method of corneal repair using same
EP2931732B1 (de) 2012-12-14 2020-11-25 Alcon Inc. Vinylmonomere mit amphiphilem siloxan und verwendungen davon
JP6065988B2 (ja) 2012-12-14 2017-01-25 ノバルティス アーゲー トリス(トリメチルシロキシ)シランビニル系モノマー及びその用途
EP2931767B1 (de) 2012-12-14 2017-11-08 Novartis AG (meth)acrylamide mit amphiphilem siloxan und verwendungen davon
CN104871036B (zh) 2012-12-17 2019-12-10 诺华股份有限公司 制备改进的uv吸收性眼用透镜的方法
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
JP6241042B2 (ja) * 2013-02-21 2017-12-06 東レ株式会社 医療デバイス
CA2907441C (en) 2013-03-21 2023-05-23 Shifamed Holdings, Llc Accommodating intraocular lens
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
WO2015052229A1 (en) * 2013-10-08 2015-04-16 Momentive Performance Materials Gmbh Reactive functional siloxane compositions
US9505778B2 (en) 2013-11-27 2016-11-29 Regents Of The University Of Minnesota Monomers, polymers and articles containing the same from sugar derived compounds
HUE038809T2 (hu) 2013-12-17 2018-11-28 Novartis Ag Térhálósított hidrofíl bevonattal ellátott szilikon hidrogél lencse
JP6355821B2 (ja) 2014-04-25 2018-07-11 ノバルティス アーゲー カルボシロキサンビニル系モノマー
WO2015164582A1 (en) 2014-04-25 2015-10-29 Novartis Ag Hydrophilized carbosiloxane vinylic monomers
JP6356635B2 (ja) * 2014-06-12 2018-07-11 信越化学工業株式会社 眼科デバイス製造用モノマー
JP6173260B2 (ja) 2014-06-12 2017-08-02 信越化学工業株式会社 眼科デバイス製造用モノマー
JP6267832B2 (ja) 2014-08-26 2018-01-24 シファメド・ホールディングス・エルエルシー 調節式眼内レンズ
WO2016032926A1 (en) 2014-08-26 2016-03-03 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
NZ728772A (en) 2014-09-26 2018-10-26 Novartis Ag Polymerizable polysiloxanes with hydrophilic substituents
CN106032400A (zh) * 2015-03-17 2016-10-19 专力国际开发股份有限公司 网状高分子、用于制作生医装置的组成物及生医装置
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
US10138316B2 (en) 2015-12-15 2018-11-27 Novartis Ag Amphiphilic branched polydiorganosiloxane macromers
WO2017103793A1 (en) 2015-12-15 2017-06-22 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
CN105949692A (zh) * 2016-07-22 2016-09-21 上海洛法化工有限公司 一种改性聚乙烯醇及其制备工艺
EP3515961A1 (de) * 2016-09-19 2019-07-31 Dow Silicones Corporation Polyurethan-polyorganosiloxan-copolymer und verfahren zu dessen herstellung
JP6783931B2 (ja) 2016-10-26 2020-11-11 アルコン インク. 両親媒性分枝鎖状ポリジオルガノシロキサンマクロマー
US10858517B2 (en) * 2016-12-09 2020-12-08 Momentive Performance Materials Korea Co., Ltd. Composition for organic electronic element encapsulant and encapsulant formed using same
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
JP6954679B2 (ja) 2016-12-23 2021-10-27 シファメド・ホールディングス・エルエルシー マルチピース調節式眼内レンズ、及び同を作成し、使用するための方法
EP3634308A4 (de) 2017-05-30 2021-02-24 Shifamed Holdings, LLC Oberflächenbehandlungen zur aufnahme von intraokularlinsen und zugehörige verfahren und vorrichtungen
CA3066081A1 (en) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Adjustable optical power intraocular lenses
CN209606445U (zh) 2017-10-24 2019-11-08 德克斯康公司 预连接分析物传感器
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
MX2020006077A (es) 2017-12-13 2020-08-24 Alcon Inc Lentes de contacto con gradiente acuoso desechables semanal y mensualmente.
CN112512494B (zh) * 2018-12-29 2024-03-15 瓦克化学股份公司 亲水性的含环糊精的有机硅凝胶
EP4112672A4 (de) * 2020-02-25 2024-03-13 Shiseido Company, Ltd. Harzmaterial mit einem siloxanbindungshaltigen polymer mit wirtsgruppe und/oder gastgruppe

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE104988C (de) *
US4777276A (en) * 1981-10-29 1988-10-11 Minnesota Mining And Manufacturing Company Acrylamidoacylated oligomers
US4820302A (en) * 1982-04-22 1989-04-11 Sterling Drug Inc. Bio compatible and blood compatible materials and methods
DE3219220A1 (de) * 1982-05-21 1983-11-24 Wacker-Chemie GmbH, 8000 München Waessrige, organosiliciumverbindung enthaltende zusammensetzungen
JPS5982212A (ja) * 1982-11-03 1984-05-12 Sanshin Shokai:Kk フリ−フロ−コンベヤ
GB2166654A (en) * 1984-09-22 1986-05-14 Olusola Olumide Akindele Oni Shoulder joint prosthesis
US4605712A (en) * 1984-09-24 1986-08-12 Ciba-Geigy Corporation Unsaturated polysiloxanes and polymers thereof
US4591652A (en) * 1985-04-12 1986-05-27 Scm Corporation Polyhydroxyl silanes or siloxanes
US4623697A (en) * 1985-04-30 1986-11-18 Ppg Industries, Inc. Ungelled resins containing hydrolyzable moieties from organosilane compounds
JPS6268820A (ja) * 1985-09-19 1987-03-28 Kao Corp 糖残基を含有するオルガノポリシロキサンの製造法
JPS63139106A (ja) * 1986-12-02 1988-06-10 Kao Corp 化粧料
DE3641436A1 (de) * 1986-12-04 1988-06-09 Schmalbach Lubeca Loesungsmittelfreie, monomerarme bzw. -freie, polymerisierbare schmelzmasse, verfahren zu deren herstellung und verarbeitung
FR2622201B1 (fr) * 1987-10-23 1990-03-23 Essilor Int Elastomere de silicones mouillable convenant a la fabrication de lentilles de contact
DE3803628A1 (de) * 1988-02-06 1989-08-17 Bayer Ag Verwendung von aminogruppen aufweisenden polysiloxanen als zusatzmittel in kunststofflacken
DE3832089A1 (de) * 1988-09-21 1990-03-29 Rotta Gmbh & Co Dr Textilveredelungsmittel und verfahren zur ausruestung von cellulosehaltigem textilgut
US4983702A (en) * 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
US4962178A (en) * 1988-11-03 1990-10-09 Ciba-Geigy Corporation Novel polysiloxane-polyurethanes and contact lens thereof
US5010141A (en) * 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
JPH06102796B2 (ja) * 1990-01-10 1994-12-14 花王株式会社 衣料用液体洗浄剤組成物
US5057377A (en) * 1990-05-16 1991-10-15 Ciba-Geigy Corporation Fluorinated silicon polymers
CA2065923C (en) * 1992-04-13 1997-06-24 Richard Nolin Method and apparatus for harvesting and dewatering peat moss material
JPH05339087A (ja) * 1992-06-05 1993-12-21 Japan Steel Works Ltd:The 堆肥化装置の曝気方法
DE59305382D1 (de) * 1992-08-05 1997-03-20 Ciba Geigy Ag Kontaktlinsen aus lipophilisierten Cyclodextrinen
JP3195662B2 (ja) * 1992-08-24 2001-08-06 株式会社メニコン 眼用レンズ材料
DE4318536A1 (de) * 1993-06-04 1994-12-08 Bayer Ag Siloxanylmodifizierte polyhydroxylierte Kohlenwasserstoffe
DE4318539A1 (de) * 1993-06-04 1994-12-08 Bayer Ag Anionische siloxanylmodifizierte polyhydroxylierte Kohlenwasserstoffe
DE4318537A1 (de) * 1993-06-04 1994-12-08 Bayer Ag Kationische siloxanylmodifizierte polyhydroxylierte Kohlenwasserstoffe
US5603774A (en) * 1993-09-27 1997-02-18 Alcon Laboratories, Inc. Method for reducing tackiness of soft acrylic polymers
JPH08269204A (ja) * 1995-03-29 1996-10-15 Chiba Seifun Kk 新規シリコーン誘導体、その製造法および用途
US5648402A (en) * 1995-06-01 1997-07-15 Nunez; Ivan M. Contact lenses from highly permeable siloxane polyol material

Also Published As

Publication number Publication date
HUP9801139A2 (hu) 1998-09-28
PL323350A1 (en) 1998-03-30
NO975289D0 (no) 1997-11-18
CA2220217A1 (en) 1996-11-21
HUP9801139A3 (en) 1998-10-28
US6043328A (en) 2000-03-28
IL118237A0 (en) 1996-09-12
CN1186550A (zh) 1998-07-01
WO1996036890A1 (en) 1996-11-21
AU5814496A (en) 1996-11-29
EP0826158A1 (de) 1998-03-04
AR001497A1 (es) 1997-10-22
MX9708910A (es) 1998-03-31
NO975289L (no) 1998-01-16
KR19990021832A (ko) 1999-03-25
ATE184708T1 (de) 1999-10-15
ZA963937B (en) 1997-01-06
JPH11505564A (ja) 1999-05-21
SI0819258T1 (en) 2002-04-30
BR9608824A (pt) 1999-06-15
EP0826158B1 (de) 1999-09-15
DE29624309U1 (de) 2002-01-03
JP2011225884A (ja) 2011-11-10
JP5048173B2 (ja) 2012-10-17
CZ363997A3 (cs) 1998-03-18
DE69604285T2 (de) 2000-03-23

Similar Documents

Publication Publication Date Title
DE69604285D1 (de) Polysiloxan-polyol makromere, deren herstellung und verwendung
DE69728840D1 (de) Kojibiose Phosphorylase, deren Herstellung und Verwendung
DE69627411D1 (de) Triazinderivate, ihre Herstellung und Verwendung
DE69432330D1 (de) Metallocene, deren Herstellung und Verwendung
DE69627659D1 (de) Neue thrombin-inhibitoren, deren herstellung und verwendung
ATE383344T1 (de) Pyridazin-3-on derivate, deren verwendung und zwischenprodukte für deren herstellung
DE69529026D1 (de) Trehalose, ihre Herstellung und ihre Verwendung
ATE284392T1 (de) Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung
ATE249460T1 (de) 1,4-diazabicyclo(3.2.2)nonanderivate, deren herstellung und deren verwendung in heilkunde
DE69516913D1 (de) Anorganische harzzusammensetzungen, deren herstellung und deren verwendung
ATE239693T1 (de) 3,3-diarylpropylamine , ihre verwendung und herstellung
ATE302604T1 (de) Thienylazolylalkoxyethanamine, deren herstellung und deren verwendung als medikamente
DE59303423D1 (de) Wachsdispersionen, deren herstellung und verwendung
DE59800590D1 (de) Polymere organosiliciumverbindungen, deren herstellung und verwendung
DE69521595D1 (de) Optisch-aktives Benzothiepin-Derivate, ihre Herstellung und Verwendung
DE59409541D1 (de) Bicyclen-derivate, ihre herstellung und verwendung
DE59303537D1 (de) Reaktivfarbstoffe, deren Herstellung und Verwendung
DE59509446D1 (de) Reaktivfarbstoffe, deren Herstellung und Verwendung
DE59304510D1 (de) Reaktivfarbstoffe, deren Herstellung und Verwendung
DE69608477D1 (de) Organoaluminoxyprodukt, Katalysatorsystem, deren Herstellung und Verwendung
DE59409438D1 (de) Reaktivfarbstoffe, deren Herstellung und Verwendung
DE69410693D1 (de) Schäumbare Materialien, deren Herstellung und Verwendung
DE69723463D1 (de) Cyclische organoselenderivate, ihre herstellung und verwendung
DE59608127D1 (de) Reaktivfarbstoffe, ihre Herstellung und Verwendung
DE59807020D1 (de) 1:2-chromkomplexfarbstoffe, deren herstellung und verwendung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN