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DE69529822D1 - Interleukin-15-rezeptoren - Google Patents

Interleukin-15-rezeptoren

Info

Publication number
DE69529822D1
DE69529822D1 DE69529822T DE69529822T DE69529822D1 DE 69529822 D1 DE69529822 D1 DE 69529822D1 DE 69529822 T DE69529822 T DE 69529822T DE 69529822 T DE69529822 T DE 69529822T DE 69529822 D1 DE69529822 D1 DE 69529822D1
Authority
DE
Germany
Prior art keywords
interleukin
receptors
disclosed
dnas
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529822T
Other languages
English (en)
Other versions
DE69529822T2 (de
Inventor
Dirk M Anderson
Judith G Giri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of DE69529822D1 publication Critical patent/DE69529822D1/de
Publication of DE69529822T2 publication Critical patent/DE69529822T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69529822T 1994-05-06 1995-05-04 Interleukin-15-rezeptoren Expired - Lifetime DE69529822T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23691994A 1994-05-06 1994-05-06
US08/300,903 US5591630A (en) 1994-05-06 1994-09-06 Monoclonal antibodies that bind interleukin-15 receptors
PCT/US1995/005585 WO1995030695A1 (en) 1994-05-06 1995-05-04 Interleukin-15 receptors

Publications (2)

Publication Number Publication Date
DE69529822D1 true DE69529822D1 (de) 2003-04-10
DE69529822T2 DE69529822T2 (de) 2003-12-11

Family

ID=26930223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529822T Expired - Lifetime DE69529822T2 (de) 1994-05-06 1995-05-04 Interleukin-15-rezeptoren

Country Status (11)

Country Link
US (1) US5591630A (de)
EP (1) EP0759942B1 (de)
AT (1) ATE233788T1 (de)
AU (1) AU695798B2 (de)
CA (1) CA2188279C (de)
DE (1) DE69529822T2 (de)
DK (1) DK0759942T3 (de)
ES (1) ES2193192T3 (de)
NZ (1) NZ285292A (de)
PT (1) PT759942E (de)
WO (1) WO1995030695A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548065B1 (en) * 1994-05-06 2003-04-15 Immunex Corporation Interleukin-15 receptors
US5795966A (en) * 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
US6083477A (en) * 1996-10-17 2000-07-04 Immunomedics, Inc. Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
DE69830257T3 (de) 1997-02-21 2009-10-15 Amgen Inc., Thousand Oaks Verwendung von Interleukin-15
WO2000001851A1 (en) * 1998-07-07 2000-01-13 Hisamitsu Pharmaceutical Co., Inc. Antisense oligonucleotides targeted to il-15
AU4542801A (en) * 2000-03-03 2001-09-17 Univ Utah Res Found Mass1 gene, a target for anticonvulsant drug development
US7247304B2 (en) * 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
BR0212136A (pt) * 2001-08-23 2004-12-07 Genmab As Anticorpo monoclonal humano isolado, métodos para inibir a produção de tnfa em células t ou monócitos e a proliferação de célula t, hibridoma, transfectoma, animal não humano transgênico, método para produzir um anticorpo monoclonal humano, composição farmacêutica, métodos para tratar ou prevenir um distúrbio mediado pela il-15 humana, a psorìase e a artrite reumatóide, método para diagnosticar uma doença, ácido nucleico, e, vetor de expressão
US7329405B2 (en) * 2001-08-23 2008-02-12 Genmab A/S Human antibodies specific for interleukin 15 (IL-15)
PT1899364T (pt) 2005-05-17 2020-05-20 Univ Connecticut Composições e métodos para imunomodulação num organismo
EP1777294A1 (de) 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi Domäin als selektieve und potente Enhancer von IL-15 Aktion durch IL-15Rbeta/gamma, und Hyperagonist (IL15Ralpha sushi -IL15) Fusionsproteine
JP5709356B2 (ja) 2006-01-13 2015-04-30 アメリカ合衆国 哺乳動物細胞における発現のためのコドン最適化ＩＬ−１５およびＩＬ−１５Ｒ−α遺伝子
NZ703668A (en) 2007-06-27 2016-07-29 Us Sec Dep Of Health And Human Services Complexes of il-15 and il-15ralpha and uses thereof
ES2598005T3 (es) 2009-08-14 2017-01-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Uso de IL-15 para aumentar la salida del timo y para tratar la linfopenia
WO2011031986A1 (en) 2009-09-10 2011-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Assays for soluble il-15 receptor alpha
AU2013334610B2 (en) 2012-10-24 2018-09-13 Novartis Ag IL-15R alpha forms, cells expressing IL-15R alpha forms, and therapeutic uses of IL-15R alpha and IL-15/IL-15R alpha complexes
HUE058364T2 (hu) 2013-04-19 2022-07-28 Cytune Pharma Citokinbõl származó kezelés redukált vaszkuláris permeabilitási szindrómával
US10335460B2 (en) 2014-07-29 2019-07-02 Novartis Ag IL-15 and IL-15Rα heterodimer dose escalation regimens for treating conditions
EP3468581A1 (de) 2016-06-13 2019-04-17 Torque Therapeutics, Inc. Verfahren und zusammensetzungen zur förderung der immunzellenfunktionen
JP7285828B2 (ja) 2017-09-05 2023-06-02 トルク セラピューティクス， インコーポレイテッド 治療用タンパク質組成物ならびにその作製および使用方法
CN112795543B (zh) * 2021-02-04 2022-09-27 华中农业大学 杂交瘤细胞株及其分泌的抗草鱼IL-15Rα单克隆抗体和应用
WO2024040132A2 (en) 2022-08-16 2024-02-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Synergistic interactions for improved cancer treatment

Also Published As

Publication number Publication date
DK0759942T3 (da) 2003-06-10
EP0759942A4 (de) 1999-05-12
ATE233788T1 (de) 2003-03-15
DE69529822T2 (de) 2003-12-11
CA2188279C (en) 2010-01-26
WO1995030695A1 (en) 1995-11-16
NZ285292A (en) 1998-08-26
CA2188279A1 (en) 1995-11-16
US5591630A (en) 1997-01-07
EP0759942A1 (de) 1997-03-05
AU695798B2 (en) 1998-08-20
AU2434495A (en) 1995-11-29
ES2193192T3 (es) 2003-11-01
PT759942E (pt) 2003-07-31
EP0759942B1 (de) 2003-03-05

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