[go: up one dir, main page]

DE69535590D1 - Für den bradykinin-b1-rezeptor kodierende dna - Google Patents

Für den bradykinin-b1-rezeptor kodierende dna

Info

Publication number
DE69535590D1
DE69535590D1 DE69535590T DE69535590T DE69535590D1 DE 69535590 D1 DE69535590 D1 DE 69535590D1 DE 69535590 T DE69535590 T DE 69535590T DE 69535590 T DE69535590 T DE 69535590T DE 69535590 D1 DE69535590 D1 DE 69535590D1
Authority
DE
Germany
Prior art keywords
receptor
bradykinin
recombinant
dna encoding
host cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69535590T
Other languages
English (en)
Other versions
DE69535590T2 (de
Inventor
David L Linemeyer
John W Hess
Joseph A Borkowski
Kathleen K Bierilo
John G Menke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22861167&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69535590(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE69535590D1 publication Critical patent/DE69535590D1/de
Application granted granted Critical
Publication of DE69535590T2 publication Critical patent/DE69535590T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69535590T 1994-04-15 1995-04-10 Für den bradykinin-b1-rezeptor kodierende dna Expired - Lifetime DE69535590T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US229418 1994-04-15
US08/229,418 US5712111A (en) 1994-04-15 1994-04-15 DNA encoding bradykinin B1 receptor
PCT/US1995/004464 WO1995028474A1 (en) 1994-04-15 1995-04-10 Dna encoding bradykinin b1 receptor

Publications (2)

Publication Number Publication Date
DE69535590D1 true DE69535590D1 (de) 2007-10-18
DE69535590T2 DE69535590T2 (de) 2008-05-29

Family

ID=22861167

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535590T Expired - Lifetime DE69535590T2 (de) 1994-04-15 1995-04-10 Für den bradykinin-b1-rezeptor kodierende dna

Country Status (8)

Country Link
US (4) US5712111A (de)
EP (1) EP0757716B1 (de)
JP (1) JP2001506481A (de)
AT (1) ATE372375T1 (de)
CA (1) CA2187740C (de)
DE (1) DE69535590T2 (de)
ES (1) ES2292168T3 (de)
WO (1) WO1995028474A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712111A (en) * 1994-04-15 1998-01-27 Merck & Co., Inc. DNA encoding bradykinin B1 receptor
SE9602822D0 (sv) * 1996-07-19 1996-07-19 Astra Pharma Inc New receptor
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6469150B1 (en) * 2000-05-22 2002-10-22 Pharmacopeia, Inc. Cloning and characterization of genes encoding bradykinin B1 receptor homologues from five mammalian species
JP2005502341A (ja) * 2001-08-20 2005-01-27 メルク　エンド　カムパニー　インコーポレーテッド Ｂ１ブラジキニン受容体タンパク質を調節するための動物モデルとしてのトランスジェニックげっ歯類
US20090007283A1 (en) * 2003-10-08 2009-01-01 Hess John W Transgenic Rodents Selectively Expressing Human B1 Bradykinin Receptor Protein
US20080095849A1 (en) * 2005-04-25 2008-04-24 Amgen Inc. Peptide sustained release compositions and uses thereof
CN103339150A (zh) * 2010-12-03 2013-10-02 代阿麦迪卡股份有限公司 抗缓激肽b2受体(bkb2r)单克隆抗体
WO2013173923A1 (en) 2012-05-25 2013-11-28 Diamedica, Inc. Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
ES2625548T3 (es) 2012-06-04 2017-07-19 DiaMedica Therapeutics Inc. Isoformas de glicosilación de la calicreína-1 tisular humana
KR20190122706A (ko) 2017-03-09 2019-10-30 다이어메디카 인코포레이티드 조직 칼리크레인 1의 투약 형태

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712111A (en) * 1994-04-15 1998-01-27 Merck & Co., Inc. DNA encoding bradykinin B1 receptor

Also Published As

Publication number Publication date
US5712111A (en) 1998-01-27
CA2187740A1 (en) 1995-10-26
WO1995028474A1 (en) 1995-10-26
EP0757716A4 (de) 1999-07-21
ES2292168T3 (es) 2008-03-01
CA2187740C (en) 2010-06-29
US6307027B1 (en) 2001-10-23
EP0757716B1 (de) 2007-09-05
US20030036633A1 (en) 2003-02-20
US5965367A (en) 1999-10-12
DE69535590T2 (de) 2008-05-29
JP2001506481A (ja) 2001-05-22
ATE372375T1 (de) 2007-09-15
EP0757716A1 (de) 1997-02-12

Similar Documents

Publication Publication Date Title
ATE282087T1 (de) Modifiziertes enzym mit lipolytischer aktivität
DE69535590D1 (de) Für den bradykinin-b1-rezeptor kodierende dna
ATE404583T1 (de) Funktionelle antagonisten von hedgehog-aktivität
DE69531302D1 (de) Zellsystem mit einer spezifischen wechselwirkung von peptid-bindenden paaren
EA200001023A1 (ru) Специфическое в отношении fapa-(протеин альфа активации фибробласта) антитело с повышенной продуктивностью
EP0871703A4 (de) Dna kodierend für glutaminsäure-bewachte chloridkanäle
IL193919A0 (en) DcR3 POLYPEPTIDE A TNFR HOMOLOG
CA2321177A1 (en) Recombinant fibronectin-based extracellular matrix for wound healing
DE69434612D1 (de) Monoklonale Antikörper gegen recombinantes Stratum Corneum chymotryptisches Enzym (SCCE)
DE69431805D1 (de) Struktur höherer ordnung und bindung von peptidnukleinsäuren
NO990086D0 (no) Avkortete, oppl÷selige tumornekrosefaktorreseptorer av type I og type II
AR053931A2 (es) Secuencia de adn que codifica una proteina de a. thaliana que posee actividad de delta -5,7-esterol, delta-7-reductasa, proteina delta-7red
DE69535641D1 (de) Morphogene protein-spezifische zelloberflächenrezeptoren und ihre verwendungen
ATE282713T1 (de) Screening-verfahren zur identifizierung von neuen antibiotika
DE69529822D1 (de) Interleukin-15-rezeptoren
DK0804558T3 (da) Tripeptidylaminopeptidase
WO1994020512A3 (en) Analogs for specific oligosaccharide-protein interactions and uses therefor
PT654083E (pt) Subfamilia ptp-d das proteina-tirosina fosfatases
WO1999025878A3 (en) Methods for modulating and identifying cellular senescence
WO1994021800A3 (en) Protein tyrosine phosphatase ptp-s31
DE69737651D1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
DE59508100D1 (de) Verwendung von zelladhäsions-peptiden zur modifikation des haftungsvermögens eukaryontischer zellen untereinander
FR2716205B1 (fr) Récepteur galanine, acides nucléiques, cellules transformées et utilisations.
DE60033297D1 (de) Für die humane untereinheit 5-ht3-c des serotoninrezeptors 5-ht3 kodierende dna
AU2172597A (en) Protein phosphatase-1 catalytic subunit interactions

Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, N.J., US

8328 Change in the person/name/address of the agent

Representative=s name: MARKS & CLERK (LUXEMBOURG) LLP, LUXEMBOURG, LU