[go: up one dir, main page]

ES2193192T3 - Receptores de interleuquina-15. - Google Patents

Receptores de interleuquina-15.

Info

Publication number
ES2193192T3
ES2193192T3 ES95918389T ES95918389T ES2193192T3 ES 2193192 T3 ES2193192 T3 ES 2193192T3 ES 95918389 T ES95918389 T ES 95918389T ES 95918389 T ES95918389 T ES 95918389T ES 2193192 T3 ES2193192 T3 ES 2193192T3
Authority
ES
Spain
Prior art keywords
interleuquine
receivers
il15r
adns
recombinating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95918389T
Other languages
English (en)
Inventor
Dirk M Anderson
Judith G Giri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ES2193192T3 publication Critical patent/ES2193192T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE DESCRIBEN PROTEINAS DEL RECEPTOR DE LA INTERLEUQUINA-15 (IL15R), ADNS Y VECTORES DE EXPRESION QUE CODIFICAN LA IL-15R, Y PROCESOS PARA LA PRODUCCION DE IL-15R COMO PRODUCTOS DE CULTIVOS DE CELULAS RECOMBINANTES.
ES95918389T 1994-05-06 1995-05-04 Receptores de interleuquina-15. Expired - Lifetime ES2193192T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23691994A 1994-05-06 1994-05-06
US08/300,903 US5591630A (en) 1994-05-06 1994-09-06 Monoclonal antibodies that bind interleukin-15 receptors

Publications (1)

Publication Number Publication Date
ES2193192T3 true ES2193192T3 (es) 2003-11-01

Family

ID=26930223

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95918389T Expired - Lifetime ES2193192T3 (es) 1994-05-06 1995-05-04 Receptores de interleuquina-15.

Country Status (11)

Country Link
US (1) US5591630A (es)
EP (1) EP0759942B1 (es)
AT (1) ATE233788T1 (es)
AU (1) AU695798B2 (es)
CA (1) CA2188279C (es)
DE (1) DE69529822T2 (es)
DK (1) DK0759942T3 (es)
ES (1) ES2193192T3 (es)
NZ (1) NZ285292A (es)
PT (1) PT759942E (es)
WO (1) WO1995030695A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548065B1 (en) * 1994-05-06 2003-04-15 Immunex Corporation Interleukin-15 receptors
US5795966A (en) * 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
JP2001503253A (ja) 1996-10-17 2001-03-13 イムノメディクス，インコーポレイテッド 非抗原性即素複合体およびインターナライジング受容体システムの融合タンパク
ES2187946T3 (es) * 1997-02-21 2003-06-16 Vlaams Interuniv Inst Biotech Uso de interleucina-15.
EP1102862A4 (en) * 1998-07-07 2002-05-08 Hisamitsu Pharmaceutical Co ANTI-SENSE OLIGONUCLEOTIDES TARGETING IL-15
CA2401979A1 (en) * 2000-03-03 2001-09-13 University Of Utah Research Foundation Mass1 gene, a target for anticonvulsant drug development
US7247304B2 (en) * 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
SI1425389T1 (sl) * 2001-08-23 2012-02-29 Genmab As Humana protitelesa, specifična za interlevkin 15 (IL-15)
US7329405B2 (en) * 2001-08-23 2008-02-12 Genmab A/S Human antibodies specific for interleukin 15 (IL-15)
US8124084B2 (en) 2005-05-17 2012-02-28 University Of Connecticut Compositions and methods for immunomodulation in an organism using IL-15 and soluble IL-15Ra
EP1777294A1 (en) 2005-10-20 2007-04-25 Institut National De La Sante Et De La Recherche Medicale (Inserm) IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
US9303080B2 (en) 2006-01-13 2016-04-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells
NZ703668A (en) 2007-06-27 2016-07-29 Us Sec Dep Of Health And Human Services Complexes of il-15 and il-15ralpha and uses thereof
CA2768965C (en) 2009-08-14 2019-06-04 George N. Pavlakis Use of il-15 to increase thymic output and to treat lymphopenia
WO2011031986A1 (en) 2009-09-10 2011-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Assays for soluble il-15 receptor alpha
JP6359019B2 (ja) 2012-10-24 2018-07-18 ノバルティス アーゲー ＩＬ−１５Ｒα型、ＩＬ−１５Ｒα型を発現する細胞、ならびにＩＬ−１５ＲαおよびＩＬ−１５／ＩＬ−１５Ｒα複合体の治療上の使用
KR20150145260A (ko) 2013-04-19 2015-12-29 싸이튠 파마 감소된 혈관 누출 증후근에 대한 사이토카인 유도체 치료
WO2016018920A1 (en) 2014-07-29 2016-02-04 Admune Therapeutics Llc Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions
JP7185530B2 (ja) 2016-06-13 2022-12-07 トルク セラピューティクス， インコーポレイテッド 免疫細胞機能を促進するための方法および組成物
JP7285828B2 (ja) 2017-09-05 2023-06-02 トルク セラピューティクス， インコーポレイテッド 治療用タンパク質組成物ならびにその作製および使用方法
CN112795543B (zh) * 2021-02-04 2022-09-27 华中农业大学 杂交瘤细胞株及其分泌的抗草鱼IL-15Rα单克隆抗体和应用
WO2024040132A2 (en) 2022-08-16 2024-02-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Synergistic interactions for improved cancer treatment

Also Published As

Publication number Publication date
DE69529822D1 (de) 2003-04-10
CA2188279A1 (en) 1995-11-16
EP0759942A1 (en) 1997-03-05
US5591630A (en) 1997-01-07
EP0759942A4 (en) 1999-05-12
PT759942E (pt) 2003-07-31
CA2188279C (en) 2010-01-26
DE69529822T2 (de) 2003-12-11
AU695798B2 (en) 1998-08-20
EP0759942B1 (en) 2003-03-05
WO1995030695A1 (en) 1995-11-16
ATE233788T1 (de) 2003-03-15
DK0759942T3 (da) 2003-06-10
AU2434495A (en) 1995-11-29
NZ285292A (en) 1998-08-26

Similar Documents

Publication Publication Date Title
ES2193192T3 (es) Receptores de interleuquina-15.
AR241314A1 (es) Aislado de adn, vector en base en dicho aislado cultivo de celulas tratadas con dicho vector y preparacion de factor viii humano funcional.
ES2145451T3 (es) Secuencia de dna y proteina de cancer de mamas codificada especifica para mamas.
DE69739366D1 (de) Aktive und inactive CC-Chemokinrezeptoren und Nukleinsäuremoleküle, die für diesen Rezeptor kodieren
DE59712873D1 (de) Halogenpyrimidinylaryl(thio)ether als pestizide
DE69426033D1 (de) Für die alpha-1e untereinheit des menschlichen kalziumkanals kodierende dna
NO900770L (no) Produksjon av glykoseoksidase i rekombinante systemer.
DE3586697D1 (en) Aktive thymopentin-analoga.
DE69413039D1 (de) Prostaglandin rezeptor fp und kodierende dns
ATE236932T1 (de) Dna kodierend für prostaglandin rezeptor ip
ES2125864T3 (es) Vectores bacterianos.
ES2191011T3 (es) Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes.
DK0952853T3 (da) Konjugat omfattende et aktivt middel, et polypeptid og en polyether
TR199802512T2 (xx) Plastik par�alar�n asamblaj�n�n y�ksek h�zda asamblaj� i�in proses.
ES2061787T3 (es) Combinacion de inhibidores de la enzima de conversion de la angiotensina con moduladores del canal del potasio, asi como su empleo en medicamentos.
DE69120390D1 (de) Kollagen-bindendes protein sowie dessen herstellung
ES2048142T3 (es) Procedimiento de obtencion de polidesoxirribonucleotidos sustancialmente puros y no informacionales que tienen actividades biologicas, y producto respectivo.
FR2744730B1 (fr) Nouvelle famille de canaux potassium de mammifere, leur clonage et leur utilisation notamment pour le criblage de drogues
ES2175246T3 (es) Reticulante pobre en reversion.
HUT41002A (en) Process for preparing anticonvulsives
PE20399A1 (es) Muteina ob
ES2183515T3 (es) Peptidomimeticos de azol utilizados como antagonistas del receptor de la trombina.
ATE207757T1 (de) Für die immun- und cns-therapie nutzbare, neuartige tripeptide
ES2193399T3 (es) Derivados del acido nodulisporico.
ES2136199T3 (es) Expresion multicistronica de genes recombinantes en celulas bacterianas.